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Results for the Protein: NP_001243778
379030588

DNA polymerase delta catalytic subunit [Homo sapiens]

Known Diseases associated with this Protein:
  COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
2
0
2
0
0
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

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Default View:

PolB - COG0417
DNA_pol_B_exo1 - pfam03104
DNA_polB_delta_exo - cd05777
DNA_polB_B1_exo - cd05783
DNA_polB_zeta_exo - cd05778
DNA_polB_II_exo - cd05784
POLBc - smart00486
DNA_polB_B3_exo - cd05781
DNA_polB_Kod1_like_e - cd05780
DNA_polB_alpha_exo - cd05776
DNA_polB_epsilon_exo - cd05779
DNA_polB_like2_exo - cd05785
DEDDy_DNA_polB_exo - cd05160
DNA_pol_B - pfam00136
POLBc_zeta - cd05534
POLBc_B1 - cd05530
POLBc_alpha - cd05532
POLBc_B3 - cd05536
POLBc_delta - cd05533
POLBc_B2 - cd05531
POLBc - cd00145
POLBc_Pol_II - cd05537
POLBc_Pol_II_B - cd05538




Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
DNA_polB_delta_exocd057779.2e-172304533
DNA_polB_B1_exocd057831.7e-05306526
DNA_polB_zeta_exocd057789.9e-11307524
DNA_polB_alpha_exocd057762.7e-06308534
DNA_polB_Kod1_like_ecd057808.1e-10308526
DNA_polB_B3_exocd057814.5e-07308526
DNA_polB_II_exocd057843.1e-09308524
DNA_polB_epsilon_exocd057798e-05309484
DNA_polB_like2_exocd057851.3e-06310524
DEDDy_DNA_polB_exocd051608.6e-75312524
POLBc_zetacd055344.4e-53550975
POLBc_B1cd055302.1e-08572965
POLBc_alphacd055327.6e-34574985
POLBc_B3cd055364.1e-30578982
POLBccd001452.9e-109579971
POLBc_B2cd055312.5e-09579970
POLBc_deltacd05533579974
POLBc_Pol_IIcd055374.4e-16586971
POLBc_Pol_II_Bcd055384.9e-08587969
DNA_pol_B_exo1pfam031041.1e-118130477
DNA_pol_Bpfam001364.8e-2115501009
POLBcsmart004861.7e-154308765

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
OMIM174761.0002 Diseasep.PRO327LEUCOLORECTAL CANCER, SUSCEPTIBILITY TO, 10
OMIM174761.0001 Diseasep.SER478ASNCOLORECTAL CANCER, SUSCEPTIBILITY TO, 10



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