Results for the protein: Q8TEA7

Results for the Protein: Q8TEA7

317373548

93627

TBCK

NCBI, UniProt

TBCK_HUMAN RecName: Full=TBC domain-containing protein kinase-like protein

			0 10 0 0 10

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Swiss-Prot Protein: Q8TEA7

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_Chk	cd05083	0.00018	1	275
PTKc_Btk_Bmx	cd05113	0.00039	1	272
PKc_STE	cd05122	3e-12	1	272
STKc_TAO	cd06607	0.00021	1	310
STKc_TAO2	cd06634	6.6e-06	1	304
STKc_TNIK	cd06637	0.00094	1	273
STKc_SLK	cd06643	0.00063	1	288
STKc_PAK2	cd06655	0.00092	1	295
STKc_CdkB_plant	cd07837	6.9e-06	1	274
STKc_CDKL1_4	cd07847	3.3e-06	1	273
STKc_TEY_MAPK_plant	cd07858	2.6e-06	1	321
STKc_TDY_MAPK_plant	cd07859	7.9e-06	1	318
STKc_CDK2_3	cd07860	0.0001	1	273
STKc_NLK	cd07853	0.00095	1	339
STKc_CDK4	cd07863	2.5e-06	1	273
STKc_PCTAIRE_like	cd07844	0.00025	1	273
PTKc_Abl	cd05052	0.00019	2	273
PTKc_Lck_Blk	cd05067	0.00047	2	276
PTKc_Csk	cd05082	0.00047	2	274
PTKc_Tyk2_rpt2	cd05080	0.00021	2	278
STKc_ASK	cd06624	0.00087	2	273
STKc_myosinIIIA	cd06638	0.00053	2	273
STKc_ERK1_2_like	cd07849	0.00023	2	314
STKc_FA2-like	cd08529	1.8e-05	2	273
SPS1	COG0515	4.2e-23	2	442
PTKc_Hck	cd05073	0.00029	3	276
STKc_MEKK3_like	cd06625	8.4e-08	3	273
STKc_TAO1	cd06635	8.5e-05	3	328
STKc_MAP4K3	cd06645	9.1e-05	3	272
STKc_MAP4K5	cd06646	0.00042	3	272
STKc_MEKK3	cd06651	4.3e-05	3	276
STKc_CDK6	cd07862	6e-05	3	273
PTKc_InsR_like	cd05032	0.00024	4	270
PTKc_ALK_LTK	cd05036	2.7e-05	4	270
STKc_MAPKKK_Byr2_lik	cd06628	3e-05	4	273
STKc_MEKK1	cd06630	7.4e-05	4	274
STKc_Pho85	cd07836	0.00018	4	273
STKc_p38	cd07851	2.8e-06	4	317
STKc_Sty1_Hog1	cd07856	1.7e-05	4	313
STKc_PCTAIRE3	cd07871	0.00016	4	273
STKc_PCTAIRE2	cd07872	6.1e-05	4	293
STKc_PCTAIRE1	cd07873	0.00026	4	285
STKc_CDK1_euk	cd07861	0.00063	4	273
STKc_Nek3	cd08219	0.00015	4	273
STKc_Nek11	cd08222	0.00037	4	273
PTKc	cd00192	1.8e-08	5	272
PTKc_Ack_like	cd05040	2.3e-06	5	269
PTKc_Fes	cd05084	0.00037	5	273
STKc_nPKC_theta_delt	cd05592	0.00032	5	325
STKc_PRKX_like	cd05612	4.8e-05	5	307
STKc_nPKC_theta	cd05619	0.00016	5	319
STKc_OSR1_SPAK	cd06610	6.8e-09	5	273
STKc_CDK1_like	cd07835	9.1e-05	5	273
STKc_CDK5	cd07839	2.3e-06	5	273
STKc_CDK12	cd07864	7.4e-06	5	273
PKc	cd00180	5.1e-36	7	271
PTKc_Jak_rpt2	cd05038	2.7e-07	7	276
STKc_SGK2	cd05603	0.00098	7	307
STKc_nPKC_epsilon	cd05591	0.00033	8	324
STKc_CDK7	cd07841	1.9e-08	8	286
STKc_CDK9	cd07865	0.00038	8	273
STKc_PKB	cd05571	3.4e-05	9	310
PTKc_Fes_like	cd05041	0.00011	10	274
STKc_YSK4	cd06631	2.8e-05	10	273
STKc_MEKK1_plant	cd06632	3.9e-06	10	269
STKc_Nek8	cd08220	3.2e-05	10	273
STKc_PDK1	cd05581	1.8e-09	12	273
STKc_PAK	cd06614	2.4e-07	13	288
STKc_CDK8_like	cd07842	0.00034	13	273
STKc_CDK4_6_like	cd07838	2.5e-07	14	273
STKc_MAPK4_6	cd07854	0.00089	14	313
PTKc_Jak2_Jak3_rpt2	cd05081	3.5e-06	15	273
PKc_MAPKK	cd06605	4.3e-08	15	276
PKc_MKK4	cd06616	6.6e-06	15	294
STKc_PAK_II	cd06648	0.00019	15	250
PKc_MEK	cd06615	4.4e-05	16	294
PTKc_Srm_Brk	cd05148	8.8e-06	19	274
STKc_MAPK	cd07834	2.4e-06	19	311
STKc_MST1_2	cd06612	1.4e-07	20	273
STKc_MAP4K3_like	cd06613	1.1e-07	20	272
STKc_MAPKKK	cd06606	2.4e-13	20	273
STKc_CDK9_like	cd07840	4.8e-08	21	273
STKc_Cdc7_like	cd06627	3.3e-07	22	236
STKc_CDK10	cd07845	1.2e-07	22	286
PKc_MAPKK_Pek1_like	cd06621	1.5e-06	24	280
STKc_BUR1	cd07866	0.00075	24	273
PTKc_Syk_like	cd05060	9.4e-05	25	278
PKc_MKK7	cd06618	5.5e-06	25	296
STKc_MEKK4	cd06626	6.1e-09	25	273
STKc_CDKL	cd07833	6.6e-08	25	273
STKc_CDKL2_3	cd07846	6e-06	25	273
STKc_NAK1_like	cd06917	0.00015	28	254
STKc_MAK_like	cd07830	8.5e-07	28	273
PTKc_Csk_like	cd05039	3.3e-06	29	275
PTKc_Tec_like	cd05059	3.1e-06	30	272
PTKc_EphR	cd05033	0.00031	31	230
STKc_SLK_like	cd06611	5.2e-06	31	282
PKc_MAPKK_Byr1_like	cd06620	8.5e-08	31	281
PTKc_Src_like	cd05034	1e-05	34	276
STKc_AGC	cd05123	1.1e-09	34	273
PKc_MKK3_6	cd06617	1.9e-05	34	292
PKc_MAPKK_plant_like	cd06623	4.4e-06	34	278
STKc_CDC2L1	cd07843	4.3e-05	34	273
STKc_Nek	cd08215	3.8e-09	34	273
STKc_CDK_like	cd07829	6.2e-12	36	273
STKc_Nek2	cd08217	1.1e-06	36	273
STKc_Nek9	cd08221	8.1e-05	36	273
STKc_CMGC	cd05118	5.2e-10	37	273
STKc_PKC	cd05570	7.6e-06	37	317
STKc_MOK	cd07831	6e-07	37	273
STKc_CCRK	cd07832	1.8e-07	37	274
STKc_MAPK15	cd07852	9.8e-07	37	312
STKc_ROCK_NDR_like	cd05573	7.9e-06	40	327
STKc_myosinIII_like	cd06608	0.00041	40	222
STKc_MST3_like	cd06609	4.2e-05	40	287
STKc_Yank1	cd05578	2.8e-07	41	284
STKc_CNK2-like	cd08530	1.9e-05	41	276
STKc_PKA	cd05580	0.00011	42	272
STKc_CRIK	cd05601	0.00049	42	336
STKc_MAPKKK_Bck1_lik	cd06629	0.00027	42	274
STKc_MAST_like	cd05579	9.2e-10	59	278
Cdc25_Acr2p	cd01443	0.00069	768	882
RHOD_Kc	cd01525	2.5e-75	771	882
RHOD	cd00158	1.2e-15	775	881
Pkinase	pfam00069	1.9e-17	12	273
COG5210	COG5210	1.2e-09	287	711
RabGAP-TBC	pfam00566	3.6e-55	469	671
Rhodanese	pfam00581	2e-12	782	883
STYKc	smart00221	5e-22	1	273
TyrKc	smart00219	1.9e-10	1	271
Pkinase_Tyr	pfam07714	8.4e-12	4	272
S_TKc	smart00220	1.1e-27	9	273
KIND	smart00750	4e-05	76	281
TBC	smart00164	3.7e-37	463	653
RHOD	smart00450	9.7e-14	790	886

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041386	Polymorphism	p.ARG692CYS	N/A
Swiss-Prot	VAR_041385	Polymorphism	p.ARG503ILE	N/A
Swiss-Prot	VAR_041380	Polymorphism	p.ARG66LEU	N/A
Swiss-Prot	VAR_041382	Polymorphism	p.ASP265ASN	N/A
Swiss-Prot	VAR_030123	Polymorphism	p.GLN266GLU	N/A
Swiss-Prot	VAR_041381	Polymorphism	p.ILE151MET	N/A
Swiss-Prot	VAR_041387	Polymorphism	p.ILE806VAL	N/A
Swiss-Prot	VAR_030124	Polymorphism	p.LYS489ASN	N/A
Swiss-Prot	VAR_041384	Polymorphism	p.MET471ILE	N/A
Swiss-Prot	VAR_041383	Polymorphism	p.THR425MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258