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Results for the Protein: P50281
317373419

MMP14_HUMAN RecName: Full=Matrix metalloproteinase-14; Short=MMP-14; AltName: Full=MMP-X1; AltName: Full=Membrane-type matrix metalloproteinase 1; Short=MT-MMP 1; Short=MTMMP1; AltName: Full=Membrane-type-1 matrix metalloproteinase; Short=MT1-MMP; Short=MT1MMP; Flags: Precursor

Known Diseases associated with this Protein:
  WINCHESTER SYNDROME (1 FAMILY)
1
8
1
3
5
Tips:
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Default View:

PG_binding_1 - pfam01471
ZnMc - smart00235
Peptidase_M10 - pfam00413
ZnMc_MMP - cd04278
ZnMc_MMP_like - cd04268
ZnMc_serralysin_like - cd04277
ZnMc_MMP_like_1 - cd04279
ZnMc - cd00203
HX - cd00094
HX - smart00120
Hemopexin - pfam00045
DUF3377 - pfam11857


Swiss-Prot Protein: P50281
Identical to: NP_004986
   Default View:









Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
ZnMc_MMPcd042782.6e-97118284
ZnMc_serralysin_likecd042772.1e-07121284
ZnMc_MMP_like_1cd042792.3e-12121284
ZnMc_MMP_likecd042681.2e-05121283
ZnMccd002031.1e-15122283
HXcd000942.3e-91316508
PG_binding_1pfam014715.8e-092888
Peptidase_M10pfam004131.2e-95118284
Hemopexinpfam000452.1e-14323366
Hemopexinpfam000451.7e-15368412
Hemopexinpfam000456e-16415461
Hemopexinpfam000454.2e-12463508
ZnMcsmart002351.5e-67115285
HXsmart001209e-11323366
HXsmart001202.8e-13368412
HXsmart001206.7e-16415461
HXsmart001201.6e-10463510
DUF3377pfam118573.2e-42508582

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
dbSNPrs17882219 Polymorphismp.ALA4THRN/A
Swiss-ProtVAR_031267Polymorphismp.ARG431HISN/A
Swiss-ProtVAR_021030Polymorphismp.ARG6LYSN/A
Swiss-ProtVAR_021034Polymorphismp.ARG302TRPN/A
dbSNPrs1042704 Polymorphismp.ASP273ASNN/A
Swiss-ProtVAR_021032Polymorphismp.ILE233VALN/A
Swiss-ProtVAR_021035Polymorphismp.MET355ILEN/A
dbSNPrs1042703 Polymorphismp.PRO8SERN/A
OMIM600754.0001 Diseasep.THR17ARGWINCHESTER SYNDROME (1 family)



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