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Results for the Protein: NP_001269
62241001

inhibitor of nuclear factor kappa-B kinase subunit alpha [Homo sapiens]
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Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

STKc_PAK6 - cd06659
STKc_JNK1 - cd07875
STKc_JNK2 - cd07876
PTKc_FGFR1 - cd05098
STKc_PAK5 - cd06658
STKc_PAK4 - cd06657
STKc_STK10_LOK - cd06644
STKc_PAK_I - cd06647
STKc_PAK2 - cd06655
STKc_JNK3 - cd07874
STKc_PAK - cd06614
STKc_PAK1 - cd06654
STKc_PAK3 - cd06656
STKc_p38alpha_MAPK14 - cd07877
STKc_TAO1 - cd06635
STKc_MAP4K4_6 - cd06636
STKc_CDK10 - cd07845
PTKc_Tie2 - cd05088
STKc_JNK - cd07850
STKc_myosinIIIB - cd06639
PKc_MKK7 - cd06618
PTKc_EphR_A2 - cd05063
PTKc_FGFR2 - cd05101
STKc_MAP4K5 - cd06646
STKc_SLK - cd06643
PTKc_EGFR_like - cd05057
STKc_TNIK - cd06637
STKc_MAP4K3 - cd06645
STKc_TAO2 - cd06634
STKc_TAO3 - cd06633
PTKc_TrkA - cd05092
STKc_CDK9 - cd07865
STKc_myosinIIIA - cd06638
STKc_myosinIII_like - cd06608
PTKc_DDR - cd05051
STKc_PFTAIRE2 - cd07870
STKc_PCTAIRE3 - cd07871
STKc_PCTAIRE1 - cd07873
STKc_PFTAIRE1 - cd07869
STKc_PCTAIRE2 - cd07872
STKc_MAPK4_6 - cd07854
STKc_BUR1 - cd07866
STKc_PCTAIRE_like - cd07844
PTKc_FGFR4 - cd05099
STKc_ERK5 - cd07855
PKc_MEK1 - cd06650
PKc_MEK2 - cd06649
STKc_TEY_MAPK_plant - cd07858
STKc_p38beta_MAPK11 - cd07878
STKc_p38delta_MAPK13 - cd07879
STKc_ASK - cd06624
STKc_p38gamma_MAPK12 - cd07880
PTKc_ALK_LTK - cd05036
STKc_MAP4K3_like - cd06613
PTKc_PDGFR - cd05055
PTKc_EphR_A - cd05066
PTKc_DDR_like - cd05097
PTKc_EphR_A10 - cd05064
PTKc_Ror2 - cd05091
STKc_Sty1_Hog1 - cd07856
STKc_ERK1_2_like - cd07849
STKc_MEKK3_like_1 - cd06653
STKc_MEKK2 - cd06652
STKc_CDKL - cd07833
STKc_CdkB_plant - cd07837
STKc_MST4 - cd06640
STKc_STK25-YSK1 - cd06642
PKc_MAPKK_Pek1_like - cd06621
STKc_MST3 - cd06641
STKc_CDKL1_4 - cd07847
STKc_Nek7 - cd08229
PKc_MEK - cd06615
SPS1 - COG0515
STKc_Nek6 - cd08228
STKc_Nek6_Nek7 - cd08224
STKc_CDK6 - cd07862
STKc_CDK12 - cd07864
STKc_CDKL5 - cd07848
STKc_NAK1_like - cd06917
STKc_ROCK_NDR_like - cd05573
STKc_DMPK_like - cd05597
STKc_LATS - cd05598
PTKc_Itk - cd05112
PTKc_Btk_Bmx - cd05113
STKc_OSR1_SPAK - cd06610
PTKc_Musk - cd05050
STKc_Sid2p_Dbf2p - cd05600
PTKc_Tec_Rlk - cd05114
STKc_PRKX_like - cd05612
STKc_MST3_like - cd06609
PKc_MAPKK - cd06605
STKc_MAST - cd05609
STKc_MRCK_alpha - cd05623
STKc_MRCK_beta - cd05624
STKc_NDR1 - cd05628
STKc_NLK - cd07853
STKc_CCRK - cd07832
STKc_TDY_MAPK_plant - cd07859
STKc_p38 - cd07851
STKc_CDK2_3 - cd07860
STKc_Pho85 - cd07836
STKc_CDK1_euk - cd07861
STKc_MAPK - cd07834
STKc_CDK5 - cd07839
STKc_CDK7 - cd07841
STKc_CDK8_like - cd07842
STKc_CNK2-like - cd08530
STKc_Nek4 - cd08223
STKc_Nek5 - cd08225
STKc_Nek10 - cd08528
STKc_FA2-like - cd08529
STKc_Nek8 - cd08220
STKc_Nek3 - cd08219
STKc_Nek - cd08215
STKc_Nek2 - cd08217
STKc_Nek1 - cd08218
STKc_CDK4 - cd07863
STKc_MPK1 - cd07857
STKc_MSK1_N - cd05613
STKc_cPKC - cd05587
STKc_MSK2_N - cd05614
STKc_cPKC_alpha - cd05615
STKc_GRK4_like - cd05605
STKc_MSK_N - cd05583
STKc_MEKK3 - cd06651
PTKc_Tec_like - cd05059
PKc_STE - cd05122
STKc_Yank1 - cd05578
STKc_cPKC_beta - cd05616
PTKc_DDR2 - cd05095
STKc_MEKK1 - cd06630
STKc_YSK4 - cd06631
STKc_PAK_II - cd06648
STKc_GRK6 - cd05630
STKc_MAPKKK_Byr2_lik - cd06628
STKc_MEKK1_plant - cd06632
STKc_GRK5 - cd05632
STKc_GRK4 - cd05631
STKc_MAPKKK - cd06606
STKc_Cdc7_like - cd06627
STKc_MEKK4 - cd06626
STKc_SLK_like - cd06611
STKc_CDK_like - cd07829
STKc_MAK_like - cd07830
STKc_CRIK - cd05601
STKc_MEKK3_like - cd06625
PTKc_Srm_Brk - cd05148
PTKc_Tie1 - cd05089
STKc_MOK - cd07831
STKc_CMGC - cd05118
STKc_PKN - cd05589
STYKc - smart00221
TyrKc - smart00219
Pkinase_Tyr - pfam07714
Pkinase - pfam00069
PTKc_Chk - cd05083
STKc_Nek11 - cd08222
STKc_CDK8 - cd07868
STKc_CDK4_6_like - cd07838
STKc_CDK9_like - cd07840
STKc_CDC2L6 - cd07867
STKc_CDK1_like - cd07835
PTKc_Fyn_Yrk - cd05070
PTKc_Abl - cd05052
PTKc_FGFR - cd05053
PTKc_InsR - cd05061
PTKc_Csk - cd05082
PTKc_Csk_like - cd05039
PTKc_Jak_rpt2 - cd05038
PTKc_InsR_like - cd05032
PTKc_Src_like - cd05034
PTKc_Axl_like - cd05035
PTKc_Lck_Blk - cd05067
PTKc_IGF-1R - cd05062
PTKc_Tyro3 - cd05074
PTKc_Frk_like - cd05068
PTKc_Jak1_rpt2 - cd05079
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_Hck - cd05073
PTKc_Axl - cd05075
PTKc_Yes - cd05069
PTKc_Src - cd05071
PTKc_Lyn - cd05072
PKc_MAPKK_PBS2_like - cd06622
STKc_CDKL2_3 - cd07846
PKc_MAPKK_plant_like - cd06623
STKc_CDC2L1 - cd07843
PKc_MAPKK_Byr1_like - cd06620
PK_STRAD - cd08216
STKc_PKA - cd05580
PKc_MKK3_6 - cd06617
PTKc_Ror - cd05048
PTKc_FAK - cd05056
PTKc_EphR - cd05033
PTKc_EphR_B - cd05065
PTKc_RET - cd05045
STKc_PDK1 - cd05581
STKc_MST1_2 - cd06612
STKc_TAO - cd06607
PTKc_Tyk2_rpt2 - cd05080
PTKc_Trk - cd05049
STKc_Nek9 - cd08221
PTKc_TrkB - cd05093
PTKc_TrkC - cd05094
STKc_MAPKKK_Bck1_lik - cd06629
COG3642 - COG3642
PKc_MKK4 - cd06616
STKc_RSK_N - cd05582
STKc_p70S6K - cd05584
STKc_PKB_alpha - cd05594
STKc_PKB_beta - cd05595
STKc_nPKC_theta_delt - cd05592
STKc_SGK1 - cd05602
STKc_PKB_gamma - cd05593
STKc_aPKC_zeta - cd05617
STKc_nPKC_theta - cd05619
STKc_nPKC_delta - cd05620
STKc_aPKC_iota - cd05618
STKc_SGK3 - cd05604
STKc_SGK2 - cd05603
STKc_nPKC_epsilon - cd05591
PTKc_Fes_like - cd05041
PTKc - cd00192
PTKc_Ack_like - cd05040
PTKc_Aatyk - cd05042
STKc_nPKC_eta - cd05590
PTKc_Tie - cd05047
PTKc_c-ros - cd05044
PTKc_Syk_like - cd05060
PTKc_Met_Ron - cd05058
STKc_PKB - cd05571
STKc_phototropin_lik - cd05574
STKc_SGK - cd05575
STKc_aPKC - cd05588
PTKc_Fes - cd05084
STKc_PKC - cd05570
PTKc_Syk - cd05116
PTKc_Fer - cd05085
PTKc_Zap-70 - cd05115
STKc_GRK7 - cd05607
STKc_GRK1 - cd05608
STKc_GRK3 - cd05633
STKc_GRK - cd05577
STKc_cGK_PKG - cd05572
STKc_AGC - cd05123
PKc - cd00180
STKc_beta_ARK - cd05606
STKc_MAST_like - cd05579
STKc_Sck1_like - cd05586
STKc_YPK1_like - cd05585
STKc_NDR_like - cd05599
S_TKc - smart00220
PTK_Ryk - cd05043
IKKbetaNEMObind - pfam12179


RefSeq Protein: NP_001269
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
PTKc_FGFR1cd050980.000191283
STKc_STK10_LOKcd066441.5e-071275
STKc_PAK_Icd066471.2e-061287
STKc_PAK2cd066555.6e-071290
STKc_PAK4cd066572.6e-051322
STKc_PAK5cd066582.2e-061308
STKc_PAK6cd066596.7e-091315
STKc_JNK1cd078750.00031363
STKc_JNK2cd078769.7e-061361
STKc_PAK1cd066546.9e-072289
STKc_PAK3cd066567e-072277
STKc_PAKcd066142.4e-132268
STKc_JNK3cd078742.6e-062361
STKc_TAO1cd066357.1e-054329
STKc_p38alpha_MAPK14cd078771.2e-074364
PTKc_Tie2cd050882.5e-055306
STKc_MAP4K4_6cd066360.000115270
STKc_CDK10cd078457.7e-095298
PTKc_EphR_A2cd050630.000146308
PTKc_FGFR2cd051010.000676283
PKc_MKK7cd066182.3e-056282
STKc_myosinIIIBcd066396.1e-066274
STKc_JNKcd078501.6e-066345
PTKc_EGFR_likecd050575.4e-057305
STKc_TNIKcd066372e-067270
STKc_SLKcd066431.6e-087300
STKc_MAP4K5cd066466.6e-067280
PTKc_TrkAcd050921.7e-058310
STKc_TAO3cd066330.000678318
STKc_TAO2cd066342.5e-058319
STKc_MAP4K3cd066453.8e-068299
PTKc_DDRcd050510.000399278
STKc_myosinIII_likecd066083.9e-109231
STKc_myosinIIIAcd066381.1e-069277
STKc_CDK9cd078657.9e-079287
PTKc_FGFR4cd050990.0002110288
STKc_PCTAIRE_likecd078441.6e-0710300
STKc_MAPK4_6cd078545.4e-0710331
STKc_ERK5cd078553.4e-0510340
STKc_BUR1cd078661.5e-0710276
STKc_PFTAIRE1cd078690.0001910305
STKc_PFTAIRE2cd078701.8e-0510299
STKc_PCTAIRE3cd078715e-0710300
STKc_PCTAIRE2cd078721.2e-0610319
STKc_PCTAIRE1cd078734.1e-0510312
PTKc_ALK_LTKcd050363.6e-1111263
PTKc_PDGFRcd050550.0006611272
PTKc_EphR_Acd050668.1e-0511295
PTKc_Ror2cd050910.0001811301
PTKc_EphR_A10cd050644e-0611252
PTKc_DDR_likecd050970.0001611282
STKc_MAP4K3_likecd066131.2e-1111299
STKc_ASKcd066246.4e-1311276
PKc_MEK2cd066490.000811333
PKc_MEK1cd066500.0009711358
STKc_TEY_MAPK_plantcd078583.2e-0711345
STKc_p38beta_MAPK11cd078785.6e-0611364
STKc_p38delta_MAPK13cd078790.000411328
STKc_p38gamma_MAPK12cd078804.2e-0811359
STKc_MEKK2cd066520.0003512278
STKc_MEKK3_like_1cd066532.6e-0512303
STKc_ERK1_2_likecd078491.3e-0612331
STKc_Sty1_Hog1cd078561.1e-0612321
PTKc_Muskcd050502.3e-0613299
PTKc_Btk_Bmxcd051133.8e-0613269
PTKc_Tec_Rlkcd051143.9e-0613273
PTKc_Itkcd051123.5e-0613268
STKc_ROCK_NDR_likecd055731e-1013340
STKc_DMPK_likecd055970.0001613363
STKc_LATScd055980.000213368
STKc_Sid2p_Dbf2pcd056002.7e-0813330
STKc_PRKX_likecd056127.2e-0913305
STKc_MRCK_betacd056240.0001713363
STKc_MRCK_alphacd056230.0008213361
STKc_NDR1cd056280.0002213342
STKc_MASTcd056095.2e-0613328
PKc_MAPKKcd066052.3e-0913247
STKc_MST3_likecd066097.2e-1013276
STKc_OSR1_SPAKcd066104.7e-1113281
PKc_MEKcd066153.5e-0813320
PKc_MAPKK_Pek1_likecd066211.6e-0813280
STKc_MST3cd066411.1e-0513289
STKc_STK25-YSK1cd066421.7e-0613276
STKc_MST4cd066402.4e-0513276
STKc_NAK1_likecd069172.8e-0813311
STKc_CDKLcd078335.9e-0713306
STKc_CdkB_plantcd078374.3e-0813302
STKc_CDKL1_4cd078471.5e-0813299
STKc_CDKL5cd078480.0001713300
STKc_CDK6cd078620.0002413300
STKc_CDK12cd078647.3e-0913300
STKc_Nek6_Nek7cd082247.4e-0913281
STKc_Nek6cd082282.8e-0613278
STKc_Nek7cd082291.2e-0713274
SPS1COG05152.3e-4513474
PTKc_Tec_likecd050591.7e-0814249
PTKc_DDR2cd050954.4e-0614297
PKc_STEcd051221.1e-1614299
STKc_Yank1cd055789.6e-1514300
STKc_MSK_Ncd055834.5e-0614318
STKc_GRK4_likecd056055.5e-1414331
STKc_MSK1_Ncd056134.3e-0514297
STKc_cPKCcd055876e-0714348
STKc_MSK2_Ncd056147.4e-0614381
STKc_cPKC_alphacd056155.5e-0714348
STKc_cPKC_betacd056163e-0514317
STKc_GRK6cd056301e-0814332
STKc_GRK4cd056312.2e-0814332
STKc_GRK5cd056328.5e-1014332
STKc_MAPKKKcd066064.9e-1914276
STKc_MEKK4cd066268e-1214276
STKc_Cdc7_likecd066271.1e-1214287
STKc_MAPKKK_Byr2_likcd066281e-1014273
STKc_MEKK1cd066301.1e-0714264
STKc_YSK4cd066316.2e-0914302
STKc_MEKK1_plantcd066321.2e-1014248
STKc_PAK_IIcd066481.3e-0914308
STKc_MEKK3cd066516.5e-0714261
STKc_CCRKcd078322.7e-1114301
STKc_MAPKcd078344.5e-0814344
STKc_Pho85cd078361.4e-1014300
STKc_CDK5cd078395.7e-0814301
STKc_CDK7cd078419.5e-1314311
STKc_CDK8_likecd078421e-0614287
STKc_p38cd078513.1e-0814284
STKc_NLKcd078538.8e-0714372
STKc_MPK1cd078571.9e-0714345
STKc_TDY_MAPK_plantcd078592.9e-0514346
STKc_CDK2_3cd078601.3e-0614300
STKc_CDK1_eukcd078615.8e-0714300
STKc_CDK4cd078631.2e-0714300
STKc_Nekcd082152.5e-2014300
STKc_Nek2cd082177.6e-1414300
STKc_Nek1cd082182.6e-1414273
STKc_Nek3cd082192.8e-1214270
STKc_Nek8cd082206.3e-0914300
STKc_Nek4cd082234.5e-1414276
STKc_Nek5cd082255.1e-2114273
STKc_CNK2-likecd085303.4e-1014300
STKc_Nek10cd085283.2e-0814260
STKc_FA2-likecd085295.1e-1114300
PTKc_InsR_likecd050321.3e-0615270
PTKc_Src_likecd050341e-0715249
PTKc_Axl_likecd050355.4e-0615276
PTKc_Jak_rpt2cd050383e-1015301
PTKc_Csk_likecd050393.8e-0815251
PTKc_Ablcd050522.7e-0615276
PTKc_FGFRcd050537.3e-0515253
PTKc_InsRcd050610.0002715281
PTKc_IGF-1Rcd050622.9e-0515266
PTKc_Lck_Blkcd050671.9e-0515306
PTKc_Frk_likecd050686.1e-0715275
PTKc_Yescd050693.3e-0715275
PTKc_Fyn_Yrkcd050704e-0615255
PTKc_Srccd050711.2e-0515281
PTKc_Lyncd050720.0001215271
PTKc_Hckcd050736.1e-0515279
PTKc_Tyro3cd050749.2e-0615280
PTKc_Axlcd050750.0003815276
PTKc_Jak1_rpt2cd050790.000415279
PTKc_Jak2_Jak3_rpt2cd050813.5e-0615301
PTKc_Cskcd050820.0001615279
PTKc_Chkcd050832.6e-0515300
PTKc_Tie1cd050891.4e-0515316
STKc_CMGCcd051184.4e-1415300
PTKc_Srm_Brkcd051482.2e-0815302
STKc_PKNcd055896.2e-0715361
STKc_CRIKcd056011.2e-0515307
STKc_SLK_likecd066116.5e-1115270
STKc_MEKK3_likecd066251.4e-0915278
STKc_CDK_likecd078293.6e-1315287
STKc_MAK_likecd078301.8e-1215299
STKc_MOKcd078311.9e-0815301
STKc_CDK1_likecd078353e-0815300
STKc_CDK4_6_likecd078382.3e-0915301
STKc_CDK9_likecd078401e-0815304
STKc_CDC2L6cd078677.8e-0515300
STKc_CDK8cd078680.0002515300
STKc_Nek11cd082223.4e-0715300
PTKc_RETcd050450.0001816252
PTKc_Rorcd050483.6e-0616279
PTKc_FAKcd050561.7e-0716307
PTKc_EphRcd050332.4e-0716242
PTKc_EphR_Bcd050651.4e-0516276
PTKc_Tyk2_rpt2cd050803.2e-0816281
STKc_PKAcd055804.5e-1416339
STKc_PDK1cd055812.6e-1316301
STKc_TAOcd066072.3e-0616318
STKc_MST1_2cd066123e-1316302
PKc_MKK3_6cd066173.1e-0516270
PKc_MAPKK_Byr1_likecd066202.3e-0616314
PKc_MAPKK_PBS2_likecd066221.6e-0516365
PKc_MAPKK_plant_likecd066231.4e-1416281
STKc_CDKL2_3cd078461.4e-0816301
STKc_CDC2L1cd078431.6e-0616287
PK_STRADcd082167.2e-0516309
PTKc_Trkcd050492e-0617297
PTKc_TrkBcd050930.0001117271
PTKc_TrkCcd050947.9e-0517329
STKc_MAPKKK_Bck1_likcd066298.8e-1017300
STKc_Nek9cd082212.9e-1117300
STKc_RSK_Ncd055822.1e-0618327
STKc_p70S6Kcd055842.5e-0618364
PKc_MKK4cd066160.0002418303
PTKccd001926.4e-0919298
PTKc_Fes_likecd050411.2e-1119250
PTKc_Aatykcd050420.0001419257
PTKc_c-roscd050442.8e-0619251
PTKc_Tiecd050470.0001119302
PTKc_Ack_likecd050402.6e-0619260
PTKc_Met_Roncd050581.3e-0519278
PTKc_Syk_likecd050608.3e-0719302
PTKc_Fescd050843.4e-0819274
PTKc_Fercd050854.1e-0819263
PTKc_Sykcd051161e-0519277
STKc_PKCcd055702.8e-0919304
STKc_PKBcd055713.9e-0919395
STKc_phototropin_likcd055742.3e-0919266
STKc_SGKcd055754.7e-0619353
STKc_aPKCcd055884.2e-0719380
STKc_nPKC_etacd055902.4e-0519349
STKc_nPKC_epsiloncd055918.7e-0719328
STKc_nPKC_theta_deltcd055922.1e-0719340
STKc_PKB_gammacd055934.1e-0619395
STKc_PKB_betacd055952.9e-0619358
STKc_PKB_alphacd055947.6e-0819356
STKc_SGK1cd056022.6e-0619365
STKc_SGK2cd056031.6e-0719330
STKc_SGK3cd056040.0001519330
STKc_aPKC_zetacd056172.1e-0619348
STKc_aPKC_iotacd056185.5e-0519317
STKc_nPKC_deltacd056200.0005919329
STKc_nPKC_thetacd056193.9e-0719343
PTKc_Zap-70cd051151.5e-0720277
PKccd001809.1e-7621307
STKc_AGCcd051235.1e-1721301
STKc_cGK_PKGcd055721.5e-1221284
STKc_GRKcd055773.9e-1221330
STKc_MAST_likecd055793.9e-1321282
STKc_YPK1_likecd055858.7e-0621362
STKc_Sck1_likecd055861.6e-0721416
STKc_beta_ARKcd056062.9e-0521295
STKc_GRK1cd056085.3e-1121330
STKc_GRK7cd056076.8e-1021331
STKc_GRK3cd056330.0002521326
STKc_NDR_likecd055996.7e-0622299
PTK_Rykcd050437.3e-0641234
Pkinasepfam000691.3e-3815304
COG3642COG36420.0007518212
Pkinase_Tyrpfam077144.8e-1415295
TyrKcsmart002191.8e-1415301
STYKcsmart002213.5e-6015299
S_TKcsmart002208.8e-6825301
IKKbetaNEMObindpfam121795e-19706743


Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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