Results for the protein: Q96QB1

Results for the Protein: Q96QB1

313104315

10395

DLC1

NCBI, UniProt

RHG07_HUMAN RecName: Full=Rho GTPase-activating protein 7; AltName: Full=Deleted in liver cancer 1 protein; Short=DLC-1; AltName: Full=HP protein; AltName: Full=Rho-type GTPase-activating protein 7; AltName: Full=START domain-containing protein 12; Short=StARD12; AltName: Full=StAR-related lipid transfer protein 12

Known Diseases associated with this Protein:
COLORECTAL CANCER, SOMATIC

1

13

1

6

7

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Swiss-Prot Protein: Q96QB1

Identical to: NP_872584

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
RhoGAP_nadrin	cd04386	4e-12	1072	1290
RhoGAP_Graf	cd04374	3.6e-08	1073	1245
RhoGAP_srGAP	cd04383	1.3e-09	1074	1250
RhoGAP_CdGAP	cd04384	4.8e-10	1074	1265
RhoGAP_ARHGAP22_24_2	cd04390	1.8e-08	1074	1284
RhoGAP_FAM13A1a	cd04393	1.1e-12	1074	1254
RhoGAP_ARHGAP18	cd04391	1.1e-23	1075	1295
RhoGAP-ARHGAP11A	cd04394	1.1e-19	1075	1291
RhoGAP_ARHGAP21	cd04395	1.1e-06	1075	1234
RhoGAP_fSAC7_BAG7	cd04396	3.5e-08	1075	1248
RhoGAP_ARHGAP20	cd04402	7.2e-09	1075	1245
RhoGAP_fBEM3	cd04400	1.6e-05	1075	1237
RhoGAP_chimaerin	cd04372	6.7e-08	1076	1284
RhoGAP_p190	cd04373	9.9e-10	1076	1260
RhoGAP_myosin_IX	cd04377	1.8e-10	1076	1279
RhoGAP_GMIP_PARG1	cd04378	3.9e-10	1076	1270
RhoGAP_SYD1	cd04379	2.9e-09	1076	1287
RhoGap_RalBP1	cd04381	6.4e-10	1076	1248
RhoGAP_KIAA1688	cd04389	6.1e-05	1076	1266
RhoGAP_fLRG1	cd04397	2.9e-09	1076	1290
RhoGAP_fRGD1	cd04398	1.1e-11	1076	1249
RhoGAP_Bcr	cd04387	1.3e-06	1076	1279
RhoGAP_ARHGAP27_15_1	cd04403	3.9e-10	1076	1279
RhoGAP-p50rhoGAP	cd04404	9.6e-14	1076	1256
RhoGAP_myosin_IXA	cd04406	1.8e-08	1076	1279
RhoGAP_myosin_IXB	cd04407	7.6e-15	1076	1265
RhoGAP_PARG1	cd04409	2.8e-07	1076	1270
RhoGAP_GMIP	cd04408	3e-07	1076	1270
RhoGAP_ARAP	cd04385	3.8e-12	1077	1250
RhoGAP_ARHGAP6	cd04376	5.4e-15	1083	1290
RhoGAP_ARHGAP19	cd04392	2e-10	1087	1296
RhoGAP	cd00159	1.4e-53	1092	1279
RhoGAP_MgcRacGAP	cd04382	2.2e-05	1097	1251
START_1	cd08876	0.00039	1304	1523
START_STARD8-like	cd08907	1.1e-92	1315	1518
START_STARD12-like	cd08908	2.5e-181	1315	1518
START_STARD13-like	cd08909	1.4e-105	1315	1518
START_STARD4_5_6-lik	cd08867	0.00073	1319	1510
START_STARD10-like	cd08871	7.5e-07	1322	1527
START_RhoGAP	cd08869	2.7e-143	1323	1518
START	cd00177	1.3e-23	1330	1516
RhoGAP	pfam00620	4.5e-55	1092	1242
START	pfam01852	4.3e-70	1323	1522
SAM_2	pfam07647	5.4e-09	448	513
RhoGAP	smart00324	6.2e-55	1089	1280
START	smart00234	1.8e-60	1323	1524

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_059293	Polymorphism	p.ARG27CYS	N/A
dbSNP	rs11203494	Polymorphism	p.ASN255ASP	N/A
Swiss-Prot	VAR_014229	Polymorphism	p.ASN712SER	N/A
dbSNP	rs11203495	Polymorphism	p.GLN254HIS	N/A
dbSNP	rs34591797	Polymorphism	p.GLN320HIS	N/A
Swiss-Prot	VAR_014234	Polymorphism	p.GLU1199VAL	N/A
Swiss-Prot	VAR_014232	Polymorphism	p.HIS998GLN	N/A
dbSNP	rs3816748	Polymorphism	p.LEU81VAL	N/A
Swiss-Prot	VAR_014235	Polymorphism	p.SER1209CYS	N/A
Swiss-Prot	VAR_014231	Polymorphism	p.THR959ALA	N/A
dbSNP	rs3816747	Polymorphism	p.THR260ILE	N/A
Swiss-Prot	VAR_014233	Polymorphism	p.VAL1025ALA	N/A
dbSNP	rs532841	Polymorphism	p.VAL791MET	N/A
OMIM	604258.0001	Disease	p.THR522ALA	COLORECTAL CANCER, SOMATIC

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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