Results for the protein: P07858

Results for the Protein: P07858

68067549

1508

CTSB

NCBI, UniProt

CATB_HUMAN RecName: Full=Cathepsin B; AltName: Full=APP secretase; Short=APPS; AltName: Full=Cathepsin B1; Contains: RecName: Full=Cathepsin B light chain; Contains: RecName: Full=Cathepsin B heavy chain; Flags: Precursor

			0 5 0 3 2

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Default View: Propeptide_C1 - pfam08127 Peptidase_C1A_Cathep - cd02621 Pept_C1 - smart00645 Peptidase_C1A_Cathep - cd02698 Peptidase_C1 - pfam00112 Peptidase_C1A_Cathep - cd02620 Peptidase_C1A - cd02248 Peptidase_C1 - cd02619	Swiss-Prot Protein: P07858 Identical to: NP_680092, NP_680093, NP_680090, NP_001899, NP_680091 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Peptidase_C1A_Cathep	cd02698	9.6e-19	80	331
Peptidase_C1A	cd02248	2.1e-73	81	328
Peptidase_C1A_Cathep	cd02620	4.9e-178	81	328
Peptidase_C1	cd02619	5.2e-60	83	327
Peptidase_C1	pfam00112	1.3e-122	80	329
Propeptide_C1	pfam08127	1.2e-20	26	66
Pept_C1	smart00645	1.6e-100	80	329

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs12338	Polymorphism	p.LEU26VAL	N/A
Swiss-Prot	VAR_051512	Polymorphism	p.PRO91LEU	N/A
dbSNP	rs17573	Polymorphism	p.SER235ASN	N/A
dbSNP	rs1803250	Polymorphism	p.SER53CYS	N/A
Swiss-Prot	VAR_051511	Polymorphism	p.SER53GLY	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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