Results for the protein: Q9UKQ2

Results for the Protein: Q9UKQ2

317373485

10863

ADAM28

NCBI, UniProt

ADA28_HUMAN RecName: Full=Disintegrin and metalloproteinase domain-containing protein 28; Short=ADAM 28; AltName: Full=Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; Short=eMDC II; AltName: Full=Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L; Short=MDC-L; Flags: Precursor

			0 14 0 7 7

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: Pep_M12B_propep - pfam01562 ZnMc - cd00203 Reprolysin - pfam01421 ZnMc_ADAMTS_like - cd04273 ZnMc_ADAM_like - cd04267 ZnMc_adamalysin_II_l - cd04269 ZnMc_salivary_gland_ - cd04272 ZnMc_TACE_like - cd04270 ZnMc_ADAM_fungal - cd04271 Disintegrin - pfam00200 DISIN - smart00050 ACR - smart00608 ADAM_CR - pfam08516	Swiss-Prot Protein: Q9UKQ2 Identical to: NP_055080 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
ZnMc_ADAM_like	cd04267	8.7e-39	204	388
ZnMc_adamalysin_II_l	cd04269	2.5e-107	204	397
ZnMc_ADAMTS_like	cd04273	7.6e-15	204	396
ZnMc_salivary_gland_	cd04272	3.8e-07	205	396
ZnMc_TACE_like	cd04270	1.2e-05	209	403
ZnMc_ADAM_fungal	cd04271	5e-05	211	396
Pep_M12B_propep	pfam01562	3.6e-50	5	156
Reprolysin	pfam01421	8.4e-104	204	399
Disintegrin	pfam00200	1.2e-41	416	491
DISIN	smart00050	9.4e-38	416	490
ADAM_CR	pfam08516	1.4e-41	493	600
ACR	smart00608	5.6e-52	493	620

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs35186768	Polymorphism	p.ARG148LEU	N/A
dbSNP	rs9314282	Polymorphism	p.ARG219MET	N/A
dbSNP	rs7001647	Polymorphism	p.ASN493SER	N/A
Swiss-Prot	VAR_057068	Polymorphism	p.GLU226ASP	N/A
Swiss-Prot	VAR_066321	Polymorphism	p.GLY502ASP	N/A
Swiss-Prot	VAR_066318	Polymorphism	p.GLY134GLU	N/A
Swiss-Prot	VAR_066319	Polymorphism	p.GLY450GLU	N/A
Swiss-Prot	VAR_066317	Polymorphism	p.GLY65GLU	N/A
dbSNP	rs34932246	Polymorphism	p.LYS696GLN	N/A
dbSNP	rs7829965	Polymorphism	p.MET684ILE	N/A
Swiss-Prot	VAR_066320	Polymorphism	p.SER482PHE	N/A
dbSNP	rs36041430	Polymorphism	p.THR593LYS	N/A
Swiss-Prot	VAR_057071	Polymorphism	p.THR604PRO	N/A
dbSNP	rs7814768	Polymorphism	p.VAL765MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258