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Results for the Protein: Q38SD2
313104220

LRRK1_HUMAN RecName: Full=Leucine-rich repeat serine/threonine-protein kinase 1
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 The Domains on the Default View are decided by the Domain's E-Value.

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ANK - cd00204
LRR_TYP - smart00369
LRR - smart00370
Arf - pfam00025
COG1100 - COG1100
Rab - cd00154
Miro - pfam08477
Ras_like_GTPase - cd00882
PTKc_Kit - cd05104
PTKc_PDGFR_alpha - cd05105
STKc_PAK - cd06614
STKc_TAO2 - cd06634
STKc_PAK1 - cd06654
STKc_PAK_I - cd06647
STKc_PAK2 - cd06655
STKc_PAK3 - cd06656
STKc_PAK6 - cd06659
STKc_p38beta_MAPK11 - cd07878
STKc_p38gamma_MAPK12 - cd07880
STKc_PAK_II - cd06648
PTKc_Tie2 - cd05088
STKc_p38 - cd07851
PTK_HER3 - cd05111
PTKc_EGFR_like - cd05057
STKc_JNK - cd07850
PKc_MKK7 - cd06618
PTKc_Ror - cd05048
PTKc_FGFR4 - cd05099
PTKc_FAK - cd05056
PTKc_Chk - cd05083
STKc_myosinIIIB - cd06639
STKc_BUR1 - cd07866
PTKc_HER2 - cd05109
PTKc_FGFR3 - cd05100
PTK_CCK4 - cd05046
PTKc_FGFR2 - cd05101
PTKc_HER4 - cd05110
STKc_ASK - cd06624
STKc_Nek6_Nek7 - cd08224
PTKc_InsR_like - cd05032
PKc_MAPKK_Byr1_like - cd06620
STKc_Nek7 - cd08229
PTKc_DDR_like - cd05097
PTKc_Musk - cd05050
PTKc_FGFR - cd05053
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_DDR1 - cd05096
PTKc_Tie1 - cd05089
PTKc_EphR - cd05033
PTKc_Jak_rpt2 - cd05038
STKc_CdkB_plant - cd07837
PTKc_ALK_LTK - cd05036
PTKc_FGFR1 - cd05098
PKc_MAPKK_plant_like - cd06623
PKc_MKK4 - cd06616
PKc_STE - cd05122
PKc_MEK2 - cd06649
STKc_MAP4K3_like - cd06613
PTKc_Csk_like - cd05039
PTKc_InsR - cd05061
PTKc_EGFR - cd05108
STKc_MST1_2 - cd06612
STKc_CDKL2_3 - cd07846
PTKc_Srm_Brk - cd05148
PTKc_DDR - cd05051
PTKc_DDR2 - cd05095
STKc_MST3_like - cd06609
STKc_SLK - cd06643
STKc_MEKK3_like_1 - cd06653
SPS1 - COG0515
STKc_PKA - cd05580
STKc_CDK9_like - cd07840
STKc_CDKL1_4 - cd07847
STKc_Nek1 - cd08218
STKc_CDK4 - cd07863
STKc_cPKC_alpha - cd05615
STKc_GRK4_like - cd05605
STKc_MAST - cd05609
STKc_TDY_MAPK_plant - cd07859
STKc_MAPKKK - cd06606
STKc_CDK5 - cd07839
PKc_MEK - cd06615
STKc_MAPK4_6 - cd07854
TyrKc - smart00219
STKc_FA2-like - cd08529
STYKc - smart00221
Pkinase - pfam00069
Pkinase_Tyr - pfam07714
STKc_MEKK1 - cd06630
STKc_CDK1_like - cd07835
STKc_CCRK - cd07832
STKc_YSK4 - cd06631
STKc_CDK7 - cd07841
STKc_MAK_like - cd07830
STKc_Nek8 - cd08220
STKc_MAPKKK_Byr2_lik - cd06628
STKc_MEKK3_like - cd06625
STKc_Nek10 - cd08528
STKc_Nek11 - cd08222
STKc_Sty1_Hog1 - cd07856
PTKc_Axl - cd05075
STKc_p70S6K - cd05584
STKc_PDK1 - cd05581
STKc_CDK10 - cd07845
PTKc_Axl_like - cd05035
STKc_MEKK4 - cd06626
PTKc_RET - cd05045
STKc_MAPKKK_Bck1_lik - cd06629
STKc_MEKK2 - cd06652
STKc_Cdc7_like - cd06627
STKc_MEKK1_plant - cd06632
STKc_cPKC_beta - cd05616
STKc_MSK1_N - cd05613
STKc_nPKC_eta - cd05590
PKc_MAPKK - cd06605
STKc_SGK2 - cd05603
STKc_CDKL - cd07833
STKc_nPKC_theta_delt - cd05592
STKc_Nek4 - cd08223
STKc_CDK8_like - cd07842
STKc_MAPK - cd07834
PTKc - cd00192
PTK_Jak2_Jak3_rpt1 - cd05078
PTKc_Fes_like - cd05041
PTK_Jak_rpt1 - cd05037
PTKc_c-ros - cd05044
PTKc_Tie - cd05047
PTK_Jak1_rpt1 - cd05077
PTKc_Met_Ron - cd05058
STKc_PKB_alpha - cd05594
PTKc_Fes - cd05084
STKc_cPKC - cd05587
STKc_PKN - cd05589
STKc_nPKC_epsilon - cd05591
STKc_PKB - cd05571
PTKc_Ack_like - cd05040
PTKc_Fer - cd05085
PTKc_Aatyk2 - cd05086
PTKc_Syk_like - cd05060
STKc_CDK_like - cd07829
STKc_beta_ARK - cd05606
STKc_Yank1 - cd05578
STKc_Nek9 - cd08221
STKc_OSR1_SPAK - cd06610
STKc_MOK - cd07831
STKc_Nek - cd08215
STKc_MPK1 - cd07857
STKc_myosinIIIA - cd06638
PTKc_Abl - cd05052
PKc - cd00180
STKc_GRK1 - cd05608
STKc_CMGC - cd05118
STKc_cGK_PKG - cd05572
STKc_AGC - cd05123
STKc_GRK - cd05577
STKc_MAST_like - cd05579
STKc_GRK7 - cd05607
PTKc_Tec_Rlk - cd05114
PTKc_EphR_A - cd05066
S_TKc - smart00220
PTKc_EphR_B - cd05065
PTKc_IGF-1R - cd05062
PTKc_Ror2 - cd05091
STKc_MEKK3 - cd06651
STKc_aPKC - cd05588
PTKc_Tyro3 - cd05074
STKc_SGK - cd05575
PTKc_TrkB - cd05093
PTKc_EphR_A2 - cd05063
PTKc_Frk_like - cd05068
STKc_STK10_LOK - cd06644
STKc_PCTAIRE_like - cd07844
PTKc_Syk - cd05116
STKc_RSK_N - cd05582
PTKc_EphR_A10 - cd05064
STKc_nPKC_theta - cd05619
STKc_MSK_N - cd05583
STKc_Nek3 - cd08219
STKc_Nek5 - cd08225
PTKc_Aatyk1_Aatyk3 - cd05087
PTKc_Lyn - cd05072
STKc_NLK - cd07853
PTKc_Zap-70 - cd05115
PTKc_Ror1 - cd05090
PTKc_Itk - cd05112
PTKc_Src - cd05071
PTKc_Yes - cd05069
PTKc_Csk - cd05082
PTK_Ryk - cd05043
PTKc_Lck_Blk - cd05067
PTKc_Fyn_Yrk - cd05070
PTKc_Hck - cd05073
PTKc_Trk - cd05049
PTKc_TrkA - cd05092
PTKc_Btk_Bmx - cd05113
PTKc_Src_like - cd05034
STKc_Nek6 - cd08228
PTKc_Tyk2_rpt2 - cd05080
STKc_CNK2-like - cd08530
PTKc_Aatyk - cd05042
STKc_PRKX_like - cd05612
PTKc_Tec_like - cd05059
STKc_SLK_like - cd06611
STKc_NAK1_like - cd06917
STKc_PKC - cd05570
STKc_Nek2 - cd08217
PKc_MAPKK_Pek1_like - cd06621


Swiss-Prot Protein: Q38SD2
Identical to: NP_078928
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
ANKcd002040.0001479214
COG1100COG11003.4e-05634904
Rabcd001544.2e-05639821
Ras_like_GTPasecd008829.1e-05643821
PTKc_Kitcd051040.0007711611524
PTKc_PDGFR_alphacd051050.0006611631524
STKc_PAKcd066141e-0912081529
STKc_TAO2cd066340.0003312161554
STKc_PAK1cd066540.0003112191546
STKc_PAK_Icd066470.0004712201540
STKc_PAK2cd066550.0003612201544
STKc_PAK3cd066560.000412201544
STKc_PAK6cd066590.0001712221541
STKc_p38beta_MAPK11cd078780.00112221587
STKc_p38gamma_MAPK12cd078800.0001712231588
STKc_PAK_IIcd066481.8e-0512261530
PTKc_Tie2cd050883.6e-0612271534
PTKc_EGFR_likecd050579.5e-0812291529
PTK_HER3cd051111.8e-0512291530
STKc_JNKcd078500.00112291590
STKc_p38cd078510.0001412291576
PTKc_Rorcd050484.7e-0912301523
PKc_MKK7cd066182.4e-0612301531
PTKc_FAKcd050561.1e-0812311528
PTKc_Chkcd050837.7e-0712311523
PTKc_FGFR4cd050992.8e-0612311544
STKc_myosinIIIBcd066390.0001612311526
PTK_CCK4cd050461.1e-0512321522
PTKc_FGFR2cd051010.0001412321531
PTKc_HER4cd051101.4e-0512321549
PTKc_FGFR3cd051000.0001412321554
PTKc_HER2cd051091e-0512321530
STKc_BUR1cd078661.6e-0512321541
PTKc_InsR_likecd050326e-1012331522
PTKc_Jak_rpt2cd050389.7e-0912331520
PTKc_FGFRcd050532.1e-0612331526
PTKc_Muskcd050501.4e-1012331522
PTKc_Jak2_Jak3_rpt2cd050812.7e-0612331524
PTKc_EphRcd050336.5e-0812331524
PTKc_Tie1cd050891.6e-0512331547
PTKc_DDR1cd050963.2e-0512331522
PTKc_DDR_likecd050970.0001112331522
PKc_MAPKK_Byr1_likecd066204e-0512331526
STKc_ASKcd066244.5e-0512331525
STKc_Nek6_Nek7cd082244.2e-0712331522
STKc_Nek7cd082299.3e-0812331522
STKc_CdkB_plantcd078376.6e-0712341542
PTKc_ALK_LTKcd050363.9e-0912351522
PTKc_FGFR1cd050985.9e-0512361531
PKc_MAPKK_plant_likecd066232.6e-0912361523
PKc_STEcd051221e-0912371525
PKc_MKK4cd066160.0003912371540
PKc_MEK2cd066490.000612371596
PTKc_Csk_likecd050391.1e-0612381523
PTKc_InsRcd050612e-0712381530
PTKc_EGFRcd051083.2e-0612381573
STKc_MST1_2cd066121.1e-0712381525
STKc_MAP4K3_likecd066132.2e-0712381518
PTKc_DDRcd050517.6e-0712391514
PTKc_DDR2cd050958.8e-0712391522
PTKc_Srm_Brkcd051481.6e-0712391523
STKc_MST3_likecd066098.3e-0612391537
STKc_SLKcd066430.0003312391538
STKc_MEKK3_like_1cd066530.000312391522
STKc_CDKL2_3cd078461.2e-0512391525
STKc_PKAcd055800.0002312401565
STKc_CDK9_likecd078405.9e-0712401541
STKc_CDKL1_4cd078471.5e-0512401552
SPS1COG05151.3e-2412401692
STKc_MASTcd056090.0008512411554
STKc_GRK4_likecd056055.9e-0512411545
STKc_cPKC_alphacd056150.0001112411555
STKc_MAPKKKcd066066.2e-1412411517
STKc_CDK5cd078390.0002512411551
STKc_TDY_MAPK_plantcd078590.0003812411598
STKc_CDK4cd078630.0001412411551
STKc_Nek1cd082180.0006312411525
PKc_MEKcd066157.8e-0512421572
STKc_MAPK4_6cd078540.0009612421575
STKc_FA2-likecd085294.1e-0812421517
STKc_YSK4cd066312.8e-0912431526
STKc_MEKK1cd066302.5e-0612431526
STKc_CCRKcd078322e-0812431530
STKc_CDK1_likecd078350.0002812431551
STKc_MAK_likecd078301.5e-0612431514
STKc_CDK7cd078412.9e-0512431516
STKc_Nek8cd082202.7e-0712431517
STKc_MEKK3_likecd066252e-1012441522
STKc_MAPKKK_Byr2_likcd066282.9e-0912441525
STKc_Nek10cd085284.3e-0712441522
PTKc_Axl_likecd050352e-0612451524
PTKc_RETcd050456e-0512451527
PTKc_Axlcd050750.0002412451524
STKc_PDK1cd055812.1e-0712451525
STKc_p70S6Kcd055844.1e-0612451587
STKc_MEKK4cd066263e-0912451526
STKc_MAPKKK_Bck1_likcd066291.8e-1012451526
STKc_MEKK1_plantcd066321.5e-0812451516
STKc_MEKK2cd066520.0003512451527
STKc_Cdc7_likecd066271.7e-1012451514
STKc_CDK10cd078455.6e-0512451526
STKc_Sty1_Hog1cd078564.9e-0612451575
STKc_Nek11cd082221.2e-0512451525
PTKccd001923.6e-1412461521
PTK_Jak_rpt1cd050373.6e-0612461521
PTKc_Fes_likecd050417.2e-1212461522
PTKc_c-roscd050441.6e-0612461522
PTKc_Tiecd050471.2e-0512461521
PTKc_Met_Roncd050582.2e-0712461526
PTKc_Syk_likecd050602.5e-1312461525
PTK_Jak1_rpt1cd050770.0001612461521
PTK_Jak2_Jak3_rpt1cd050787.7e-0712461521
PTKc_Fescd050848.6e-0812461523
PTKc_Fercd050851.1e-0812461522
PTKc_Aatyk2cd050861.6e-0512461522
PTKc_Ack_likecd050401.1e-1312461522
STKc_PKBcd055711.1e-0512461593
STKc_cPKCcd055870.0001312461555
STKc_PKNcd055894.2e-0512461585
STKc_nPKC_epsiloncd055910.0002112461566
STKc_PKB_alphacd055943.1e-0512461588
STKc_nPKC_theta_deltcd055924.3e-0512461587
STKc_SGK2cd056036.7e-0512461557
STKc_nPKC_etacd055900.0002712461586
STKc_MSK1_Ncd056130.0007612461543
STKc_cPKC_betacd056160.0008712461555
PKc_MAPKKcd066052.2e-0612461530
STKc_MAPKcd078340.0001512461555
STKc_CDK8_likecd078420.0002112461525
STKc_CDKLcd078332.8e-0712461525
STKc_Nek4cd082230.0005912461522
STKc_Yank1cd055788.2e-0812471526
STKc_beta_ARKcd056060.0001612471545
STKc_OSR1_SPAKcd066101.8e-0612471517
STKc_CDK_likecd078292.3e-0912471541
STKc_MOKcd078315.1e-0812471541
STKc_Nekcd082156.2e-1512471522
STKc_Nek9cd082218.1e-0812471522
PKccd001803.6e-4712481520
PTKc_Ablcd050522e-0712481524
STKc_CMGCcd051187.8e-1012481541
STKc_AGCcd051231.8e-0912481525
STKc_cGK_PKGcd055723.4e-0612481532
STKc_GRKcd055777e-0712481544
STKc_MAST_likecd055791.6e-0712481527
STKc_GRK7cd056070.0006212481549
STKc_GRK1cd056083.4e-0612481544
STKc_myosinIIIAcd066380.0007412481522
STKc_MPK1cd078570.0003812481567
PTKc_EphR_Acd050669.3e-0612511524
PTKc_Tec_Rlkcd051144.2e-0712511521
PTKc_EphR_Bcd050651.2e-0612531524
PTKc_IGF-1Rcd050624.8e-0612531522
PTKc_Ror2cd050919.1e-0812541523
STKc_MEKK3cd066511.2e-0512541520
PTKc_Tyro3cd050745.5e-0612551524
STKc_SGKcd055750.000312551565
STKc_aPKCcd055880.0001612551615
PTKc_EphR_A2cd050631.8e-0512571524
PTKc_Frk_likecd050684e-1212571523
PTKc_TrkBcd050931e-0512571532
STKc_STK10_LOKcd066440.0001712571540
STKc_PCTAIRE_likecd078440.0001212581552
PTKc_Sykcd051161.3e-0712591525
STKc_RSK_Ncd055824.4e-0512601584
PTKc_Aatyk1_Aatyk3cd050870.0002512611522
PTKc_EphR_A10cd050640.000412611521
STKc_MSK_Ncd055835.7e-0512611543
STKc_nPKC_thetacd056196.2e-0512611580
STKc_Nek5cd082250.0002512611525
STKc_Nek3cd082192.5e-0712611522
PTKc_Lyncd050723.9e-0712631523
PTKc_Zap-70cd051159.9e-0812631525
STKc_NLKcd078530.0003712631594
PTKc_Ror1cd050907.5e-0812641523
PTKc_Itkcd051122.1e-0712651521
PTKc_Yescd050693.5e-0612661523
PTKc_Srccd050712e-0512661526
PTK_Rykcd050435.1e-0512671529
PTKc_Lck_Blkcd050673.2e-0512671523
PTKc_Fyn_Yrkcd050704.3e-0512671523
PTKc_Hckcd050739.7e-0912671523
PTKc_Cskcd050820.0004512671523
PTKc_Trkcd050492.6e-0812681522
PTKc_TrkAcd050921.5e-0512681529
PTKc_Src_likecd050341.1e-0812691523
PTKc_Btk_Bmxcd051135e-0812691521
STKc_Nek6cd082281.9e-0512691522
PTKc_Tyk2_rpt2cd050801.3e-0512701525
STKc_CNK2-likecd085309.2e-0912711517
PTKc_Aatykcd050423.9e-0712751516
STKc_PRKX_likecd056126.4e-0512751545
PTKc_Tec_likecd050592.6e-0912841521
STKc_SLK_likecd066112.5e-0612841535
STKc_NAK1_likecd069175.7e-0612871537
STKc_PKCcd055702.9e-0712881531
STKc_Nek2cd082174e-0512931517
PKc_MAPKK_Pek1_likecd066210.0001613171533
Arfpfam000250.00039622822
Pkinasepfam000694.4e-3912421520
LRR_TYPsmart003690.00092379401
LRRsmart003700.00092379401
Miropfam084771.3e-06640760
TyrKcsmart002193.9e-1912421520
STYKcsmart002215.8e-3312421525
Pkinase_Tyrpfam077144.2e-1912431520
S_TKcsmart002208.5e-3012521525

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_040674Polymorphismp.ALA1803THRN/A
Swiss-ProtVAR_040677Polymorphismp.ASP1927GLYN/A
dbSNPrs3752321 Polymorphismp.GLU2002LYSN/A
dbSNPrs2924835 Polymorphismp.GLY1938ASPN/A
Swiss-ProtVAR_040675Polymorphismp.LEU1824PHEN/A
dbSNPrs35985016 Polymorphismp.LYS203GLUN/A
dbSNPrs61733308 Polymorphismp.SER1855ALAN/A
Swiss-ProtVAR_040676Polymorphismp.SER1847ASNN/A



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