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Results for the Protein: Q13546
60393639

RIPK1_HUMAN RecName: Full=Receptor-interacting serine/threonine-protein kinase 1; AltName: Full=Cell death protein RIP; AltName: Full=Receptor-interacting protein 1; Short=RIP-1; AltName: Full=Serine/threonine-protein kinase RIP
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Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

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Default View:

STKc_p38gamma_MAPK12 - cd07880
STKc_PAK6 - cd06659
STKc_TAO1 - cd06635
STKc_ROCK - cd05596
PTKc_FGFR1 - cd05098
STKc_TAO2 - cd06634
PTKc_FGFR2 - cd05101
STKc_PAK - cd06614
STKc_CDK9 - cd07865
PTKc_VEGFR2 - cd05103
STKc_MAP4K3 - cd06645
STKc_p38 - cd07851
STKc_TAO - cd06607
PKc_MKK7 - cd06618
STKc_ROCK2 - cd05621
PTKc_PDGFR - cd05055
PTKc_Lyn - cd05072
PTKc_DDR - cd05051
STKc_p38alpha_MAPK14 - cd07877
PTKc_FGFR4 - cd05099
PTKc_FGFR3 - cd05100
PTKc_Tie2 - cd05088
STKc_STK10_LOK - cd06644
PTKc_InsR - cd05061
PTKc_EphR_B - cd05065
PTKc_EGFR_like - cd05057
STKc_ASK - cd06624
PTK_Jak1_rpt1 - cd05077
PTKc_ALK_LTK - cd05036
STKc_MAP4K5 - cd06646
PTKc_HER4 - cd05110
PTKc_EGFR - cd05108
PTKc_HER2 - cd05109
PTKc_Ror - cd05048
PTKc_Ror1 - cd05090
PTKc_Frk_like - cd05068
PTKc_Ror2 - cd05091
STKc_TEY_MAPK_plant - cd07858
PTKc_Lck_Blk - cd05067
PTKc_Btk_Bmx - cd05113
PTKc_Csk - cd05082
PTK_Ryk - cd05043
PTKc_IGF-1R - cd05062
PTKc_Abl - cd05052
PTKc_InsR_like - cd05032
PTKc_FAK - cd05056
PTKc_Tec_like - cd05059
PTKc_DDR_like - cd05097
PTKc_DDR1 - cd05096
STKc_TNIK - cd06637
PKc_MEK1 - cd06650
PTKc_TrkC - cd05094
STKc_CDK12 - cd07864
PKc_MEK2 - cd06649
PTKc_Trk - cd05049
PTKc_TrkB - cd05093
PTK_CCK4 - cd05046
PTKc_Musk - cd05050
PTKc_EphR_A2 - cd05063
PTKc_TrkA - cd05092
PTKc_EphR_A10 - cd05064
PTKc_Tec_Rlk - cd05114
PKc_MKK4 - cd06616
PTK_HER3 - cd05111
STKc_SLK - cd06643
PKc_MAPKK_Byr1_like - cd06620
PTKc_Itk - cd05112
PTKc_EphR - cd05033
PTKc_EphR_A - cd05066
PTKc_FGFR - cd05053
PTKc_Fyn_Yrk - cd05070
PTKc_Chk - cd05083
STKc_PFTAIRE2 - cd07870
STKc_PCTAIRE3 - cd07871
STKc_PCTAIRE_like - cd07844
STKc_MAP4K3_like - cd06613
PTKc_Hck - cd05073
PTKc_Yes - cd05069
PTKc_Jak_rpt2 - cd05038
PTKc_Src - cd05071
STKc_ERK1_2_like - cd07849
STKc_MAPK4_6 - cd07854
STKc_Nek10 - cd08528
STKc_MEKK3_like_1 - cd06653
STKc_BUR1 - cd07866
STKc_MEKK2 - cd06652
PTKc_Jak1_rpt2 - cd05079
PTKc_VEGFR3 - cd05102
PTKc_DDR2 - cd05095
STKc_myosinIII_like - cd06608
STKc_STK25-YSK1 - cd06642
PKc_MEK - cd06615
PKc_MKK3_6 - cd06617
STKc_MST3_like - cd06609
STKc_PRKX_like - cd05612
PKc_MKK5 - cd06619
PKc_MAPKK - cd06605
STKc_CDKL1_4 - cd07847
STKc_Nek6 - cd08228
SPS1 - COG0515
STKc_NDR1 - cd05628
PKc_MAPKK_plant_like - cd06623
PKc_MAPKK_PBS2_like - cd06622
PKc_MAPKK_Pek1_like - cd06621
STKc_MRCK_alpha - cd05623
STKc_phototropin_lik - cd05574
STKc_PKA - cd05580
PTKc_Srm_Brk - cd05148
STKc_LATS2 - cd05626
PTKc_Tie1 - cd05089
STKc_PDK1 - cd05581
STKc_ROCK_NDR_like - cd05573
STKc_LATS1 - cd05625
STKc_DMPK_like - cd05597
STKc_MAST - cd05609
STKc_CRIK - cd05601
STKc_LATS - cd05598
STKc_CDK2_3 - cd07860
STKc_CDKL2_3 - cd07846
STKc_TDY_MAPK_plant - cd07859
STKc_CDK1_euk - cd07861
STKc_CDK8_like - cd07842
STKc_CDK4 - cd07863
STKc_CDK7 - cd07841
STKc_MPK1 - cd07857
STKc_CDK5 - cd07839
STKc_Nek2 - cd08217
STKc_FA2-like - cd08529
STKc_CNK2-like - cd08530
STKc_CdkB_plant - cd07837
STKc_Nek1 - cd08218
STKc_Nek5 - cd08225
STKc_Nek3 - cd08219
STKc_Nek11 - cd08222
STKc_Nek4 - cd08223
STKc_Nek - cd08215
STKc_Cdc7_like - cd06627
STKc_MSK1_N - cd05613
STKc_MSK2_N - cd05614
STKc_cPKC_beta - cd05616
STKc_cPKC - cd05587
STKc_MSK_N - cd05583
STKc_Pho85 - cd07836
PTKc_RET - cd05045
PKc_STE - cd05122
STKc_GRK6 - cd05630
STKc_GRK4_like - cd05605
STKc_MEKK3 - cd06651
STKc_CCRK - cd07832
STKc_GRK4 - cd05631
STKc_MAPKKK_Byr2_lik - cd06628
STKc_MAPK - cd07834
STKc_MAPKKK - cd06606
STKc_cPKC_alpha - cd05615
STKc_GRK5 - cd05632
STKc_CDK4_6_like - cd07838
STKc_MAK_like - cd07830
STKc_CDK1_like - cd07835
STKc_CDK9_like - cd07840
Pkinase_Tyr - pfam07714
STKc_CDK_like - cd07829
Pkinase - pfam00069
TyrKc - smart00219
STYKc - smart00221
STKc_MST3 - cd06641
PTKc_Axl - cd05075
PTKc_Tyro3 - cd05074
PTKc_Axl_like - cd05035
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_Tyk2_rpt2 - cd05080
STKc_MST4 - cd06640
STKc_PKN - cd05589
STKc_CMGC - cd05118
STKc_Nek7 - cd08229
STKc_CDC2L6 - cd07867
PTKc_Csk_like - cd05039
PTKc_Src_like - cd05034
STKc_p70S6K - cd05584
STKc_RSK_N - cd05582
STKc_NLK - cd07853
STKc_MEKK4 - cd06626
STKc_nPKC_eta - cd05590
STKc_SGK2 - cd05603
STKc_nPKC_theta_delt - cd05592
STKc_aPKC - cd05588
STKc_Sty1_Hog1 - cd07856
STKc_SGK - cd05575
STKc_CDK10 - cd07845
STKc_SLK_like - cd06611
STKc_nPKC_theta - cd05619
STKc_MST1_2 - cd06612
PTK_Jak_rpt1 - cd05037
PTKc_Met_Ron - cd05058
PTKc_Ack_like - cd05040
PTKc_Fes_like - cd05041
STKc_PKC - cd05570
PTKc_Aatyk - cd05042
PTKc_Syk_like - cd05060
PTKc - cd00192
PTKc_Aatyk1_Aatyk3 - cd05087
PTKc_Zap-70 - cd05115
PTK_Jak2_Jak3_rpt1 - cd05078
PTKc_Aatyk2 - cd05086
PTKc_Syk - cd05116
PTKc_Fes - cd05084
STKc_Rim15_like - cd05611
STKc_GRK7 - cd05607
STKc_beta_ARK - cd05606
STKc_SGK1 - cd05602
STKc_GRK1 - cd05608
STKc_MEKK3_like - cd06625
STKc_MEKK1_plant - cd06632
STKc_YSK4 - cd06631
STKc_PKB_beta - cd05595
STKc_GRK3 - cd05633
STKc_Nek9 - cd08221
STKc_AGC - cd05123
STKc_PKB - cd05571
PTKc_Tie - cd05047
PTKc_Fer - cd05085
PKc - cd00180
PTKc_c-ros - cd05044
STKc_nPKC_epsilon - cd05591
STKc_cGK_PKG - cd05572
STKc_YPK1_like - cd05585
STKc_Sck1_like - cd05586
STKc_GRK - cd05577
STKc_PKB_alpha - cd05594
STKc_MAST_like - cd05579
STKc_PKB_gamma - cd05593
STKc_MOK - cd07831
STKc_Yank1 - cd05578
STKc_CDKL - cd07833
STKc_MAPKKK_Bck1_lik - cd06629
STKc_Nek8 - cd08220
S_TKc - smart00220
STKc_MEKK1 - cd06630
STKc_PCTAIRE2 - cd07872
STKc_PCTAIRE1 - cd07873
STKc_NAK1_like - cd06917
STKc_ERK5 - cd07855
STKc_Nek6_Nek7 - cd08224
STKc_CDC2L1 - cd07843
STKc_OSR1_SPAK - cd06610
STKc_MAPK15 - cd07852
Death_NMPP84 - cd08318
Death_TRAILR_DR4_DR5 - cd08315
DEATH - smart00005
Death_ank3 - cd08803
Death_ank - cd08317
Death_ank2 - cd08804
Death_FADD - cd08306
Death_PIDD - cd08779
Death_RIP1 - cd08777
Death_TRADD - cd08780
Death_RAIDD - cd08319
Death - pfam00531
Death_DRs - cd08784
Death - cd01670
Death_p75NR - cd08311
Death_TNFR1 - cd08313


Swiss-Prot Protein: Q13546
Identical to: NP_003795
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
PTKc_FGFR1cd050986.4e-081295
STKc_ROCKcd055960.000621332
STKc_TAO1cd066353.7e-051324
STKc_PAK6cd066590.000351311
STKc_p38gamma_MAPK12cd078800.000121361
PTKc_FGFR2cd051012e-082295
STKc_TAO2cd066343.1e-052325
PTKc_VEGFR2cd051032.2e-053292
STKc_PAKcd066141.3e-103304
STKc_CDK9cd078658.4e-063337
PTKc_DDRcd050511.1e-104283
PTKc_PDGFRcd050553.1e-074293
PTKc_Lyncd050725.6e-234288
STKc_ROCK2cd056210.000184332
STKc_TAOcd066072.1e-054317
PKc_MKK7cd066187.9e-104307
STKc_MAP4K3cd066453.7e-064288
STKc_p38cd078510.00024331
PTKc_FGFR4cd050993.9e-105311
STKc_p38alpha_MAPK14cd078770.000765361
PTKc_FGFR3cd051002e-076330
PTKc_EGFR_likecd050571.5e-097293
PTKc_InsRcd050614.3e-127297
PTKc_EphR_Bcd050652.7e-087289
PTKc_Tie2cd050883.7e-087325
STKc_STK10_LOKcd066445.7e-077308
PTKc_ALK_LTKcd050364.4e-128287
PTK_Jak1_rpt1cd050770.000198286
STKc_ASKcd066241.7e-078286
PTKc_Rorcd050488e-139288
PTKc_HER2cd051093.5e-089299
PTKc_HER4cd051103e-069312
PTKc_EGFRcd051082.9e-089329
STKc_MAP4K5cd066467.5e-059285
PTKc_InsR_likecd050329.8e-1410287
PTK_Rykcd050433e-1010293
PTKc_Ablcd050522.3e-2010289
PTKc_FAKcd050563.7e-1210293
PTKc_Tec_likecd050598e-1710286
PTKc_IGF-1Rcd050624.6e-1210287
PTKc_Lck_Blkcd050672.4e-2310288
PTKc_Frk_likecd050683.3e-2310288
PTKc_Cskcd050823e-2010288
PTKc_Ror1cd050909.7e-1110288
PTKc_Ror2cd050911e-0910288
PTKc_Btk_Bmxcd051134.4e-1710286
STKc_TEY_MAPK_plantcd078589.3e-0610367
PTK_CCK4cd050461.1e-0811287
PTKc_Trkcd050492.6e-1311287
PTKc_Muskcd050501.6e-1211287
PTKc_EphR_A2cd050631.2e-0711289
PTKc_EphR_A10cd050642.9e-0811289
PTKc_TrkAcd050925.9e-1011291
PTKc_TrkBcd050935.5e-1011291
PTKc_TrkCcd050943e-0811291
PTKc_DDR1cd050961.2e-0611287
PTKc_DDR_likecd050971.8e-0811287
STKc_TNIKcd066370.0005111289
PKc_MEK2cd066491.4e-0511337
PKc_MEK1cd066503.1e-0511341
STKc_CDK12cd078641.4e-0711290
PTKc_EphRcd050332.1e-1112289
PTKc_FGFRcd050538.8e-1112290
PTKc_EphR_Acd050663.1e-0712289
PTKc_Fyn_Yrkcd050706.6e-1312288
PTKc_Chkcd050839.7e-2812288
PTK_HER3cd051118e-0812293
PTKc_Itkcd051122.1e-2612286
PTKc_Tec_Rlkcd051142.1e-2312286
PKc_MKK4cd066161.2e-0612304
PKc_MAPKK_Byr1_likecd066201.8e-0912305
STKc_SLKcd066431.9e-0612306
PTKc_Jak_rpt2cd050384.8e-1413289
PTKc_Yescd050691.5e-1313288
PTKc_Srccd050715.9e-1313290
PTKc_Hckcd050731.7e-2013288
STKc_MAP4K3_likecd066134.1e-0913285
STKc_PFTAIRE2cd078700.0007913319
STKc_PCTAIRE3cd078710.0003413309
STKc_PCTAIRE_likecd078447.3e-0513309
PTKc_DDR2cd050951.6e-0814287
PTKc_Jak1_rpt2cd050793.9e-0914289
PTKc_VEGFR3cd051026.5e-0514292
STKc_myosinIII_likecd066084.2e-0614281
STKc_STK25-YSK1cd066420.000114305
STKc_MEKK2cd066521.6e-0514280
STKc_MEKK3_like_1cd066537.9e-0914290
STKc_ERK1_2_likecd078492.3e-0514314
STKc_MAPK4_6cd078540.0004114312
STKc_BUR1cd078662e-0514278
STKc_Nek10cd085284.9e-0514258
PTKc_Tie1cd050894.4e-0715314
PTKc_Srm_Brkcd051482.2e-1215288
STKc_ROCK_NDR_likecd055737.1e-0615331
STKc_phototropin_likcd055742.1e-0515254
STKc_PKAcd055802.1e-0615288
STKc_PDK1cd055817.5e-1215289
STKc_DMPK_likecd055970.0003715359
STKc_LATScd055984.4e-0615367
STKc_CRIKcd056019.5e-0615345
STKc_MASTcd056095.2e-0715341
STKc_MRCK_alphacd056230.0009415360
STKc_LATS1cd056250.000215378
STKc_LATS2cd056266.4e-0515367
STKc_NDR1cd056280.0004115360
STKc_PRKX_likecd056121.4e-0515344
PKc_MAPKKcd066052.1e-1115295
STKc_MST3_likecd066096.7e-0715301
PKc_MEKcd066153.2e-0815318
PKc_MKK3_6cd066174.4e-0915306
PKc_MKK5cd066190.0002815313
PKc_MAPKK_Pek1_likecd066217.2e-0715305
PKc_MAPKK_PBS2_likecd066224.2e-0715339
PKc_MAPKK_plant_likecd066237.6e-1215283
STKc_CDKL1_4cd078472.2e-0715323
STKc_Nek6cd082285.2e-0615290
SPS1COG05151.1e-3815469
PTKc_RETcd050453.5e-0816292
PKc_STEcd051223.6e-1416278
STKc_MSK_Ncd055832.9e-0616307
STKc_cPKCcd055871.3e-0616355
STKc_GRK4_likecd056052.9e-0816331
STKc_MSK1_Ncd056130.0003916307
STKc_MSK2_Ncd056140.0001316346
STKc_cPKC_betacd056162.5e-0516319
STKc_GRK6cd056303.8e-0516306
STKc_GRK4cd056311.3e-0516312
STKc_GRK5cd056325.2e-0616312
STKc_cPKC_alphacd056156.9e-0516312
STKc_MAPKKKcd066061.9e-2016278
STKc_Cdc7_likecd066272.4e-1316252
STKc_MAPKKK_Byr2_likcd066281.9e-1616289
STKc_MEKK3cd066514.1e-0916293
STKc_CCRKcd078321.1e-0716291
STKc_MAPKcd078344.6e-0616311
STKc_Pho85cd078361.9e-0516319
STKc_CdkB_plantcd078372.4e-0716291
STKc_CDK5cd078390.0004116290
STKc_CDK7cd078414.1e-0816286
STKc_CDK8_likecd078421.9e-0516278
STKc_MPK1cd078570.0001316326
STKc_TDY_MAPK_plantcd078592.3e-0616366
STKc_CDK2_3cd078600.0001416324
STKc_CDKL2_3cd078468.5e-0716285
STKc_CDK1_eukcd078619.4e-0516328
STKc_CDK4cd078630.0001716309
STKc_Nekcd082157.4e-1616281
STKc_Nek3cd082191.9e-0916287
STKc_Nek11cd082221.3e-0616290
STKc_Nek4cd082231.5e-0616289
STKc_Nek5cd082252.4e-0616289
STKc_Nek2cd082172.2e-0816290
STKc_Nek1cd082183.9e-0616289
STKc_FA2-likecd085291.3e-1316281
STKc_CNK2-likecd085302.3e-0516281
PTKc_Axl_likecd050351.5e-0717289
PTKc_Tyro3cd050748.1e-0817289
PTKc_Axlcd050752.1e-0517289
PTKc_Jak2_Jak3_rpt2cd050814e-1117289
PTKc_Tyk2_rpt2cd050803.4e-1117290
STKc_CMGCcd051187.3e-1117278
STKc_PKNcd055898.4e-0717337
STKc_MST4cd066407.2e-0517301
STKc_MST3cd066410.0001917305
STKc_CDK_likecd078295.8e-1117252
STKc_MAK_likecd078301.3e-0917278
STKc_CDK1_likecd078354.3e-0517309
STKc_CDK4_6_likecd078381.4e-0617278
STKc_CDK9_likecd078401.7e-0817278
PTKc_Csk_likecd050391.2e-1518288
STKc_CDC2L6cd078670.0001918342
STKc_Nek7cd082291.5e-0618290
PTKc_Src_likecd050341.5e-1419288
STKc_RSK_Ncd055821.3e-0620354
STKc_p70S6Kcd055849.5e-0620356
STKc_MEKK4cd066264.7e-1120279
STKc_NLKcd078530.0002220387
PTKccd001921.1e-3321286
PTKc_Ack_likecd050402.2e-1421287
PTKc_Fes_likecd050413.2e-1521287
PTKc_Aatykcd050428.4e-0921292
PTK_Jak_rpt1cd050372.9e-0621286
PTKc_Met_Roncd050585.7e-2121291
PTKc_Syk_likecd050605.1e-1321290
PTK_Jak2_Jak3_rpt1cd050782.3e-0521286
PTKc_Fescd050847.5e-1621287
PTKc_Aatyk2cd050865.4e-0621290
PTKc_Aatyk1_Aatyk3cd050871.8e-0621287
PTKc_Zap-70cd051151.4e-1521290
PTKc_Sykcd051161.1e-2121290
STKc_PKCcd055706.2e-0721337
STKc_SGKcd055750.0001521343
STKc_aPKCcd055880.0002321355
STKc_nPKC_theta_deltcd055921.4e-0721339
STKc_nPKC_etacd055903.9e-0521338
STKc_SGK2cd056035.7e-0521360
STKc_nPKC_thetacd056194.3e-0821340
STKc_SLK_likecd066113.1e-0721307
STKc_MST1_2cd066121.8e-0821278
STKc_CDK10cd078451.9e-0521279
STKc_Sty1_Hog1cd078560.0002921326
STKc_Rim15_likecd056110.0003822394
PKccd001802.6e-6123285
PTKc_c-roscd050445.9e-1223287
PTKc_Tiecd050478.8e-0723290
PTKc_Fercd050858.1e-1023287
STKc_AGCcd051232.9e-1323289
STKc_PKBcd055714e-0823382
STKc_cGK_PKGcd055722.1e-0623270
STKc_GRKcd055771.1e-0723300
STKc_MAST_likecd055793.4e-1223295
STKc_YPK1_likecd055851.6e-0523345
STKc_Sck1_likecd055864.5e-0523387
STKc_PKB_gammacd055931.4e-0523338
STKc_PKB_alphacd055945.6e-0623336
STKc_nPKC_epsiloncd055911.1e-0623338
STKc_PKB_betacd055953.3e-0523368
STKc_SGK1cd056020.0006623347
STKc_beta_ARKcd056061.9e-0523300
STKc_GRK7cd056077e-0523305
STKc_GRK1cd056081.4e-0823311
STKc_GRK3cd056330.0002823301
STKc_MEKK3_likecd066257.7e-1123290
STKc_YSK4cd066311.1e-0823290
STKc_MEKK1_plantcd066329.5e-1123281
STKc_Nek9cd082219.2e-0823287
STKc_Yank1cd055781.9e-1125289
STKc_MOKcd078317.1e-0725278
STKc_MAPKKK_Bck1_likcd066299.5e-1026279
STKc_CDKLcd078336.4e-0726278
STKc_Nek8cd082204.3e-0526287
STKc_MEKK1cd066309.3e-1027286
STKc_PCTAIRE2cd078729e-0527332
STKc_PCTAIRE1cd078730.0005427330
STKc_NAK1_likecd069171.2e-0533305
STKc_ERK5cd078550.0004735330
STKc_Nek6_Nek7cd082243.3e-0638290
STKc_CDC2L1cd078430.0002745263
STKc_OSR1_SPAKcd066101.9e-0946278
STKc_MAPK15cd078522.6e-0754318
Death_TRAILR_DR4_DR5cd083150.00068578667
Death_NMPP84cd083186.8e-05578666
Death_ankcd083173.3e-07581666
Death_ank3cd088030.00095581666
Death_ank2cd088043.4e-05581666
Death_FADDcd083061.4e-07583667
Death_RAIDDcd083191.6e-05583666
Death_RIP1cd087775.6e-70583668
Death_PIDDcd087795.1e-05583669
Death_TRADDcd087803.5e-08583668
Deathcd016707.5e-30586667
Death_DRscd087840.00013586666
Death_p75NRcd083110.00014593666
Death_TNFR1cd083130.00047596663
Pkinasepfam000693.5e-4917285
Deathpfam005316.7e-23584669
Pkinase_Tyrpfam077142e-3317285
TyrKcsmart002195.2e-3617285
STYKcsmart002217.4e-4917287
S_TKcsmart002202.9e-5527289
DEATHsmart000052.1e-28580668

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_041042Polymorphismp.ALA404SERN/A
Swiss-ProtVAR_041041Polymorphismp.ALA220VALN/A
Swiss-ProtVAR_058285Polymorphismp.ALA438VALN/A
Swiss-ProtVAR_041043Polymorphismp.ALA443VALN/A
Swiss-ProtVAR_041044Polymorphismp.ALA569VALN/A
Swiss-ProtVAR_041039Polymorphismp.ALA64VALN/A
Swiss-ProtVAR_021109Polymorphismp.GLU234LYSN/A
Swiss-ProtVAR_041040Polymorphismp.VAL81ILEN/A



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