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Results for the Protein:
Q92824
357529585
5125
PCSK5
NCBI
,
UniProt
PCSK5_HUMAN RecName: Full=Proprotein convertase subtilisin/kexin type 5; AltName: Full=Proprotein convertase 5; Short=PC5; AltName: Full=Proprotein convertase 6; Short=PC6; Short=hPC6; AltName: Full=Subtilisin/kexin-like protease PC5; Flags: Precursor
0
12
0
12
0
Tips:
The Domains on the Default View are decided by the Domain's E-Value.
Clicking a check box will display or hide the correlated domain.
To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.
Default View:
AprE - COG1404
Peptidases_S8_Protei - cd04059
Peptidases_S8_Thermi - cd07484
Peptidase_S8 - pfam00082
Peptidases_S8_11 - cd04843
Peptidases_S8_5 - cd07489
Peptidases_S8_Fervid - cd07485
Peptidases_S8_PCSK9_ - cd04077
Peptidases_S8_Kp43_p - cd04842
Peptidases_S8_Autotr - cd04848
Peptidases_S8_1 - cd07487
Peptidases_S8_Bacill - cd07481
Peptidases_S8_Subtil - cd07473
Peptidases_S8_subtil - cd07474
Peptidases_S8_13 - cd07496
Peptidases_S8_Lantib - cd07482
Peptidases_S8_Subtil - cd07477
Peptidases_S8_S53 - cd00306
Peptidases_S8_15 - cd07498
Peptidases_S8_Subtil - cd04847
Peptidases_S8_6 - cd07490
COG4935 - COG4935
P_proprotein - pfam01483
FU - smart00261
FU - cd00064
Swiss-Prot Protein:
Q92824
Identical to:
NP_001177411
Default View:
Domains
found on the Protein
Domain ↕
CD Accession ↕
E-Value ↕
Start ↕
End ↕
Peptidases_S8_Protei
cd04059
7.9e-178
126
420
Peptidases_S8_Thermi
cd07484
2.8e-07
140
425
Peptidases_S8_11
cd04843
0.00011
150
421
Peptidases_S8_Fervid
cd07485
1.6e-09
154
418
Peptidases_S8_5
cd07489
0.00085
154
448
Peptidases_S8_PCSK9_
cd04077
0.00016
156
421
Peptidases_S8_Kp43_p
cd04842
3e-06
157
420
Peptidases_S8_Autotr
cd04848
9.2e-13
161
420
Peptidases_S8_Subtil
cd07473
4.9e-12
162
420
Peptidases_S8_subtil
cd07474
2.4e-06
162
452
Peptidases_S8_Bacill
cd07481
6.7e-06
162
420
Peptidases_S8_1
cd07487
6.6e-07
162
420
Peptidases_S8_Subtil
cd07477
2.5e-08
164
418
Peptidases_S8_Lantib
cd07482
5.8e-05
164
418
Peptidases_S8_13
cd07496
5.8e-09
164
418
Peptidases_S8_S53
cd00306
1.4e-32
165
418
Peptidases_S8_Subtil
cd04847
0.00074
165
415
Peptidases_S8_15
cd07498
1.7e-14
165
418
Peptidases_S8_6
cd07490
0.00097
167
420
Peptidases_S8_S53
cd00306
5.2e-05
419
842
FU
cd00064
8.4e-15
635
687
FU
cd00064
7.9e-12
688
738
FU
cd00064
2.7e-07
739
783
FU
cd00064
6e-13
784
836
FU
cd00064
1.3e-11
837
886
FU
cd00064
2.1e-09
887
933
FU
cd00064
2.9e-12
934
986
FU
cd00064
1.3e-07
1037
1083
FU
cd00064
1.8e-08
1084
1129
FU
cd00064
1.5e-06
1130
1181
FU
cd00064
4.8e-12
1182
1229
FU
cd00064
3.4e-05
1230
1278
FU
cd00064
3.3e-07
1279
1324
FU
cd00064
0.00021
1325
1369
FU
cd00064
1.6e-12
1370
1419
FU
cd00064
4.3e-08
1420
1469
FU
cd00064
7.2e-15
1470
1518
FU
cd00064
1.8e-12
1519
1567
FU
cd00064
2.9e-12
1568
1618
FU
cd00064
2.1e-07
1619
1669
FU
cd00064
4.3e-05
1670
1718
Peptidase_S8
pfam00082
7e-130
145
445
COG4935
COG4935
3.5e-07
463
637
P_proprotein
pfam01483
9.7e-46
505
595
FU
smart00261
3.3e-13
630
680
FU
smart00261
5.1e-12
683
730
FU
smart00261
3e-09
734
777
FU
smart00261
4.6e-14
779
824
FU
smart00261
3.3e-12
832
879
FU
smart00261
8.6e-10
882
927
FU
smart00261
1.2e-06
929
979
FU
smart00261
2.1e-07
1032
1077
FU
smart00261
1.4e-07
1079
1121
FU
smart00261
3.9e-08
1125
1168
FU
smart00261
2.1e-12
1177
1221
FU
smart00261
3.5e-09
1225
1272
FU
smart00261
5.4e-09
1274
1318
FU
smart00261
4.2e-07
1320
1363
FU
smart00261
9.8e-11
1365
1411
FU
smart00261
4.7e-09
1415
1461
FU
smart00261
4.5e-09
1465
1510
FU
smart00261
2.7e-12
1514
1559
FU
smart00261
2.1e-13
1563
1610
FU
smart00261
4.5e-11
1614
1659
FU
smart00261
8.1e-07
1665
1712
Table of Mutations found on the Protein
Source ↕
Mut_ID ↕
Class ↕
HGVS ↕
Disease ↕
dbSNP
rs2495207
Polymorphism
p.ARG1366HIS
N/A
dbSNP
rs7036921
Polymorphism
p.ASP1699GLU
N/A
dbSNP
rs2842480
Polymorphism
p.GLU1079ALA
N/A
dbSNP
rs2803429
Polymorphism
p.GLU1414GLN
N/A
dbSNP
rs17062264
Polymorphism
p.GLY970ARG
N/A
dbSNP
rs1110222
Polymorphism
p.GLY1275ASP
N/A
dbSNP
rs2643325
Polymorphism
p.GLY1090SER
N/A
dbSNP
rs78703446
Polymorphism
p.LYS1320ARG
N/A
dbSNP
rs1110223
Polymorphism
p.LYS1320GLU
N/A
dbSNP
rs114508164
Polymorphism
p.PRO1201SER
N/A
dbSNP
rs114234833
Polymorphism
p.SER1458PHE
N/A
dbSNP
rs3001772
Polymorphism
p.THR1343MET
N/A
Please Cite:
Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.
DMDM_info@umbc.edu
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