Results for the protein: NP

Results for the Protein: NP_060042

40018631

2872

MKNK2

NCBI

MAP kinase-interacting serine/threonine-protein kinase 2 isoform 1 [Homo sapiens]

			0 1 0 1 0

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RefSeq Protein: NP_060042

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK	cd05596	6.1e-06	47	414
STKc_ROCK2	cd05621	7.7e-06	47	402
STKc_TAO1	cd06635	3.6e-05	57	408
PTKc_FAK	cd05056	0.00057	58	349
STKc_JNK1	cd07875	2.9e-06	60	414
STKc_JNK2	cd07876	1e-06	60	413
STKc_TAO3	cd06633	0.00033	61	384
STKc_PAK1	cd06654	2.9e-07	61	392
STKc_MAP4K4_6	cd06636	2.3e-05	62	368
STKc_PAK2	cd06655	1.4e-07	62	393
STKc_PAK3	cd06656	6.4e-08	62	389
STKc_JNK	cd07850	4.3e-07	62	410
STKc_PAK	cd06614	1.4e-17	64	382
STKc_myosinIIIB	cd06639	1e-06	64	369
STKc_p38delta_MAPK13	cd07879	0.0002	64	410
STKc_PAK4	cd06657	4.3e-07	65	387
STKc_PAK5	cd06658	8.3e-07	65	385
STKc_PAK6	cd06659	1.5e-09	65	390
STKc_p38alpha_MAPK14	cd07877	2.3e-05	65	403
STKc_myosinIIIA	cd06638	9.1e-08	67	368
STKc_PAK_I	cd06647	6.5e-08	67	390
STKc_JNK3	cd07874	5.3e-06	67	413
STKc_TAO2	cd06634	0.00014	68	403
PKc_MKK7	cd06618	3.9e-08	69	385
STKc_p38gamma_MAPK12	cd07880	1.1e-06	69	409
STKc_p38beta_MAPK11	cd07878	7.2e-06	70	409
PTKc_EGFR_like	cd05057	0.00071	71	360
STKc_p38	cd07851	6.8e-09	71	403
STKc_TAO	cd06607	3.5e-06	72	393
STKc_TNIK	cd06637	7.1e-07	72	368
STKc_PAK_II	cd06648	1.5e-11	72	381
STKc_MAP4K5	cd06646	7.7e-08	73	367
STKc_CDK9	cd07865	1.2e-06	73	368
STKc_STK10_LOK	cd06644	1.8e-07	74	388
STKc_MAP4K3	cd06645	1.7e-08	74	367
STKc_MAPK4_6	cd07854	0.00023	75	389
STKc_CDK12	cd07864	5.3e-10	75	368
STKc_ROCK_NDR_like	cd05573	9.5e-12	77	414
STKc_phototropin_lik	cd05574	1.1e-13	77	390
STKc_PCTAIRE_like	cd07844	9.7e-08	77	368
STKc_CDK10	cd07845	4.2e-10	77	378
STKc_Sty1_Hog1	cd07856	3.6e-08	77	404
STKc_PCTAIRE3	cd07871	6.3e-07	77	368
STKc_PCTAIRE2	cd07872	3.4e-06	77	387
STKc_PCTAIRE1	cd07873	6.9e-06	77	381
PTKc_Abl	cd05052	0.00026	78	345
PTKc_Tie2	cd05088	0.00034	78	373
PTKc_TrkA	cd05092	0.0009	78	351
PTKc_Itk	cd05112	0.00023	78	345
PKc_MAPKK_Byr1_like	cd06620	4.7e-06	78	387
STKc_ASK	cd06624	4.9e-08	78	368
STKc_ERK5	cd07855	8.4e-08	78	389
STKc_TEY_MAPK_plant	cd07858	2.3e-08	78	410
STKc_CDK4	cd07863	6.3e-06	78	368
PTKc_Src_like	cd05034	8.7e-05	79	329
PTKc_Jak2_Jak3_rpt2	cd05081	0.00045	79	361
PTKc_Tie1	cd05089	6.7e-05	79	369
STKc_MST1_2	cd06612	3.6e-13	79	368
STKc_MAP4K3_like	cd06613	7.5e-13	79	367
PKc_MKK4	cd06616	6.1e-07	79	383
STKc_ERK1_2_like	cd07849	4.2e-08	79	407
STKc_BUR1	cd07866	6.2e-08	79	368
STKc_DMPK_like	cd05597	7.6e-08	80	409
STKc_MAST	cd05609	8.4e-08	80	413
STKc_MRCK_alpha	cd05623	3e-07	80	410
STKc_MRCK_beta	cd05624	9.2e-07	80	411
STKc_NDR2	cd05627	4.9e-05	80	414
STKc_NDR1	cd05628	1.1e-06	80	414
PKc_MAPKK	cd06605	6.1e-09	80	373
PKc_MEK	cd06615	1.3e-05	80	377
PKc_MKK3_6	cd06617	5.3e-06	80	387
PKc_MKK5	cd06619	5.3e-05	80	390
PKc_MAPKK_Pek1_like	cd06621	2.4e-07	80	386
PKc_MAPKK_PBS2_like	cd06622	5.3e-06	80	389
PKc_MAPKK_plant_like	cd06623	1.8e-15	80	373
STKc_MST4	cd06640	3.1e-05	80	387
STKc_MST3	cd06641	0.00011	80	387
STKc_STK25-YSK1	cd06642	1.4e-05	80	387
STKc_SLK	cd06643	7.8e-08	80	386
STKc_MEKK2	cd06652	1.3e-05	80	369
STKc_SLK_like	cd06611	1.6e-10	80	385
STKc_PFTAIRE1	cd07869	0.00072	80	380
STKc_PFTAIRE2	cd07870	3.4e-06	80	368
SPS1	COG0515	8e-37	80	414
PTKc_Frk_like	cd05068	4.3e-05	81	344
STKc_MSK_N	cd05583	1.2e-11	81	383
STKc_cPKC	cd05587	4.9e-08	81	413
STKc_PRKX_like	cd05612	2.2e-11	81	394
STKc_cPKC_beta	cd05616	1.2e-06	81	413
STKc_myosinIII_like	cd06608	8.9e-10	81	368
STKc_OSR1_SPAK	cd06610	1e-13	81	368
STKc_MST3_like	cd06609	1.6e-13	81	387
STKc_MEKK3	cd06651	3.4e-09	81	370
STKc_MEKK3_like_1	cd06653	1.1e-05	81	368
STKc_NAK1_like	cd06917	8.9e-11	81	387
STKc_CDKL	cd07833	2.3e-12	81	368
STKc_CdkB_plant	cd07837	1.3e-10	81	369
STKc_CDKL2_3	cd07846	5.8e-11	81	368
STKc_CDKL1_4	cd07847	2.3e-11	81	368
STKc_Nek6_Nek7	cd08224	5.2e-07	81	371
PKc_STE	cd05122	3.5e-27	82	367
STKc_Yank1	cd05578	2.5e-17	82	368
STKc_MSK1_N	cd05613	2.6e-09	82	383
STKc_LATS1	cd05625	0.00066	82	414
STKc_MAPKKK	cd06606	1.2e-22	82	368
STKc_Cdc7_like	cd06627	6.4e-18	82	368
STKc_MAPKKK_Bck1_lik	cd06629	8.2e-11	82	368
STKc_CCRK	cd07832	3.7e-14	82	369
STKc_MAPK	cd07834	1.7e-11	82	414
STKc_Pho85	cd07836	3.4e-10	82	368
STKc_CDK8_like	cd07842	1.8e-06	82	368
STKc_MPK1	cd07857	3.9e-09	82	386
STKc_CDK2_3	cd07860	6.3e-06	82	368
STKc_TDY_MAPK_plant	cd07859	4.1e-09	82	396
STKc_CDC2L6	cd07867	0.00025	82	368
STKc_CDK8	cd07868	0.00051	82	368
STKc_Nek	cd08215	4e-17	82	368
STKc_Nek3	cd08219	8.8e-10	82	368
STKc_Nek4	cd08223	1e-05	82	368
STKc_Nek5	cd08225	2e-05	82	368
STKc_Nek10	cd08528	2e-06	82	368
STKc_CNK2-like	cd08530	3.4e-08	82	368
PTKc_ALK_LTK	cd05036	1.4e-05	83	324
STKc_MSK2_N	cd05614	6.6e-09	83	403
STKc_cPKC_alpha	cd05615	1.9e-08	83	413
STKc_MAPKKK_Byr2_lik	cd06628	2.8e-11	83	368
STKc_CDK_like	cd07829	6.7e-14	83	368
STKc_MAK_like	cd07830	1.8e-12	83	368
STKc_MOK	cd07831	4.2e-12	83	368
STKc_CDK1_like	cd07835	8.1e-09	83	368
STKc_CDK4_6_like	cd07838	7.1e-07	83	368
STKc_CDK9_like	cd07840	3.4e-13	83	368
STKc_CDK1_euk	cd07861	3.8e-15	83	368
STKc_Nek1	cd08218	1.7e-06	83	368
STKc_Nek11	cd08222	0.0001	83	368
STKc_Nek7	cd08229	2.9e-05	83	371
STKc_FA2-like	cd08529	5.5e-07	83	368
PTKc_Trk	cd05049	1.8e-05	84	324
STKc_MEKK4	cd06626	1.8e-12	84	368
STKc_NLK	cd07853	3.8e-06	84	409
STKc_CDK6	cd07862	0.00061	84	368
STKc_CDK7	cd07841	1.1e-11	85	378
STKc_Nek6	cd08228	1.3e-05	85	371
STKc_GRK4_like	cd05605	1.3e-09	86	399
STKc_GRK6	cd05630	7.1e-07	86	380
STKc_GRK5	cd05632	2.7e-08	86	396
STKc_MEKK3_like	cd06625	2.2e-12	86	368
STKc_YSK4	cd06631	1.4e-08	86	368
STKc_PKA	cd05580	3.7e-15	87	412
STKc_RSK_N	cd05582	2e-07	87	413
STKc_PDK1	cd05581	5.5e-31	87	368
STKc_p70S6K	cd05584	1.5e-08	87	414
STKc_NDR_like	cd05599	8.1e-09	87	391
STKc_CRIK	cd05601	5.1e-10	87	414
PTKc	cd00192	2.2e-07	88	367
PTKc_Ack_like	cd05040	6.3e-07	88	331
PTKc_Fes_like	cd05041	2.7e-05	88	328
PTKc_Tie	cd05047	0.00051	88	346
PTKc_Syk_like	cd05060	0.00092	88	331
PTKc_Fes	cd05084	0.00018	88	346
PTKc_Fer	cd05085	2.3e-05	88	346
STKc_CMGC	cd05118	2.4e-16	88	368
STKc_PKC	cd05570	4.3e-14	88	414
STKc_SGK	cd05575	3.3e-09	88	414
STKc_PKB	cd05571	6.1e-11	88	414
STKc_aPKC	cd05588	1.1e-08	88	413
STKc_nPKC_eta	cd05590	5.4e-08	88	414
STKc_nPKC_epsilon	cd05591	1.3e-08	88	414
STKc_nPKC_theta_delt	cd05592	2.1e-08	88	414
STKc_PKB_alpha	cd05594	2.7e-09	88	412
STKc_PKB_beta	cd05595	3.1e-07	88	414
STKc_SGK1	cd05602	3.8e-08	88	414
STKc_LATS	cd05598	1.3e-06	88	414
STKc_SGK2	cd05603	7e-09	88	414
STKc_SGK3	cd05604	6.8e-06	88	414
STKc_PKB_gamma	cd05593	2.7e-07	88	414
STKc_nPKC_theta	cd05619	1.3e-08	88	414
STKc_nPKC_delta	cd05620	0.00015	88	414
STKc_aPKC_iota	cd05618	1.1e-06	88	413
STKc_aPKC_zeta	cd05617	1.1e-07	88	413
STKc_MEKK1	cd06630	1.6e-06	88	369
STKc_CDK5	cd07839	1.4e-06	88	368
STKc_CDKL5	cd07848	8.3e-05	88	368
STKc_Nek2	cd08217	2.6e-08	88	368
STKc_PKN	cd05589	1.7e-08	89	413
STKc_beta_ARK	cd05606	1e-07	89	394
STKc_GRK4	cd05631	3e-07	89	385
STKc_GRK3	cd05633	2.9e-06	89	395
STKc_MEKK1_plant	cd06632	5.9e-10	89	368
STKc_Nek8	cd08220	1.9e-08	89	368
STKc_Nek9	cd08221	4.5e-07	89	368
PKc	cd00180	1.1e-71	90	366
STKc_AGC	cd05123	1.4e-31	90	368
STKc_cGK_PKG	cd05572	1.9e-14	90	375
STKc_GRK	cd05577	1.6e-09	90	384
STKc_MAST_like	cd05579	2.3e-18	90	376
STKc_YPK1_like	cd05585	6.7e-09	90	412
STKc_Sck1_like	cd05586	1.6e-05	90	412
STKc_GRK7	cd05607	9.3e-05	90	398
STKc_GRK1	cd05608	2.1e-08	90	384
STKc_Rim15_like	cd05611	4e-06	93	374
STKc_CDC2L1	cd07843	2.9e-09	97	368
STKc_MAPK15	cd07852	7.8e-12	102	403
STKc_Sid2p_Dbf2p	cd05600	5.9e-05	103	413
Pkinase	pfam00069	8.5e-74	83	368
Pkinase_Tyr	pfam07714	4.2e-11	83	366
STYKc	smart00221	1.5e-71	83	368
TyrKc	smart00219	7.4e-10	84	366
S_TKc	smart00220	1.6e-84	94	368

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs3746101	Polymorphism	p.GLN10LYS	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258