Results for the protein: NP

Results for the Protein: NP_001243750

378744214

6016

RIT1

NCBI

GTP-binding protein Rit1 isoform 1 [Homo sapiens]

Known Diseases associated with this Protein:
NOONAN SYNDROME 8

4

0

4

0

0

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RefSeq Protein: NP_001243750

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Rab30	cd04114	2.3e-12	33	200
Rab9	cd04116	5.6e-20	34	199
Rnd3_RhoE_Rho8	cd04172	6.7e-05	34	202
Rab2	cd01866	2.9e-31	35	202
Rab8_Rab10_Rab13_lik	cd01867	1.8e-35	36	202
RhoG	cd01875	1.4e-11	36	209
RhoBTB	cd01873	0.00022	37	199
Rab35	cd04110	7.7e-20	37	234
Rab33B_Rab33A	cd04115	1.6e-12	37	214
Rit_Rin_Ric	cd04141	2.8e-122	37	208
M_R_Ras_like	cd04145	6.9e-76	37	200
Rab5_related	cd01860	5.3e-15	38	200
Rab3	cd01865	4.4e-21	38	202
RhoA_like	cd01870	1.5e-18	38	200
Rac1_like	cd01871	1.6e-17	38	199
Cdc42	cd01874	4.2e-14	38	199
Rho2	cd04129	2e-10	38	235
Rnd	cd04131	9.7e-06	38	201
Rop_like	cd04133	1.3e-06	38	225
Rap_like	cd04136	1.1e-79	38	200
RheB	cd04137	1.2e-44	38	221
H_N_K_Ras_like	cd04138	7.8e-75	38	200
ARHI_like	cd04140	6.1e-38	38	200
Rap1	cd04175	4.4e-66	38	201
Rap2	cd04176	5.5e-65	38	200
RSR1	cd04177	4.9e-46	38	236
Rab	cd00154	1.8e-43	39	197
Rho	cd00157	1.4e-22	39	198
Ran	cd00877	3.7e-11	39	207
Rab6	cd01861	2.6e-16	39	199
Rab7	cd01862	2e-13	39	205
Rab18	cd01863	1.5e-23	39	199
Rab19	cd01864	1.1e-10	39	199
Rab11_like	cd01868	6.6e-17	39	200
Rab1_Ypt1	cd01869	6.6e-32	39	202
RabL4	cd04101	4.4e-07	39	200
Centaurin_gamma	cd04103	0.00011	39	199
Rab23_like	cd04106	1.3e-17	39	199
Rab32_Rab38	cd04107	1.4e-08	39	235
Rab36_Rab34	cd04108	9.7e-05	39	236
Rab28	cd04109	3.8e-07	39	236
Rab39	cd04111	4.3e-09	39	236
Rab26	cd04112	1.6e-08	39	227
Rab4	cd04113	1.1e-13	39	199
Rab15	cd04117	4.4e-20	39	199
Rab24	cd04118	1.5e-08	39	236
RJL	cd04119	7.2e-10	39	201
Rab12	cd04120	5.7e-06	39	234
Rab14	cd04122	1.6e-22	39	202
Rab21	cd04123	4.7e-28	39	200
RabL2	cd04124	1.9e-06	39	202
	cd04125	3.4e-09	39	230
Rab20	cd04126	6.2e-07	39	224
Wrch_1	cd04130	2.1e-14	39	199
Rho4_like	cd04132	2.8e-11	39	236
Tc10	cd04135	3.6e-12	39	196
RalA_RalB	cd04139	4.6e-62	39	202
RRP22	cd04142	4.9e-08	39	210
Rhes_like	cd04143	2.9e-12	39	236
RGK	cd04148	7.3e-14	39	236
Ras	cd00876	2.8e-95	40	199
Arf_Arl	cd00878	8.8e-05	40	201
Miro1	cd01893	2e-06	40	194
Rab27A	cd04127	4.8e-11	40	203
Rho3	cd04134	1.5e-06	40	210
Ras2	cd04144	5.9e-54	40	236
RERG_RasL11_like	cd04146	2.2e-52	40	201
Ras_dva	cd04147	1.3e-14	40	236
Arl10_like	cd04159	2e-05	40	198
Ras_like_GTPase	cd00882	3.4e-53	43	197
Ras	pfam00071	1.2e-72	40	201
small_GTPase	smart00010	1.3e-44	36	203
RAS	smart00173	6.8e-112	39	202
RAB	smart00175	6e-32	39	202
Miro	pfam08477	1e-14	40	154
RHO	smart00174	1.3e-11	41	202
RAN	smart00176	6.6e-06	44	234

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
OMIM	609591.0001	Disease	p.ALA57GLY	NOONAN SYNDROME 8
OMIM	609591.0002	Disease	p.GLU81GLY	NOONAN SYNDROME 8
OMIM	609591.0004	Disease	p.GLY95ALA	NOONAN SYNDROME 8
OMIM	609591.0003	Disease	p.PHE82LEU	NOONAN SYNDROME 8

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258