Results for the protein: Q6P5Z2

Results for the Protein: Q6P5Z2

74749130

29941

PKN3

NCBI, UniProt

PKN3_HUMAN RecName: Full=Serine/threonine-protein kinase N3; AltName: Full=Protein kinase PKN-beta; AltName: Full=Protein-kinase C-related kinase 3

			0 3 0 1 2

Tips:

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Swiss-Prot Protein: Q6P5Z2

Identical to: NP_037487

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
HR1	cd00089	5.7e-29	97	170
HR1	cd00089	2.6e-17	171	243
C2_PKN-like	cd08687	2.3e-76	281	457
STKc_ROCK	cd05596	1.4e-33	518	883
STKc_ROCK2	cd05621	2.8e-26	518	883
STKc_PAK1	cd06654	4.1e-08	530	834
STKc_PAK2	cd06655	5.4e-08	531	842
STKc_PAK5	cd06658	1.6e-06	532	832
STKc_PAK_I	cd06647	1e-07	534	839
STKc_PAK4	cd06657	4.1e-06	535	824
STKc_PAK_II	cd06648	1.7e-11	536	831
STKc_ROCK1	cd05622	1.1e-26	537	884
STKc_TAO1	cd06635	4.9e-05	537	837
STKc_PAK3	cd06656	4.2e-08	538	843
STKc_PAK6	cd06659	1.4e-08	538	840
STKc_MAP4K4_6	cd06636	6.4e-05	540	818
PTKc_FGFR1	cd05098	2.7e-05	542	824
STKc_TAO	cd06607	1.1e-05	542	848
STKc_myosinIIIB	cd06639	5.7e-07	542	813
STKc_myosinIIIA	cd06638	5.5e-08	545	813
PTKc_FGFR4	cd05099	3.3e-06	546	838
PTKc_FGFR3	cd05100	8.5e-05	546	851
PTKc_FGFR2	cd05101	1.6e-05	546	824
STKc_PAK	cd06614	9.3e-16	546	831
STKc_CDK9	cd07865	5.5e-07	546	818
STKc_TAO2	cd06634	5.6e-05	547	854
PKc_MKK7	cd06618	1.6e-09	548	830
STKc_p38alpha_MAPK14	cd07877	0.00023	549	878
PTK_Ryk	cd05043	0.00073	550	793
STKc_ASK	cd06624	5.6e-14	550	818
STKc_TNIK	cd06637	7.6e-06	550	818
STKc_STK10_LOK	cd06644	8.8e-14	550	834
STKc_MAP4K3	cd06645	1.9e-06	550	817
STKc_MAP4K5	cd06646	7.6e-06	550	812
STKc_JNK	cd07850	6.7e-05	550	884
STKc_p38gamma_MAPK12	cd07880	2.2e-05	550	878
PTKc_EGFR_like	cd05057	8.9e-06	551	832
PTKc_ALK_LTK	cd05036	5.1e-08	551	792
STKc_p38beta_MAPK11	cd07878	9.7e-05	551	883
PTKc_InsR	cd05061	0.00036	552	823
PTKc_DDR_like	cd05097	0.00033	552	828
PTKc_VEGFR2	cd05103	0.00089	552	809
STKc_MST4	cd06640	2.4e-10	552	834
STKc_MST3	cd06641	4.3e-09	552	834
STKc_STK25-YSK1	cd06642	2.4e-09	552	834
PTKc_Src_like	cd05034	5.5e-08	554	809
PTK_CCK4	cd05046	7.1e-05	554	808
PTKc_Musk	cd05050	1.2e-05	554	813
PTKc_Yes	cd05069	2.1e-06	554	821
PTKc_Fyn_Yrk	cd05070	6.6e-05	554	809
PTKc_Src	cd05071	0.00011	554	811
PTKc_Lyn	cd05072	2.2e-06	554	809
PTKc_Hck	cd05073	6.6e-06	554	809
PTKc_Lck_Blk	cd05067	0.00018	554	825
PTKc_Tie2	cd05088	5.5e-07	554	833
PTKc_Srm_Brk	cd05148	2.7e-09	554	805
STKc_MAPK4_6	cd07854	8.5e-06	554	872
PTKc_InsR_like	cd05032	1.8e-07	555	808
PTKc_Trk	cd05049	4.8e-05	555	796
PTKc_Abl	cd05052	5.8e-07	555	813
PTKc_FGFR	cd05053	4.5e-06	555	795
PTKc_FAK	cd05056	0.00011	555	817
PTKc_EphR_A	cd05066	0.00069	555	819
PTKc_Frk_like	cd05068	1.8e-07	555	812
PTKc_EphR_A2	cd05063	0.0004	555	814
PTKc_Jak1_rpt2	cd05079	0.00013	555	827
PTKc_Csk	cd05082	0.00012	555	812
PTKc_Chk	cd05083	2.2e-05	555	815
PTKc_TrkA	cd05092	0.00031	555	815
PTKc_EGFR	cd05108	2.2e-05	555	861
PTKc_HER2	cd05109	0.00013	555	821
PTKc_HER4	cd05110	0.00029	555	856
PTK_HER3	cd05111	8.3e-05	555	822
PTKc_Itk	cd05112	4.9e-06	555	812
PTKc_Btk_Bmx	cd05113	1.8e-07	555	813
STKc_MAP4K3_like	cd06613	4.2e-13	555	817
PKc_MKK4	cd06616	7.4e-07	555	835
PKc_MAPKK_Byr1_like	cd06620	3.2e-08	555	849
PKc_MEK2	cd06649	9.7e-05	555	838
PKc_MEK1	cd06650	0.00021	555	842
STKc_PCTAIRE_like	cd07844	5.1e-08	555	836
STKc_CDK10	cd07845	1.4e-11	555	840
STKc_ERK5	cd07855	9.2e-06	555	871
STKc_CDK12	cd07864	2.1e-07	555	831
STKc_BUR1	cd07866	1.3e-09	555	818
STKc_PFTAIRE2	cd07870	3.1e-06	555	831
STKc_PCTAIRE3	cd07871	8.3e-07	555	831
STKc_PCTAIRE2	cd07872	6.3e-06	555	840
STKc_PCTAIRE1	cd07873	5.9e-06	555	835
STKc_PFTAIRE1	cd07869	4.3e-05	555	844
PTKc_EphR	cd05033	7.1e-06	556	794
PTKc_Csk_like	cd05039	1.2e-06	556	800
PTKc_Ror	cd05048	1.2e-05	556	805
PTKc_Tie1	cd05089	4.9e-06	556	836
PTKc_Ror1	cd05090	0.00077	556	814
STKc_myosinIII_like	cd06608	9.5e-09	556	818
STKc_Nek6_Nek7	cd08224	1.4e-09	556	814
STKc_Nek6	cd08228	8.2e-08	556	814
STKc_Nek7	cd08229	1.6e-09	556	814
PTKc_Jak_rpt2	cd05038	5.6e-08	557	831
PTKc_Tec_like	cd05059	1.3e-05	557	803
PTKc_Tec_Rlk	cd05114	1.5e-06	557	813
STKc_ROCK_NDR_like	cd05573	2.7e-53	557	882
STKc_PKA	cd05580	2.5e-93	557	851
STKc_PDK1	cd05581	3.2e-56	557	818
STKc_DMPK_like	cd05597	3.8e-44	557	887
STKc_CRIK	cd05601	2.4e-29	557	887
STKc_LATS	cd05598	5e-34	557	887
STKc_MAST	cd05609	1.5e-62	557	849
STKc_PRKX_like	cd05612	9.1e-75	557	852
STKc_MRCK_alpha	cd05623	6.9e-34	557	883
STKc_MRCK_beta	cd05624	1.5e-40	557	882
STKc_LATS2	cd05626	2e-24	557	887
STKc_NDR2	cd05627	1.2e-27	557	887
STKc_NDR1	cd05628	6.1e-26	557	887
STKc_NDR_like_fungal	cd05629	8e-39	557	887
STKc_phototropin_lik	cd05574	2.2e-56	557	844
STKc_NDR_like	cd05599	3.1e-24	557	887
STKc_Sid2p_Dbf2p	cd05600	9e-19	557	886
PKc_MAPKK	cd06605	1.4e-12	557	822
STKc_MST3_like	cd06609	2.4e-13	557	824
STKc_OSR1_SPAK	cd06610	1.6e-11	557	818
STKc_MST1_2	cd06612	9e-16	557	818
PKc_MEK	cd06615	8.6e-11	557	831
PKc_MKK3_6	cd06617	1.3e-07	557	833
PKc_MKK5	cd06619	6.2e-06	557	830
PKc_MAPKK_Pek1_like	cd06621	4.9e-08	557	822
PKc_MAPKK_PBS2_like	cd06622	2.8e-08	557	855
STKc_MEKK3_like	cd06625	2.3e-13	557	818
STKc_SLK	cd06643	7.6e-11	557	832
STKc_MEKK2	cd06652	1.9e-06	557	819
STKc_MEKK3_like_1	cd06653	6.4e-09	557	814
PKc_MAPKK_plant_like	cd06623	1.8e-18	557	811
STKc_NAK1_like	cd06917	9.1e-11	557	831
STKc_CDKL	cd07833	1.1e-08	557	818
STKc_CdkB_plant	cd07837	1.2e-10	557	819
STKc_CDC2L1	cd07843	4.4e-08	557	818
STKc_CDKL2_3	cd07846	6e-08	557	848
STKc_CDKL1_4	cd07847	9.9e-08	557	848
STKc_CDKL5	cd07848	2.9e-05	557	831
STKc_p38	cd07851	9.8e-08	557	837
STKc_ERK1_2_like	cd07849	1.9e-08	557	833
STKc_Sty1_Hog1	cd07856	1.6e-06	557	871
STKc_CDK6	cd07862	8.5e-06	557	844
STKc_TEY_MAPK_plant	cd07858	6.9e-06	557	878
SPS1	COG0515	7e-50	557	887
PTKc_RET	cd05045	2.8e-05	558	816
PTKc_EphR_B	cd05065	2.4e-05	558	819
PKc_STE	cd05122	8.7e-23	558	817
STKc_Yank1	cd05578	4e-53	558	818
STKc_MSK_N	cd05583	7e-82	558	837
STKc_cPKC	cd05587	7.3e-120	558	883
STKc_GRK4_like	cd05605	8.7e-62	558	839
STKc_MSK1_N	cd05613	4.5e-61	558	837
STKc_MSK2_N	cd05614	1.2e-74	558	884
STKc_cPKC_beta	cd05616	1.9e-106	558	883
STKc_cPKC_alpha	cd05615	6.6e-105	558	883
STKc_GRK6	cd05630	5.3e-51	558	839
STKc_GRK4	cd05631	3.2e-56	558	839
STKc_GRK5	cd05632	1.2e-52	558	839
STKc_MAPKKK	cd06606	3.5e-32	558	811
STKc_Cdc7_like	cd06627	8.5e-17	558	818
STKc_MAPKKK_Byr2_lik	cd06628	5.2e-21	558	818
STKc_MEKK3	cd06651	2.2e-10	558	820
STKc_CCRK	cd07832	3.3e-14	558	818
STKc_MAPK	cd07834	2.9e-09	558	838
STKc_Pho85	cd07836	1.8e-07	558	852
STKc_CDK5	cd07839	6.6e-06	558	818
STKc_CDK7	cd07841	5.2e-12	558	846
STKc_CDK8_like	cd07842	0.0001	558	818
STKc_NLK	cd07853	5.9e-05	558	879
STKc_MPK1	cd07857	1.4e-05	558	831
STKc_TDY_MAPK_plant	cd07859	1.1e-06	558	889
STKc_CDK2_3	cd07860	7.4e-07	558	836
STKc_CDK1_euk	cd07861	1.6e-06	558	848
STKc_CDK4	cd07863	5.1e-07	558	831
STKc_Nek	cd08215	4.8e-29	558	818
STKc_Nek1	cd08218	3.8e-18	558	813
STKc_Nek3	cd08219	5.1e-17	558	813
STKc_Nek8	cd08220	1.4e-09	558	813
STKc_Nek9	cd08221	4.7e-08	558	818
STKc_Nek11	cd08222	1.6e-22	558	818
STKc_Nek4	cd08223	6.2e-19	558	818
STKc_Nek5	cd08225	4.1e-16	558	818
STKc_Nek2	cd08217	3.8e-11	558	818
STKc_FA2-like	cd08529	1.5e-12	558	818
STKc_Nek10	cd08528	6e-07	558	814
STKc_CNK2-like	cd08530	1.8e-13	558	811
PTKc_Axl_like	cd05035	5.7e-06	559	802
PTKc_Tyro3	cd05074	1.5e-05	559	813
PTKc_Tyk2_rpt2	cd05080	4.8e-07	559	828
PTKc_Jak2_Jak3_rpt2	cd05081	3e-06	559	829
STKc_CMGC	cd05118	3.9e-14	559	818
STKc_PKN	cd05589	1.2e-231	559	882
STKc_LATS1	cd05625	2.4e-23	559	887
STKc_MAPKKK_Bck1_lik	cd06629	4.5e-12	559	818
STKc_MAK_like	cd07830	5.7e-10	559	818
STKc_CDK_like	cd07829	4.6e-15	559	818
STKc_CDK1_like	cd07835	4.6e-08	559	831
STKc_CDK4_6_like	cd07838	1.8e-09	559	818
STKc_CDK9_like	cd07840	3.3e-11	559	831
STKc_MOK	cd07831	5.1e-12	559	818
PK_STRAD_alpha	cd08227	0.0006	560	889
PK_STRAD	cd08216	0.00092	560	820
PTKc_Axl	cd05075	0.00059	562	813
STKc_RSK_N	cd05582	6.4e-84	562	882
STKc_p70S6K	cd05584	2.2e-87	562	884
STKc_Rim15_like	cd05611	9.8e-17	562	824
STKc_MEKK4	cd06626	7.5e-12	562	818
PTKc	cd00192	2.8e-11	563	813
PTKc_Ack_like	cd05040	1.2e-08	563	813
PTKc_Fes_like	cd05041	1.1e-09	563	814
PTKc_c-ros	cd05044	5.3e-05	563	796
PTKc_Tie	cd05047	1.4e-05	563	795
PTKc_Met_Ron	cd05058	1.9e-05	563	815
PTKc_Syk_like	cd05060	1.1e-06	563	795
PTKc_Fes	cd05084	2.9e-06	563	813
PTKc_Fer	cd05085	4.8e-08	563	813
PTKc_Aatyk1_Aatyk3	cd05087	0.00093	563	818
PTKc_Zap-70	cd05115	1.3e-05	563	823
PTKc_Syk	cd05116	3.9e-05	563	819
STKc_PKC	cd05570	4.6e-174	563	882
STKc_PKB	cd05571	5.2e-120	563	884
STKc_SGK	cd05575	3.3e-100	563	882
STKc_aPKC	cd05588	6e-98	563	883
STKc_nPKC_eta	cd05590	2.2e-112	563	883
STKc_nPKC_epsilon	cd05591	1.9e-113	563	883
STKc_nPKC_theta_delt	cd05592	6.9e-115	563	884
STKc_PKB_gamma	cd05593	8.9e-96	563	886
STKc_PKB_alpha	cd05594	1.5e-95	563	888
STKc_PKB_beta	cd05595	1.1e-103	563	884
STKc_SGK1	cd05602	6.6e-82	563	884
STKc_SGK3	cd05604	3.6e-84	563	889
STKc_SGK2	cd05603	2.3e-89	563	883
STKc_aPKC_zeta	cd05617	1.1e-85	563	883
STKc_aPKC_iota	cd05618	2.4e-81	563	883
STKc_nPKC_theta	cd05619	2.2e-103	563	884
STKc_nPKC_delta	cd05620	2.8e-100	563	884
STKc_MEKK1	cd06630	1.1e-10	563	819
STKc_YSK4	cd06631	4.4e-09	563	818
STKc_beta_ARK	cd05606	6.7e-46	564	838
STKc_GRK3	cd05633	2.3e-35	564	839
STKc_MEKK1_plant	cd06632	2.3e-15	564	818
PKc	cd00180	1.6e-65	565	816
PTKc_Aatyk	cd05042	2e-05	565	806
STKc_AGC	cd05123	1.4e-110	565	818
STKc_cGK_PKG	cd05572	2.4e-74	565	825
STKc_GRK	cd05577	6.6e-59	565	838
STKc_MAST_like	cd05579	1.1e-56	565	823
STKc_YPK1_like	cd05585	3.7e-79	565	881
STKc_Sck1_like	cd05586	1.2e-71	565	881
STKc_GRK7	cd05607	2.6e-43	565	838
STKc_GRK1	cd05608	1.3e-66	565	838
STKc_SLK_like	cd06611	1e-12	565	829
STKc_MAPK15	cd07852	1e-06	593	831
HR1	pfam02185	1.6e-16	19	76
HR1	pfam02185	6.4e-20	106	168
HR1	pfam02185	5.3e-16	179	241
Pkinase	pfam00069	7.1e-77	559	818
Pkinase_C	pfam00433	5.5e-09	838	885
Hr1	smart00742	1.1e-17	18	73
Hr1	smart00742	3e-20	105	165
Hr1	smart00742	8.4e-21	178	238
Pkinase_Tyr	pfam07714	4e-15	559	812
TyrKc	smart00219	4.4e-13	559	812
STYKc	smart00221	1.8e-79	559	818
S_TKc	smart00220	8.3e-95	569	818
KIND	smart00750	0.00071	649	826
S_TK_X	smart00133	1.4e-15	819	883

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_042346	Polymorphism	p.ALA180GLU	N/A
dbSNP	rs73669966	Polymorphism	p.GLY450SER	N/A
Swiss-Prot	VAR_050565	Polymorphism	p.VAL404LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258