Home News About DMDM Database Statistics Research Publications Contact  

Results for the Protein: Q9UNQ0
67462103

ABCG2_HUMAN RecName: Full=ATP-binding cassette sub-family G member 2; AltName: Full=Breast cancer resistance protein; AltName: Full=CDw338; AltName: Full=Mitoxantrone resistance-associated protein; AltName: Full=Placenta-specific ATP-binding cassette transporter; AltName: Full=Urate exporter; AltName: CD_antigen=CD338

Known Diseases associated with this Protein:
  JUNIOR BLOOD GROUP SYSTEM, JR(A-) PHENOTYPE
  JUNIOR BLOOD GROUP SYSTEM, JR(A-) PHENOTYPE, INCLUDED
  URIC ACID CONCENTRATION, SERUM, QUANTITATIVE TRAIT LOCUS 1
5
18
5
2
16
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

ModF - COG1119
Ttg2A - COG1127
COG4181 - COG4181
COG1123 - COG1123
ZnuC - COG1121
AppF - COG4608
CcmA - COG1131
TagH - COG1134
MalK - COG3839
DppF - COG1124
COG4586 - COG4586
ABCG_PDR_domain1 - cd03233
ABCG_EPDR - cd03213
ABCG_PDR_domain2 - cd03232
ABCG_White - cd03234
sufC - COG0396
TauB - COG1116
GlnQ - COG1126
ABCC_MRP_domain2 - cd03244
FepC - COG1120
PhnK - COG1101
AbcC - COG1135
ABC_NikE_OppD_transp - cd03257
DppD - COG0444
SalX - COG1136
ABC_Carb_Solutes_lik - cd03259
ABC_subfamily_A - cd03263
ABC_MalK_N - cd03301
ABC_MJ0796_LolCDE_Ft - cd03255
ABC_NrtD_SsuB_transp - cd03293
ABC_drug_resistance_ - cd03264
ABCC_MsbA - cd03251
ABC_Class3 - cd03229
ABCC_MRP_Like - cd03228
ABCF_EF-3 - cd03221
ABCC_ATM1_transporte - cd03253
ABC_DR_subfamily_A - cd03230
ABCC_Protease_Secret - cd03246
ABCC_Hemolysin - cd03252
ABCC_MRP_domain1 - cd03250
ABCC_cytochrome_bd - cd03247
ABC_KpsT_Wzt - cd03220
ABC_cobalt_CbiO_doma - cd03226
ABC_ATPase - cd00267
ABC_cobalt_CbiO_doma - cd03225
ABC_Iron-Siderophore - cd03214
CysA - COG1118
PhnL - COG4778
PotA - COG3842
HisP - COG4598
ArtP - COG4161
ABC_NatA_like - cd03267
CbiO - COG1122
NatA - COG4555
ABC_MetN_methionine_ - cd03258
ABC_MTABC3_MDL1_MDL2 - cd03249
TauB - COG4525
CcmA - COG4133
ABC_PotA_N - cd03300
ABC_PhnC_transporter - cd03256
ABC_CysA_sulfate_imp - cd03296
ABC_CcmA_heme_export - cd03231
YhbG - COG1137
COG3638 - COG3638
BtuD - COG4138
COG4619 - COG4619
COG4136 - COG4136
ABC_ModC_molybdenum_ - cd03297
PstB - COG1117
ABC_YhbG - cd03218
ABC_BcrA_bacitracin_ - cd03268
ABC_FtsE_transporter - cd03292
ABCC_bacteriocin_exp - cd03245
ABC_Carb_Monos_I - cd03216
FtsE - COG2884
ABC_putative_ATPase - cd03269
ABC_ThiQ_thiamine_tr - cd03298
ABC_ModC_like - cd03299
ThiQ - COG3840
COG4674 - COG4674
ABC_Metallic_Cations - cd03235
ABC_DrrA - cd03265
LivF - COG0410
CeuD - COG4604
COG4152 - COG4152
ABC_FeS_Assembly - cd03217
ABC_HisP_GlnQ - cd03262
ABC_Org_Solvent_Resi - cd03261
ABC_PstB_phosphate_t - cd03260
LivG - COG0411
ABCC_Glucan_exporter - cd03254
ABC_TM1139_LivF_bran - cd03224
ABC_Carb_Monos_II - cd03215
ModC - COG4148
ABC_Mj1267_LivG_bran - cd03219
ABC_NatA_sodium_expo - cd03266
AAA - smart00382
ABC_tran - pfam00005
ABC2_membrane - pfam01061


Swiss-Prot Protein: Q9UNQ0
Identical to: NP_004818
   Default View:




































































































Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
ModFCOG11195.7e-0918270
Ttg2ACOG11272.3e-0829291
COG1123COG11235.2e-0632410
ZnuCCOG11212.5e-1033290
CcmACOG11311.7e-4533342
ABCG_EPDRcd032133.9e-12034268
ABCG_PDR_domain2cd032322.5e-7734268
ABCG_Whitecd032344.2e-7434268
ABCG_PDR_domain1cd032331.4e-4234268
sufCCOG03965.5e-0834289
TauBCOG11161e-0734305
DppFCOG11249.9e-0734280
TagHCOG11344.1e-0534288
ABCC_MRP_domain2cd032440.0008135270
FepCCOG11203.2e-1035309
GlnQCOG11260.0003635281
ABC_NikE_OppD_transpcd032579.1e-1136268
DppDCOG04448.5e-0636296
PhnKCOG11015.2e-0636268
AbcCCOG11352.4e-0536334
SalXCOG11364.1e-1336271
ABC_KpsT_Wztcd032201.7e-0737268
ABCF_EF-3cd032210.0001437263
ABCC_MRP_Likecd032287.1e-1337263
ABC_Class3cd032291.2e-1437263
ABC_DR_subfamily_Acd032301e-2137264
ABCC_Protease_Secretcd032461e-0837264
ABCC_cytochrome_bdcd032472.1e-1037268
ABCC_MRP_domain1cd032501.5e-0637263
ABCC_MsbAcd032510.0001837248
ABCC_Hemolysincd032521.3e-0637288
ABCC_ATM1_transportecd032534.1e-0837271
ABC_MJ0796_LolCDE_Ftcd032557.8e-1237264
ABC_Carb_Solutes_likcd032594.3e-1137268
ABC_subfamily_Acd032634.7e-1437275
ABC_drug_resistance_cd032643.7e-1437268
ABC_NrtD_SsuB_transpcd032934.3e-1237249
ABC_MalK_Ncd033016.3e-0837268
ABC_ATPasecd002675.1e-3438263
ABC_Iron-Siderophorecd032141.6e-1338268
ABC_cobalt_CbiO_domacd032252.2e-1638263
ABC_cobalt_CbiO_domacd032261.5e-0838265
CysACOG11184.7e-0539376
ABC_NatA_likecd032671.7e-0744268
ABC_MetN_methionine_cd032582e-0745270
CbiOCOG11221.3e-0945279
ABC_MTABC3_MDL1_MDL2cd032491.6e-0546289
ABC_PotA_Ncd033000.0003746244
ABC_CcmA_heme_exportcd032314.2e-0648260
ABC_PhnC_transportercd032561.7e-0948282
ABC_CysA_sulfate_impcd032962.1e-0648301
YhbGCOG11371.4e-0549279
ABC_ModC_molybdenum_cd032971.9e-0952268
ABC_YhbGcd032183.2e-0753275
PstBCOG11170.0005153278
ABCC_bacteriocin_expcd032451.3e-1057268
ABC_BcrA_bacitracin_cd032683.2e-1057268
ABC_FtsE_transportercd032927.8e-1157264
ABC_Carb_Monos_Icd032164.8e-0858267
ABC_Metallic_Cationscd032351.4e-1059268
ABC_DrrAcd032658.7e-1359274
ABC_putative_ATPasecd032695.1e-0659268
ABC_ThiQ_thiamine_trcd032982.5e-0759268
ABC_ModC_likecd032992.7e-0859274
LivFCOG04104.8e-0859282
ABC_FeS_Assemblycd032174.9e-0660282
ABC_TM1139_LivF_brancd032247.6e-0960276
ABCC_Glucan_exportercd032542.2e-0660281
ABC_PstB_phosphate_tcd032603.8e-0760273
ABC_HisP_GlnQcd032628.1e-0860264
ABC_Org_Solvent_Resicd032618.9e-1160284
LivGCOG04111.5e-0760276
ABC_Carb_Monos_IIcd032151.1e-0561264
ABC_Mj1267_LivG_brancd032192.8e-1264279
ABC_NatA_sodium_expocd032666e-1166268
COG4181COG41815.2e-0731268
AppFCOG46085.8e-0533335
MalKCOG38391.9e-0734376
COG4586COG45861.2e-0634340
PhnLCOG47783.7e-0540260
PotACOG38429.9e-0541379
ArtPCOG41611.9e-0642283
HisPCOG45980.0004142292
NatACOG45552.8e-1245305
CcmACOG41332.7e-0846264
TauBCOG45252.8e-0746306
COG3638COG36384.8e-0950299
BtuDCOG41383.5e-0550308
COG4619COG46197.3e-0850275
COG4136COG41360.0002551273
FtsECOG28845.9e-0758272
ThiQCOG38401.9e-0559289
COG4674COG46744e-0559279
COG4152COG41520.0003360334
CeuDCOG46046.7e-0560278
ModCCOG41480.0002761365
ABC_tranpfam000052.3e-2187214
ABC2_membranepfam010619.5e-54375586
AAAsmart003821.3e-0572270

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_030358Polymorphismp.ALA528THRN/A
Swiss-ProtVAR_067364Polymorphismp.ARG160GLNN/A
Swiss-ProtVAR_035355Polymorphismp.ASN590TYRN/A
Swiss-ProtVAR_022709Polymorphismp.ASP620ASNN/A
Swiss-ProtVAR_030357Polymorphismp.ASP296HISN/A
Swiss-ProtVAR_022704Polymorphismp.GLN166GLUN/A
dbSNPrs2231142 Polymorphismp.GLN141LYSN/A
Swiss-ProtVAR_067365Polymorphismp.GLY354ARGN/A
Swiss-ProtVAR_022705Polymorphismp.ILE206LEUN/A
Swiss-ProtVAR_022708Polymorphismp.PHE571ILEN/A
Swiss-ProtVAR_018349Polymorphismp.PHE431LEUN/A
Swiss-ProtVAR_018350Polymorphismp.PHE489LEUN/A
Swiss-ProtVAR_022706Polymorphismp.PHE208SERN/A
Swiss-ProtVAR_067366Polymorphismp.SER441ASNN/A
Swiss-ProtVAR_067363Polymorphismp.SER13LEUN/A
Swiss-ProtVAR_022707Polymorphismp.SER248PRON/A
Swiss-ProtVAR_022443Polymorphismp.THR316PRON/A
dbSNPrs2231137 Polymorphismp.VAL12METN/A
OMIM603756.0004 Diseasep.ARG236TERJUNIOR BLOOD GROUP SYSTEM, JR(a-) PHENOTYPE
OMIM603756.0001 Diseasep.ARG246TERJUNIOR BLOOD GROUP SYSTEM, JR(a-) PHENOTYPE
OMIM603756.0007 Diseasep.GLN141LYSURIC ACID CONCENTRATION, SERUM, QUANTITATIVE TRAIT LOCUS 1||JUNIOR BLOOD GROUP SYSTEM, JR(a-) PHENOTYPE, INCLUDED
OMIM603756.0002 Diseasep.GLN126TERURIC ACID CONCENTRATION, SERUM, QUANTITATIVE TRAIT LOCUS 1||JUNIOR BLOOD GROUP SYSTEM, JR(a-) PHENOTYPE, INCLUDED
OMIM603756.0003 Diseasep.VAL12METURIC ACID CONCENTRATION, SERUM, QUANTITATIVE TRAIT LOCUS 1||JUNIOR BLOOD GROUP SYSTEM, JR(a-) PHENOTYPE, INCLUDED



   |   1000 Hilltop Circle, Baltimore, MD 21250   |   Department of Biological Sciences   |   Phone: 410-455-2258