Results for the protein: Q9UPW8

Results for the Protein: Q9UPW8

374095515

23025

UNC13A

NCBI, UniProt

UN13A_HUMAN RecName: Full=Protein unc-13 homolog A; AltName: Full=Munc13-1

			0 2 0 1 1

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Swiss-Prot Protein: Q9UPW8

Identical to: NP_001073890

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
C2	cd00030	1.4e-11	4	99
C1	cd00029	4.3e-22	554	603
C2A_Munc13-like	cd08676	2.5e-09	644	785
C2_Perforin	cd04032	5.5e-07	653	787
C2A_Synaptotagmin-7	cd08386	0.00013	659	787
C2_PKC_alpha_gamma	cd04026	2.7e-07	662	795
C2B_Synaptotagmin	cd00276	8.7e-06	665	785
C2A_Rabphilin_Doc2	cd04035	1.6e-07	667	787
C2A_SLP	cd08521	0.00041	670	785
C2C_KIAA1228	cd04030	6.1e-07	672	786
C2A_RIM1alpha	cd04031	4.5e-06	672	786
C2A_Synaptotagmin-8	cd08387	0.00055	672	787
C2B_Ferlin	cd04011	7.6e-06	673	778
C2_PKC_epsilon	cd04014	0.00046	673	810
C2_PLC_like	cd00275	2.7e-06	675	784
C2A_Synaptotagmin-1-	cd08385	5.6e-06	675	787
C2B_Synaptotagmin-7	cd08405	3.1e-05	675	799
C2B_Munc13	cd04027	3.8e-100	676	802
C2C_Tricalbin-like	cd04045	1.4e-05	676	808
C2A_Copine	cd04048	1.4e-06	676	795
C2C_MCTP_PRT	cd08377	1.6e-09	676	805
C2_fungal_Inn1p-like	cd08681	2.4e-05	676	804
C2B_RasA3	cd04010	3.6e-06	677	803
C2A_MCTP_PRT_plant	cd04022	1.7e-07	677	804
C2B_RasA1_RasA4	cd04025	1.5e-07	677	803
C2_ArfGAP	cd04038	1.2e-07	677	808
C2_cPLA2	cd04036	3.9e-05	677	787
C2E_Ferlin	cd04037	1.6e-05	677	800
C2A_Rasal1_RasA4	cd04054	3.3e-07	677	804
C2A_MCTP_PRT	cd04042	3.3e-07	677	806
C2_Smurf-like	cd08382	1.9e-07	677	803
C2A_RasGAP	cd08383	3.5e-06	677	804
C2B_Rabphilin_Doc2	cd08384	0.00077	677	785
C2D_MCTP_PRT_plant	cd08379	0.00094	677	803
C2	cd00030	3e-32	678	785
C2D_Tricalbin-like	cd04040	3.2e-08	678	801
C2A_fungal	cd04041	4.7e-07	678	788
C2A_Tricalbin-like	cd04044	0.00093	678	803
C2_Calpain	cd04046	4e-07	678	813
C2B_MCTP_PRT	cd08376	9.3e-07	678	800
C2B_RasGAP	cd08675	3.3e-07	678	798
C2_Rab11-FIP_classI	cd08682	5e-07	678	803
C2_KIAA0528-like	cd08688	2.4e-05	678	803
C2_Munc13_fungal	cd04043	1.8e-08	679	812
C2B_Synaptotagmin-li	cd04050	2.7e-06	679	790
C2A_Synaptotagmin-li	cd04024	2.3e-11	680	804
C2_NEDD4_NEDD4L	cd04033	2.7e-06	680	805
C2B_MCTP_PRT_plant	cd08378	1.4e-05	680	804
C2A_C2C_Synaptotagmi	cd08391	1.8e-10	680	804
C2A_Ferlin	cd08373	7.6e-05	681	816
C2_NEDL1-like	cd08691	2.9e-05	681	803
C2_putative_Elicitor	cd04049	0.00099	683	806
C2D_Ferlin	cd04017	0.00057	685	810
C2_PLC_like	cd00275	2.5e-05	1544	1690
C2C_Munc13	cd08395	9.8e-101	1546	1665
C2	cd00030	6.8e-15	1547	1655
C2	pfam00168	5.2e-08	4	79
C1_1	pfam00130	2.3e-16	554	606
C2	pfam00168	1e-27	678	769
C2	pfam00168	2.9e-14	1547	1637
C2	smart00239	1.4e-11	3	94
C1	smart00109	1.2e-18	554	603
C2	smart00239	1.8e-28	677	784
DUF1041	pfam06292	6.4e-65	993	1102
Membr_traf_MHD	pfam10540	5.4e-96	1345	1512
C2	smart00239	3.4e-16	1546	1652

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs75595663	Polymorphism	p.ALA1133SER	N/A
Swiss-Prot	VAR_061872	Polymorphism	p.ALA359THR	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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