Results for the protein: O75716

Results for the Protein: O75716

46577677

8576

STK16

NCBI, UniProt

STK16_HUMAN RecName: Full=Serine/threonine-protein kinase 16; AltName: Full=Myristoylated and palmitoylated serine/threonine-protein kinase; Short=MPSK; AltName: Full=Protein kinase PKL12; AltName: Full=TGF-beta-stimulated factor 1; Short=TSF-1; AltName: Full=Tyrosine-protein kinase STK16; AltName: Full=hPSK

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Swiss-Prot Protein: O75716

Identical to: NP_001008910

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_PAK5	cd06658	3.6e-06	1	304
STKc_PAK6	cd06659	1.3e-08	1	305
STKc_PAK_I	cd06647	0.0001	2	304
STKc_PAK2	cd06655	0.00027	2	297
STKc_PAK3	cd06656	9.6e-05	2	298
STKc_PAK4	cd06657	6.9e-06	2	304
STKc_PAK	cd06614	8e-11	3	305
STKc_myosinIIIB	cd06639	2.9e-05	3	293
STKc_myosinIIIA	cd06638	1.7e-06	6	293
STKc_MAP4K3	cd06645	9.2e-06	8	291
PTKc_EphR_A2	cd05063	0.00018	9	294
STKc_ASK	cd06624	8.8e-05	9	292
STKc_TNIK	cd06637	2.2e-05	9	292
STKc_TAO2	cd06634	0.00016	10	305
STKc_MAP4K4_6	cd06636	9.3e-05	10	292
STKc_STK10_LOK	cd06644	0.0002	10	301
STKc_PAK_II	cd06648	1.2e-08	10	303
PKc_MKK7	cd06618	4.8e-05	11	305
STKc_CDK12	cd07864	1.1e-07	11	298
PTKc_Ror	cd05048	0.0003	12	293
PTKc_EGFR_like	cd05057	0.00062	12	304
STKc_MAP4K5	cd06646	6.8e-06	12	291
STKc_CDK10	cd07845	3e-05	12	298
STKc_p38	cd07851	0.001	12	295
STKc_CDK9	cd07865	6.6e-06	12	285
PTKc_ALK_LTK	cd05036	0.00012	13	292
PTKc_Csk_like	cd05039	0.00075	13	293
PTKc_FAK	cd05056	8.2e-06	13	298
PTKc_Csk	cd05082	7e-05	13	293
PTKc_Chk	cd05083	0.0001	13	293
PTKc_Trk	cd05049	3.2e-07	14	292
STKc_SLK	cd06643	8.9e-05	14	292
PTKc_EphR	cd05033	3.3e-06	15	294
PTKc_Src_like	cd05034	7e-06	15	293
PTKc_Musk	cd05050	0.00025	15	292
PTKc_Abl	cd05052	8.7e-05	15	294
PTKc_Tec_like	cd05059	4.5e-05	15	291
PTKc_EphR_B	cd05065	9e-07	15	294
PTKc_EphR_A	cd05066	0.00015	15	294
PTKc_Lck_Blk	cd05067	0.00029	15	293
PTKc_Frk_like	cd05068	6.6e-10	15	293
PTKc_Yes	cd05069	0.00014	15	293
PTKc_Fyn_Yrk	cd05070	0.00027	15	293
PTKc_Lyn	cd05072	6.9e-05	15	293
PTKc_Hck	cd05073	0.00041	15	293
PTKc_TrkB	cd05093	0.00071	15	302
PTKc_EphR_A10	cd05064	0.00035	15	294
PTKc_Itk	cd05112	6e-06	15	291
PTKc_Btk_Bmx	cd05113	4.2e-07	15	291
PTKc_Tec_Rlk	cd05114	4.6e-06	15	291
STKc_MAPK15	cd07852	0.00089	15	305
STKc_MAP4K3_like	cd06613	5e-09	16	291
PKc_MAPKK_plant_like	cd06623	4.1e-09	16	298
STKc_PCTAIRE_like	cd07844	0.0001	16	305
PTKc_Jak_rpt2	cd05038	8e-06	17	294
PTKc_Jak1_rpt2	cd05079	0.00011	17	294
PTKc_Tyk2_rpt2	cd05080	3.3e-05	17	295
PTKc_Jak2_Jak3_rpt2	cd05081	3e-06	17	294
STKc_myosinIII_like	cd06608	3.4e-08	17	286
STKc_SLK_like	cd06611	5.6e-06	17	291
STKc_ERK1_2_like	cd07849	1.8e-05	17	305
STKc_BUR1	cd07866	6.1e-09	17	298
PTKc_Srm_Brk	cd05148	0.00012	18	293
STKc_phototropin_lik	cd05574	1.3e-09	18	291
STKc_ROCK_NDR_like	cd05573	2.6e-06	18	304
STKc_PKA	cd05580	3e-05	18	305
STKc_PDK1	cd05581	8.5e-12	18	286
STKc_CRIK	cd05601	9.8e-06	18	305
STKc_PRKX_like	cd05612	9.2e-05	18	302
PKc_MAPKK	cd06605	1.1e-05	18	292
STKc_MST3_like	cd06609	1.2e-05	18	294
STKc_OSR1_SPAK	cd06610	4.6e-09	18	293
STKc_MST1_2	cd06612	1e-07	18	283
PKc_MKK3_6	cd06617	8e-06	18	292
PKc_MAPKK_Pek1_like	cd06621	0.0009	18	296
STKc_CDKL	cd07833	1.3e-06	18	288
STKc_CdkB_plant	cd07837	1.7e-06	18	299
STKc_CDKL2_3	cd07846	3.4e-08	18	293
STKc_CDKL1_4	cd07847	5.5e-06	18	292
STKc_CDC2L1	cd07843	4.7e-05	18	283
STKc_CDK6	cd07862	5.5e-05	18	292
STKc_PCTAIRE3	cd07871	8.5e-05	18	292
STKc_Nek6_Nek7	cd08224	5.8e-09	18	295
STKc_Nek6	cd08228	9.5e-08	18	295
STKc_Nek7	cd08229	2e-09	18	295
SPS1	COG0515	3.8e-19	18	305
PKc_STE	cd05122	1.5e-12	19	291
STKc_Yank1	cd05578	1.2e-09	19	293
STKc_MSK_N	cd05583	5.6e-05	19	301
STKc_MSK1_N	cd05613	0.00026	19	301
STKc_GRK6	cd05630	2.8e-05	19	301
STKc_GRK4	cd05631	3.8e-05	19	301
STKc_GRK5	cd05632	5e-06	19	301
STKc_GRK4_like	cd05605	1.8e-06	19	301
STKc_MAPKKK	cd06606	4.6e-14	19	292
STKc_Cdc7_like	cd06627	1.1e-07	19	288
STKc_MAPKKK_Byr2_lik	cd06628	4.4e-06	19	292
STKc_MEKK3	cd06651	3e-05	19	294
STKc_CCRK	cd07832	5.5e-08	19	297
STKc_MAPK	cd07834	4.9e-06	19	305
STKc_Pho85	cd07836	0.00022	19	304
STKc_CDK5	cd07839	7.7e-06	19	298
STKc_CDK7	cd07841	6.9e-09	19	291
STKc_CDK8_like	cd07842	0.00018	19	298
STKc_MPK1	cd07857	0.00058	19	305
STKc_CDK2_3	cd07860	0.00036	19	292
STKc_CDK1_euk	cd07861	0.00075	19	298
STKc_TDY_MAPK_plant	cd07859	0.00044	19	302
STKc_CDK4	cd07863	3.5e-07	19	298
STKc_Nek	cd08215	2e-17	19	293
STKc_Nek2	cd08217	2.4e-10	19	292
STKc_Nek1	cd08218	1.1e-16	19	292
STKc_Nek3	cd08219	4.9e-12	19	292
STKc_Nek8	cd08220	9.4e-08	19	292
STKc_Nek9	cd08221	1.8e-07	19	292
STKc_Nek11	cd08222	6.3e-08	19	292
STKc_Nek4	cd08223	2.2e-08	19	292
STKc_Nek5	cd08225	1.3e-11	19	292
STKc_Nek10	cd08528	4e-08	19	292
STKc_FA2-like	cd08529	1.2e-10	19	293
STKc_CNK2-like	cd08530	4.5e-12	19	293
PTKc_Tyro3	cd05074	3.5e-06	20	294
STKc_CMGC	cd05118	1.9e-12	20	286
STKc_CDK_like	cd07829	4.1e-10	20	290
STKc_MAK_like	cd07830	3.4e-06	20	286
STKc_CDK1_like	cd07835	6.5e-05	20	298
STKc_CDK4_6_like	cd07838	2.1e-06	20	285
STKc_CDK9_like	cd07840	1.7e-08	20	286
STKc_MOK	cd07831	3.1e-10	20	298
PTKc_Axl_like	cd05035	6e-06	21	294
PTKc_Axl	cd05075	3.8e-05	21	294
STKc_CDC2L6	cd07867	0.001	21	298
STKc_CDK8	cd07868	0.00043	21	298
STKc_RSK_N	cd05582	0.00027	23	305
PTKc	cd00192	3e-09	24	291
PTKc_Ack_like	cd05040	0.00086	24	292
PTKc_Fes_like	cd05041	9.4e-07	24	292
PTKc_Met_Ron	cd05058	2.4e-05	24	296
PTKc_Syk_like	cd05060	0.00017	24	292
PTKc_Fes	cd05084	2.1e-05	24	292
PTKc_Fer	cd05085	0.00026	24	292
PTKc_Syk	cd05116	1.2e-05	24	295
STKc_MEKK4	cd06626	3.4e-09	24	292
STKc_YSK4	cd06631	1.1e-05	24	290
STKc_MEKK1_plant	cd06632	9.5e-07	24	288
STKc_MEKK1	cd06630	5.9e-06	24	289
PTKc_Zap-70	cd05115	3.8e-05	25	295
PKc	cd00180	1.3e-66	26	290
STKc_AGC	cd05123	1.4e-11	26	286
STKc_cGK_PKG	cd05572	1.1e-06	26	280
STKc_GRK	cd05577	5.6e-07	26	299
STKc_MAST_like	cd05579	3.5e-06	26	283
STKc_beta_ARK	cd05606	0.00023	26	296
STKc_GRK7	cd05607	0.00047	26	300
STKc_GRK1	cd05608	9.4e-07	26	302
STKc_MEKK3_like	cd06625	2.9e-06	26	292
STKc_MAPKKK_Bck1_lik	cd06629	5.2e-06	27	292
PK_STRAD	cd08216	0.00019	31	295
Pkinase	pfam00069	3.2e-37	20	290
Pkinase_Tyr	pfam07714	7.4e-13	20	290
TyrKc	smart00219	1.3e-10	20	290
STYKc	smart00221	2.9e-35	20	292
S_TKc	smart00220	1.5e-30	30	293
KIND	smart00750	0.0007	104	300

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041143	Polymorphism	p.ARG266TRP	N/A
Swiss-Prot	VAR_041141	Polymorphism	p.GLU55LYS	N/A
Swiss-Prot	VAR_041140	Polymorphism	p.HIS41ARG	N/A
Swiss-Prot	VAR_041142	Polymorphism	p.ILE77VAL	N/A
Swiss-Prot	VAR_041144	Polymorphism	p.PRO277LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258