Results for the protein: Q86YR7

Results for the Protein: Q86YR7

317373423

23101

MCF2L2

NCBI, UniProt

MF2L2_HUMAN RecName: Full=Probable guanine nucleotide exchange factor MCF2L2; AltName: Full=Dbs-related Rho family guanine nucleotide exchange factor; AltName: Full=MCF2-transforming sequence-like protein 2

			0 11 0 0 11

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Default View: SEC14 - cd00170 SEC14 - smart00516 SPEC - cd00176 SPEC - smart00150 RhoGEF - cd00160 RhoGEF - smart00325 RhoGEF - pfam00621 - cd01232 PH_Dbs - cd01227 PH - smart00233 PH - cd00821	Swiss-Prot Protein: Q86YR7 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
SPEC	cd00176	6.5e-10	321	527
RhoGEF	cd00160	6e-30	620	820
	cd01232	6.4e-14	837	955
PH_Dbs	cd01227	4.2e-100	839	971
PH	cd00821	7.6e-07	852	952
RhoGEF	pfam00621	5.2e-21	624	821
SEC14	smart00516	2.4e-13	43	190
SPEC	smart00150	2.4e-12	323	428
RhoGEF	smart00325	9.6e-70	623	821
PH	smart00233	6.3e-12	841	954

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_043593	Polymorphism	p.ARG622HIS	N/A
Swiss-Prot	VAR_043589	Polymorphism	p.ASN277SER	N/A
Swiss-Prot	VAR_043591	Polymorphism	p.GLN378LEU	N/A
Swiss-Prot	VAR_043590	Polymorphism	p.ILE359LEU	N/A
Swiss-Prot	VAR_043597	Polymorphism	p.LEU1039PHE	N/A
Swiss-Prot	VAR_043588	Polymorphism	p.LEU254PRO	N/A
Swiss-Prot	VAR_043596	Polymorphism	p.MET1015THR	N/A
Swiss-Prot	VAR_043594	Polymorphism	p.PHE772LEU	N/A
Swiss-Prot	VAR_043592	Polymorphism	p.PHE589SER	N/A
Swiss-Prot	VAR_043595	Polymorphism	p.THR902ALA	N/A
Swiss-Prot	VAR_043587	Polymorphism	p.THR159MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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