Results for the protein: O00238

Results for the Protein: O00238

6226778

658

BMPR1B

NCBI, UniProt

BMR1B_HUMAN RecName: Full=Bone morphogenetic protein receptor type-1B; Short=BMP type-1B receptor; Short=BMPR-1B; AltName: CD_antigen=CDw293; Flags: Precursor

Known Diseases associated with this Protein:
BRACHYDACTYLY A2 (BDA2)
BRACHYDACTYLY, TYPE A2

6

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3

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8

Tips:

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Swiss-Prot Protein: O00238

Identical to: NP_001194

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_MAP4K4_6	cd06636	1.7e-05	187	492
PTKc_FGFR1	cd05098	0.00073	188	499
STKc_PAK_II	cd06648	0.0006	190	502
STKc_CDK9	cd07865	6.9e-08	190	484
PTKc_Ror1	cd05090	9.7e-05	191	494
PTKc_FGFR	cd05053	8.1e-05	192	496
PTKc_Tie2	cd05088	5.1e-05	192	496
PTKc_FGFR4	cd05099	0.001	192	502
STKc_myosinIIIA	cd06638	0.0002	192	491
STKc_p38	cd07851	0.00046	192	502
STKc_PAK	cd06614	1.9e-09	193	495
PTKc_FAK	cd05056	5.6e-07	194	499
STKc_ASK	cd06624	0.00013	194	491
PTKc_Trk	cd05049	2.6e-08	195	493
STKc_MAP4K3	cd06645	7.6e-05	195	492
STKc_MAP4K5	cd06646	8.9e-06	195	492
STKc_BUR1	cd07866	0.00016	195	489
PTKc_Abl	cd05052	3.3e-08	196	495
PTKc_EGFR_like	cd05057	6.7e-05	196	501
PTKc_TrkA	cd05092	3.4e-05	196	493
PTK_HER3	cd05111	0.00017	197	488
STKc_TNIK	cd06637	6.9e-06	197	493
STKc_CDK12	cd07864	9.7e-08	197	496
PTKc_ALK_LTK	cd05036	1.6e-08	198	493
PTKc_InsR	cd05061	3.1e-05	198	502
PTKc_IGF-1R	cd05062	3.8e-06	198	493
PTKc_EphR_A2	cd05063	0.00011	198	495
PTKc_Lck_Blk	cd05067	2.4e-10	198	494
PTKc_Frk_like	cd05068	3.1e-16	198	494
PTKc_Hck	cd05073	3.9e-08	198	494
PTKc_TrkB	cd05093	0.00019	198	502
PTKc_TrkC	cd05094	0.0006	198	502
PTKc_Ror2	cd05091	0.00038	198	494
PTKc_Ror	cd05048	4e-08	198	488
PTKc_EphR	cd05033	1.2e-08	199	495
PTKc_Jak_rpt2	cd05038	2.4e-09	199	491
PTKc_Yes	cd05069	1e-07	199	494
PTKc_Fyn_Yrk	cd05070	2.5e-07	199	494
PTKc_Lyn	cd05072	2.3e-08	199	494
PTKc_Itk	cd05112	1.4e-07	199	492
PTKc_Src	cd05071	6.6e-07	199	496
STKc_PCTAIRE_like	cd07844	0.00022	199	502
STKc_MAP4K3_like	cd06613	1.8e-08	200	489
STKc_ERK1_2_like	cd07849	0.00011	200	502
PTKc_Csk_like	cd05039	3.5e-10	201	494
PTKc_Tec_like	cd05059	7.2e-09	201	492
PTKc_EphR_A10	cd05064	0.00068	201	495
PTKc_EphR_B	cd05065	0.00015	201	495
PTKc_EphR_A	cd05066	0.00035	201	495
PTKc_Jak1_rpt2	cd05079	4e-05	201	495
PTKc_Jak2_Jak3_rpt2	cd05081	1.6e-07	201	495
PTKc_Csk	cd05082	7.4e-10	201	494
PTKc_DDR2	cd05095	6.4e-05	201	493
PTKc_Btk_Bmx	cd05113	5.4e-09	201	492
PTKc_Tec_Rlk	cd05114	3.9e-07	201	492
STKc_MST4	cd06640	0.00014	201	501
STKc_MST3	cd06641	2.2e-05	201	493
STKc_STK25-YSK1	cd06642	2.2e-05	201	501
STKc_Nek6_Nek7	cd08224	2e-06	201	496
STKc_Nek7	cd08229	6.3e-05	201	468
PTKc_Src_like	cd05034	8.7e-11	202	494
PTK_CCK4	cd05046	1.1e-05	202	493
PTKc_Musk	cd05050	2.7e-07	202	493
PTKc_Tyk2_rpt2	cd05080	6.7e-07	202	496
PTKc_Chk	cd05083	3.5e-07	202	494
PTKc_Tie1	cd05089	0.00012	202	501
STKc_PDK1	cd05581	1.1e-07	202	485
PKc_MAPKK	cd06605	2.4e-07	202	459
STKc_MST3_like	cd06609	4.2e-05	202	502
STKc_OSR1_SPAK	cd06610	5.1e-07	202	490
STKc_MST1_2	cd06612	4.9e-09	202	466
PKc_MEK	cd06615	8.4e-05	202	491
PKc_MKK3_6	cd06617	6.4e-05	202	496
PKc_MAPKK_Pek1_like	cd06621	1.5e-05	202	474
PKc_MAPKK_PBS2_like	cd06622	3.1e-05	202	494
PKc_MAPKK_plant_like	cd06623	1.4e-08	202	492
STKc_NAK1_like	cd06917	1.6e-06	202	501
STKc_CdkB_plant	cd07837	1.3e-07	202	493
STKc_CDK10	cd07845	1.9e-06	202	497
STKc_CDKL2_3	cd07846	0.00022	202	492
STKc_CDKL1_4	cd07847	2.6e-05	202	493
STKc_CDK6	cd07862	0.00095	202	493
PTKc_InsR_like	cd05032	1.4e-07	203	493
PTKc_PDGFR	cd05055	0.00021	203	495
STKc_Yank1	cd05578	8.1e-06	203	494
STKc_MSK_N	cd05583	0.00026	203	496
STKc_MSK1_N	cd05613	0.00077	203	496
STKc_MAPKKK	cd06606	2e-11	203	485
STKc_Cdc7_like	cd06627	9.9e-08	203	485
STKc_CCRK	cd07832	4.7e-08	203	455
STKc_Pho85	cd07836	0.00014	203	502
STKc_CDK5	cd07839	1.3e-05	203	492
STKc_CDK7	cd07841	5.1e-07	203	501
STKc_MPK1	cd07857	0.00017	203	500
STKc_CDK2_3	cd07860	0.00023	203	496
STKc_CDK1_euk	cd07861	5e-05	203	493
STKc_CDK4	cd07863	0.00019	203	493
STKc_CDK8_like	cd07842	0.00043	203	484
STKc_Nek	cd08215	2.9e-09	203	449
STKc_Nek1	cd08218	0.00034	203	468
STKc_Nek3	cd08219	2.2e-05	203	468
STKc_Nek8	cd08220	0.00012	203	462
STKc_Nek9	cd08221	0.00085	203	468
STKc_Nek5	cd08225	0.00087	203	468
STKc_Nek4	cd08223	0.00063	203	468
STKc_CNK2-like	cd08530	1.1e-05	203	496
PTKc_Axl_like	cd05035	1.2e-05	204	495
PTKc_Axl	cd05075	0.0001	204	495
PTKc_Tyro3	cd05074	0.00019	204	495
STKc_CDK1_like	cd07835	8.9e-06	204	493
STKc_CMGC	cd05118	8.4e-10	205	485
PKc_STE	cd05122	4e-11	205	484
PTKc_Srm_Brk	cd05148	2.9e-10	205	494
STKc_myosinIII_like	cd06608	1.3e-06	205	431
STKc_SLK_like	cd06611	4.1e-05	205	497
STKc_MEKK3_like	cd06625	1.3e-05	205	468
STKc_MEKK4	cd06626	1.5e-06	205	491
STKc_MEKK1_plant	cd06632	1.2e-05	205	487
STKc_CDK_like	cd07829	1.5e-07	205	486
STKc_MAK_like	cd07830	4.1e-06	205	485
STKc_MOK	cd07831	0.00042	205	487
STKc_MAPK	cd07834	7.7e-06	205	496
STKc_CDK4_6_like	cd07838	8.2e-05	205	487
STKc_CDK9_like	cd07840	3.5e-06	205	485
STKc_CDKL	cd07833	0.00065	206	485
STKc_FA2-like	cd08529	0.00039	207	437
PTKc	cd00192	4.9e-12	208	492
PTKc_Ack_like	cd05040	2.7e-07	208	493
PTKc_Fes_like	cd05041	3.5e-09	208	493
PTKc_c-ros	cd05044	3.1e-05	208	493
PTKc_Tie	cd05047	9.4e-05	208	496
PTKc_Aatyk	cd05042	0.0001	208	493
PTKc_Met_Ron	cd05058	0.00011	208	497
PTKc_Syk_like	cd05060	2.9e-06	208	496
PTKc_Fes	cd05084	3.2e-06	208	493
PTKc_Fer	cd05085	8.7e-06	208	493
PTKc_Syk	cd05116	5.4e-05	208	496
PTKc_Zap-70	cd05115	4.9e-05	209	496
PKc	cd00180	2.6e-52	210	491
STKc_AGC	cd05123	6.4e-07	210	489
STKc_cGK_PKG	cd05572	0.00035	210	498
STKc_GRK	cd05577	0.00017	210	455
STKc_MAST_like	cd05579	6.2e-05	210	484
STKc_beta_ARK	cd05606	0.00093	210	497
Activin_recp	pfam01064	6.1e-28	30	110
Pkinase	pfam00069	2.3e-67	204	491
TGF_beta_GS	pfam08515	6.9e-14	174	202
GS	smart00467	2.1e-13	174	204
Pkinase_Tyr	pfam07714	1e-17	204	491
TyrKc	smart00219	3.4e-14	204	491
STYKc	smart00221	5.4e-24	204	493
S_TKc	smart00220	1.6e-21	214	493

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041405	Polymorphism	p.ARG371GLN	N/A
Swiss-Prot	VAR_037967	Disease	p.ARG486GLN	Brachydactyly A2 (BDA2)
Swiss-Prot	VAR_041403	Polymorphism	p.ARG224HIS	N/A
Swiss-Prot	VAR_041401	Polymorphism	p.ARG31HIS	N/A
Swiss-Prot	VAR_041402	Polymorphism	p.ARG149TRP	N/A
Swiss-Prot	VAR_023820	Disease	p.ARG486TRP	Brachydactyly A2 (BDA2)
Swiss-Prot	VAR_041404	Polymorphism	p.ASP297ASN	N/A
Swiss-Prot	VAR_023819	Disease	p.ILE200LYS	Brachydactyly A2 (BDA2)
OMIM	603248.0004	Disease	p.ARG456GLN	BRACHYDACTYLY, TYPE A2
OMIM	603248.0002	Disease	p.ARG456TRP	BRACHYDACTYLY, TYPE A2
OMIM	603248.0001	Disease	p.ILE170LYS	BRACHYDACTYLY, TYPE A2

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258