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Results for the Protein: P11712
6686268

CP2C9_HUMAN RecName: Full=Cytochrome P450 2C9; AltName: Full=(R)-limonene 6-monooxygenase; AltName: Full=(S)-limonene 6-monooxygenase; AltName: Full=(S)-limonene 7-monooxygenase; AltName: Full=CYPIIC9; AltName: Full=Cytochrome P-450MP; AltName: Full=Cytochrome P450 MP-4; AltName: Full=Cytochrome P450 MP-8; AltName: Full=Cytochrome P450 PB-1; AltName: Full=S-mephenytoin 4-hydroxylase

Known Diseases associated with this Protein:
  GLIPIZIDE POOR M
  PHENYTOIN POOR METABOLIZER, INCLUDED;;
  TOLBUTAMIDE POOR METABOLIZER
  WARFARIN SENSITIVITY
  WARFARIN SENSITIVITY, INCLUDED;;
3
13
3
5
8
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Default View:

p450 - pfam00067
CypX - COG2124


Swiss-Prot Protein: P11712
Identical to: NP_000762
   Default View:




Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
p450pfam000674.5e-22930487
CypXCOG21242e-1831485

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
dbSNPrs1799853 Polymorphismp.ARG144CYSN/A
dbSNPrs7900194 Polymorphismp.ARG150HISN/A
dbSNPrs28371685 Polymorphismp.ARG335TRPN/A
Swiss-ProtVAR_013516Polymorphismp.ASP360GLUN/A
Swiss-ProtVAR_018865Polymorphismp.GLU272GLYN/A
Swiss-ProtVAR_008346Polymorphismp.GLY417ASPN/A
dbSNPrs2256871 Polymorphismp.HIS251ARGN/A
dbSNPrs1057910 Polymorphismp.ILE359LEUN/A
Swiss-ProtVAR_013515Polymorphismp.ILE359THRN/A
Swiss-ProtVAR_018862Polymorphismp.LEU19ILEN/A
Swiss-ProtVAR_024717Polymorphismp.LEU413PRON/A
Swiss-ProtVAR_018867Polymorphismp.PRO489SERN/A
Swiss-ProtVAR_008344Polymorphismp.TYR358CYSN/A
OMIM601130.0002 Diseasep.ARG144CYSWARFARIN SENSITIVITY
OMIM601130.0001 Diseasep.ILE359LEUTOLBUTAMIDE POOR METABOLIZER||WARFARIN SENSITIVITY, INCLUDED;;||PHENYTOIN POOR METABOLIZER, INCLUDED;;||GLIPIZIDE POOR M
OMIM601130.0003 Diseasep.LEU208VALWARFARIN SENSITIVITY



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