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Results for the Protein: Q76MJ5
327478597

ERN2_HUMAN RecName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2; AltName: Full=Endoplasmic reticulum-to-nucleus signaling 2; AltName: Full=Inositol-requiring protein 2; Short=hIRE2p; AltName: Full=Ire1-beta; Short=IRE1b; Includes: RecName: Full=Serine/threonine-protein kinase; Includes: RecName: Full=Endoribonuclease; Flags: Precursor
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Default View:

PQQ - smart00564
STKc_myosinIIIB - cd06639
STKc_TAO1 - cd06635
STKc_JNK2 - cd07876
STKc_TAO3 - cd06633
STKc_MAP4K4_6 - cd06636
STKc_JNK - cd07850
STKc_p38 - cd07851
STKc_TNIK - cd06637
STKc_PAK3 - cd06656
STKc_PAK2 - cd06655
STKc_PAK_II - cd06648
STKc_PAK_I - cd06647
STKc_PAK1 - cd06654
STKc_MST3 - cd06641
STKc_MST4 - cd06640
STKc_TAO - cd06607
STKc_TAO2 - cd06634
PKc_MAPKK_Byr1_like - cd06620
STKc_PAK - cd06614
PTKc_Jak_rpt2 - cd05038
STKc_Nek1 - cd08218
STKc_CDK9 - cd07865
STKc_PAK6 - cd06659
STKc_MAPKKK_Byr2_lik - cd06628
STKc_PAK5 - cd06658
STKc_PAK4 - cd06657
STKc_MAP4K5 - cd06646
PK_STRAD - cd08216
STKc_ASK - cd06624
PKc_MKK7 - cd06618
STKc_TEY_MAPK_plant - cd07858
STKc_myosinIIIA - cd06638
PTKc_EGFR_like - cd05057
PTKc_EGFR - cd05108
STKc_CDK10 - cd07845
PTKc_FAK - cd05056
STKc_nPKC_theta_delt - cd05592
PTKc_ALK_LTK - cd05036
STKc_Sty1_Hog1 - cd07856
STKc_PFTAIRE2 - cd07870
STKc_BUR1 - cd07866
PTKc_Trk - cd05049
STKc_ERK5 - cd07855
STKc_MAPK15 - cd07852
STKc_PCTAIRE2 - cd07872
STKc_PCTAIRE3 - cd07871
STKc_PCTAIRE1 - cd07873
STKc_PFTAIRE1 - cd07869
PTKc_Frk_like - cd05068
PTKc_Src_like - cd05034
PTKc_Tyk2_rpt2 - cd05080
STKc_ERK1_2_like - cd07849
STKc_PCTAIRE_like - cd07844
STKc_CDK12 - cd07864
STKc_STK25-YSK1 - cd06642
STKc_MST1_2 - cd06612
PTKc_Musk - cd05050
STKc_MAP4K3_like - cd06613
STKc_MEKK3_like_1 - cd06653
STKc_MEKK2 - cd06652
STKc_STK10_LOK - cd06644
STKc_MEKK3 - cd06651
PTKc_Srm_Brk - cd05148
PKc_MKK5 - cd06619
STKc_NAK1_like - cd06917
STKc_MAPK4_6 - cd07854
SPS1 - COG0515
PKc_MKK3_6 - cd06617
Pkinase_Tyr - pfam07714
STKc_Nek7 - cd08229
PKc_MAPKK_plant_like - cd06623
STKc_phototropin_lik - cd05574
STKc_ROCK_NDR_like - cd05573
PKc_MEK - cd06615
STKc_PKA - cd05580
STKc_MAST - cd05609
PKc_MAPKK - cd06605
STKc_MST3_like - cd06609
STKc_PRKX_like - cd05612
STKc_Nek9 - cd08221
STKc_Nek2 - cd08217
STKc_Nek8 - cd08220
STKc_Nek - cd08215
STKc_CDK2_3 - cd07860
STKc_TDY_MAPK_plant - cd07859
STKc_CDK1_euk - cd07861
STKc_CDK6 - cd07862
STKc_CDK4 - cd07863
STKc_Nek5 - cd08225
STKc_FA2-like - cd08529
STKc_CNK2-like - cd08530
STKc_MPK1 - cd07857
STKc_Nek10 - cd08528
STKc_Nek3 - cd08219
STKc_Nek4 - cd08223
STKc_Nek6_Nek7 - cd08224
STKc_Nek6 - cd08228
STKc_Nek11 - cd08222
STKc_myosinIII_like - cd06608
STKc_GRK4_like - cd05605
STKc_MSK1_N - cd05613
STKc_GRK6 - cd05630
STKc_GRK4 - cd05631
STKc_Yank1 - cd05578
STKc_MSK_N - cd05583
STKc_NLK - cd07853
PTKc_Ror - cd05048
PKc_STE - cd05122
STKc_GRK5 - cd05632
STKc_MSK2_N - cd05614
STKc_CdkB_plant - cd07837
STKc_MAPKKK - cd06606
STKc_CDK7 - cd07841
STKc_CDKL1_4 - cd07847
STKc_Pho85 - cd07836
STKc_CDK5 - cd07839
STKc_YSK4 - cd06631
STKc_Cdc7_like - cd06627
STKc_MAPK - cd07834
STKc_CDKL2_3 - cd07846
STKc_CDK9_like - cd07840
STKc_CDK4_6_like - cd07838
STKc_CDK8 - cd07868
TyrKc - smart00219
Pkinase - pfam00069
STKc_CDK1_like - cd07835
STYKc - smart00221
STKc_SLK_like - cd06611
STKc_PDK1 - cd05581
STKc_MAK_like - cd07830
STKc_CMGC - cd05118
PTKc_Btk_Bmx - cd05113
PTKc_Jak2_Jak3_rpt2 - cd05081
STKc_PKN - cd05589
STKc_CRIK - cd05601
STKc_SLK - cd06643
PKc_MKK4 - cd06616
STKc_CDK_like - cd07829
STKc_MAP4K3 - cd06645
STKc_MEKK3_like - cd06625
STKc_p70S6K - cd05584
STKc_MAPKKK_Bck1_lik - cd06629
PKc_MAPKK_PBS2_like - cd06622
STKc_MEKK1 - cd06630
STKc_CCRK - cd07832
STKc_OSR1_SPAK - cd06610
STKc_CDC2L1 - cd07843
STKc_MOK - cd07831
PTKc_Fes_like - cd05041
STKc_nPKC_theta - cd05619
PTKc_Fes - cd05084
PTKc_Syk_like - cd05060
PTKc - cd00192
PTKc_Fer - cd05085
STKc_PKC - cd05570
STKc_SGK2 - cd05603
STKc_SGK1 - cd05602
STKc_SGK - cd05575
STKc_PKB - cd05571
PTKc_Ack_like - cd05040
STKc_MEKK1_plant - cd06632
STKc_beta_ARK - cd05606
STKc_CDKL - cd07833
STKc_GRK3 - cd05633
PKc_MAPKK_Pek1_like - cd06621
STKc_GRK1 - cd05608
STKc_YPK1_like - cd05585
STKc_GRK7 - cd05607
STKc_AGC - cd05123
PKc - cd00180
STKc_MAST_like - cd05579
STKc_GRK - cd05577
STKc_cGK_PKG - cd05572
STKc_MEKK4 - cd06626
S_TKc - smart00220
STKc_CDK8_like - cd07842
KIND - smart00750
Ribonuc_2-5A - pfam06479
PUG - smart00580


Swiss-Prot Protein: Q76MJ5
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
STKc_myosinIIIBcd066390.00011493782
STKc_TAO1cd066351.2e-05497814
STKc_JNK2cd078760.001498821
STKc_TAO3cd066330.00024500825
STKc_MAP4K4_6cd066360.00015502781
STKc_JNKcd078503.1e-05503805
STKc_TNIKcd066370.0001504781
STKc_p38cd078516.8e-09504836
STKc_PAK_Icd066471.6e-05505804
STKc_PAK_IIcd066484.8e-07505795
STKc_PAK1cd066542.7e-05505806
STKc_PAK2cd066550.0001505807
STKc_PAK3cd066564.9e-06505804
STKc_TAOcd066075.3e-05506821
PKc_MAPKK_Byr1_likecd066202.1e-05506798
STKc_TAO2cd066341.6e-06506826
STKc_MST4cd066407.5e-05506802
STKc_MST3cd066411.9e-05506802
PTKc_Jak_rpt2cd050387e-06507779
STKc_PAKcd066141.8e-11507794
STKc_MAPKKK_Byr2_likcd066283.4e-10508781
STKc_PAK4cd066570.00099508800
STKc_PAK5cd066580.00065508798
STKc_PAK6cd066596.9e-08508804
STKc_CDK9cd078653.8e-08508781
STKc_Nek1cd082186.6e-05508781
STKc_MAP4K5cd066463.4e-06510780
PK_STRADcd082168.3e-05510800
PKc_MKK7cd066186.4e-07511804
STKc_ASKcd066245.1e-06511781
PTKc_EGFR_likecd050570.0006512795
PTKc_EGFRcd051080.00019512830
STKc_myosinIIIAcd066381.7e-05512781
STKc_TEY_MAPK_plantcd078589.6e-06512859
PTKc_ALK_LTKcd050362.4e-06513781
PTKc_FAKcd050560.00024513802
STKc_nPKC_theta_deltcd055920.00046513843
STKc_CDK10cd078456.6e-08513791
PTKc_Trkcd050492.7e-05514800
STKc_MAPK15cd078523.3e-06514827
STKc_ERK5cd078552.9e-07514814
STKc_Sty1_Hog1cd078562.4e-06514814
STKc_BUR1cd078662e-09514781
STKc_PFTAIRE2cd078702.9e-06514781
PTKc_Src_likecd050343.7e-05515780
PTKc_Frk_likecd050689e-05515780
PTKc_Tyk2_rpt2cd050805.3e-05515803
STKc_PCTAIRE_likecd078444.3e-06515819
STKc_ERK1_2_likecd078491.4e-06515813
STKc_PFTAIRE1cd078692.7e-05515793
STKc_PCTAIRE3cd078710.00014515781
STKc_PCTAIRE2cd078720.00036515839
STKc_PCTAIRE1cd078730.00043515793
PTKc_Muskcd050507e-05516778
STKc_MST1_2cd066126.2e-10516781
STKc_MAP4K3_likecd066131.2e-11516780
STKc_STK25-YSK1cd066422.6e-05516802
STKc_CDK12cd078643.5e-07516781
PTKc_Srm_Brkcd051483.2e-05517791
STKc_STK10_LOKcd066443.7e-05517802
STKc_MEKK3cd066519.4e-07517783
STKc_MEKK2cd066527.9e-05517782
STKc_MEKK3_like_1cd066532.9e-05517781
STKc_ROCK_NDR_likecd055738.2e-08518832
STKc_phototropin_likcd055741.7e-06518793
STKc_PKAcd055802.8e-06518841
STKc_MASTcd056090.00015518821
STKc_PRKX_likecd056122.7e-05518824
PKc_MAPKKcd066051.3e-08518787
STKc_MST3_likecd066091.6e-06518798
PKc_MEKcd066150.00011518798
PKc_MKK3_6cd066178.8e-06518803
PKc_MKK5cd066190.0009518806
PKc_MAPKK_plant_likecd066233.6e-10518786
STKc_NAK1_likecd069177.1e-08518789
STKc_MAPK4_6cd078542.8e-06518813
STKc_Nek7cd082291.1e-06518790
SPS1COG05154e-30518916
PTKc_Rorcd050480.00028519765
PKc_STEcd051221.4e-13519780
STKc_MSK_Ncd055837.5e-06519796
STKc_Yank1cd055784.5e-08519781
STKc_GRK4_likecd056051.5e-06519806
STKc_MSK1_Ncd056130.00018519793
STKc_MSK2_Ncd056144.8e-05519846
STKc_GRK6cd056300.00025519806
STKc_GRK4cd056310.00024519806
STKc_GRK5cd056326e-05519806
STKc_MAPKKKcd066066.5e-18519781
STKc_myosinIII_likecd066088.1e-07519781
STKc_Cdc7_likecd066278e-13519781
STKc_YSK4cd066311.8e-09519781
STKc_MAPKcd078347.7e-10519812
STKc_Pho85cd078361.7e-05519781
STKc_CdkB_plantcd078371.5e-09519782
STKc_CDK5cd078398.2e-09519781
STKc_CDK7cd078414e-10519789
STKc_CDKL1_4cd078474.5e-06519812
STKc_NLKcd078533.3e-06519878
STKc_MPK1cd078571.2e-06519846
STKc_TDY_MAPK_plantcd078592.6e-07519859
STKc_CDK2_3cd078608e-07519781
STKc_CDK1_eukcd078611.9e-05519781
STKc_CDK6cd078621.7e-05519781
STKc_CDK4cd078631.6e-07519781
STKc_Nekcd082154.2e-15519781
STKc_Nek2cd082175.8e-08519781
STKc_Nek8cd082206.5e-07519781
STKc_Nek9cd082211.9e-06519781
STKc_Nek11cd082220.00017519781
STKc_Nek4cd082230.00011519781
STKc_Nek6_Nek7cd082243.4e-07519790
STKc_Nek5cd082254.1e-05519781
STKc_Nek6cd082283.4e-05519790
STKc_Nek3cd082193.8e-08519781
STKc_Nek10cd085282.5e-06519781
STKc_FA2-likecd085299.8e-06519781
STKc_CNK2-likecd085304.6e-06519781
PTKc_Jak2_Jak3_rpt2cd050814.3e-05520792
PTKc_Btk_Bmxcd051130.001520780
STKc_CMGCcd051181.1e-12520781
STKc_PDK1cd055815.9e-12520781
STKc_CRIKcd056016e-05520819
STKc_PKNcd055890.00062520842
STKc_SLK_likecd066111.3e-06520793
PKc_MKK4cd066167.7e-06520795
STKc_SLKcd066430.00012520797
STKc_CDK_likecd078291.5e-14520781
STKc_MAK_likecd078302.3e-11520781
STKc_CDK1_likecd078353.7e-06520781
STKc_CDK4_6_likecd078381.7e-12520781
STKc_CDK9_likecd078401.1e-10520781
STKc_CDKL2_3cd078468.4e-07520781
STKc_CDK8cd078680.00082520781
STKc_MAP4K3cd066452.1e-05521780
STKc_MEKK3_likecd066251e-10522781
STKc_p70S6Kcd055840.00021523843
PTKccd001923.4e-08524780
PTKc_Ack_likecd050408.5e-07524767
PTKc_Fes_likecd050416e-06524767
PTKc_Syk_likecd050600.00065524767
PTKc_Fescd050840.00048524781
PTKc_Fercd050850.00043524778
STKc_PKCcd055708.9e-06524819
STKc_PKBcd055710.00058524844
STKc_SGKcd055750.00021524832
STKc_SGK1cd056020.00027524838
STKc_SGK2cd056037.6e-05524848
STKc_nPKC_thetacd056190.00019524830
STKc_OSR1_SPAKcd066106.5e-11524781
PKc_MAPKK_PBS2_likecd066228.7e-06524805
STKc_MAPKKK_Bck1_likcd066297.2e-11524781
STKc_MEKK1cd066301.5e-07524782
STKc_MOKcd078314.1e-11524781
STKc_CDC2L1cd078437.1e-08524781
STKc_CCRKcd078323.1e-10524782
STKc_beta_ARKcd056061.1e-05525801
STKc_GRK3cd056330.00018525802
STKc_MEKK1_plantcd066322.6e-13525781
STKc_CDKLcd078337e-09525781
PKccd001802.7e-46526779
STKc_AGCcd051232.9e-11526781
STKc_GRKcd055771.3e-07526810
STKc_MAST_likecd055792.3e-09526782
STKc_YPK1_likecd055858.6e-05526841
STKc_cGK_PKGcd055721.6e-07526784
STKc_GRK7cd056076.5e-05526805
STKc_GRK1cd056084.4e-06526805
PKc_MAPKK_Pek1_likecd066213.3e-05526795
STKc_MEKK4cd066263.3e-11528781
STKc_CDK8_likecd078421.9e-07533781
Pkinasepfam000698.5e-41520781
PQQsmart005641e-053465
Pkinase_Tyrpfam077141.9e-10518781
TyrKcsmart002191.9e-10520781
STYKcsmart002212.2e-43520781
S_TKcsmart002208.9e-42529781
KINDsmart007500.00027596788
Ribonuc_2-5Apfam064791.2e-73786912
PUGsmart005805.7e-24844899

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_040499Polymorphismp.ALA318THRN/A
Swiss-ProtVAR_040496Polymorphismp.ARG118CYSN/A
Swiss-ProtVAR_040497Polymorphismp.ARG184CYSN/A
Swiss-ProtVAR_040498Polymorphismp.ARG271GLNN/A
Swiss-ProtVAR_040503Polymorphismp.ARG537GLNN/A
Swiss-ProtVAR_040504Polymorphismp.HIS858TYRN/A
Swiss-ProtVAR_040500Polymorphismp.LEU410PHEN/A
Swiss-ProtVAR_040502Polymorphismp.LEU504PHEN/A
Swiss-ProtVAR_040501Polymorphismp.SER487THRN/A
Swiss-ProtVAR_040495Polymorphismp.VAL69ILEN/A



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