Home News About DMDM Database Statistics Research Publications Contact  

Results for the Protein: Q7Z406
327478526

MYH14_HUMAN RecName: Full=Myosin-14; AltName: Full=Myosin heavy chain 14; AltName: Full=Myosin heavy chain, non-muscle IIc; AltName: Full=Non-muscle myosin heavy chain IIc; Short=NMHC II-C

Known Diseases associated with this Protein:
  DEAFNESS, AUTOSOMAL DOMINANT 4
  DEAFNESS, AUTOSOMAL DOMINANT, 4A (DFNA4A)
  PERIPHERAL NEUROPATHY, MYOPATHY, HOARSENESS, AND HEARING LOSS
  PERIPHERAL NEUROPATHY, MYOPATHY, HOARSENESS, AND HEARING LOSS (PNMHH)
11
6
6
2
9
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

COG5022 - COG5022
Myosin_N - pfam02736
MYSc_type_IX - cd01385
MYSc - smart00242
MYSc_type_VIII - cd01383
MYSc_type_II - cd01377
MYSc_type_VI - cd01382
MYSc_type_XV - cd01387
MYSc_type_XI - cd01384
MYSc_type_XVIII - cd01386
MYSc_type_III - cd01379
MYSc_type_VII - cd01381
MYSc - cd00124
MYSc_type_V - cd01380
Myosin_head - pfam00063
MYSc_type_I - cd01378
Motor_domain - cd01363
IQ - smart00015
IQ - pfam00612
Myosin_tail_1 - pfam01576


Swiss-Prot Protein: Q7Z406
Identical to: NP_079005
   Default View:


















Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
MYSc_type_IXcd013855.7e-7499803
MYSc_type_VIIIcd013831.5e-159100799
MYSc_type_IIcd01377101799
MYSc_type_VIcd013821e-95102802
MYSc_type_XVcd013877.6e-156105799
MYSc_type_XIcd013841.6e-195105804
MYSccd001244.1e-280106799
MYSc_type_Vcd013803.1e-210106799
MYSc_type_VIIcd013811.5e-188106799
MYSc_type_IIIcd013795.1e-71106822
MYSc_type_XVIIIcd013861.5e-39106799
MYSc_type_Icd013781.2e-183108799
Motor_domaincd013631e-102141698
COG5022COG50222.7e-304351598
Myosin_Npfam027361.4e-065395
Myosin_headpfam00063107788
IQpfam006120.0002804824
Myosin_tail_1pfam015761.9e-18110901947
MYScsmart00242100800
IQsmart000151.8e-05802824

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
dbSNPrs11669191 Polymorphismp.ALA1209GLUN/A
Swiss-ProtVAR_066339Polymorphismp.ALA1154VALN/A
Swiss-ProtVAR_066338Diseasep.ARG933LEUPeripheral neuropathy, myopathy, hoarseness, and hearing loss (PNMHH)
Swiss-ProtVAR_022868Diseasep.ARG726SERDeafness, autosomal dominant, 4A (DFNA4A)
Swiss-ProtVAR_022870Polymorphismp.ASN1559SERN/A
Swiss-ProtVAR_022867Diseasep.GLY376CYSDeafness, autosomal dominant, 4A (DFNA4A)
Swiss-ProtVAR_022866Polymorphismp.ILE266VALN/A
Swiss-ProtVAR_022869Diseasep.LEU976PHEDeafness, autosomal dominant, 4A (DFNA4A)
dbSNPrs34498817 Polymorphismp.PRO334ALAN/A
Swiss-ProtVAR_037302Diseasep.SER120LEUDeafness, autosomal dominant, 4A (DFNA4A)
Swiss-ProtVAR_056178Polymorphismp.VAL1540ILEN/A
OMIM608568.0006 Diseasep.ARG900LEUPERIPHERAL NEUROPATHY, MYOPATHY, HOARSENESS, AND HEARING LOSS
OMIM608568.0003 Diseasep.ARG685SERDEAFNESS, AUTOSOMAL DOMINANT 4
OMIM608568.0004 Diseasep.GLY368CYSDEAFNESS, AUTOSOMAL DOMINANT 4
OMIM608568.0002 Diseasep.LEU935PHEDEAFNESS, AUTOSOMAL DOMINANT 4
OMIM608568.0005 Diseasep.SER120LEUDEAFNESS, AUTOSOMAL DOMINANT 4
OMIM608568.0001 Diseasep.SER7TERDEAFNESS, AUTOSOMAL DOMINANT 4



   |   1000 Hilltop Circle, Baltimore, MD 21250   |   Department of Biological Sciences   |   Phone: 410-455-2258