Results for the protein: Q8IWW8

Results for the Protein: Q8IWW8

74714449

137872

ADHFE1

NCBI, UniProt

HOT_HUMAN RecName: Full=Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Short=HOT; AltName: Full=Alcohol dehydrogenase iron-containing protein 1; Short=ADHFe1; AltName: Full=Fe-containing alcohol dehydrogenase; Flags: Precursor

			0 2 0 1 1

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Swiss-Prot Protein: Q8IWW8

Identical to: NP_653251

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
LPO	cd08176	2.3e-26	47	461
PPD-like	cd08181	1.2e-13	47	435
Fe-ADH1	cd08185	4.1e-42	47	461
HVD	cd08193	2.5e-22	47	461
DHQ_Fe-ADH	cd07766	1.1e-24	51	459
HEPD	cd08182	6.8e-23	51	461
Fe-ADH2	cd08183	4.7e-16	51	461
MAR	cd08177	8.5e-09	51	461
Fe-ADH8	cd08186	1e-14	51	464
Fe-ADH3	cd08184	0.0002	51	396
HOT	cd08190		51	464
HHD	cd08191	3.7e-49	51	460
Fe-ADH6	cd08194	1.7e-30	51	461
Fe-ADH	cd08551	4.3e-161	51	460
AAD_C	cd08178	3.1e-18	52	461
Fe-ADH7	cd08192	8.9e-20	53	461
PDD	cd08180	1e-20	54	461
BDH	cd08187	2.5e-16	54	461
Fe-ADH4	cd08188	2.7e-25	54	461
COG1979	COG1979	4.9e-10	54	464
Fe-ADH5	cd08189	1e-21	57	460
NADPH_BDH	cd08179	1.5e-18	61	466
Fe-ADH	pfam00465	3.7e-135	51	456

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_039470	Polymorphism	p.ASP242VAL	N/A
dbSNP	rs1060242	Polymorphism	p.CYS449ARG	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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