Results for the protein: NP

Results for the Protein: NP_006085

33188437

10395

DLC1

NCBI

rho GTPase-activating protein 7 isoform 2 [Homo sapiens]

Known Diseases associated with this Protein:
COLORECTAL CANCER, SOMATIC

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RefSeq Protein: NP_006085

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
RhoGAP_nadrin	cd04386	4e-12	635	853
RhoGAP_Graf	cd04374	3.6e-08	636	808
RhoGAP_srGAP	cd04383	1.3e-09	637	813
RhoGAP_ARHGAP22_24_2	cd04390	1.8e-08	637	847
RhoGAP_FAM13A1a	cd04393	1.1e-12	637	817
RhoGAP_CdGAP	cd04384	4.8e-10	637	828
RhoGAP_ARHGAP18	cd04391	1.1e-23	638	858
RhoGAP-ARHGAP11A	cd04394	1.1e-19	638	854
RhoGAP_ARHGAP21	cd04395	1.1e-06	638	797
RhoGAP_fBEM3	cd04400	1.6e-05	638	800
RhoGAP_ARHGAP20	cd04402	7.2e-09	638	808
RhoGAP_fSAC7_BAG7	cd04396	3.5e-08	638	811
RhoGAP_chimaerin	cd04372	6.7e-08	639	847
RhoGAP_p190	cd04373	9.9e-10	639	823
RhoGAP_myosin_IX	cd04377	1.8e-10	639	842
RhoGAP_GMIP_PARG1	cd04378	3.9e-10	639	833
RhoGAP_SYD1	cd04379	2.9e-09	639	850
RhoGap_RalBP1	cd04381	6.4e-10	639	811
RhoGAP_Bcr	cd04387	1.3e-06	639	842
RhoGAP_KIAA1688	cd04389	6.1e-05	639	829
RhoGAP_fLRG1	cd04397	2.9e-09	639	853
RhoGAP_fRGD1	cd04398	1.1e-11	639	812
RhoGAP_ARHGAP27_15_1	cd04403	3.9e-10	639	842
RhoGAP-p50rhoGAP	cd04404	9.6e-14	639	819
RhoGAP_myosin_IXA	cd04406	1.8e-08	639	842
RhoGAP_myosin_IXB	cd04407	7.6e-15	639	828
RhoGAP_GMIP	cd04408	3e-07	639	833
RhoGAP_PARG1	cd04409	2.8e-07	639	833
RhoGAP_ARAP	cd04385	3.8e-12	640	813
RhoGAP_ARHGAP6	cd04376	5.4e-15	646	853
RhoGAP_ARHGAP19	cd04392	2e-10	650	859
RhoGAP	cd00159	1.4e-53	655	842
RhoGAP_MgcRacGAP	cd04382	2.2e-05	660	814
START_1	cd08876	0.00039	867	1086
START_STARD8-like	cd08907	1.1e-92	878	1081
START_STARD12-like	cd08908	2.5e-181	878	1081
START_STARD13-like	cd08909	1.4e-105	878	1081
START_STARD4_5_6-lik	cd08867	0.00073	882	1073
START_STARD10-like	cd08871	7.5e-07	885	1090
START_RhoGAP	cd08869	2.7e-143	886	1081
START	cd00177	1.3e-23	893	1079
RhoGAP	pfam00620	4.5e-55	655	805
START	pfam01852	4.3e-70	886	1085
SAM_2	pfam07647	8.4e-10	11	76
RhoGAP	smart00324	6.2e-55	652	843
START	smart00234	1.8e-60	886	1087

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs532841	Polymorphism	p.VAL354MET	N/A
OMIM	604258.0001	Disease	p.THR85ALA	COLORECTAL CANCER, SOMATIC

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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