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Results for the Protein: Q92963
38258628

RIT1_HUMAN RecName: Full=GTP-binding protein Rit1; AltName: Full=Ras-like protein expressed in many tissues; AltName: Full=Ras-like without CAAX protein 1

Known Diseases associated with this Protein:
  NOONAN SYNDROME 8
  NOONAN SYNDROME 8 (NS8)
8
5
4
0
9
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

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 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

COG1100 - COG1100
Rab30 - cd04114
Rab9 - cd04116
Rnd3_RhoE_Rho8 - cd04172
Rab2 - cd01866
Rab8_Rab10_Rab13_lik - cd01867
small_GTPase - smart00010
RhoG - cd01875
M_R_Ras_like - cd04145
Rit_Rin_Ric - cd04141
Rab33B_Rab33A - cd04115
Rab35 - cd04110
RhoBTB - cd01873
ARHI_like - cd04140
RheB - cd04137
Rap1 - cd04175
RSR1 - cd04177
Rap_like - cd04136
Rap2 - cd04176
H_N_K_Ras_like - cd04138
Rab5_related - cd01860
Rab3 - cd01865
Rop_like - cd04133
RhoA_like - cd01870
Rac1_like - cd01871
Rnd - cd04131
Rho2 - cd04129
Cdc42 - cd01874
Rab20 - cd04126
- cd04125
RabL2 - cd04124
Rab12 - cd04120
RJL - cd04119
Wrch_1 - cd04130
Rab14 - cd04122
Rab21 - cd04123
RRP22 - cd04142
RAS - smart00173
RAB - smart00175
Rab24 - cd04118
RGK - cd04148
Rhes_like - cd04143
Tc10 - cd04135
RalA_RalB - cd04139
Rho4_like - cd04132
Rab23_like - cd04106
Rab7 - cd01862
Rab18 - cd01863
Rab19 - cd01864
Rab6 - cd01861
Rab15 - cd04117
Ran - cd00877
Rho - cd00157
Rab - cd00154
Rab1_Ypt1 - cd01869
Rab11_like - cd01868
Rab39 - cd04111
Rab26 - cd04112
Rab4 - cd04113
Rab28 - cd04109
Rab36_Rab34 - cd04108
RabL4 - cd04101
Rab32_Rab38 - cd04107
Centaurin_gamma - cd04103
Arl10_like - cd04159
Ras - pfam00071
Miro - pfam08477
Ras_dva - cd04147
Ras - cd00876
Miro1 - cd01893
Arf_Arl - cd00878
RERG_RasL11_like - cd04146
Rab27A - cd04127
Rho3 - cd04134
Ras2 - cd04144
RHO - smart00174
Ras_like_GTPase - cd00882
RAN - smart00176


Swiss-Prot Protein: Q92963
Identical to: NP_008843
   Default View:
















































































Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
COG1100COG11001.3e-3615216
Rab30cd041142.3e-1216183
Rnd3_RhoE_Rho8cd041726.7e-0517185
Rab9cd041165.6e-2017182
Rab2cd018662.9e-3118185
Rab8_Rab10_Rab13_likcd018671.8e-3519185
RhoGcd018751.4e-1119192
RhoBTBcd018730.0002220182
Rab35cd041107.7e-2020217
Rab33B_Rab33Acd041151.6e-1220197
Rit_Rin_Riccd041412.8e-12220191
M_R_Ras_likecd041456.9e-7620183
Rab5_relatedcd018605.3e-1521183
Rab3cd018654.4e-2121185
RhoA_likecd018701.5e-1821183
Rac1_likecd018711.6e-1721182
Cdc42cd018744.2e-1421182
Rho2cd041292e-1021218
Rndcd041319.7e-0621184
Rop_likecd041331.3e-0621208
Rap_likecd041361.1e-7921183
RheBcd041371.2e-4421204
H_N_K_Ras_likecd041387.8e-7521183
ARHI_likecd041406.1e-3821183
Rap1cd041754.4e-6621184
Rap2cd041765.5e-6521183
RSR1cd041774.9e-4621219
Rabcd001541.8e-4322180
Rhocd001571.4e-2222181
Rancd008773.7e-1122190
Rab6cd018612.6e-1622182
Rab7cd018622e-1322188
Rab18cd018631.5e-2322182
Rab19cd018641.1e-1022182
Rab11_likecd018686.6e-1722183
Rab1_Ypt1cd018696.6e-3222185
RabL4cd041014.4e-0722183
Centaurin_gammacd041030.0001122182
Rab23_likecd041061.3e-1722182
Rab32_Rab38cd041071.4e-0822218
Rab28cd041093.8e-0722219
Rab36_Rab34cd041089.7e-0522219
Rab39cd041114.3e-0922219
Rab26cd041121.6e-0822210
Rab4cd041131.1e-1322182
Rab15cd041174.4e-2022182
Rab24cd041181.5e-0822219
RJLcd041197.2e-1022184
Rab12cd041205.7e-0622217
Rab14cd041221.6e-2222185
Rab21cd041234.7e-2822183
RabL2cd041241.9e-0622185
cd041253.4e-0922213
Rab20cd041266.2e-0722207
Wrch_1cd041302.1e-1422182
Rho4_likecd041322.8e-1122219
Tc10cd041353.6e-1222179
RalA_RalBcd041394.6e-6222185
RRP22cd041424.9e-0822193
Rhes_likecd041432.9e-1222219
RGKcd041487.3e-1422219
Rascd008762.8e-9523182
Arf_Arlcd008788.8e-0523184
Miro1cd018932e-0623177
Rab27Acd041274.8e-1123186
Rho3cd041341.5e-0623193
Ras2cd041445.9e-5423219
RERG_RasL11_likecd041462.2e-5223184
Ras_dvacd041471.3e-1423219
Arl10_likecd041592e-0523181
Ras_like_GTPasecd008823.4e-5326180
Raspfam000711.2e-7223184
small_GTPasesmart000101.3e-4419186
RASsmart001736.8e-11222185
RABsmart001756e-3222185
Miropfam084771e-1423137
RHOsmart001741.3e-1124185
RANsmart001766.6e-0627217

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_070150Diseasep.ALA57GLYNoonan syndrome 8 (NS8)
Swiss-ProtVAR_070151Diseasep.GLU81GLYNoonan syndrome 8 (NS8)
Swiss-ProtVAR_070157Diseasep.GLY95ALANoonan syndrome 8 (NS8)
Swiss-ProtVAR_070156Polymorphismp.MET90ILEN/A
Swiss-ProtVAR_070152Diseasep.PHE82LEUNoonan syndrome 8 (NS8)
Swiss-ProtVAR_070153Polymorphismp.PHE82VALN/A
Swiss-ProtVAR_070149Polymorphismp.SER35THRN/A
Swiss-ProtVAR_070154Polymorphismp.THR83PRON/A
Swiss-ProtVAR_070155Polymorphismp.TYR89HISN/A
OMIM609591.0001 Diseasep.ALA40GLYNOONAN SYNDROME 8
OMIM609591.0002 Diseasep.GLU64GLYNOONAN SYNDROME 8
OMIM609591.0004 Diseasep.GLY78ALANOONAN SYNDROME 8
OMIM609591.0003 Diseasep.PHE65LEUNOONAN SYNDROME 8



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