Results for the protein: Q5D862

Results for the Protein: Q5D862

74755309

388698

FLG2

NCBI, UniProt

FILA2_HUMAN RecName: Full=Filaggrin-2; Short=FLG-2; AltName: Full=Intermediate filament-associated and psoriasis-susceptibility protein; Short=Ifapsoriasin

			0 15 0 5 10

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: S-100A1 - cd05025 S-100A6 - cd05029 S-100Z - cd05026 S-100A10_like - cd05031 S-100B - cd05027 calgranulins - cd05030 S-100A11 - cd05023 S-100 - cd00213 S-100A13 - cd05022 S-100A10 - cd05024 S_100 - pfam01023	Swiss-Prot Protein: Q5D862 Identical to: NP_001014364 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
S-100Z	cd05026	1.3e-19	1	92
S-100A6	cd05029	3.8e-07	1	89
S-100	cd00213	4.3e-44	2	89
S-100A13	cd05022	3e-10	2	94
S-100A11	cd05023	1.1e-09	2	89
S-100A10	cd05024	1.5e-10	2	95
calgranulins	cd05030	2.7e-18	2	89
S-100A10_like	cd05031	3.3e-23	2	95
S-100B	cd05027	7.7e-15	2	89
S_100	pfam01023	1.5e-12	4	47

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_042869	Polymorphism	p.ARG107GLN	N/A
Swiss-Prot	VAR_042871	Polymorphism	p.ARG276GLN	N/A
Swiss-Prot	VAR_042872	Polymorphism	p.CYS298SER	N/A
Swiss-Prot	VAR_042877	Polymorphism	p.GLN2239HIS	N/A
dbSNP	rs76514540	Polymorphism	p.GLN931HIS	N/A
Swiss-Prot	VAR_042876	Polymorphism	p.GLU1992ASP	N/A
Swiss-Prot	VAR_042873	Polymorphism	p.GLU723LYS	N/A
dbSNP	rs77345168	Polymorphism	p.GLY2055ARG	N/A
dbSNP	rs78399057	Polymorphism	p.GLY1140ASP	N/A
Swiss-Prot	VAR_042870	Polymorphism	p.GLY137GLU	N/A
Swiss-Prot	VAR_042875	Polymorphism	p.HIS1249ARG	N/A
dbSNP	rs61749580	Polymorphism	p.LEU168PHE	N/A
dbSNP	rs3818831	Polymorphism	p.LEU41PHE	N/A
Swiss-Prot	VAR_059173	Polymorphism	p.SER958TYR	N/A
Swiss-Prot	VAR_042874	Polymorphism	p.TYR881SER	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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