Results for the protein: P21127

Results for the Protein: P21127

34978359

984

CDK11B

NCBI, UniProt

CD11B_HUMAN RecName: Full=Cyclin-dependent kinase 11B; AltName: Full=Cell division cycle 2-like protein kinase 1; Short=CLK-1; AltName: Full=Cell division protein kinase 11B; AltName: Full=Galactosyltransferase-associated protein kinase p58/GTA; AltName: Full=PITSLRE serine/threonine-protein kinase CDC2L1; AltName: Full=p58 CLK-1

			0 11 0 0 11

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Swiss-Prot Protein: P21127

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK2	cd05621	0.00021	399	764
STKc_ROCK1	cd05622	0.00064	399	765
STKc_PAK6	cd06659	8.7e-07	413	752
STKc_JNK1	cd07875	8.6e-18	413	769
PTKc_FGFR4	cd05099	0.00012	415	709
STKc_p38alpha_MAPK14	cd07877	9.9e-27	415	755
STKc_PAK	cd06614	5.9e-14	417	738
STKc_p38	cd07851	3.2e-25	418	749
STKc_p38beta_MAPK11	cd07878	3.4e-30	418	772
STKc_p38delta_MAPK13	cd07879	3e-36	418	755
STKc_p38gamma_MAPK12	cd07880	5.6e-32	418	755
STKc_TAO3	cd06633	4.4e-05	419	715
STKc_PAK5	cd06658	2.8e-05	419	738
STKc_MAP4K4_6	cd06636	0.00025	419	723
STKc_JNK2	cd07876	5.7e-18	420	767
PTKc_Ror1	cd05090	0.00065	421	691
PTKc_DDR2	cd05095	0.0002	421	698
STKc_PAK4	cd06657	4.2e-05	421	748
STKc_myosinIIIB	cd06639	8.1e-06	422	705
STKc_TAO2	cd06634	5e-08	423	716
STKc_PAK_I	cd06647	4.1e-06	423	719
STKc_PAK_II	cd06648	1.8e-08	424	734
STKc_PAK2	cd06655	1.7e-05	424	722
STKc_PAK3	cd06656	8.2e-07	424	723
STKc_PAK1	cd06654	9.7e-07	424	721
STKc_STK10_LOK	cd06644	5e-06	425	722
STKc_CDK9	cd07865	2e-78	425	723
PTKc_FGFR	cd05053	3.6e-05	426	705
STKc_myosinIIIA	cd06638	1.6e-05	426	704
STKc_TAO	cd06607	7.5e-07	427	706
STKc_TAO1	cd06635	1.7e-06	427	729
PTKc_Ror2	cd05091	0.00056	428	706
STKc_MAP4K3	cd06645	3.3e-08	428	722
STKc_MAP4K5	cd06646	1.8e-07	428	722
PKc_MKK7	cd06618	2.1e-08	428	694
STKc_ASK	cd06624	9.4e-13	429	697
STKc_TNIK	cd06637	4.8e-05	429	689
STKc_BUR1	cd07866	4.2e-98	429	723
STKc_CDK10	cd07845	4.1e-182	430	739
STKc_JNK3	cd07874	2.2e-23	430	780
STKc_CDK12	cd07864	6.3e-92	431	723
STKc_JNK	cd07850	1.1e-31	431	746
STKc_PCTAIRE2	cd07872	2.9e-72	431	738
STKc_PCTAIRE1	cd07873	1.1e-72	431	737
PTKc_Abl	cd05052	4.8e-07	432	692
PTKc_Csk	cd05082	4.2e-05	432	691
STKc_CDC2L1	cd07843	2.1e-247	432	723
STKc_TEY_MAPK_plant	cd07858	2.9e-58	432	783
PTKc_Src_like	cd05034	7.9e-08	433	691
PTKc_Srm_Brk	cd05148	6.4e-07	433	691
STKc_MST4	cd06640	4.6e-06	433	707
STKc_MST3	cd06641	1.4e-05	433	710
STKc_STK25-YSK1	cd06642	9.3e-07	433	707
STKc_SLK	cd06643	3.4e-07	433	718
PTKc_InsR_like	cd05032	2.5e-05	434	694
PTKc_EphR	cd05033	4.8e-07	434	675
PTKc_ALK_LTK	cd05036	8.7e-06	434	697
PTKc_Csk_like	cd05039	4.9e-06	434	657
PTK_Ryk	cd05043	0.00022	434	654
PTK_CCK4	cd05046	1.9e-05	434	676
PTKc_Trk	cd05049	1.4e-06	434	686
PTKc_FAK	cd05056	1.2e-05	434	696
PTKc_InsR	cd05061	0.00046	434	707
PTKc_EphR_A2	cd05063	0.00034	434	704
PTKc_EphR_B	cd05065	1.8e-05	434	701
PTKc_EphR_A	cd05066	0.00034	434	704
PTKc_Frk_like	cd05068	1.9e-07	434	691
PTKc_Fyn_Yrk	cd05070	0.00013	434	695
PTKc_Lyn	cd05072	9.5e-06	434	703
PTKc_Chk	cd05083	4.6e-05	434	691
PTKc_Ror	cd05048	7.9e-07	434	691
PTKc_TrkA	cd05092	4.3e-05	434	705
PTKc_Itk	cd05112	6.5e-07	434	696
PTKc_Tec_Rlk	cd05114	2.3e-06	434	696
PTKc_Btk_Bmx	cd05113	5.1e-08	434	696
STKc_MAP4K3_like	cd06613	1.4e-13	434	722
PKc_MKK4	cd06616	1.5e-05	434	692
STKc_PCTAIRE_like	cd07844	1.1e-90	434	723
STKc_ERK5	cd07855	2.3e-27	434	754
STKc_PFTAIRE1	cd07869	4.4e-66	434	731
STKc_PFTAIRE2	cd07870	2.6e-72	434	723
STKc_PCTAIRE3	cd07871	2.9e-75	434	723
PTKc_Jak2_Jak3_rpt2	cd05081	9.4e-06	435	701
STKc_myosinIII_like	cd06608	1.9e-09	435	682
STKc_MAPK15	cd07852	1e-26	435	749
STKc_CDC2L6	cd07867	2.8e-44	435	723
STKc_CDK8	cd07868	1.2e-45	435	723
STKc_Nek6_Nek7	cd08224	1.8e-09	435	702
STKc_Nek6	cd08228	2.7e-07	435	699
STKc_Nek7	cd08229	4.9e-09	435	690
PTKc_Jak_rpt2	cd05038	4.2e-07	436	726
PTKc_Musk	cd05050	4.5e-05	436	686
PTKc_Lck_Blk	cd05067	7.6e-05	436	707
PTKc_Yes	cd05069	5.3e-05	436	695
PTKc_Src	cd05071	0.00022	436	705
PTKc_Hck	cd05073	2.9e-05	436	703
STKc_ROCK_NDR_like	cd05573	7.3e-09	436	763
STKc_PKA	cd05580	1.1e-06	436	738
STKc_PDK1	cd05581	8.5e-13	436	723
STKc_DMPK_like	cd05597	1.9e-05	436	778
STKc_NDR_like	cd05599	0.00073	436	768
STKc_CRIK	cd05601	3.1e-06	436	736
STKc_Sid2p_Dbf2p	cd05600	1.3e-08	436	795
STKc_MAST	cd05609	7.1e-07	436	748
STKc_PRKX_like	cd05612	3.6e-07	436	739
STKc_MRCK_alpha	cd05623	2.8e-05	436	779
STKc_MRCK_beta	cd05624	2.5e-05	436	778
STKc_NDR1	cd05628	0.00032	436	776
PKc_MAPKK	cd06605	4.8e-10	436	687
STKc_MST3_like	cd06609	4.9e-11	436	673
STKc_OSR1_SPAK	cd06610	6.7e-11	436	723
STKc_MST1_2	cd06612	8.1e-11	436	723
PKc_MEK	cd06615	6e-08	436	734
PKc_MKK3_6	cd06617	1.9e-07	436	694
PKc_MKK5	cd06619	0.00097	436	746
PKc_MAPKK_Byr1_like	cd06620	1.1e-05	436	736
PKc_MAPKK_PBS2_like	cd06622	1.3e-05	436	711
PKc_MAPKK_plant_like	cd06623	7.3e-13	436	676
STKc_MEKK3_like	cd06625	6.5e-12	436	697
PKc_MEK2	cd06649	7.7e-05	436	754
STKc_MEKK2	cd06652	4.1e-06	436	690
STKc_MEKK3_like_1	cd06653	1.1e-06	436	689
PKc_MAPKK_Pek1_like	cd06621	4.3e-07	436	693
STKc_NAK1_like	cd06917	2.6e-09	436	748
STKc_CDKL	cd07833	2.9e-48	436	723
STKc_CdkB_plant	cd07837	2.6e-96	436	724
STKc_CDKL2_3	cd07846	6.9e-43	436	723
STKc_CDKL1_4	cd07847	2.9e-62	436	723
STKc_CDKL5	cd07848	2.9e-57	436	723
STKc_ERK1_2_like	cd07849	1.4e-45	436	780
STKc_CDK6	cd07862	4.1e-68	436	723
SPS1	COG0515	4.9e-48	436	792
PTKc_Jak1_rpt2	cd05079	3.1e-05	437	727
PKc_STE	cd05122	1.5e-15	437	722
STKc_Yank1	cd05578	1.7e-11	437	723
STKc_MSK_N	cd05583	1.3e-06	437	732
STKc_cPKC	cd05587	1.1e-06	437	777
STKc_GRK4_like	cd05605	3.6e-07	437	732
STKc_MSK1_N	cd05613	7.7e-06	437	732
STKc_MSK2_N	cd05614	5.9e-07	437	756
STKc_cPKC_alpha	cd05615	4.1e-06	437	777
STKc_cPKC_beta	cd05616	3.2e-05	437	779
STKc_GRK6	cd05630	0.00052	437	727
STKc_GRK4	cd05631	0.00044	437	732
STKc_GRK5	cd05632	4.3e-05	437	727
STKc_MAPKKK	cd06606	1.1e-23	437	723
STKc_MEKK4	cd06626	2.3e-12	437	723
STKc_Cdc7_like	cd06627	5.2e-15	437	723
STKc_MAPKKK_Byr2_lik	cd06628	3.3e-08	437	697
STKc_MEKK1	cd06630	9.5e-08	437	683
STKc_YSK4	cd06631	1e-08	437	723
STKc_MEKK3	cd06651	5e-08	437	699
STKc_CCRK	cd07832	1.5e-108	437	724
STKc_MAPK	cd07834	1.4e-53	437	757
STKc_Pho85	cd07836	3.2e-93	437	723
STKc_CDK5	cd07839	3.7e-100	437	723
STKc_CDK7	cd07841	1e-115	437	736
STKc_CDK8_like	cd07842	1.8e-80	437	723
STKc_NLK	cd07853	9.7e-26	437	791
STKc_MAPK4_6	cd07854	9.8e-28	437	750
STKc_MPK1	cd07857	9.5e-26	437	747
STKc_TDY_MAPK_plant	cd07859	3e-40	437	783
STKc_CDK2_3	cd07860	1.4e-107	437	723
STKc_CDK1_euk	cd07861	7e-104	437	723
STKc_CDK4	cd07863	1.3e-75	437	723
STKc_Nek	cd08215	1.1e-20	437	671
STKc_Nek2	cd08217	1.5e-14	437	674
STKc_Nek1	cd08218	4.2e-19	437	689
STKc_Nek3	cd08219	6e-17	437	697
STKc_Nek8	cd08220	1.7e-09	437	697
STKc_Nek11	cd08222	1.8e-09	437	723
STKc_Nek4	cd08223	1.2e-12	437	689
STKc_Nek5	cd08225	3.1e-22	437	689
STKc_FA2-like	cd08529	5.5e-12	437	671
STKc_CNK2-like	cd08530	2.2e-11	437	697
STKc_Nek10	cd08528	1.4e-08	437	694
PTKc_Axl_like	cd05035	0.00033	438	692
PTKc_Tyk2_rpt2	cd05080	2e-06	438	702
STKc_CMGC	cd05118	5.3e-121	438	723
STKc_PKN	cd05589	3.5e-08	438	778
STKc_CDK_like	cd07829	3.9e-174	438	723
STKc_MOK	cd07831	2.1e-42	438	723
STKc_CDK4_6_like	cd07838	9.7e-83	438	723
STKc_CDK1_like	cd07835	6.6e-106	438	723
STKc_CDK9_like	cd07840	1.9e-129	438	723
STKc_MAK_like	cd07830	5.3e-58	438	723
STKc_Sty1_Hog1	cd07856	1.1e-23	438	738
STKc_phototropin_lik	cd05574	0.00034	439	746
PTKc_Tec_like	cd05059	5.2e-07	441	696
STKc_RSK_N	cd05582	4.3e-06	441	754
STKc_p70S6K	cd05584	9.3e-06	441	780
STKc_Rim15_like	cd05611	3.4e-07	441	725
STKc_SLK_like	cd06611	1.9e-07	441	694
PTKc	cd00192	2.7e-10	442	696
PTKc_Ack_like	cd05040	2.5e-08	442	694
PTKc_Fes_like	cd05041	1.5e-08	442	686
PTKc_Aatyk	cd05042	0.00059	442	706
PTKc_c-ros	cd05044	6.5e-07	442	686
PTKc_Met_Ron	cd05058	2.2e-05	442	701
PTKc_Syk_like	cd05060	1.3e-06	442	681
PTKc_Fes	cd05084	8.3e-06	442	697
PTKc_Fer	cd05085	1.3e-06	442	697
PTKc_Aatyk2	cd05086	0.00054	442	706
PTKc_Syk	cd05116	9.8e-06	442	689
STKc_PKB	cd05571	7.1e-07	442	765
STKc_SGK	cd05575	1.9e-06	442	765
STKc_aPKC	cd05588	1.6e-05	442	779
STKc_nPKC_eta	cd05590	1.8e-05	442	752
STKc_nPKC_epsilon	cd05591	7.7e-07	442	779
STKc_nPKC_theta_delt	cd05592	9.7e-07	442	756
STKc_PKB_alpha	cd05594	1.4e-05	442	766
STKc_PKB_beta	cd05595	0.00064	442	765
STKc_PKB_gamma	cd05593	5.9e-05	442	768
STKc_SGK1	cd05602	2e-05	442	756
STKc_SGK2	cd05603	3.2e-06	442	755
STKc_aPKC_zeta	cd05617	2.3e-05	442	742
STKc_aPKC_iota	cd05618	0.00014	442	742
STKc_nPKC_theta	cd05619	1.6e-06	442	756
PTKc_Zap-70	cd05115	8.3e-06	443	693
PKc	cd00180	1.5e-62	444	721
STKc_AGC	cd05123	1.4e-12	444	723
STKc_GRK	cd05577	1.1e-06	444	737
STKc_cGK_PKG	cd05572	8.5e-09	444	725
STKc_MAST_like	cd05579	1.3e-11	444	732
STKc_YPK1_like	cd05585	3.5e-06	444	752
STKc_Sck1_like	cd05586	1.1e-05	444	791
STKc_beta_ARK	cd05606	7.7e-06	444	714
STKc_GRK7	cd05607	8.7e-06	444	737
STKc_GRK1	cd05608	1.7e-06	444	706
STKc_GRK3	cd05633	5e-05	444	715
STKc_MAPKKK_Bck1_lik	cd06629	7.5e-11	444	723
STKc_Nek9	cd08221	5.8e-10	446	723
STKc_PKC	cd05570	1e-07	447	754
STKc_MEKK1_plant	cd06632	1e-11	447	723
Pkinase	pfam00069	1.4e-86	438	723
TyrKc	smart00219	5.3e-12	438	688
STYKc	smart00221	3.8e-89	438	723
Pkinase_Tyr	pfam07714	3.1e-13	441	674
S_TKc	smart00220	6.8e-99	448	723

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041964	Polymorphism	p.ALA670VAL	N/A
Swiss-Prot	VAR_062199	Polymorphism	p.ARG109CYS	N/A
Swiss-Prot	VAR_041958	Polymorphism	p.ARG57CYS	N/A
Swiss-Prot	VAR_041959	Polymorphism	p.ARG201TRP	N/A
Swiss-Prot	VAR_057775	Polymorphism	p.ARG93TRP	N/A
Swiss-Prot	VAR_045578	Polymorphism	p.GLY506SER	N/A
Swiss-Prot	VAR_041961	Polymorphism	p.ILE463VAL	N/A
Swiss-Prot	VAR_041962	Polymorphism	p.LEU601GLN	N/A
Swiss-Prot	VAR_041963	Polymorphism	p.LYS641ASN	N/A
Swiss-Prot	VAR_041960	Polymorphism	p.SER414LEU	N/A
Swiss-Prot	VAR_045577	Polymorphism	p.VAL452ALA	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258