Results for the protein: Q6ZWH5

Results for the Protein: Q6ZWH5

380865464

152110

NEK10

NCBI, UniProt

NEK10_HUMAN RecName: Full=Serine/threonine-protein kinase Nek10; AltName: Full=Never in mitosis A-related kinase 10; Short=NimA-related protein kinase 10

			0 7 0 0 7

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Swiss-Prot Protein: Q6ZWH5

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_PDGFR_alpha	cd05105	0.00041	415	789
STKc_ROCK	cd05596	4.7e-06	471	828
STKc_ROCK1	cd05622	1.2e-05	479	831
STKc_ROCK2	cd05621	2e-06	479	839
STKc_PAK5	cd06658	3.9e-07	492	791
STKc_TAO3	cd06633	6.1e-05	493	819
STKc_TAO1	cd06635	6.6e-06	493	823
STKc_PAK1	cd06654	2.2e-10	493	809
STKc_PAK2	cd06655	2.6e-10	494	809
STKc_PAK3	cd06656	1.6e-10	494	810
STKc_myosinIIIB	cd06639	1.1e-09	496	789
STKc_PAK_I	cd06647	4.1e-15	497	806
STKc_PAK_II	cd06648	7.2e-12	497	787
STKc_PAK6	cd06659	2.7e-10	497	815
STKc_JNK1	cd07875	9.6e-06	497	864
STKc_JNK2	cd07876	1.4e-07	497	862
STKc_myosinIIIA	cd06638	2.2e-09	499	788
STKc_TAO2	cd06634	1.3e-07	500	845
STKc_TAO	cd06607	1.1e-07	500	818
STKc_MAP4K4_6	cd06636	1.2e-05	501	783
STKc_JNK3	cd07874	2.8e-06	501	904
STKc_p38alpha_MAPK14	cd07877	3.8e-05	501	851
STKc_JNK	cd07850	8.3e-08	502	876
PTKc_FGFR	cd05053	2.6e-05	503	784
STKc_p38	cd07851	3.1e-10	503	821
STKc_p38beta_MAPK11	cd07878	7.9e-06	503	840
STKc_p38delta_MAPK13	cd07879	3.6e-05	503	851
PTKc_EGFR_like	cd05057	1.3e-07	505	789
PKc_MKK7	cd06618	1.4e-11	505	789
STKc_PAK4	cd06657	3.3e-07	505	806
STKc_p38gamma_MAPK12	cd07880	1.2e-07	505	861
STKc_PAK	cd06614	6.1e-21	506	800
STKc_STK10_LOK	cd06644	2.6e-09	506	807
STKc_CDK9	cd07865	5.1e-10	507	816
STKc_MAP4K5	cd06646	1.6e-08	508	784
PTKc_Jak1_rpt2	cd05079	1.3e-05	509	787
PTKc_Tyk2_rpt2	cd05080	6.2e-06	509	788
STKc_MAP4K3	cd06645	2.9e-08	509	784
PTKc_Ror	cd05048	7.2e-05	510	766
PTKc_Trk	cd05049	1.7e-06	510	785
PTKc_Ror1	cd05090	0.00033	510	786
PTKc_DDR2	cd05095	2.4e-05	510	785
PTKc_FGFR4	cd05099	2.2e-05	510	802
STKc_SLK	cd06643	3.4e-10	510	805
PTKc_EphR	cd05033	4.6e-06	511	787
PTKc_Jak_rpt2	cd05038	1e-08	511	787
PTK_HER3	cd05111	2.7e-06	511	797
STKc_STK25-YSK1	cd06642	1.5e-10	511	812
STKc_CDK10	cd07845	3e-10	511	821
STKc_Sty1_Hog1	cd07856	5.5e-06	511	845
PTKc_Tie2	cd05088	0.00013	512	826
PKc_MEK2	cd06649	4.5e-07	512	866
PKc_MEK1	cd06650	1e-05	512	849
PTKc_EGFR	cd05108	4.6e-07	513	833
PTKc_HER4	cd05110	6.9e-05	513	809
PTKc_HER2	cd05109	1.5e-05	513	789
PTKc_Chk	cd05083	2.6e-06	513	786
STKc_ASK	cd06624	1.2e-18	513	788
STKc_PCTAIRE_like	cd07844	1.3e-17	513	816
STKc_TEY_MAPK_plant	cd07858	5.1e-08	513	855
STKc_PFTAIRE1	cd07869	4.9e-05	513	828
STKc_PFTAIRE2	cd07870	3.8e-07	513	828
STKc_PCTAIRE3	cd07871	1e-10	513	810
STKc_PCTAIRE2	cd07872	2.6e-09	513	836
STKc_PCTAIRE1	cd07873	1e-08	513	828
PTKc_ALK_LTK	cd05036	1.9e-07	514	785
STKc_CDK12	cd07864	9.7e-13	514	816
STKc_BUR1	cd07866	2.7e-07	514	774
PTKc_Csk	cd05082	1.5e-06	515	786
PTKc_TrkA	cd05092	0.00019	515	793
PTKc_TrkB	cd05093	5.9e-05	515	792
PTK_CCK4	cd05046	4.8e-05	516	785
PTKc_EphR_A2	cd05063	7.9e-06	516	787
PTKc_EphR_A10	cd05064	6e-05	516	787
PTKc_EphR_B	cd05065	1.4e-06	516	787
PTKc_Frk_like	cd05068	3.1e-12	516	786
PTKc_Yes	cd05069	1.6e-05	516	786
PTKc_Src	cd05071	6.8e-05	516	788
PTKc_Lyn	cd05072	1.1e-06	516	786
PTKc_Tie1	cd05089	8.8e-06	516	800
PTKc_EphR_A	cd05066	7.2e-05	516	787
STKc_SLK_like	cd06611	1.7e-12	516	797
STKc_TNIK	cd06637	8.1e-07	516	783
STKc_CDC2L1	cd07843	2.1e-10	516	774
STKc_ERK5	cd07855	3e-07	516	836
STKc_CDC2L6	cd07867	0.00016	516	816
STKc_CDK8	cd07868	0.00021	516	843
PK_STRAD	cd08216	2.4e-06	516	793
STKc_Nek6	cd08228	4.4e-50	516	788
STKc_Nek7	cd08229	5e-44	516	788
STKc_Nek6_Nek7	cd08224	4.4e-51	516	788
PTKc_Musk	cd05050	3.8e-06	517	785
PTKc_FAK	cd05056	7.7e-09	517	791
PTKc_InsR	cd05061	1.6e-06	517	796
PTKc_IGF-1R	cd05062	2.2e-06	517	785
PTKc_Abl	cd05052	2.7e-09	517	787
PTKc_Lck_Blk	cd05067	0.00026	517	786
PTKc_Fyn_Yrk	cd05070	0.00022	517	786
PTKc_Hck	cd05073	2.8e-06	517	786
PTKc_DDR_like	cd05097	0.00016	517	785
PTKc_Itk	cd05112	3.5e-09	517	784
PTKc_Btk_Bmx	cd05113	6.2e-13	517	784
PTKc_Tec_Rlk	cd05114	6.8e-09	517	784
STKc_ROCK_NDR_like	cd05573	9e-13	517	839
STKc_phototropin_lik	cd05574	1.1e-07	517	784
STKc_PKA	cd05580	1.2e-14	517	815
STKc_PDK1	cd05581	8e-17	517	791
STKc_DMPK_like	cd05597	4.6e-07	517	871
STKc_LATS	cd05598	6e-08	517	880
STKc_CRIK	cd05601	8.3e-07	517	871
STKc_MAST	cd05609	7.6e-09	517	845
STKc_PRKX_like	cd05612	1.5e-09	517	816
STKc_Sid2p_Dbf2p	cd05600	6.9e-05	517	840
STKc_MRCK_alpha	cd05623	8.7e-06	517	852
STKc_MRCK_beta	cd05624	1.3e-05	517	851
STKc_LATS1	cd05625	8.1e-05	517	842
STKc_LATS2	cd05626	0.00022	517	839
STKc_NDR2	cd05627	2.9e-05	517	876
STKc_NDR1	cd05628	5e-06	517	869
STKc_NDR_like_fungal	cd05629	4.8e-05	517	856
PKc_MAPKK	cd06605	8.8e-16	517	792
STKc_myosinIII_like	cd06608	4.5e-11	517	783
STKc_MST3_like	cd06609	7.2e-15	517	787
STKc_OSR1_SPAK	cd06610	6.6e-14	517	783
PKc_MKK3_6	cd06617	1.3e-11	517	802
PKc_MAPKK_Pek1_like	cd06621	5.6e-12	517	795
PKc_MAPKK_PBS2_like	cd06622	1.1e-10	517	841
PKc_MAPKK_plant_like	cd06623	2.4e-19	517	793
PKc_MEK	cd06615	1.3e-09	517	805
STKc_MEKK2	cd06652	1.2e-08	517	786
PKc_MKK5	cd06619	6.8e-07	517	809
STKc_NAK1_like	cd06917	3.2e-13	517	791
STKc_CdkB_plant	cd07837	1.2e-10	517	817
STKc_CDKL	cd07833	1.1e-12	517	791
STKc_CDKL2_3	cd07846	7.7e-10	517	816
STKc_CDKL1_4	cd07847	5e-19	517	816
STKc_CDKL5	cd07848	4.8e-08	517	826
STKc_MAPK4_6	cd07854	1.1e-06	517	837
STKc_CDK6	cd07862	5.6e-08	517	816
SPS1	COG0515	2.5e-54	517	935
PTKc_InsR_like	cd05032	1.3e-08	518	785
PKc_STE	cd05122	2e-32	518	776
PTKc_RET	cd05045	2.4e-05	518	790
STKc_Yank1	cd05578	1.3e-18	518	788
STKc_MSK_N	cd05583	1.3e-10	518	805
STKc_cPKC	cd05587	2.2e-08	518	845
STKc_GRK4_like	cd05605	1.1e-10	518	820
STKc_MSK1_N	cd05613	8.7e-09	518	805
STKc_MSK2_N	cd05614	5.5e-09	518	852
STKc_cPKC_alpha	cd05615	2.1e-09	518	847
STKc_cPKC_beta	cd05616	3.9e-07	518	845
STKc_GRK6	cd05630	1.8e-07	518	809
STKc_GRK4	cd05631	6.3e-08	518	803
STKc_GRK5	cd05632	1e-07	518	804
STKc_MAPKKK	cd06606	2.1e-34	518	779
STKc_MAP4K3_like	cd06613	1.7e-17	518	787
STKc_Cdc7_like	cd06627	2.7e-20	518	776
STKc_MAPKKK_Byr2_lik	cd06628	6.2e-27	518	787
STKc_MEKK3_like	cd06625	6.6e-15	518	786
STKc_MEKK3	cd06651	3.5e-11	518	787
STKc_MEKK3_like_1	cd06653	2.1e-09	518	786
STKc_MAPK	cd07834	4.5e-11	518	819
STKc_Pho85	cd07836	9.6e-18	518	816
STKc_CDK5	cd07839	8.3e-10	518	816
STKc_CCRK	cd07832	9.8e-12	518	783
STKc_CDK7	cd07841	5.3e-12	518	800
STKc_CDK8_like	cd07842	6.5e-10	518	816
STKc_ERK1_2_like	cd07849	4.5e-06	518	821
STKc_MAPK15	cd07852	5.7e-11	518	818
STKc_MPK1	cd07857	1.4e-08	518	857
STKc_TDY_MAPK_plant	cd07859	2.9e-08	518	865
STKc_CDK2_3	cd07860	3.6e-07	518	816
STKc_CDK4	cd07863	3e-12	518	810
STKc_CDK1_euk	cd07861	8.4e-16	518	816
STKc_NLK	cd07853	3.5e-05	518	856
STKc_Nek	cd08215	3.8e-119	518	785
STKc_Nek2	cd08217	1.5e-40	518	782
STKc_Nek1	cd08218	1.1e-42	518	783
STKc_Nek3	cd08219	4.1e-33	518	785
STKc_Nek8	cd08220	3e-38	518	788
STKc_Nek9	cd08221	9.8e-31	518	785
STKc_Nek4	cd08223	6.1e-37	518	783
STKc_Nek11	cd08222	3.8e-34	518	783
STKc_Nek5	cd08225	5.8e-37	518	788
STKc_Nek10	cd08528	6.6e-222	518	785
STKc_FA2-like	cd08529	5.5e-45	518	782
STKc_CNK2-like	cd08530	9.9e-37	518	782
PTKc_Axl_like	cd05035	5.3e-05	519	787
PTKc_Tyro3	cd05074	4.5e-05	519	787
PTKc_Srm_Brk	cd05148	2.7e-08	519	786
STKc_CMGC	cd05118	3.9e-15	519	791
STKc_PKN	cd05589	3.7e-08	519	871
STKc_MST1_2	cd06612	6e-14	519	776
STKc_MST4	cd06640	6.9e-09	519	812
STKc_MST3	cd06641	5.6e-09	519	809
STKc_CDK_like	cd07829	2e-17	519	778
STKc_MAK_like	cd07830	8.7e-12	519	791
STKc_CDK1_like	cd07835	1.6e-19	519	816
STKc_CDK4_6_like	cd07838	1.1e-14	519	774
STKc_CDK9_like	cd07840	6.6e-13	519	816
STKc_MOK	cd07831	1.1e-13	519	816
PTKc_Src_like	cd05034	8.1e-08	520	786
PTKc_Tec_like	cd05059	5.2e-11	520	784
PKc_MAPKK_Byr1_like	cd06620	1.2e-09	521	792
PTKc_Jak2_Jak3_rpt2	cd05081	9.1e-09	522	787
STKc_RSK_N	cd05582	1.8e-09	522	844
STKc_p70S6K	cd05584	3.2e-13	522	841
STKc_Rim15_like	cd05611	5.2e-05	522	907
PKc_MKK4	cd06616	6.8e-11	522	805
STKc_MEKK4	cd06626	7.6e-18	522	779
PTKc	cd00192	8.2e-13	523	784
PTKc_Ack_like	cd05040	5.8e-11	523	785
PTKc_Fes_like	cd05041	2.8e-12	523	785
PTKc_Aatyk	cd05042	0.00095	523	785
PTKc_c-ros	cd05044	9.2e-06	523	785
PTKc_Tie	cd05047	6.4e-05	523	788
PTKc_Met_Ron	cd05058	2.4e-07	523	789
PTKc_Syk_like	cd05060	6.4e-08	523	788
PTK_Jak1_rpt1	cd05077	0.00071	523	784
PTK_Jak2_Jak3_rpt1	cd05078	0.00053	523	777
PTKc_Fer	cd05085	4e-10	523	785
PTKc_Fes	cd05084	1.5e-09	523	785
PTKc_Syk	cd05116	5.5e-08	523	788
STKc_PKB	cd05571	1.4e-12	523	846
STKc_SGK	cd05575	5.4e-10	523	873
STKc_aPKC	cd05588	1.1e-07	523	845
STKc_nPKC_eta	cd05590	8.1e-09	523	845
STKc_nPKC_epsilon	cd05591	1.3e-09	523	845
STKc_nPKC_theta_delt	cd05592	3.4e-10	523	846
STKc_PKB_gamma	cd05593	1.6e-08	523	851
STKc_PKB_alpha	cd05594	1.9e-10	523	847
STKc_SGK1	cd05602	2.2e-09	523	852
STKc_SGK2	cd05603	3.2e-11	523	845
STKc_PKB_beta	cd05595	8.2e-09	523	852
STKc_nPKC_delta	cd05620	0.00038	523	846
STKc_nPKC_theta	cd05619	2.8e-08	523	846
STKc_SGK3	cd05604	1.9e-06	523	875
STKc_MEKK1	cd06630	3.6e-13	523	788
STKc_YSK4	cd06631	3.5e-14	523	787
PTKc_Zap-70	cd05115	6.4e-08	524	788
PKc	cd00180	3.1e-69	525	783
STKc_AGC	cd05123	7.3e-18	525	788
STKc_PKC	cd05570	8.3e-10	525	844
STKc_cGK_PKG	cd05572	4.6e-13	525	798
STKc_GRK	cd05577	2.3e-09	525	792
STKc_MAST_like	cd05579	7.7e-15	525	785
STKc_YPK1_like	cd05585	8.6e-10	525	843
STKc_Sck1_like	cd05586	3.4e-09	525	899
STKc_GRK7	cd05607	1e-06	525	813
STKc_aPKC_zeta	cd05617	1.2e-07	525	854
STKc_beta_ARK	cd05606	2.2e-08	525	808
STKc_aPKC_iota	cd05618	1.1e-05	525	854
STKc_GRK1	cd05608	8.9e-09	525	808
STKc_GRK3	cd05633	4.5e-06	525	809
STKc_MEKK1_plant	cd06632	1.3e-17	525	779
STKc_NDR_like	cd05599	4.2e-07	526	817
STKc_MAPKKK_Bck1_lik	cd06629	3.2e-11	526	776
PTKc_Csk_like	cd05039	6.7e-06	544	740
Pkinase	pfam00069	1e-66	519	783
Pkinase_Tyr	pfam07714	1.6e-16	519	783
TyrKc	smart00219	5.1e-15	519	783
STYKc	smart00221	6.1e-61	519	785
S_TKc	smart00220	1.7e-72	529	788
KIND	smart00750	1.5e-05	617	793

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040929	Polymorphism	p.ALA66VAL	N/A
Swiss-Prot	VAR_040933	Polymorphism	p.ASN659SER	N/A
Swiss-Prot	VAR_040931	Polymorphism	p.GLU379LYS	N/A
Swiss-Prot	VAR_040930	Polymorphism	p.GLY67SER	N/A
Swiss-Prot	VAR_040932	Polymorphism	p.LEU513SER	N/A
Swiss-Prot	VAR_040934	Polymorphism	p.LEU701VAL	N/A
Swiss-Prot	VAR_040928	Polymorphism	p.PHE50LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258