Results for the protein: Q8IV61

Results for the Protein: Q8IV61

34395670

25780

RASGRP3

NCBI, UniProt

GRP3_HUMAN RecName: Full=Ras guanyl-releasing protein 3; AltName: Full=Calcium and DAG-regulated guanine nucleotide exchange factor III; AltName: Full=Guanine nucleotide exchange factor for Rap1

			0 1 0 1 0

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

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Default View: RasGEFN - smart00229 RasGEF_N - pfam00618 REM - cd06224 RasGEF - smart00147 RasGEF - cd00155 RasGEF - pfam00617 EFh - cd00051 efhand - pfam00036 C1 - smart00109 C1 - cd00029 C1_1 - pfam00130	Swiss-Prot Protein: Q8IV61 Identical to: NP_733772, NP_001132960 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
RasGEF	cd00155	5.1e-104	148	379
EFh	cd00051	0.00042	424	479
C1	cd00029	2.9e-20	495	544
RasGEF_N	pfam00618	4.1e-06	6	102
RasGEF	pfam00617	6.2e-71	149	332
efhand	pfam00036	0.00038	424	452
C1_1	pfam00130	2.7e-17	495	547
RasGEFN	smart00229	6.1e-14	3	125
RasGEF	smart00147	2.7e-104	148	384
C1	smart00109	1.4e-17	495	544

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs13388394	Polymorphism	p.THR393ALA	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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