Results for the protein: P53355

Results for the Protein: P53355

317373595

1612

DAPK1

NCBI, UniProt

DAPK1_HUMAN RecName: Full=Death-associated protein kinase 1; Short=DAP kinase 1

			0 19 0 0 19

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Swiss-Prot Protein: P53355

Identical to: NP_004929

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_Tie2	cd05088	1.1e-05	1	306
PTKc_HER2	cd05109	0.00017	1	287
PTK_HER3	cd05111	3.8e-05	1	267
STKc_ROCK	cd05596	8.7e-06	1	329
STKc_TAO	cd06607	7.4e-08	1	310
PKc_MKK7	cd06618	2.4e-07	1	302
STKc_TAO3	cd06633	7.2e-05	1	302
STKc_TAO2	cd06634	5.9e-07	1	303
STKc_TAO1	cd06635	1.5e-06	1	302
STKc_myosinIIIA	cd06638	7.8e-09	1	275
STKc_myosinIIIB	cd06639	5.5e-08	1	276
STKc_STK10_LOK	cd06644	1.9e-10	1	295
STKc_PAK_I	cd06647	8e-11	1	296
STKc_PAK1	cd06654	1.1e-08	1	299
STKc_PAK3	cd06656	2.5e-09	1	310
STKc_PAK2	cd06655	8.8e-09	1	302
STKc_CDK9	cd07865	2.3e-11	1	275
STKc_p38alpha_MAPK14	cd07877	2.4e-08	1	309
PTKc_TrkB	cd05093	0.00036	2	294
PTKc_TrkA	cd05092	1.3e-05	2	286
STKc_ROCK2	cd05621	3.5e-06	2	332
STKc_ROCK1	cd05622	0.00015	2	327
STKc_PAK	cd06614	1.4e-17	2	288
STKc_MAP4K5	cd06646	1.1e-09	2	274
STKc_PAK_II	cd06648	8.7e-13	2	288
STKc_PAK5	cd06658	2.4e-08	2	289
STKc_PAK6	cd06659	1.3e-15	2	303
STKc_PAK4	cd06657	1.2e-08	2	291
STKc_Sty1_Hog1	cd07856	1.9e-09	2	303
STKc_JNK3	cd07874	4.2e-06	2	350
STKc_JNK2	cd07876	1.2e-06	2	315
STKc_GRK4_like	cd05605	1.7e-25	3	301
STKc_GRK6	cd05630	2.4e-19	3	300
STKc_GRK5	cd05632	1.6e-19	3	294
STKc_JNK	cd07850	6.1e-08	3	313
STKc_p38	cd07851	2.8e-11	3	317
STKc_JNK1	cd07875	4e-05	3	306
STKc_p38gamma_MAPK12	cd07880	7.3e-09	3	313
STKc_p38beta_MAPK11	cd07878	1.3e-07	3	307
PTKc_InsR_like	cd05032	7.7e-06	4	272
PTKc_Jak_rpt2	cd05038	4e-08	4	274
PKc_MKK4	cd06616	3e-05	4	291
STKc_MAP4K3	cd06645	4.1e-10	4	274
STKc_CDK12	cd07864	1.2e-11	4	275
STKc_BUR1	cd07866	2.4e-11	4	275
STKc_p38delta_MAPK13	cd07879	5.4e-05	4	316
PTKc_FGFR4	cd05099	5.8e-05	5	302
PTKc_FGFR2	cd05101	0.00057	5	271
STKc_CDK10	cd07845	2.8e-11	5	282
PTKc_ALK_LTK	cd05036	4.5e-06	6	257
PTKc_FAK	cd05056	4.5e-08	6	282
STKc_ASK	cd06624	1.2e-18	6	275
STKc_TNIK	cd06637	1.6e-07	6	275
PTKc_Musk	cd05050	3.3e-07	7	272
PTKc_InsR	cd05061	0.00016	7	286
PTKc_IGF-1R	cd05062	0.00073	7	272
PTKc_EphR_A10	cd05064	0.00092	7	274
PTKc_Fyn_Yrk	cd05070	1.4e-05	7	273
PTKc_Src	cd05071	5.5e-05	7	275
PTKc_Lyn	cd05072	1.5e-07	7	273
PTKc_Abl	cd05052	3.4e-06	7	281
PTKc_Hck	cd05073	1.6e-07	7	273
PTKc_Yes	cd05069	3.4e-06	7	273
PTKc_Ror1	cd05090	3.8e-06	7	267
PTKc_Ror2	cd05091	5.7e-06	7	267
PTKc_Lck_Blk	cd05067	1.4e-05	7	296
PTKc_EphR_A2	cd05063	0.0001	7	275
PTKc_Frk_like	cd05068	8.9e-11	7	277
PTKc_DDR2	cd05095	8.2e-05	7	272
PTKc_DDR_like	cd05097	0.00011	7	276
STKc_SLK_like	cd06611	1.2e-12	7	290
STKc_MAP4K4_6	cd06636	4.8e-05	7	275
STKc_SLK	cd06643	3e-12	7	290
PKc_MEK2	cd06649	2.9e-06	7	359
PKc_MEK1	cd06650	4.9e-05	7	353
STKc_ERK1_2_like	cd07849	4.6e-11	7	310
STKc_MAPK15	cd07852	1.1e-11	7	309
STKc_ERK5	cd07855	2.5e-12	7	308
STKc_myosinIII_like	cd06608	5.1e-13	8	275
STKc_MST4	cd06640	3.5e-08	8	306
STKc_MST3	cd06641	1.3e-08	8	306
STKc_STK25-YSK1	cd06642	1e-09	8	306
STKc_CDC2L1	cd07843	2.1e-11	8	275
STKc_PCTAIRE_like	cd07844	1e-14	8	310
STKc_TEY_MAPK_plant	cd07858	3.8e-12	8	318
STKc_PFTAIRE2	cd07870	3.3e-07	8	275
PTKc_EphR	cd05033	6.4e-06	9	252
PTKc_EphR_B	cd05065	3.1e-06	9	275
PTKc_EphR_A	cd05066	0.00011	9	271
PTKc_Btk_Bmx	cd05113	2.2e-08	9	274
STKc_MST1_2	cd06612	2.4e-16	9	275
STKc_MAP4K3_like	cd06613	1.1e-13	9	274
PTKc_Jak1_rpt2	cd05079	1.8e-05	10	275
STKc_MST3_like	cd06609	2.7e-13	10	297
PKc_MAPKK_Byr1_like	cd06620	6.2e-07	10	297
STKc_MEKK2	cd06652	3.7e-08	10	276
STKc_MEKK3_like_1	cd06653	4.8e-10	10	275
STKc_PFTAIRE1	cd07869	9.8e-07	10	289
SPS1	COG0515	3.4e-61	10	439
PTKc_Chk	cd05083	0.00026	11	273
PTKc_Itk	cd05112	1e-07	11	271
STKc_ROCK_NDR_like	cd05573	6.2e-14	11	325
STKc_PKA	cd05580	9.4e-18	11	302
STKc_PDK1	cd05581	1.6e-31	11	275
STKc_NDR_like	cd05599	1.1e-07	11	300
STKc_CRIK	cd05601	5e-12	11	323
STKc_DMPK_like	cd05597	3.6e-09	11	335
STKc_PRKX_like	cd05612	3.1e-25	11	297
STKc_LATS	cd05598	3.4e-08	11	323
STKc_MAST	cd05609	1.7e-18	11	324
STKc_MRCK_beta	cd05624	2.1e-07	11	336
STKc_MRCK_alpha	cd05623	8.4e-08	11	337
STKc_LATS1	cd05625	4.3e-06	11	341
STKc_LATS2	cd05626	0.00017	11	352
STKc_NDR2	cd05627	3.5e-07	11	353
STKc_NDR1	cd05628	1.7e-08	11	338
STKc_NDR_like_fungal	cd05629	2.7e-06	11	354
PKc_MAPKK	cd06605	3.2e-10	11	280
STKc_OSR1_SPAK	cd06610	5.4e-13	11	275
PKc_MEK	cd06615	6.6e-09	11	292
PKc_MKK5	cd06619	0.0002	11	303
PKc_MAPKK_PBS2_like	cd06622	6.8e-09	11	304
PKc_MAPKK_plant_like	cd06623	2.3e-17	11	282
PKc_MKK3_6	cd06617	6.2e-07	11	294
STKc_NAK1_like	cd06917	3e-09	11	292
STKc_CDKL	cd07833	4.2e-12	11	275
STKc_CdkB_plant	cd07837	2e-12	11	276
STKc_CDK8_like	cd07842	5.4e-11	11	275
STKc_CDKL2_3	cd07846	4.3e-10	11	275
STKc_CDKL1_4	cd07847	3.9e-19	11	310
STKc_PCTAIRE3	cd07871	4e-09	11	275
STKc_PCTAIRE2	cd07872	2.9e-08	11	294
STKc_PCTAIRE1	cd07873	2e-07	11	286
STKc_CDKL5	cd07848	1.5e-06	11	275
STKc_CDK6	cd07862	1.8e-06	11	296
STKc_Nek6_Nek7	cd08224	9.7e-09	11	282
STKc_Nek6	cd08228	1.8e-06	11	284
STKc_Nek7	cd08229	5.5e-08	11	273
PTKc_Tyk2_rpt2	cd05080	1e-05	12	272
PKc_STE	cd05122	9.9e-35	12	274
PTKc_Tie1	cd05089	8.2e-06	12	305
STKc_MSK_N	cd05583	7e-25	12	294
STKc_MSK1_N	cd05613	2.1e-25	12	294
STKc_MSK2_N	cd05614	3.2e-15	12	346
STKc_cPKC_alpha	cd05615	2.2e-10	12	324
STKc_GRK4	cd05631	1.9e-17	12	302
STKc_MAPKKK	cd06606	4.2e-33	12	275
STKc_MAPKKK_Byr2_lik	cd06628	9.1e-25	12	275
STKc_MEKK1	cd06630	1.2e-10	12	276
STKc_YSK4	cd06631	8.6e-13	12	275
STKc_MEKK3	cd06651	7.3e-12	12	277
STKc_Cdc7_like	cd06627	2.1e-18	12	275
STKc_CCRK	cd07832	5.2e-14	12	276
STKc_Pho85	cd07836	3.8e-16	12	275
STKc_CDK5	cd07839	5.5e-09	12	275
STKc_CDK7	cd07841	5.5e-18	12	286
STKc_MAPK	cd07834	8.6e-14	12	308
STKc_CDK2_3	cd07860	8.6e-12	12	275
STKc_TDY_MAPK_plant	cd07859	1.2e-09	12	322
STKc_CDK1_euk	cd07861	5.4e-17	12	275
STKc_CDK4	cd07863	9.6e-09	12	275
STKc_CDC2L6	cd07867	7.2e-07	12	275
STKc_CDK8	cd07868	2.9e-06	12	275
STKc_MPK1	cd07857	5.9e-09	12	304
STKc_NLK	cd07853	1.7e-09	12	348
STKc_Nek	cd08215	1.9e-21	12	275
STKc_Nek2	cd08217	4.8e-14	12	275
STKc_Nek1	cd08218	1e-16	12	275
STKc_Nek8	cd08220	9.3e-10	12	275
STKc_Nek9	cd08221	1.2e-10	12	275
STKc_Nek11	cd08222	1.6e-07	12	275
STKc_Nek5	cd08225	4.6e-09	12	275
STKc_Nek4	cd08223	1.7e-11	12	275
STKc_Nek3	cd08219	4.7e-11	12	275
STKc_CNK2-like	cd08530	3.7e-11	12	275
STKc_Nek10	cd08528	2.6e-10	12	268
PTKc_Axl_like	cd05035	0.00013	13	278
PTKc_Tyro3	cd05074	7.7e-05	13	274
PTKc_Tec_Rlk	cd05114	9.4e-07	13	274
STKc_CMGC	cd05118	2.4e-18	13	275
PTKc_Srm_Brk	cd05148	7.5e-09	13	273
STKc_cPKC	cd05587	1.1e-13	13	352
STKc_PKN	cd05589	2.4e-10	13	328
STKc_p70S6K	cd05584	1e-17	13	339
STKc_cPKC_beta	cd05616	4.5e-09	13	329
STKc_MEKK3_like	cd06625	3.4e-15	13	275
STKc_CDK_like	cd07829	3.5e-21	13	275
STKc_MAK_like	cd07830	1.8e-14	13	275
STKc_MOK	cd07831	2.8e-11	13	275
STKc_CDK1_like	cd07835	3.8e-15	13	275
STKc_CDK9_like	cd07840	1.9e-16	13	275
STKc_CDK4_6_like	cd07838	9.2e-13	13	275
STKc_MAPK4_6	cd07854	4.9e-07	13	306
STKc_FA2-like	cd08529	2.6e-11	13	275
PKc_MAPKK_Pek1_like	cd06621	1.2e-09	14	301
PTKc_Src_like	cd05034	2.8e-09	16	273
PTKc_RET	cd05045	0.00027	16	259
PTKc_Tec_like	cd05059	4.3e-08	16	248
STKc_MEKK4	cd06626	1.1e-15	16	275
STKc_MAPKKK_Bck1_lik	cd06629	1.9e-10	16	275
STKc_MEKK1_plant	cd06632	6.9e-14	16	275
PTKc	cd00192	1.2e-09	17	271
PTKc_Ack_like	cd05040	1.1e-09	17	272
PTKc_Fes_like	cd05041	4.2e-11	17	272
PTKc_Aatyk	cd05042	0.00065	17	258
PTKc_Tie	cd05047	4.4e-05	17	277
PTKc_Ror	cd05048	1.4e-07	17	258
PTKc_Trk	cd05049	2.1e-06	17	272
PTKc_Met_Ron	cd05058	0.00046	17	294
PTKc_Syk_like	cd05060	3.2e-07	17	253
PTK_Jak1_rpt1	cd05077	4.9e-05	17	274
PTKc_Jak2_Jak3_rpt2	cd05081	3.7e-07	17	297
PTKc_Fes	cd05084	5.2e-08	17	272
PTKc_Fer	cd05085	6.3e-08	17	272
PTK_Jak2_Jak3_rpt1	cd05078	0.00025	17	252
PTKc_Syk	cd05116	7.3e-07	17	275
STKc_PKB	cd05571	1.7e-20	17	342
STKc_phototropin_lik	cd05574	3.4e-16	17	294
STKc_RSK_N	cd05582	2.5e-20	17	344
STKc_aPKC	cd05588	2.6e-10	17	353
STKc_nPKC_eta	cd05590	7e-08	17	345
STKc_nPKC_epsilon	cd05591	2.5e-08	17	364
STKc_nPKC_theta_delt	cd05592	4.2e-15	17	353
STKc_PKB_gamma	cd05593	6.4e-11	17	334
STKc_PKB_beta	cd05595	9.2e-11	17	342
STKc_PKB_alpha	cd05594	2.5e-12	17	334
STKc_SGK1	cd05602	1e-08	17	330
STKc_SGK	cd05575	2.1e-10	17	344
STKc_SGK2	cd05603	3.4e-10	17	329
STKc_SGK3	cd05604	1.3e-08	17	346
STKc_nPKC_theta	cd05619	1.9e-11	17	333
STKc_nPKC_delta	cd05620	3e-07	17	354
PTKc_Zap-70	cd05115	2.1e-07	18	275
STKc_Rim15_like	cd05611	2.1e-06	18	281
PKc	cd00180	1.1e-77	19	273
PTKc_c-ros	cd05044	4.5e-06	19	272
STKc_AGC	cd05123	5e-32	19	275
STKc_PKC	cd05570	4e-14	19	302
STKc_cGK_PKG	cd05572	2e-19	19	282
STKc_GRK	cd05577	1.8e-13	19	278
STKc_MAST_like	cd05579	1.1e-19	19	280
STKc_YPK1_like	cd05585	5.6e-14	19	327
STKc_Sck1_like	cd05586	3.3e-09	19	381
STKc_beta_ARK	cd05606	1.3e-09	19	295
STKc_GRK7	cd05607	1.7e-13	19	295
STKc_GRK1	cd05608	1.4e-20	19	299
STKc_aPKC_zeta	cd05617	7.1e-09	19	353
STKc_aPKC_iota	cd05618	2.8e-07	19	353
STKc_GRK3	cd05633	2.7e-08	19	296
STKc_Yank1	cd05578	3.4e-15	20	275
STKc_Sid2p_Dbf2p	cd05600	1.2e-06	22	306
Arp	COG0666	2.1e-32	341	667
ANK	cd00204	2.5e-41	373	498
ANK	cd00204	4.2e-45	505	630
Death_UNC5-like	cd08781	0.00011	1305	1393
Death_DAPK1	cd08782	1.9e-55	1308	1393
Death	cd01670	5e-14	1309	1393
Death_NFkB-like	cd08310	0.00052	1309	1393
Death_p75NR	cd08311	6.3e-06	1309	1393
Death_MyD88	cd08312	2e-05	1309	1393
Pkinase	pfam00069	6.4e-88	13	275
Ank	pfam00023	1.8e-05	378	410
Ank	pfam00023	1.6e-08	444	476
Ank	pfam00023	7e-08	477	509
Ank	pfam00023	4.8e-09	510	542
Ank	pfam00023	5.2e-07	543	575
Ank	pfam00023	5.9e-07	576	608
Ank	pfam00023	6e-07	609	641
Death	pfam00531	2.3e-19	1311	1396
Pkinase_Tyr	pfam07714	4.4e-14	13	270
TyrKc	smart00219	1.2e-12	13	273
STYKc	smart00221	1e-88	13	275
S_TKc	smart00220	1.6e-98	23	275
ANK	smart00248	2.6e-05	444	473
ANK	smart00248	3.4e-06	477	506
ANK	smart00248	1.1e-05	510	539
ANK	smart00248	0.00085	543	572
ANK	smart00248	1.2e-05	576	605
ANK	smart00248	4.4e-05	609	638
DEATH	smart00005	1.9e-25	1306	1395

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040420	Polymorphism	p.ALA461SER	N/A
Swiss-Prot	VAR_040431	Polymorphism	p.ARG1010CYS	N/A
Swiss-Prot	VAR_040424	Polymorphism	p.ARG977TRP	N/A
Swiss-Prot	VAR_040427	Polymorphism	p.ASP994GLU	N/A
Swiss-Prot	VAR_040429	Polymorphism	p.ASP1007TYR	N/A
Swiss-Prot	VAR_040422	Polymorphism	p.CYS540TYR	N/A
Swiss-Prot	VAR_040428	Polymorphism	p.GLU1005GLN	N/A
Swiss-Prot	VAR_040435	Polymorphism	p.GLY1405VAL	N/A
Swiss-Prot	VAR_060694	Polymorphism	p.ILE622MET	N/A
Swiss-Prot	VAR_040430	Polymorphism	p.LEU1008PRO	N/A
Swiss-Prot	VAR_040425	Polymorphism	p.LYS978ASN	N/A
Swiss-Prot	VAR_040433	Polymorphism	p.MET1272ILE	N/A
Swiss-Prot	VAR_040423	Polymorphism	p.MET941THR	N/A
Swiss-Prot	VAR_060693	Polymorphism	p.PRO591LEU	N/A
Swiss-Prot	VAR_040421	Polymorphism	p.SER519ALA	N/A
Swiss-Prot	VAR_040434	Polymorphism	p.SER1346ASN	N/A
Swiss-Prot	VAR_040432	Polymorphism	p.THR1018ALA	N/A
Swiss-Prot	VAR_040426	Polymorphism	p.TYR993CYS	N/A
Swiss-Prot	VAR_033235	Polymorphism	p.VAL416ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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