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Results for the Protein: P21709
317373566

EPHA1_HUMAN RecName: Full=Ephrin type-A receptor 1; Short=hEpha1; AltName: Full=EPH tyrosine kinase; AltName: Full=EPH tyrosine kinase 1; AltName: Full=Erythropoietin-producing hepatoma receptor; AltName: Full=Tyrosine-protein kinase receptor EPH; Flags: Precursor
0
9
0
3
6
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

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Default View:

EPH_lbd - smart00615
Ephrin_lbd - pfam01404
FN3 - smart00060
FN3 - cd00063
fn3 - pfam00041
PTKc_VEGFR - cd05054
PTKc_Kit - cd05104
PTKc_PDGFR_beta - cd05107
PTKc_PDGFR_alpha - cd05105
PTKc_CSF-1R - cd05106
STKc_TAO1 - cd06635
STKc_myosinIIIB - cd06639
STKc_PAK6 - cd06659
PTKc_FGFR1 - cd05098
PTKc_PDGFR - cd05055
STKc_PAK5 - cd06658
PTKc_FGFR2 - cd05101
STKc_TAO3 - cd06633
STKc_PAK - cd06614
STKc_PAK4 - cd06657
STKc_PAK_II - cd06648
STKc_TAO - cd06607
STKc_TAO2 - cd06634
STKc_myosinIIIA - cd06638
PTK_Tyk2_rpt1 - cd05076
PTKc_FGFR3 - cd05100
STKc_PAK3 - cd06656
STKc_MAP4K4_6 - cd06636
STKc_CDK9 - cd07865
STKc_p38 - cd07851
PKc_MKK7 - cd06618
PTKc_FGFR4 - cd05099
STKc_ASK - cd06624
STKc_MAP4K5 - cd06646
PTKc_DDR - cd05051
STKc_STK10_LOK - cd06644
STKc_MAP4K3 - cd06645
PTK_Ryk - cd05043
PKc_MKK4 - cd06616
STKc_CDK12 - cd07864
PTKc_VEGFR2 - cd05103
PTKc_VEGFR3 - cd05102
PTKc_EGFR_like - cd05057
PTKc_HER4 - cd05110
PTK_HER3 - cd05111
PTKc_EGFR - cd05108
PTKc_HER2 - cd05109
PTKc_FAK - cd05056
PTKc_ALK_LTK - cd05036
PTKc_TrkC - cd05094
PTKc_DDR1 - cd05096
PTKc_DDR2 - cd05095
PTKc_TrkA - cd05092
PTKc_Ror2 - cd05091
PTKc_DDR_like - cd05097
PTKc_TrkB - cd05093
STKc_TNIK - cd06637
STKc_TEY_MAPK_plant - cd07858
PTKc_Ror1 - cd05090
STKc_ERK1_2_like - cd07849
PKc_MAPKK_Byr1_like - cd06620
PTKc_Srm_Brk - cd05148
PTKc_Lyn - cd05072
PTKc_Lck_Blk - cd05067
PTKc_Musk - cd05050
PTKc_FGFR - cd05053
PTKc_Csk - cd05082
PTKc_Src_like - cd05034
PTKc_Csk_like - cd05039
PTKc_Ror - cd05048
PTKc_Trk - cd05049
PTK_CCK4 - cd05046
PTKc_InsR - cd05061
PTKc_Abl - cd05052
PTKc_IGF-1R - cd05062
PTKc_Fyn_Yrk - cd05070
PTKc_Hck - cd05073
PTKc_EphR_A2 - cd05063
PTKc_Src - cd05071
PTKc_Yes - cd05069
PTKc_EphR_A10 - cd05064
PTKc_InsR_like - cd05032
PTKc_Frk_like - cd05068
PTKc_Tec_Rlk - cd05114
STKc_myosinIII_like - cd06608
STKc_PFTAIRE2 - cd07870
STKc_SLK - cd06643
STKc_SLK_like - cd06611
PTKc_Btk_Bmx - cd05113
PTKc_EphR_B - cd05065
PTKc_Itk - cd05112
PTKc_Tec_like - cd05059
PTKc_EphR - cd05033
PTKc_EphR_A - cd05066
PTKc_Jak1_rpt2 - cd05079
PTKc_Tie2 - cd05088
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_Chk - cd05083
PTKc_Tyk2_rpt2 - cd05080
PTKc_Jak_rpt2 - cd05038
STKc_MST3 - cd06641
STKc_cPKC - cd05587
STKc_STK25-YSK1 - cd06642
STKc_MST4 - cd06640
SPS1 - COG0515
STKc_MEKK3_like - cd06625
STKc_MEKK3 - cd06651
STKc_MEKK3_like_1 - cd06653
STKc_PCTAIRE1 - cd07873
STKc_MPK1 - cd07857
STKc_Nek4 - cd08223
STKc_PCTAIRE2 - cd07872
STKc_Nek1 - cd08218
STKc_Nek7 - cd08229
STKc_Nek6 - cd08228
STKc_Nek6_Nek7 - cd08224
STKc_CDK1_euk - cd07861
PKc_MEK - cd06615
STKc_CDKL5 - cd07848
STKc_MAPKKK - cd06606
STKc_PRKX_like - cd05612
STKc_MAST - cd05609
PKc_MKK5 - cd06619
PKc_MAPKK_plant_like - cd06623
STKc_Pho85 - cd07836
STKc_CDK7 - cd07841
STKc_MAPKKK_Byr2_lik - cd06628
STKc_YSK4 - cd06631
STKc_MEKK4 - cd06626
STKc_Cdc7_like - cd06627
STKc_PCTAIRE3 - cd07871
STKc_TDY_MAPK_plant - cd07859
STKc_PCTAIRE_like - cd07844
STKc_CDK1_like - cd07835
PTKc_Tie1 - cd05089
PTKc_RET - cd05045
STKc_NLK - cd07853
STKc_MAPK - cd07834
STKc_CDK9_like - cd07840
STKc_Nek5 - cd08225
TyrKc - smart00219
STKc_Nek11 - cd08222
Pkinase - pfam00069
Pkinase_Tyr - pfam07714
PTKc_Tyro3 - cd05074
STKc_PKA - cd05580
PTKc_Axl - cd05075
STYKc - smart00221
PTKc_Axl_like - cd05035
STKc_PKN - cd05589
PKc_MAPKK - cd06605
STKc_CDK6 - cd07862
PKc_MAPKK_PBS2_like - cd06622
PKc_MKK3_6 - cd06617
STKc_Nek3 - cd08219
STKc_Nek - cd08215
STKc_CDK2_3 - cd07860
STKc_CDK4 - cd07863
PK_STRAD - cd08216
STKc_Sty1_Hog1 - cd07856
STKc_CDK10 - cd07845
PKc_STE - cd05122
STKc_PDK1 - cd05581
STKc_CNK2-like - cd08530
STKc_Nek10 - cd08528
STKc_MAK_like - cd07830
STKc_CDK8_like - cd07842
STKc_CDK_like - cd07829
STKc_MST1_2 - cd06612
STKc_Yank1 - cd05578
STKc_CRIK - cd05601
STKc_CDC2L1 - cd07843
STKc_MAPK15 - cd07852
STKc_OSR1_SPAK - cd06610
PKc_MAPKK_Pek1_like - cd06621
STKc_MST3_like - cd06609
STKc_p70S6K - cd05584
STKc_nPKC_theta - cd05619
STKc_SGK2 - cd05603
STKc_nPKC_theta_delt - cd05592
STKc_MAP4K3_like - cd06613
STKc_SGK1 - cd05602
STKc_nPKC_epsilon - cd05591
STKc_FA2-like - cd08529
STKc_BUR1 - cd07866
STKc_CDKL1_4 - cd07847
STKc_CDK4_6_like - cd07838
STKc_MEKK1 - cd06630
PTK_Jak1_rpt1 - cd05077
PTKc_c-ros - cd05044
PTKc_Tie - cd05047
PTKc_Met_Ron - cd05058
PTKc_Syk_like - cd05060
PTKc_Fes_like - cd05041
PTKc_Ack_like - cd05040
PTKc - cd00192
PTK_Jak_rpt1 - cd05037
STKc_RSK_N - cd05582
PTK_Jak2_Jak3_rpt1 - cd05078
PTKc_Fes - cd05084
STKc_PKC - cd05570
STKc_PKB - cd05571
STKc_SGK - cd05575
PTKc_Syk - cd05116
PTKc_Zap-70 - cd05115
PTKc_Fer - cd05085
PTKc_Aatyk2 - cd05086
PTKc_Aatyk1_Aatyk3 - cd05087
STKc_Nek9 - cd08221
STKc_CDKL - cd07833
STKc_NAK1_like - cd06917
STKc_MEKK1_plant - cd06632
STKc_MAPKKK_Bck1_lik - cd06629
STKc_CCRK - cd07832
STKc_Nek8 - cd08220
STKc_Nek2 - cd08217
STKc_CDKL2_3 - cd07846
STKc_CdkB_plant - cd07837
STKc_phototropin_lik - cd05574
STKc_MAPK4_6 - cd07854
STKc_CMGC - cd05118
STKc_cGK_PKG - cd05572
STKc_CDK5 - cd07839
STKc_AGC - cd05123
PTKc_Aatyk - cd05042
PKc - cd00180
STKc_YPK1_like - cd05585
STKc_MAST_like - cd05579
STKc_GRK1 - cd05608
STKc_MOK - cd07831
STKc_GRK7 - cd05607
S_TKc - smart00220
KIND - smart00750
SAM_2 - pfam07647
SAM - smart00454
SAM_1 - pfam00536
- cd00166


Swiss-Prot Protein: P21709
Identical to: NP_005223
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
FN3cd000634.2e-15333442
FN3cd000631.3e-07448535
PTKc_VEGFRcd050546.1e-16515887
PTKc_Kitcd051048.9e-15588884
PTKc_PDGFR_betacd051071.4e-09590885
PTKc_PDGFR_alphacd051052.4e-14592886
PTKc_CSF-1Rcd051061.3e-16597885
STKc_TAO1cd066357.4e-05598924
STKc_myosinIIIBcd066391.6e-05599883
STKc_PAK6cd066591e-06600904
PTKc_FGFR1cd050985e-38601891
PTKc_PDGFRcd050551.9e-17602884
STKc_PAK5cd066580.00016603899
PTKc_FGFR2cd051011.1e-43604895
STKc_TAO3cd066330.0006604924
STKc_PAKcd066142.1e-14605897
STKc_PAK4cd066579.8e-05605901
STKc_PAK_IIcd066481.3e-07606900
STKc_TAOcd066071.3e-05607924
STKc_TAO2cd066343.6e-06607925
PTK_Tyk2_rpt1cd050762.1e-11608881
PTKc_FGFR3cd051003.5e-34608929
STKc_myosinIIIAcd066381.8e-05608882
STKc_MAP4K4_6cd066365.7e-05609882
STKc_PAK3cd066560.00012609907
STKc_p38cd078510.00026609936
STKc_CDK9cd078653.5e-06609896
PKc_MKK7cd066183.4e-08611928
PTKc_FGFR4cd050994e-50612899
STKc_ASKcd066241.6e-07613884
PTKc_DDRcd050515.2e-49614882
STKc_MAP4K3cd066459e-05614881
STKc_MAP4K5cd066460.00091614881
STKc_STK10_LOKcd066442.4e-06614900
PTK_Rykcd050431e-30615883
PKc_MKK4cd066161.4e-06615900
STKc_CDK12cd078641.2e-09615907
PTKc_EGFR_likecd050573.9e-79616894
PTKc_VEGFR3cd051024.3e-19616887
PTKc_VEGFR2cd051031.1e-16616886
PTKc_EGFRcd051086.5e-58616933
PTKc_HER4cd051101.7e-51616911
PTK_HER3cd051111.3e-48616894
PTKc_HER2cd051093.3e-56616894
PTKc_ALK_LTKcd050363.4e-59617882
PTKc_FAKcd050568.5e-90617888
PTKc_InsR_likecd050325.2e-75618882
PTKc_Src_likecd050342.9e-93618883
PTKc_Csk_likecd050392.9e-79618883
PTK_CCK4cd050463.8e-35618882
PTKc_Trkcd050493.3e-66618882
PTKc_Rorcd050485.2e-71618883
PTKc_Muskcd050503.4e-64618882
PTKc_FGFRcd050533.7e-44618885
PTKc_Ablcd050523e-79618884
PTKc_InsRcd050613.3e-52618895
PTKc_IGF-1Rcd050621.4e-54618882
PTKc_EphR_A10cd050646.7e-114618884
PTKc_Lck_Blkcd050672.4e-73618883
PTKc_Frk_likecd050686e-94618883
PTKc_Yescd050691.8e-73618883
PTKc_EphR_A2cd050631.1e-147618884
PTKc_Srccd050717.1e-77618885
PTKc_Fyn_Yrkcd050701.7e-74618883
PTKc_Hckcd050731.6e-74618883
PTKc_Cskcd050825.7e-67618883
PTKc_Ror1cd050904.3e-65618883
PTKc_Ror2cd050912.3e-56618883
PTKc_TrkAcd050927.9e-53618882
PTKc_TrkBcd050931.8e-50618891
PTKc_TrkCcd050943.5e-26618891
PTKc_DDR2cd050955.4e-51618882
PTKc_DDR1cd050966.3e-44618882
PTKc_DDR_likecd050978.3e-48618882
PTKc_Lyncd050727.1e-72618883
PTKc_Srm_Brkcd051485e-73618883
PKc_MAPKK_Byr1_likecd066208.8e-08618894
STKc_TNIKcd066376e-06618882
STKc_ERK1_2_likecd078494.5e-06618937
STKc_TEY_MAPK_plantcd078586.6e-05618958
PTKc_EphRcd050335.6e-210619884
PTKc_Jak_rpt2cd050381.4e-65619884
PTKc_Tec_likecd050591.5e-72619884
PTKc_EphR_Bcd050651.2e-140619884
PTKc_EphR_Acd050669.3e-143619884
PTKc_Jak1_rpt2cd050791.5e-42619884
PTKc_Tyk2_rpt2cd050807.5e-21619885
PTKc_Chkcd050832.4e-70619883
PTKc_Jak2_Jak3_rpt2cd050813.6e-42619884
PTKc_Tie2cd050886.4e-36619898
PTKc_Itkcd051124e-72619881
PTKc_Btk_Bmxcd051137.7e-71619881
PTKc_Tec_Rlkcd051144.1e-72619881
STKc_myosinIII_likecd066081.7e-08619880
STKc_SLK_likecd066117.4e-08619886
STKc_SLKcd066439e-08619898
STKc_PFTAIRE2cd078702.7e-05619918
STKc_cPKCcd055870.00029620934
STKc_MST3cd066411.8e-07620900
STKc_STK25-YSK1cd066423e-08620901
STKc_MST4cd066402.3e-08620904
STKc_MEKK3_likecd066254e-08621882
STKc_MEKK3cd066512.9e-05621883
STKc_MEKK3_like_1cd066530.00015621882
SPS1COG05158.5e-19621974
STKc_MASTcd056090.00021622945
STKc_PRKX_likecd056126.2e-06622914
STKc_MAPKKKcd066063e-17622882
PKc_MEKcd066156.8e-06622902
PKc_MKK5cd066190.00021622929
PKc_MAPKK_plant_likecd066234.4e-11622889
STKc_MEKK4cd066263.2e-07622880
STKc_Cdc7_likecd066271.7e-14622880
STKc_YSK4cd066312.6e-07622880
STKc_MAPKKK_Byr2_likcd066281.6e-12622882
STKc_Pho85cd078367e-07622918
STKc_CDK7cd078411.2e-09622877
STKc_CDKL5cd078480.00093622907
STKc_MPK1cd078570.0002622953
STKc_CDK1_eukcd078615.8e-05622907
STKc_PCTAIRE2cd078720.00022622899
STKc_PCTAIRE1cd078730.00028622927
STKc_Nek4cd082237.5e-07622880
STKc_Nek6_Nek7cd082242.1e-07622885
STKc_Nek1cd082184.6e-05622885
STKc_Nek6cd082288.4e-06622885
STKc_Nek7cd082292.1e-08622885
PTKc_RETcd050454.6e-51623887
PTKc_Tie1cd050891.5e-38623905
STKc_CDK1_likecd078358.5e-07623907
STKc_MAPKcd078341.1e-05623921
STKc_CDK9_likecd078409.9e-09623873
STKc_PCTAIRE_likecd078449.9e-07623907
STKc_NLKcd078537.4e-06623951
STKc_TDY_MAPK_plantcd078591.2e-05623958
STKc_PCTAIRE3cd078710.00014623907
PTKc_Axl_likecd050351.5e-67624884
PTKc_Tyro3cd050743.5e-65624884
PTKc_Axlcd050753.1e-54624884
STKc_PKAcd055800.00016624896
STKc_PKNcd055893.8e-06624931
PKc_MAPKKcd066052.7e-08624885
PKc_MKK3_6cd066173.3e-06624902
PKc_MAPKK_PBS2_likecd066227.6e-07624929
STKc_CDK6cd078624.6e-05624907
STKc_Nek3cd082196.3e-09624882
STKc_Nek11cd082222.9e-09624881
STKc_Nek5cd082257.1e-05624880
PKc_STEcd051225.6e-15625881
STKc_PDK1cd055814e-07625884
STKc_CDK10cd078453.6e-07625905
STKc_Sty1_Hog1cd078560.00015625951
STKc_CDK2_3cd078605.4e-06625907
STKc_CDK4cd078633.1e-05625916
STKc_Nekcd082151.5e-12625889
PK_STRADcd082160.00096625896
STKc_CNK2-likecd085306.7e-06625880
STKc_Nek10cd085280.00011625882
STKc_CRIKcd056010.00041626936
STKc_Yank1cd055788e-06626889
STKc_MST1_2cd066121.9e-10626880
STKc_CDK_likecd078291.6e-10626873
STKc_MAK_likecd078304.3e-09626882
STKc_CDC2L1cd078434.4e-08626873
STKc_CDK8_likecd078426.1e-05626873
STKc_MAPK15cd078523.6e-05626928
STKc_p70S6Kcd055849.7e-05627930
STKc_MST3_likecd066091.3e-09627891
STKc_OSR1_SPAKcd066103.6e-09627882
PKc_MAPKK_Pek1_likecd066212.7e-08627901
PTKccd001923.1e-127628881
PTK_Jak_rpt1cd050377.2e-13628881
PTKc_Ack_likecd050409.8e-66628882
PTKc_Fes_likecd050412.6e-85628882
PTKc_c-roscd050444.6e-67628882
PTKc_Tiecd050471.3e-44628885
PTKc_Met_Roncd050581.5e-63628886
PTKc_Syk_likecd050602.8e-79628885
PTK_Jak1_rpt1cd050771.5e-12628881
PTK_Jak2_Jak3_rpt1cd050786.6e-14628881
PTKc_Fescd050841.8e-78628882
PTKc_Fercd050851.1e-79628882
PTKc_Aatyk2cd050863.2e-20628879
PTKc_Aatyk1_Aatyk3cd050874.6e-23628882
PTKc_Zap-70cd051154.4e-70628885
PTKc_Sykcd051161.9e-62628885
STKc_PKCcd055705.2e-06628931
STKc_PKBcd055718.5e-05628938
STKc_SGKcd055750.00039628931
STKc_RSK_Ncd055821.4e-05628931
STKc_nPKC_epsiloncd055910.00017628932
STKc_nPKC_theta_deltcd055928.9e-05628938
STKc_SGK1cd056020.00099628953
STKc_SGK2cd056030.00033628949
STKc_nPKC_thetacd056192.7e-05628935
STKc_MAP4K3_likecd066135.7e-08628881
STKc_MEKK1cd066301.3e-05628882
STKc_CDK4_6_likecd078384.2e-07628873
STKc_CDKL1_4cd078478.1e-07628913
STKc_BUR1cd078661.7e-07628899
STKc_FA2-likecd085291.6e-08628880
STKc_phototropin_likcd055746.6e-05629892
STKc_MAPKKK_Bck1_likcd066291.2e-09629882
STKc_MEKK1_plantcd066324e-08629880
STKc_NAK1_likecd069171.6e-06629888
STKc_CCRKcd078323e-07629874
STKc_CDKLcd078330.0001629880
STKc_CdkB_plantcd078373.5e-06629881
STKc_CDKL2_3cd078468.4e-07629883
STKc_Nek2cd082177.3e-06629882
STKc_Nek8cd082204e-06629882
STKc_Nek9cd082215.5e-07629885
PKccd001801e-63630880
PTKc_Aatykcd050426.1e-15630879
STKc_CMGCcd051181.5e-12630880
STKc_AGCcd051231.7e-07630879
STKc_cGK_PKGcd055726.1e-07630880
STKc_MAST_likecd055792.3e-06630879
STKc_YPK1_likecd055853.4e-05630927
STKc_GRK7cd056070.0004630910
STKc_GRK1cd056080.00062630899
STKc_MOKcd078319.5e-08630873
STKc_CDK5cd078393.6e-06630896
STKc_MAPK4_6cd078540.00012630935
cd001661e-23912975
Ephrin_lbdpfam014045.9e-10527204
fn3pfam000412.6e-21334431
Pkinasepfam000692.8e-34624880
SAM_1pfam005368.8e-32911975
EPH_lbdsmart006151.1e-9427203
FN3smart000609.3e-12333429
FN3smart000605.7e-06447525
Pkinase_Tyrpfam077141.8e-142624880
TyrKcsmart002191.4e-127624884
STYKcsmart002218.8e-52624882
S_TKcsmart002201.9e-38634884
KINDsmart007502e-05708890
SAM_2pfam076478.3e-17910975
SAMsmart004541.3e-19910976

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_042117Polymorphismp.ALA585THRN/A
Swiss-ProtVAR_042115Polymorphismp.ARG351CYSN/A
Swiss-ProtVAR_028266Polymorphismp.ARG492GLNN/A
Swiss-ProtVAR_042116Polymorphismp.ARG575GLNN/A
Swiss-ProtVAR_042119Polymorphismp.GLU703LYSN/A
dbSNPrs6967117 Polymorphismp.MET900VALN/A
dbSNPrs34372369 Polymorphismp.PRO697LEUN/A
Swiss-ProtVAR_042120Polymorphismp.SER807ARGN/A
dbSNPrs4725617 Polymorphismp.VAL160ALAN/A



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