Results for the protein: NP

Results for the Protein: NP_001191818

325910904

217

ALDH2

NCBI

aldehyde dehydrogenase, mitochondrial isoform 2 precursor [Homo sapiens]

Known Diseases associated with this Protein:
  ALCOHOL DEPENDENCE, PROTECTION AGAINST, INCLUDED;;
  ALCOHOL SENSITIVITY, ACUTE
  HANGOVER, SUSCEPTIBILITY TO, INCLUDED;;|

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Tips:

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RefSeq Protein: NP_001191818

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
ALDH_RL0313	cd07148	4.9e-15	2	463
ALDH_KGSADH-like	cd07084	2.8e-09	13	463
ALDH_PutA-P5CDH-RocA	cd07124	4.6e-43	15	465
ALDH_P5CDH	cd07083	2.2e-37	19	465
ALDH_F16	cd07111	7e-129	26	463
ALDH_F1AB_F2_RALDH1	cd07141		31	464
ALDH_CALDH_CalB	cd07133	4e-18	32	463
ALDH_F1-2_Ald2-like	cd07091		34	463
ALDH_F1L_FTFDH	cd07140	8.5e-150	34	465
ALDH_F2BC	cd07142	1.6e-270	34	463
ALDH_F11_NP-GAPDH	cd07082	1.3e-32	36	464
ALDH_F6_MMSDH	cd07085	9.3e-30	37	465
ALDH_KGSADH-YcbD	cd07097	7.6e-89	37	463
ALDH_ACDHII-AcoD	cd07116	5.8e-121	37	465
PutA	COG1012	5.7e-194	37	468
ALDH_StaphAldA1	cd07117	9.1e-149	38	465
ALDH_ACDHII_AcoD-lik	cd07559	1.9e-160	38	465
ALDH_F7_AASADH-like	cd07086	1.6e-48	39	463
ALDH_F7_AASADH	cd07130	4e-19	39	412
ALDH_AldH-CAJ73105	cd07131	1.3e-78	39	466
ALDH_CddD_SSP0762	cd07138	1.7e-111	39	463
ALDH_AldA-Rv0768	cd07139	4.1e-106	39	463
ALDH_ALD2-YMR170C	cd07144	9.5e-209	39	465
ALDH_AldA_AN0554	cd07143	3.5e-232	39	465
ALDH_LactADH-AldA	cd07088	1.3e-94	40	463
ALDH_PADH_NahF	cd07113	1.2e-84	40	465
ALDH_BADH-GbsA	cd07119	5.3e-167	40	461
ALDH_F12_P5CDH	cd07126	1.3e-05	40	451
ALDH_MaoC-N	cd07128	3e-06	40	457
ALDH_HBenzADH	cd07151	1.2e-45	43	465
ALDH_SaliADH	cd07105	2.2e-46	44	463
ALDH_F3FHI	cd07137	8.7e-14	45	463
ALDH_BenzADH-like	cd07104	1.3e-90	47	463
ALDH-SF	cd06534	5.9e-203	48	463
ALDH	cd07078	6.1e-214	48	463
ALDH_GABALDH-PuuC	cd07112	4.5e-168	51	463
ALDH_AlkH-like	cd07134	2.5e-21	51	463
ALDH_F21_LactADH-lik	cd07094	1.8e-72	54	463
ALDH_LactADH_F420-Bi	cd07145	3.2e-79	54	463
ALDH_PhpJ	cd07146	1.7e-39	54	463
ALDH_F21_RNP123	cd07147	7.8e-32	54	463
ALDH_y4uC	cd07149	1.6e-63	54	463
ALDH_VaniDH_like	cd07150	4.1e-97	54	463
ALDH_F9_TMBADH	cd07090	3.1e-146	56	466
ALDH_ABALDH-YdcW	cd07092	2.1e-117	56	463
ALDH_F8_HMSADH	cd07093	1.7e-150	56	463
ALDH_F5_SSADH_GabD	cd07103	1.7e-105	56	463
ALDH_PhdK-like	cd07107	9e-99	56	465
ALDH_MGR_2402	cd07108	8.4e-94	56	463
ALDH_AldA-AAD23400	cd07106	2.2e-84	56	463
ALDH_AAS00426	cd07109	1e-132	56	463
ALDH_HMSADH_HapE	cd07115	5.1e-199	56	465
ALDH_DhaS	cd07114	1.8e-159	56	463
ALDH_PsfA-ACA09737	cd07120	6.3e-74	56	463
ALDH_F10_BADH	cd07110	6.9e-135	56	463
ALDH_CddD-AldA-like	cd07089	5.1e-120	56	463
ALDH_F14-YMR110C	cd07135	3.6e-18	56	463
ALDH_F15-22	cd07098	1.3e-30	57	465
ALDH_DDALDH	cd07099	2.4e-52	57	463
ALDH_EDX86601	cd07102	1.3e-45	57	463
ALDH_SSADH2_GabD2	cd07101	2.8e-29	57	463
ALDH_SNDH	cd07118	1.1e-107	59	463
ALDH_BenzADH	cd07152	3e-46	62	463
ALDH_F3-13-14_CALDH-	cd07087	1.6e-18	63	463
ALDH_F4-17_P5CDH	cd07123	6.3e-11	63	443
ALDH_SSADH1_GabD1	cd07100	1.4e-44	64	463
ALDH_F3AB	cd07132	6.9e-14	72	456
ALDH_YwdH-P39616	cd07136	1.1e-14	72	464
ALDH_SGSD_AstD	cd07095	9e-18	94	445
COG4230	COG4230	1.2e-06	2	470
Aldedh	pfam00171	7.8e-209	45	461

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs671	Polymorphism	p.GLU457LYS	N/A
OMIM	100650.0001	Disease	p.GLU457LYS	ALCOHOL SENSITIVITY, ACUTE\|\|ALCOHOL DEPENDENCE, PROTECTION AGAINST, INCLUDED;;\|\|HANGOVER, SUSCEPTIBILITY TO, INCLUDED;;\|

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258