Results for the protein: P36896

Results for the Protein: P36896

547775

91

ACVR1B

NCBI, UniProt

ACV1B_HUMAN RecName: Full=Activin receptor type-1B; AltName: Full=Activin receptor type IB; Short=ACTR-IB; AltName: Full=Activin receptor-like kinase 4; Short=ALK-4; AltName: Full=Serine/threonine-protein kinase receptor R2; Short=SKR2; Flags: Precursor

			0 2 0 0 2

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Swiss-Prot Protein: P36896

Identical to: NP_004293

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_MAP4K4_6	cd06636	8.3e-05	190	478
PTKc_FGFR1	cd05098	0.00013	191	501
STKc_TAO2	cd06634	0.00068	191	497
PTKc_FGFR2	cd05101	0.00047	192	502
STKc_PAK_II	cd06648	0.0009	193	503
STKc_CDK9	cd07865	1.1e-06	194	478
PTKc_FGFR	cd05053	2.5e-05	195	499
PTKc_FGFR4	cd05099	0.00011	195	505
STKc_myosinIIIA	cd06638	3.3e-05	195	465
PTKc_EGFR_like	cd05057	0.00015	196	500
STKc_PAK	cd06614	6.3e-09	196	498
PTK_Ryk	cd05043	0.00087	197	466
PTKc_Jak1_rpt2	cd05079	0.0002	198	498
PTKc_TrkA	cd05092	4.7e-05	198	487
STKc_MAP4K3	cd06645	0.00023	198	490
STKc_MAP4K5	cd06646	2.8e-05	198	495
STKc_ASK	cd06624	0.00039	198	496
STKc_CDK12	cd07864	4.8e-05	198	488
STKc_TNIK	cd06637	9.7e-06	200	478
PTKc_ALK_LTK	cd05036	3.7e-06	201	496
PTKc_Ror	cd05048	8.7e-06	201	497
PTKc_Trk	cd05049	3.6e-08	201	496
PTKc_FAK	cd05056	3e-06	201	502
PTKc_EphR_A2	cd05063	0.00011	201	498
PTKc_EphR_A10	cd05064	0.00024	201	498
PTKc_Frk_like	cd05068	4.5e-11	201	497
PTKc_Lyn	cd05072	2.7e-05	201	497
PTKc_Csk	cd05082	6.7e-08	201	497
PTKc_Ror2	cd05091	0.00062	201	497
PTKc_TrkB	cd05093	0.00062	201	502
PTKc_DDR2	cd05095	8.2e-05	201	496
PTKc_EphR	cd05033	3.5e-09	202	498
PTKc_Musk	cd05050	1.2e-05	202	496
PTKc_Abl	cd05052	1.4e-06	202	498
PTKc_IGF-1R	cd05062	0.00055	202	496
PTKc_Lck_Blk	cd05067	1.2e-05	202	497
PTKc_InsR	cd05061	0.00082	202	505
PTKc_Fyn_Yrk	cd05070	4.7e-05	202	473
PTKc_Src	cd05071	2.2e-05	202	499
PTKc_Yes	cd05069	3.2e-06	202	497
PTKc_Hck	cd05073	5.4e-05	202	497
PTKc_Itk	cd05112	2.5e-06	202	495
PTKc_Btk_Bmx	cd05113	4.5e-07	202	495
PTKc_Tec_Rlk	cd05114	5.1e-05	202	495
STKc_MST4	cd06640	0.00042	202	489
STKc_MST3	cd06641	0.00015	202	467
STKc_STK25-YSK1	cd06642	4.9e-05	202	486
STKc_CDK10	cd07845	2.5e-05	202	503
PTKc_InsR_like	cd05032	4.7e-06	203	496
STKc_MST1_2	cd06612	1.1e-09	203	456
STKc_MAP4K3_like	cd06613	4.4e-08	203	458
PTKc_Jak_rpt2	cd05038	4.5e-05	204	498
PTKc_Csk_like	cd05039	2.3e-08	204	429
PTKc_Tec_like	cd05059	3.3e-07	204	447
PTKc_EphR_B	cd05065	1.4e-05	204	498
PTKc_EphR_A	cd05066	5.5e-05	204	473
PTKc_Jak2_Jak3_rpt2	cd05081	7.3e-05	204	498
PTK_HER3	cd05111	0.00062	204	491
STKc_Nek6_Nek7	cd08224	3.6e-06	204	471
STKc_Nek7	cd08229	2.6e-05	204	468
PTKc_Src_like	cd05034	1.2e-09	205	497
PTKc_Tyk2_rpt2	cd05080	1.9e-05	205	499
PTKc_Chk	cd05083	6.8e-06	205	497
PTKc_Tie2	cd05088	4.7e-05	205	499
STKc_PKA	cd05580	0.00024	205	463
STKc_PDK1	cd05581	1.7e-06	205	460
STKc_MST3_like	cd06609	2.5e-05	205	467
PKc_MKK3_6	cd06617	0.00012	205	487
PKc_MAPKK_Pek1_like	cd06621	0.00026	205	477
PKc_MAPKK_plant_like	cd06623	9e-05	205	495
STKc_CDKL1_4	cd07847	9.3e-05	205	496
STKc_Nek3	cd08219	0.0007	205	499
STKc_MAPKKK	cd06606	2.2e-12	206	478
STKc_Cdc7_like	cd06627	2.6e-09	206	456
STKc_MAPKKK_Byr2_lik	cd06628	0.00015	206	491
STKc_MAPKKK_Bck1_lik	cd06629	7.6e-06	206	487
STKc_CCRK	cd07832	5.5e-08	206	486
STKc_CDK7	cd07841	0.00034	206	498
STKc_CDK1_euk	cd07861	0.0009	206	505
STKc_Nek4	cd08223	0.0005	206	464
PTKc_Axl_like	cd05035	0.0005	207	498
PTKc_Tyro3	cd05074	0.00048	207	498
PKc_STE	cd05122	7.9e-11	208	487
STKc_CDK9_like	cd07840	0.00041	208	427
STKc_Nek	cd08215	1.5e-06	208	449
STKc_FA2-like	cd08529	4.3e-05	208	440
PTKc_Srm_Brk	cd05148	7.4e-09	209	497
STKc_Yank1	cd05578	5e-06	209	497
STKc_CRIK	cd05601	3.5e-05	209	505
STKc_myosinIII_like	cd06608	4.5e-07	209	460
STKc_OSR1_SPAK	cd06610	1.9e-06	209	493
STKc_MEKK3_like	cd06625	1.7e-05	209	465
STKc_MEKK4	cd06626	1.9e-07	209	494
STKc_CDK8_like	cd07842	0.00076	209	478
STKc_CNK2-like	cd08530	6.2e-05	209	499
PTKc_Aatyk	cd05042	1.7e-06	210	496
PTKc_Aatyk2	cd05086	0.00028	210	496
PKc_MAPKK	cd06605	2.1e-05	210	465
STKc_CDK_like	cd07829	1.3e-05	210	490
PTKc	cd00192	7.6e-11	211	495
PTKc_Ack_like	cd05040	5.2e-07	211	496
PTKc_c-ros	cd05044	0.00011	211	496
PTKc_Fes_like	cd05041	3.2e-08	211	496
PTKc_Tie	cd05047	0.0008	211	499
PTKc_Met_Ron	cd05058	0.00044	211	500
PTKc_Syk_like	cd05060	1.7e-05	211	499
PTKc_Fes	cd05084	7e-05	211	465
PTKc_Fer	cd05085	2.3e-05	211	496
PTKc_Aatyk1_Aatyk3	cd05087	0.00026	211	496
STKc_CMGC	cd05118	2.3e-07	211	488
STKc_YSK4	cd06631	0.00012	211	457
STKc_MEKK1_plant	cd06632	3.2e-06	211	490
STKc_NAK1_like	cd06917	2.7e-05	211	500
STKc_CdkB_plant	cd07837	9.7e-07	211	496
STKc_CDKL2_3	cd07846	0.00013	211	495
STKc_Nek8	cd08220	0.00088	211	465
STKc_beta_ARK	cd05606	4.1e-05	212	492
STKc_GRK3	cd05633	0.001	212	500
STKc_Nek9	cd08221	0.00015	212	468
PKc	cd00180	7.5e-53	213	494
PTKc_Zap-70	cd05115	0.00082	213	478
STKc_AGC	cd05123	1.9e-06	213	492
STKc_GRK	cd05577	2e-05	213	458
STKc_MAST_like	cd05579	0.00073	213	459
STKc_GRK7	cd05607	0.00037	213	480
STKc_GRK1	cd05608	0.00078	213	492
Activin_recp	pfam01064	1.6e-27	32	109
Pkinase	pfam00069	3e-59	207	494
TGF_beta_GS	pfam08515	4.1e-14	177	205
GS	smart00467	1.2e-14	177	207
Pkinase_Tyr	pfam07714	4.3e-15	207	494
TyrKc	smart00219	6.1e-13	207	494
STYKc	smart00221	1.4e-23	207	478
S_TKc	smart00220	3.9e-18	217	497

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_011716	Polymorphism	p.LEU408VAL	N/A
Swiss-Prot	VAR_041406	Polymorphism	p.PHE146LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258