Results for the protein: O00329

Results for the Protein: O00329

67477424

5293

PIK3CD

NCBI, UniProt

PK3CD_HUMAN RecName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Short=PI3-kinase subunit delta; Short=PI3K-delta; Short=PI3Kdelta; Short=PtdIns-3-kinase subunit delta; AltName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; Short=PtdIns-3-kinase subunit p110-delta; Short=p110delta

			0 1 0 1 0

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Swiss-Prot Protein: O00329

Identical to: NP_005017

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
C2_PI3K_class_I_gamm	cd08399	3.7e-09	312	483
C2A_PI3K_class_II	cd04012	3.2e-07	314	485
C2_PI3K_like	cd08380	2e-47	314	479
C2_PI3K_class_I_alph	cd08398	1.5e-33	314	483
C2_PI3K_class_I_beta	cd08693	1.6e-110	314	481
PI3Ka_III	cd00870	9.7e-14	504	657
PI3Ka	cd00864	1.7e-61	505	657
PI3Ka_II	cd00869	6.5e-15	505	665
PI3Ka_I	cd00872	2.6e-96	505	676
PI3Kc	cd00891	6.1e-229	679	1040
PI3Kc_IB_gamma	cd00894	1.6e-112	679	1040
PI3Kc_III	cd00896	2.4e-44	679	1027
PI3Kc_I	cd05165	8.3e-289	679	1040
PI3Kc_II	cd05166	1.4e-108	679	1040
PI3Kc_IA_beta	cd05173	3e-240	679	1041
PI3Kc_IA_delta	cd05174		679	1040
PI3Kc_C2_alpha	cd05176	3.6e-82	679	1040
PI3Kc_IA_alpha	cd05175	9e-125	679	1040
PI3Kc_C2_gamma	cd05177	6.6e-68	679	1040
PI3Kc_C2_beta	cd00895	4.9e-77	685	1040
PI4Kc_III	cd00893	3.3e-14	721	1039
PI4Kc_III_alpha	cd05167	2.1e-19	734	1039
PIKKc_DNA-PK	cd05172	6.4e-07	741	982
PI3Kc_like	cd00142	1.1e-109	742	984
PIKKc	cd05164	1.7e-10	742	983
PIKKc_SMG1	cd05170	6.2e-05	742	983
PIKKc_ATR	cd00892	2e-07	747	982
PI4Kc_III_beta	cd05168	3.7e-15	754	1032
PIKKc_ATM	cd05171	1.9e-09	760	980
PIKKc_TOR	cd05169	3.7e-07	773	983
PI3K_p85B	pfam02192	1.3e-45	31	108
PI3K_rbd	pfam00794	6.4e-48	175	281
PI3K_C2	pfam00792	1.6e-50	337	470
PI3Ka	pfam00613	9.7e-71	499	684
PI3_PI4_kinase	pfam00454	7.7e-99	773	991
PI3K_p85B	smart00143	9.6e-27	31	108
PI3K_rbd	smart00144	1.1e-16	175	281
PI3K_C2	smart00142	5.5e-33	309	409
PI3Ka	smart00145	1.7e-86	501	684
PI3Kc	smart00146	3.6e-112	775	998

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs28730668	Polymorphism	p.VAL296ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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