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Results for the Protein: Q08345
729008
780

DDR1_HUMAN RecName: Full=Epithelial discoidin domain-containing receptor 1; Short=Epithelial discoidin domain receptor 1; AltName: Full=CD167 antigen-like family member A; AltName: Full=Cell adhesion kinase; AltName: Full=Discoidin receptor tyrosine kinase; AltName: Full=HGK2; AltName: Full=Mammary carcinoma kinase 10; Short=MCK-10; AltName: Full=Protein-tyrosine kinase 3A; AltName: Full=Protein-tyrosine kinase RTK-6; AltName: Full=TRK E; AltName: Full=Tyrosine kinase DDR; AltName: Full=Tyrosine-protein kinase CAK; AltName: CD_antigen=CD167a; Flags: Precursor
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Tips:
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Default View:

FA58C - smart00231
FA58C - cd00057
F5_F8_type_C - pfam00754
PTKc_CSF-1R - cd05106
PTKc_PDGFR_alpha - cd05105
PTKc_Kit - cd05104
PTKc_PDGFR_beta - cd05107
PTKc_PDGFR - cd05055
PTKc_FGFR1 - cd05098
STKc_myosinIIIA - cd06638
STKc_PAK - cd06614
PKc_MKK7 - cd06618
PTKc_FGFR - cd05053
PTKc_FGFR2 - cd05101
PTKc_FGFR3 - cd05100
STKc_CDK9 - cd07865
PTK_HER3 - cd05111
PTKc_FGFR4 - cd05099
STKc_ASK - cd06624
PTKc_HER4 - cd05110
STKc_PAK_II - cd06648
PTKc_VEGFR - cd05054
PTKc_HER2 - cd05109
PTKc_VEGFR3 - cd05102
PTKc_EGFR_like - cd05057
PTKc_VEGFR2 - cd05103
PTKc_Hck - cd05073
PTKc_Lyn - cd05072
PTKc_Csk - cd05082
PTKc_Src - cd05071
STKc_BUR1 - cd07866
PTKc_Fyn_Yrk - cd05070
STKc_SLK_like - cd06611
STKc_PDK1 - cd05581
PTK_Ryk - cd05043
PTKc_FAK - cd05056
PTKc_Yes - cd05069
PTKc_ALK_LTK - cd05036
PTKc_InsR - cd05061
PTKc_Abl - cd05052
PTKc_Frk_like - cd05068
PTKc_EphR_B - cd05065
PTKc_IGF-1R - cd05062
PTKc_Lck_Blk - cd05067
PTKc_TrkC - cd05094
PTKc_TrkB - cd05093
PTKc_DDR1 - cd05096
PKc_MAPKK_Byr1_like - cd06620
PTKc_TrkA - cd05092
PTKc_DDR_like - cd05097
PTKc_DDR2 - cd05095
PTKc_Musk - cd05050
PTKc_Trk - cd05049
PTK_CCK4 - cd05046
PTKc_Ror2 - cd05091
PTKc_DDR - cd05051
PTKc_InsR_like - cd05032
PTKc_EphR_A2 - cd05063
PTKc_Ror - cd05048
PTKc_Ror1 - cd05090
PTKc_EphR_A10 - cd05064
PTKc_Tie2 - cd05088
PTKc_Tec_Rlk - cd05114
STKc_CDK12 - cd07864
PTKc_Chk - cd05083
PTKc_Btk_Bmx - cd05113
PTKc_Jak1_rpt2 - cd05079
PTKc_Jak_rpt2 - cd05038
PTKc_EphR - cd05033
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_Tec_like - cd05059
PTKc_EphR_A - cd05066
PTKc_Tyk2_rpt2 - cd05080
STKc_MST3 - cd06641
STKc_MEKK3 - cd06651
STKc_MEKK3_like - cd06625
PTKc_Src_like - cd05034
PTKc_Csk_like - cd05039
STKc_MAP4K3_like - cd06613
PTKc_Srm_Brk - cd05148
STKc_myosinIII_like - cd06608
STKc_MST1_2 - cd06612
STKc_CDK10 - cd07845
STKc_MEKK3_like_1 - cd06653
STKc_MEKK2 - cd06652
STKc_Nek6_Nek7 - cd08224
STKc_CDKL - cd07833
STKc_NAK1_like - cd06917
STKc_CDKL1_4 - cd07847
PKc_MAPKK_plant_like - cd06623
STKc_Nek7 - cd08229
STKc_Nek6 - cd08228
PKc_MAPKK - cd06605
PKc_MAPKK_PBS2_like - cd06622
STKc_PKA - cd05580
STKc_MST3_like - cd06609
PTKc_Tie1 - cd05089
PKc_MKK5 - cd06619
PKc_MEK - cd06615
STKc_OSR1_SPAK - cd06610
STKc_Nek11 - cd08222
STKc_Nek - cd08215
STKc_Nek4 - cd08223
STKc_Nek10 - cd08528
STKc_CDK4 - cd07863
STKc_Nek3 - cd08219
STKc_CDK2_3 - cd07860
STKc_MAPKKK - cd06606
PKc_STE - cd05122
PTKc_RET - cd05045
STKc_Cdc7_like - cd06627
STKc_GRK4_like - cd05605
STKc_CDK7 - cd07841
STKc_MEKK1_plant - cd06632
STKc_MAPK - cd07834
STKc_CCRK - cd07832
STYKc - smart00221
STKc_CDK9_like - cd07840
TyrKc - smart00219
Pkinase_Tyr - pfam07714
STKc_MAK_like - cd07830
Pkinase - pfam00069
STKc_MAPKKK_Byr2_lik - cd06628
STKc_CDK1_like - cd07835
STKc_CDK_like - cd07829
PTKc_Axl - cd05075
PTKc_Tyro3 - cd05074
PTKc_Axl_like - cd05035
STKc_MOK - cd07831
PTKc_EGFR - cd05108
STKc_CNK2-like - cd08530
STKc_CDK8_like - cd07842
STKc_FA2-like - cd08529
STKc_MAPKKK_Bck1_lik - cd06629
STKc_Nek2 - cd08217
STKc_MEKK4 - cd06626
PKc_MAPKK_Pek1_like - cd06621
STKc_PKC - cd05570
STKc_CMGC - cd05118
STKc_YSK4 - cd06631
STKc_Nek8 - cd08220
PTKc_Syk - cd05116
STKc_CDKL2_3 - cd07846
STKc_CDK5 - cd07839
STKc_CdkB_plant - cd07837
PTKc_Fes_like - cd05041
PTK_Jak_rpt1 - cd05037
PTKc - cd00192
PTKc_Ack_like - cd05040
PTKc_Aatyk - cd05042
PTKc_c-ros - cd05044
PTKc_Aatyk1_Aatyk3 - cd05087
PTKc_Met_Ron - cd05058
PTKc_Syk_like - cd05060
PTKc_Fer - cd05085
PTKc_Aatyk2 - cd05086
PTKc_Fes - cd05084
PTK_Jak1_rpt1 - cd05077
PTK_Tyk2_rpt1 - cd05076
PTK_Jak2_Jak3_rpt1 - cd05078
PTKc_Tie - cd05047
STKc_MAST_like - cd05579
STKc_GRK - cd05577
STKc_cGK_PKG - cd05572
STKc_AGC - cd05123
PKc - cd00180
STKc_GRK1 - cd05608
STKc_Nek9 - cd08221
S_TKc - smart00220
PTKc_Itk - cd05112
PKc_MKK3_6 - cd06617
PTKc_Zap-70 - cd05115
STKc_Yank1 - cd05578
STKc_MEKK1 - cd06630


Swiss-Prot Protein: Q08345
Identical to: NP_054699
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
FA58Ccd000573.1e-6233184
PTKc_CSF-1Rcd051069.4e-27566910
PTKc_Kitcd051045.5e-14570909
PTKc_PDGFR_alphacd051051.6e-14570912
PTKc_PDGFR_betacd051073e-10570911
PTKc_PDGFRcd050553.5e-18575909
PTKc_FGFR1cd050984.4e-43582912
STKc_myosinIIIAcd066380.00024588905
STKc_PAKcd066141.7e-09589913
PKc_MKK7cd066180.00036594912
PTKc_FGFRcd050534.5e-52598906
PTKc_FGFR2cd051012.6e-40598912
PTKc_FGFR3cd051004.5e-29599908
PTKc_FGFR4cd050993.4e-43601913
PTK_HER3cd051118.6e-22601908
STKc_CDK9cd078650.00022601898
PTKc_VEGFRcd050545e-19602913
PTKc_EGFR_likecd050575e-44602913
PTKc_VEGFR3cd051021.1e-24602912
PTKc_VEGFR2cd051037.6e-19602913
PTKc_HER2cd051098.9e-25602908
PTKc_HER4cd051101.6e-11602908
STKc_ASKcd066242e-05602905
STKc_PAK_IIcd066487.7e-05602913
PTKc_ALK_LTKcd050363.6e-57603907
PTK_Rykcd050432.3e-23603910
PTKc_Ablcd050523.8e-63603909
PTKc_FAKcd050561.2e-61603913
PTKc_InsRcd050616.5e-53603913
PTKc_EphR_Bcd050656.5e-51603909
PTKc_Lck_Blkcd050678.7e-46603908
PTKc_IGF-1Rcd050622.6e-52603907
PTKc_Frk_likecd050687.6e-65603908
PTKc_Yescd050693.8e-40603909
PTKc_Fyn_Yrkcd050702.8e-46603909
PTKc_Srccd050711.5e-44603911
PTKc_Lyncd050721.8e-41603908
PTKc_Hckcd050733.6e-43603909
PTKc_Cskcd050823.1e-33603908
STKc_PDK1cd055811e-11603905
STKc_SLK_likecd066112.9e-05603912
STKc_BUR1cd078661.6e-05603911
PTKc_InsR_likecd050329.6e-73604907
PTK_CCK4cd050463.3e-65604907
PTKc_Trkcd050492.9e-98604907
PTKc_Muskcd050501.5e-92604907
PTKc_DDRcd050511.6e-232604907
PTKc_EphR_A2cd050635.7e-47604909
PTKc_EphR_A10cd050648.1e-40604909
PTKc_Rorcd050481.9e-87604905
PTKc_Ror1cd050901.3e-65604908
PTKc_Ror2cd050919e-57604908
PTKc_TrkAcd050921.8e-87604907
PTKc_TrkBcd050932.8e-82604911
PTKc_TrkCcd050949.6e-63604908
PTKc_DDR1cd050961.4e-244604907
PTKc_DDR2cd050953.9e-197604907
PTKc_DDR_likecd050972.2e-193604907
PKc_MAPKK_Byr1_likecd066205.4e-05604909
PTKc_EphRcd050338.9e-60605909
PTKc_Jak_rpt2cd050382.7e-56605909
PTKc_Tec_likecd050593.8e-45605906
PTKc_EphR_Acd050661.2e-53605911
PTKc_Jak1_rpt2cd050793.3e-38605910
PTKc_Tyk2_rpt2cd050809.3e-29605910
PTKc_Jak2_Jak3_rpt2cd050813.9e-40605909
PTKc_Chkcd050835.2e-38605908
PTKc_Tie2cd050884.6e-34605913
PTKc_Tec_Rlkcd051143.7e-50605906
PTKc_Btk_Bmxcd051132e-45605906
STKc_CDK12cd078645.6e-05605913
PTKc_Src_likecd050342.3e-58606909
PTKc_Csk_likecd050392.4e-21606908
PTKc_Srm_Brkcd051486.4e-41606908
STKc_myosinIII_likecd066083.6e-05606905
STKc_MST1_2cd066121.1e-05606905
STKc_MAP4K3_likecd066135e-07606904
STKc_MEKK3_likecd066256.6e-09606907
STKc_MST3cd066410.00049606913
STKc_MEKK3cd066514.2e-05606901
STKc_MEKK2cd066520.00012607908
STKc_MEKK3_like_1cd066530.00043607890
STKc_CDK10cd078453.6e-06607877
STKc_Nek6_Nek7cd082241.1e-05607911
PTKc_Tie1cd050895.2e-33608911
STKc_PKAcd055800.00053608907
PKc_MAPKKcd066054.7e-07608908
STKc_MST3_likecd066097.7e-05608873
STKc_OSR1_SPAKcd066102.2e-06608905
PKc_MEKcd066158.9e-06608913
PKc_MKK5cd066198.4e-05608910
PKc_MAPKK_PBS2_likecd066221.6e-05608913
PKc_MAPKK_plant_likecd066232e-08608911
STKc_NAK1_likecd069176e-05608911
STKc_CDKLcd078330.00014608905
STKc_CDKL1_4cd078478.8e-05608905
STKc_Nek6cd082287.6e-05608910
STKc_Nek7cd082290.00033608906
PTKc_RETcd050451.3e-37609912
PKc_STEcd051221.5e-11609904
STKc_GRK4_likecd056050.0001609909
STKc_MAPKKKcd066064.1e-17609905
STKc_Cdc7_likecd066278.4e-11609905
STKc_MEKK1_plantcd066324.8e-09609905
STKc_CCRKcd078321.3e-05609906
STKc_MAPKcd078343.5e-06609908
STKc_CDK7cd078412e-08609902
STKc_CDK2_3cd078600.00063609913
STKc_CDK4cd078630.00049609913
STKc_Nekcd082152.4e-13609910
STKc_Nek11cd082222.7e-06609905
STKc_Nek4cd082230.00075609905
STKc_Nek3cd082196.9e-05609910
STKc_Nek10cd085280.00048609907
PTKc_Axl_likecd050352.9e-56610909
PTKc_Tyro3cd050742.9e-50610909
PTKc_Axlcd050751.1e-50610910
PTKc_EGFRcd051083.8e-11610912
STKc_MAPKKK_Byr2_likcd066283.1e-07610905
STKc_CDK_likecd078292.2e-11610905
STKc_MOKcd078310.00023610905
STKc_CDK1_likecd078352.6e-05610913
STKc_MAK_likecd078302.5e-09610898
STKc_CDK9_likecd078402.7e-07610861
STKc_CDK8_likecd078425.3e-05611911
STKc_CNK2-likecd085300.0002611910
STKc_MAPKKK_Bck1_likcd066294.9e-07612905
STKc_FA2-likecd085293.7e-06612910
STKc_MEKK4cd066261e-08613905
STKc_Nek2cd082170.00015613905
PTKccd001921.6e-125614906
PTK_Jak_rpt1cd050371.9e-10614906
PTKc_Ack_likecd050406.3e-64614907
PTKc_Fes_likecd050415.2e-41614907
PTKc_Aatykcd050427.3e-19614907
PTKc_c-roscd050441.8e-63614907
PTKc_Tiecd050471.1e-42614906
PTKc_Met_Roncd050582e-55614911
PTKc_Syk_likecd050601.9e-53614910
PTK_Tyk2_rpt1cd050765e-06614906
PTK_Jak2_Jak3_rpt1cd050783.8e-09614906
PTK_Jak1_rpt1cd050773e-08614906
PTKc_Fescd050849.1e-50614907
PTKc_Fercd050851.1e-46614907
PTKc_Aatyk2cd050861.1e-27614907
PTKc_Aatyk1_Aatyk3cd050871.6e-34614907
PTKc_Sykcd051163.7e-37614910
STKc_CMGCcd051182e-09614905
STKc_PKCcd055700.00031614905
PKc_MAPKK_Pek1_likecd066211.9e-05614909
STKc_YSK4cd066311.7e-07614905
STKc_CdkB_plantcd078370.00017614899
STKc_CDK5cd078390.00061614905
STKc_CDKL2_3cd078467.5e-05614905
STKc_Nek8cd082203.8e-05614910
PKccd001807.3e-53616905
STKc_AGCcd051235.3e-08616905
STKc_cGK_PKGcd055722.7e-07616908
STKc_GRKcd055777.6e-05616901
STKc_MAST_likecd055791.1e-07616912
STKc_GRK1cd056080.00055616908
STKc_Nek9cd082211.1e-05616906
PTKc_Itkcd051121.6e-51624906
PKc_MKK3_6cd066177.2e-05633906
PTKc_Zap-70cd051151.1e-43634910
STKc_Yank1cd055780.00033639905
STKc_MEKK1cd066301.6e-06643906
F5_F8_type_Cpfam007541.5e-2846182
Pkinasepfam000693.5e-30610905
FA58Csmart002318e-5330185
Pkinase_Tyrpfam077142.2e-119610905
TyrKcsmart002195.2e-127610905
STYKcsmart002214.8e-43610889
S_TKcsmart002207.8e-37620905

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_041495Polymorphismp.ALA170ASPN/A
Swiss-ProtVAR_041494Polymorphismp.ARG169GLNN/A
Swiss-ProtVAR_041496Polymorphismp.ARG306TRPN/A
Swiss-ProtVAR_049716Polymorphismp.LEU833VALN/A
Swiss-ProtVAR_041497Polymorphismp.SER496ALAN/A
Swiss-ProtVAR_041492Polymorphismp.SER17GLYN/A
Swiss-ProtVAR_041493Polymorphismp.VAL100ALAN/A



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