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Results for the Protein: Q9BUB5
30316115

MKNK1_HUMAN RecName: Full=MAP kinase-interacting serine/threonine-protein kinase 1; AltName: Full=MAP kinase signal-integrating kinase 1; Short=MAPK signal-integrating kinase 1; Short=Mnk1
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STKc_ROCK1 - cd05622
STKc_ROCK - cd05596
STKc_PAK_II - cd06648
STKc_ROCK2 - cd05621
STKc_PAK1 - cd06654
STKc_JNK2 - cd07876
STKc_PAK3 - cd06656
STKc_PAK - cd06614
STKc_PAK2 - cd06655
STKc_JNK1 - cd07875
STKc_JNK - cd07850
STKc_PAK_I - cd06647
STKc_PAK5 - cd06658
STKc_myosinIIIB - cd06639
STKc_PAK4 - cd06657
STKc_p38beta_MAPK11 - cd07878
STKc_PAK6 - cd06659
STKc_STK10_LOK - cd06644
STKc_myosinIIIA - cd06638
STKc_p38gamma_MAPK12 - cd07880
STKc_p38 - cd07851
STKc_CDC2L1 - cd07843
STKc_MAPK4_6 - cd07854
STKc_MAPK15 - cd07852
STKc_Sty1_Hog1 - cd07856
STKc_CDK10 - cd07845
STKc_CDKL1_4 - cd07847
STKc_PCTAIRE3 - cd07871
STKc_PCTAIRE_like - cd07844
STKc_CDK12 - cd07864
STKc_CDKL - cd07833
PKc_MAPKK_Pek1_like - cd06621
PKc_MKK7 - cd06618
STKc_SLK - cd06643
STKc_Nek1 - cd08218
STKc_FA2-like - cd08529
STKc_TEY_MAPK_plant - cd07858
STKc_ERK5 - cd07855
STKc_CDK5 - cd07839
STKc_ASK - cd06624
STKc_ERK1_2_like - cd07849
STKc_TNIK - cd06637
STKc_BUR1 - cd07866
PKc_MKK4 - cd06616
STKc_CMGC - cd05118
STKc_MST1_2 - cd06612
STKc_MAP4K3_like - cd06613
STKc_SLK_like - cd06611
PKc_MAPKK - cd06605
PKc_MAPKK_plant_like - cd06623
SPS1 - COG0515
STKc_NDR1 - cd05628
STKc_MEKK2 - cd06652
PKc_MAPKK_PBS2_like - cd06622
STKc_phototropin_lik - cd05574
STKc_NDR2 - cd05627
STKc_DMPK_like - cd05597
STKc_MAST - cd05609
STKc_MRCK_beta - cd05624
STKc_MRCK_alpha - cd05623
STKc_NAK1_like - cd06917
STKc_Pho85 - cd07836
STKc_MEKK3 - cd06651
STKc_CdkB_plant - cd07837
STKc_Nek6_Nek7 - cd08224
PKc_MEK - cd06615
STKc_CDK1_euk - cd07861
STKc_CDK2_3 - cd07860
STKc_CDKL2_3 - cd07846
STKc_NDR_like_fungal - cd05629
STKc_PRKX_like - cd05612
STKc_cPKC - cd05587
STKc_OSR1_SPAK - cd06610
STKc_ROCK_NDR_like - cd05573
STKc_cPKC_beta - cd05616
STKc_PKA - cd05580
STKc_MST3_like - cd06609
STKc_myosinIII_like - cd06608
STKc_LATS - cd05598
STKc_Nek - cd08215
STKc_CDK4 - cd07863
STKc_TDY_MAPK_plant - cd07859
STKc_Nek3 - cd08219
STKc_Nek10 - cd08528
STKc_CNK2-like - cd08530
STKc_MPK1 - cd07857
STKc_Nek5 - cd08225
STKc_Nek8 - cd08220
STKc_MSK_N - cd05583
STKc_MSK1_N - cd05613
PKc_STE - cd05122
STKc_CDK8_like - cd07842
STKc_MAPKKK - cd06606
STKc_MSK2_N - cd05614
STKc_Cdc7_like - cd06627
STKc_CDK7 - cd07841
STKc_MAPK - cd07834
STKc_CCRK - cd07832
STKc_CDK4_6_like - cd07838
STKc_CDK9_like - cd07840
Pkinase_Tyr - pfam07714
STKc_CDK1_like - cd07835
STKc_CDK_like - cd07829
STKc_MAPKKK_Byr2_lik - cd06628
STKc_PKN - cd05589
STKc_cPKC_alpha - cd05615
STKc_MOK - cd07831
STKc_MAK_like - cd07830
Pkinase - pfam00069
TyrKc - smart00219
STYKc - smart00221
STKc_CRIK - cd05601
STKc_GRK5 - cd05632
STKc_GRK4_like - cd05605
STKc_NLK - cd07853
STKc_MEKK4 - cd06626
STKc_RSK_N - cd05582
STKc_p70S6K - cd05584
STKc_nPKC_delta - cd05620
STKc_GRK4 - cd05631
STKc_aPKC_zeta - cd05617
STKc_aPKC_iota - cd05618
STKc_nPKC_theta - cd05619
STKc_MEKK1 - cd06630
STKc_Nek2 - cd08217
STKc_SGK3 - cd05604
STKc_MEKK1_plant - cd06632
STKc_YSK4 - cd06631
STKc_MAPKKK_Bck1_lik - cd06629
STKc_MEKK3_like - cd06625
STKc_PKB_gamma - cd05593
STKc_Yank1 - cd05578
STKc_PDK1 - cd05581
STKc_aPKC - cd05588
PTKc - cd00192
STKc_PKC - cd05570
STKc_PKB - cd05571
STKc_SGK2 - cd05603
STKc_nPKC_eta - cd05590
STKc_nPKC_epsilon - cd05591
STKc_Sid2p_Dbf2p - cd05600
STKc_SGK1 - cd05602
STKc_NDR_like - cd05599
STKc_PKB_beta - cd05595
STKc_nPKC_theta_delt - cd05592
STKc_PKB_alpha - cd05594
STKc_SGK - cd05575
STKc_Nek9 - cd08221
STKc_GRK3 - cd05633
STKc_beta_ARK - cd05606
STKc_AGC - cd05123
PKc - cd00180
STKc_cGK_PKG - cd05572
STKc_Sck1_like - cd05586
STKc_GRK - cd05577
STKc_MAST_like - cd05579
STKc_YPK1_like - cd05585
STKc_GRK1 - cd05608
STKc_Rim15_like - cd05611
S_TKc - smart00220
PKc_MKK3_6 - cd06617


Swiss-Prot Protein: Q9BUB5
Identical to: NP_003675
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
STKc_ROCK1cd056220.000845441
STKc_ROCKcd055960.0004417435
STKc_ROCK2cd056210.0001923435
STKc_PAK_IIcd066482.4e-0723388
STKc_PAK1cd066546.9e-0524398
STKc_PAKcd066146.7e-1525388
STKc_PAK2cd066555.8e-0625410
STKc_PAK3cd066569.4e-0625395
STKc_JNK2cd078760.0001525413
STKc_JNK1cd078750.0003326409
STKc_PAK_Icd066473.2e-0527396
STKc_JNKcd078502.8e-0527411
STKc_PAK5cd066580.0003328392
STKc_myosinIIIBcd066393.4e-0529375
STKc_PAK6cd066592e-0630396
STKc_PAK4cd066570.0008330394
STKc_p38beta_MAPK11cd078780.0006930416
STKc_myosinIIIAcd066383.9e-0532374
STKc_STK10_LOKcd066445.7e-0532395
STKc_p38gamma_MAPK12cd078800.000133416
STKc_p38cd078516.6e-0736416
STKc_CDC2L1cd078430.0001238374
STKc_MAPK4_6cd078540.0006740411
STKc_Sty1_Hog1cd078565.6e-0540403
STKc_MAPK15cd078522.1e-0740424
PKc_MKK7cd066186e-0742391
PKc_MAPKK_Pek1_likecd066210.0001342389
STKc_SLKcd066432.2e-0542394
STKc_CDKLcd078332.1e-0842374
STKc_PCTAIRE_likecd078440.0001242374
STKc_CDK10cd078450.0001242386
STKc_CDKL1_4cd078476.9e-0742374
STKc_CDK12cd078647.7e-0642374
STKc_PCTAIRE3cd078710.0001742374
STKc_ASKcd066242.4e-0543374
STKc_CDK5cd078390.0001243374
STKc_ERK5cd078553.4e-0543423
STKc_TEY_MAPK_plantcd078587.1e-0543416
STKc_Nek1cd082180.0001443374
STKc_FA2-likecd085299.4e-0543374
STKc_CMGCcd051183.9e-1344374
STKc_MST1_2cd066121.4e-0944374
STKc_MAP4K3_likecd066131.7e-1044373
PKc_MKK4cd066163e-0644389
STKc_TNIKcd066370.0004344374
STKc_ERK1_2_likecd078499.6e-0544422
STKc_BUR1cd078660.0004744374
STKc_phototropin_likcd055744e-1145396
STKc_DMPK_likecd055976.9e-0745439
STKc_MASTcd056091.6e-0645429
STKc_MRCK_alphacd056232.8e-0545435
STKc_MRCK_betacd056240.0001145445
STKc_NDR2cd056270.0001245459
STKc_NDR1cd056281.1e-0545437
PKc_MAPKKcd066051.9e-0645379
STKc_SLK_likecd066115.2e-1045391
PKc_MAPKK_PBS2_likecd066221.8e-0645423
PKc_MAPKK_plant_likecd066231e-1245381
STKc_MEKK2cd066520.0009945375
SPS1COG05159.1e-3945463
STKc_ROCK_NDR_likecd055732e-1146429
STKc_PKAcd055805.4e-1346404
STKc_cPKCcd055875.2e-0746435
STKc_PRKX_likecd056121.9e-0846402
STKc_cPKC_betacd056165.2e-0546431
STKc_NDR_like_fungalcd056293.6e-0646449
STKc_LATScd055989.6e-0646450
STKc_myosinIII_likecd066083.2e-0746374
STKc_MST3_likecd066091.5e-1146395
STKc_OSR1_SPAKcd066107e-1046374
PKc_MEKcd066150.000346396
STKc_MEKK3cd066518.3e-0546376
STKc_NAK1_likecd069173.9e-0946393
STKc_Pho85cd078366e-0546374
STKc_CdkB_plantcd078372.2e-0846375
STKc_CDKL2_3cd078461.6e-0846374
STKc_CDK2_3cd078600.000346374
STKc_CDK1_eukcd078615.5e-0646374
STKc_Nek6_Nek7cd082241.7e-0546378
PKc_STEcd051227.4e-1647373
STKc_MSK_Ncd055832.1e-0947389
STKc_MSK1_Ncd056131.1e-0847389
STKc_MSK2_Ncd056147.2e-0847436
STKc_MAPKKKcd066062.7e-1847374
STKc_Cdc7_likecd066271.1e-1247374
STKc_CCRKcd078325.6e-1247375
STKc_MAPKcd078341.9e-0847410
STKc_CDK7cd078411.7e-0747384
STKc_CDK8_likecd078420.0003547374
STKc_MPK1cd078575.2e-0647420
STKc_TDY_MAPK_plantcd078591.9e-0647422
STKc_CDK4cd078630.0006447374
STKc_Nekcd082152.2e-1547374
STKc_Nek3cd082191.5e-0547374
STKc_Nek8cd082206.2e-0547374
STKc_Nek5cd082250.0004747374
STKc_Nek10cd085280.0001747374
STKc_CNK2-likecd085302.3e-0747374
STKc_PKNcd055891.4e-0748434
STKc_cPKC_alphacd056153.6e-0648422
STKc_MAPKKK_Byr2_likcd066284.2e-0748374
STKc_MAK_likecd078302.1e-1048374
STKc_MOKcd078311.7e-1148374
STKc_CDK1_likecd078358.4e-0848374
STKc_CDK4_6_likecd078380.0001548374
STKc_CDK9_likecd078401.5e-0848374
STKc_CDK_likecd078291.6e-1148374
STKc_CRIKcd056012.1e-0850402
STKc_GRK4_likecd056056.7e-0551405
STKc_GRK5cd056320.0001951392
STKc_NLKcd078532.1e-0551443
STKc_RSK_Ncd055824.7e-0552434
STKc_p70S6Kcd055843.1e-0852436
STKc_MEKK4cd066261.3e-0952374
PTKccd001920.0001953373
STKc_PKCcd055704.4e-1253427
STKc_PKBcd055713.6e-0953441
STKc_SGKcd055751.5e-0753434
STKc_Yank1cd055782.8e-1353374
STKc_PDK1cd055811.4e-1953374
STKc_aPKCcd055888e-0853435
STKc_nPKC_etacd055904.8e-0753438
STKc_nPKC_epsiloncd055919.6e-0853435
STKc_nPKC_theta_deltcd055929.3e-1053439
STKc_PKB_gammacd055933.8e-0753449
STKc_PKB_alphacd055946.7e-0953438
STKc_PKB_betacd055952.2e-0653437
STKc_NDR_likecd055998.7e-0853402
STKc_Sid2p_Dbf2pcd056000.0001653420
STKc_SGK1cd056024.9e-0653403
STKc_SGK2cd056033.3e-0753438
STKc_SGK3cd056042.1e-0553439
STKc_aPKC_zetacd056176.6e-0753435
STKc_aPKC_iotacd056183.4e-0553435
STKc_nPKC_thetacd056195.1e-0853436
STKc_nPKC_deltacd056206.4e-0653436
STKc_GRK4cd056310.0009153392
STKc_MEKK3_likecd066252.3e-0953374
STKc_MAPKKK_Bck1_likcd066292.8e-0653374
STKc_MEKK1cd066300.0004453375
STKc_YSK4cd066312e-0553374
STKc_MEKK1_plantcd066323.8e-0853374
STKc_Nek2cd082173.1e-0953374
STKc_beta_ARKcd056060.0009854390
STKc_GRK3cd056330.0008554391
STKc_Nek9cd082217.9e-0554374
PKccd001802.1e-5855372
STKc_AGCcd051231e-1755374
STKc_cGK_PKGcd055721.8e-1055381
STKc_GRKcd055772.4e-0655380
STKc_MAST_likecd055791.2e-1455376
STKc_YPK1_likecd055851.1e-0855433
STKc_Sck1_likecd055863.5e-0655465
STKc_GRK1cd056084.8e-0555391
STKc_Rim15_likecd056116.8e-0758373
PKc_MKK3_6cd066175.6e-05116394
Pkinasepfam000694.6e-6049374
Pkinase_Tyrpfam077148.6e-0748372
STYKcsmart002214.5e-6149374
TyrKcsmart002191.5e-0649372
S_TKcsmart002207.8e-7559374

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_040804Polymorphismp.ARG446GLNN/A
Swiss-ProtVAR_040803Polymorphismp.ASP308ASNN/A
Swiss-ProtVAR_040802Polymorphismp.LEU158VALN/A
Swiss-ProtVAR_040801Polymorphismp.LYS49GLNN/A



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