Results for the protein: Q8TD08

Results for the Protein: Q8TD08

74760462

225689

MAPK15

NCBI, UniProt

MK15_HUMAN RecName: Full=Mitogen-activated protein kinase 15; Short=MAP kinase 15; Short=MAPK 15; AltName: Full=Extracellular signal-regulated kinase 7; Short=ERK-7; AltName: Full=Extracellular signal-regulated kinase 8; Short=ERK-8

			0 4 0 3 1

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: Q8TD08

Identical to: NP_620590

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_TAO1	cd06635	7.2e-07	1	305
STKc_MAP4K4_6	cd06636	1.7e-06	1	273
STKc_myosinIIIA	cd06638	1.4e-06	1	304
STKc_TAO3	cd06633	5.3e-05	1	331
STKc_myosinIIIB	cd06639	4.9e-06	1	305
STKc_PAK_II	cd06648	1.1e-11	1	311
STKc_PAK1	cd06654	2e-08	1	327
STKc_PAK2	cd06655	4.5e-09	1	323
STKc_PAK3	cd06656	5.3e-09	1	325
STKc_PAK5	cd06658	1.7e-07	1	308
STKc_PAK6	cd06659	5.8e-09	1	327
STKc_PAK4	cd06657	3.4e-08	1	323
STKc_PAK_I	cd06647	2.6e-10	1	295
STKc_JNK	cd07850	5.2e-64	1	343
STKc_p38	cd07851	5.7e-92	1	348
STKc_CDK9	cd07865	6.5e-30	1	304
STKc_JNK3	cd07874	3.8e-48	1	345
STKc_JNK1	cd07875	3.6e-43	1	347
STKc_JNK2	cd07876	2.3e-50	1	345
STKc_Sty1_Hog1	cd07856	1.1e-78	1	342
PTK_Ryk	cd05043	0.00032	2	227
STKc_p38gamma_MAPK12	cd07880	8.3e-69	2	348
PTKc_FGFR	cd05053	4.3e-07	3	270
STKc_p38beta_MAPK11	cd07878	6.5e-72	3	348
STKc_p38delta_MAPK13	cd07879	9.6e-72	3	348
STKc_TNIK	cd06637	4.5e-08	4	273
STKc_BUR1	cd07866	2.4e-42	4	304
PTKc_EphR	cd05033	3.2e-07	5	269
PTKc_EphR_A2	cd05063	5e-05	5	269
PTKc_EphR_B	cd05065	4.6e-06	5	269
PTKc_EphR_A	cd05066	8.4e-05	5	269
PTKc_Ror2	cd05091	0.00094	5	264
PTKc_FGFR4	cd05099	3.1e-07	5	290
PTKc_FGFR3	cd05100	0.00013	5	309
PTKc_Itk	cd05112	7.6e-06	5	258
PTKc_Tec_Rlk	cd05114	9.2e-06	5	285
STKc_SLK_like	cd06611	6.7e-11	5	317
STKc_MAPK15	cd07852	1.7e-247	5	343
PTKc_FGFR1	cd05098	0.00018	6	292
PTKc_FGFR2	cd05101	8.9e-05	6	276
STKc_TAO	cd06607	3.5e-08	6	344
STKc_TAO2	cd06634	1.8e-07	6	306
STKc_MST3	cd06641	1.5e-08	6	308
STKc_STK25-YSK1	cd06642	3.3e-09	6	308
STKc_MST4	cd06640	1.3e-07	6	308
PTKc_ALK_LTK	cd05036	1.2e-05	7	259
PTKc_Musk	cd05050	4.4e-08	7	259
PTKc_EGFR_like	cd05057	0.00014	7	297
PTKc_Tie2	cd05088	0.00087	7	291
PTKc_Ror1	cd05090	0.00026	7	264
PTK_HER3	cd05111	4.8e-06	7	287
STKc_MEKK3_like	cd06625	5.6e-14	7	304
STKc_MEKK3	cd06651	2.1e-10	7	306
STKc_p38alpha_MAPK14	cd07877	4.5e-68	7	348
PTKc_Ror	cd05048	2.2e-07	8	268
PTKc_Abl	cd05052	2.6e-06	8	269
PTKc_FAK	cd05056	5.6e-07	8	292
PTKc_IGF-1R	cd05062	0.00089	8	262
PTKc_Lck_Blk	cd05067	0.00011	8	307
PTKc_Yes	cd05069	7.8e-06	8	273
PTKc_Frk_like	cd05068	6.7e-08	8	272
PTKc_Src	cd05071	3e-05	8	274
PTKc_Hck	cd05073	0.00011	8	291
PTKc_Fyn_Yrk	cd05070	6.9e-05	8	291
PTKc_Lyn	cd05072	0.00013	8	268
PTKc_TrkA	cd05092	4.5e-05	8	283
PTKc_TrkB	cd05093	2.2e-05	8	279
PTKc_TrkC	cd05094	6.2e-05	8	312
PTKc_EGFR	cd05108	2.7e-05	8	322
PTKc_HER2	cd05109	1.8e-05	8	297
PTKc_HER4	cd05110	2.6e-05	8	312
STKc_STK10_LOK	cd06644	3.2e-08	8	322
STKc_MAP4K3	cd06645	6.7e-06	8	273
STKc_MAP4K5	cd06646	8e-06	8	273
STKc_CDK10	cd07845	5.8e-50	8	313
STKc_ERK5	cd07855	2.6e-99	8	335
STKc_TEY_MAPK_plant	cd07858	1.4e-105	8	348
STKc_CDK12	cd07864	1.6e-46	8	304
PTKc_InsR_like	cd05032	3.6e-06	9	270
PTKc_Src_like	cd05034	2.3e-09	9	268
PTKc_Jak_rpt2	cd05038	1.4e-08	9	308
PTKc_Trk	cd05049	6.2e-10	9	283
PTKc_Jak1_rpt2	cd05079	2.3e-05	9	307
PTKc_Tyk2_rpt2	cd05080	5.8e-06	9	277
PTKc_Btk_Bmx	cd05113	2.8e-06	9	273
STKc_GRK6	cd05630	9.3e-07	9	307
STKc_GRK4	cd05631	2e-06	9	307
STKc_GRK5	cd05632	4.6e-07	9	307
STKc_MAP4K3_like	cd06613	1.4e-12	9	303
STKc_ASK	cd06624	4e-09	9	304
STKc_PCTAIRE_like	cd07844	8.7e-60	9	304
STKc_ERK1_2_like	cd07849	1.3e-112	9	345
STKc_MAPK4_6	cd07854	5.8e-61	9	334
STKc_PFTAIRE2	cd07870	8.9e-44	9	304
PTKc_Csk	cd05082	0.00057	10	288
PTKc_Chk	cd05083	0.00014	10	264
PKc_MAPKK_Byr1_like	cd06620	1.7e-10	10	315
STKc_PFTAIRE1	cd07869	2.5e-27	10	312
STKc_PCTAIRE3	cd07871	3.2e-45	10	304
STKc_PCTAIRE2	cd07872	8.3e-34	10	324
STKc_PCTAIRE1	cd07873	3.9e-40	10	312
PK_STRAD	cd08216	3.2e-06	10	322
STKc_Nek6_Nek7	cd08224	3.1e-11	10	263
STKc_Nek6	cd08228	4.5e-09	10	263
STKc_Nek7	cd08229	2.8e-10	10	295
PTKc_Jak2_Jak3_rpt2	cd05081	2.8e-06	11	306
STKc_ROCK_NDR_like	cd05573	4.8e-12	11	338
STKc_phototropin_lik	cd05574	4.2e-09	11	312
STKc_PKA	cd05580	1.5e-09	11	314
STKc_PDK1	cd05581	3.8e-15	11	304
STKc_DMPK_like	cd05597	1.1e-05	11	352
STKc_LATS	cd05598	6.7e-05	11	383
STKc_MAST	cd05609	3e-09	11	334
STKc_PRKX_like	cd05612	1e-06	11	322
STKc_MRCK_alpha	cd05623	4e-05	11	353
STKc_MRCK_beta	cd05624	3.5e-05	11	352
STKc_CRIK	cd05601	4.4e-07	11	309
STKc_MST3_like	cd06609	1.7e-13	11	321
STKc_OSR1_SPAK	cd06610	8.3e-11	11	287
PKc_MEK	cd06615	1.9e-11	11	319
PKc_MKK7	cd06618	2.9e-09	11	342
PKc_MKK5	cd06619	2.1e-05	11	323
PKc_MEK2	cd06649	1.3e-06	11	334
STKc_MEKK2	cd06652	1.5e-07	11	287
STKc_MEKK3_like_1	cd06653	2.3e-08	11	286
STKc_CDKL	cd07833	3.6e-65	11	304
STKc_CdkB_plant	cd07837	1.3e-63	11	305
STKc_CDKL2_3	cd07846	2.3e-50	11	304
STKc_CDKL1_4	cd07847	5.5e-66	11	304
STKc_CDKL5	cd07848	3.2e-45	11	304
STKc_CDK6	cd07862	1.4e-47	11	304
SPS1	COG0515	5.1e-67	11	490
PKc_STE	cd05122	9e-29	12	303
STKc_Yank1	cd05578	1.8e-14	12	304
STKc_MSK_N	cd05583	1.2e-08	12	322
STKc_cPKC	cd05587	2.1e-06	12	342
STKc_MSK1_N	cd05613	3.8e-05	12	322
STKc_MSK2_N	cd05614	1.1e-07	12	363
STKc_cPKC_alpha	cd05615	2.1e-05	12	344
STKc_cPKC_beta	cd05616	1.2e-05	12	332
STKc_GRK4_like	cd05605	2.6e-09	12	307
STKc_MAPKKK	cd06606	1.8e-30	12	304
STKc_myosinIII_like	cd06608	1.9e-11	12	230
PKc_MAPKK_plant_like	cd06623	6.7e-17	12	309
STKc_Cdc7_like	cd06627	1.8e-18	12	304
STKc_MAPKKK_Byr2_lik	cd06628	1.8e-18	12	304
STKc_CCRK	cd07832	3.8e-87	12	305
STKc_MAPK	cd07834	3.5e-183	12	342
STKc_Pho85	cd07836	4.4e-72	12	304
STKc_CDK5	cd07839	4.6e-62	12	304
STKc_CDK7	cd07841	2.8e-72	12	315
STKc_CDK8_like	cd07842	1.9e-29	12	304
STKc_NLK	cd07853	7.7e-70	12	370
STKc_MPK1	cd07857	2.4e-99	12	343
STKc_TDY_MAPK_plant	cd07859	9e-88	12	348
STKc_CDK2_3	cd07860	4.6e-68	12	304
STKc_CDK1_euk	cd07861	6.4e-71	12	304
STKc_CDK4	cd07863	3.5e-59	12	304
STKc_Nek	cd08215	1.1e-19	12	304
STKc_Nek2	cd08217	3.7e-15	12	304
STKc_Nek1	cd08218	1.4e-09	12	274
STKc_Nek3	cd08219	1.5e-11	12	286
STKc_Nek8	cd08220	2.9e-08	12	304
STKc_Nek9	cd08221	1.6e-09	12	304
STKc_Nek11	cd08222	1.1e-07	12	273
STKc_Nek4	cd08223	4.2e-12	12	304
STKc_Nek5	cd08225	3.6e-10	12	274
STKc_Nek10	cd08528	1.9e-09	12	272
STKc_FA2-like	cd08529	2.1e-09	12	273
STKc_CNK2-like	cd08530	2.7e-10	12	304
PTKc_Axl_like	cd05035	5.9e-05	13	269
PTKc_Tyro3	cd05074	2.5e-05	13	269
STKc_CMGC	cd05118	9.5e-121	13	304
PTKc_Srm_Brk	cd05148	3.9e-08	13	268
STKc_PKN	cd05589	3e-07	13	343
STKc_MST1_2	cd06612	8.3e-14	13	304
STKc_SLK	cd06643	2.6e-09	13	320
PKc_MEK1	cd06650	7e-07	13	341
STKc_NAK1_like	cd06917	1.6e-11	13	285
STKc_CDK_like	cd07829	7.5e-97	13	304
STKc_MOK	cd07831	3.6e-48	13	304
STKc_CDK1_like	cd07835	3.4e-66	13	304
STKc_CDK4_6_like	cd07838	1.8e-50	13	304
STKc_CDK9_like	cd07840	4.3e-75	13	304
STKc_MAK_like	cd07830	8.3e-64	13	304
PTKc_Csk_like	cd05039	4.7e-06	14	230
PKc_MAPKK	cd06605	1e-13	14	309
STKc_MAPKKK_Bck1_lik	cd06629	8.3e-13	14	304
PTKc_Tec_like	cd05059	1.1e-06	15	269
PK_STRAD_alpha	cd08227	0.00045	15	322
STKc_RSK_N	cd05582	1e-06	16	343
STKc_p70S6K	cd05584	3.9e-07	16	363
STKc_MEKK4	cd06626	3.4e-16	16	304
PTKc	cd00192	9.8e-12	17	262
PTKc_Ack_like	cd05040	6.1e-10	17	271
PTKc_Fes_like	cd05041	1.4e-08	17	267
PTKc_Aatyk	cd05042	4.3e-05	17	260
PTKc_c-ros	cd05044	4.6e-06	17	267
PTKc_Syk_like	cd05060	2e-06	17	266
PTKc_Met_Ron	cd05058	1.2e-05	17	267
PTKc_Fes	cd05084	1e-05	17	267
PTKc_Fer	cd05085	3.7e-05	17	267
PTKc_Syk	cd05116	6.4e-05	17	275
STKc_PKC	cd05570	4.9e-10	17	343
STKc_PKB	cd05571	2.2e-08	17	361
STKc_SGK	cd05575	6.7e-06	17	333
STKc_aPKC	cd05588	1.6e-07	17	337
STKc_nPKC_epsilon	cd05591	3.3e-08	17	344
STKc_nPKC_theta_delt	cd05592	5e-07	17	333
STKc_PKB_gamma	cd05593	6.9e-06	17	350
STKc_PKB_alpha	cd05594	5.3e-07	17	349
STKc_PKB_beta	cd05595	1.7e-05	17	317
STKc_nPKC_eta	cd05590	2.3e-06	17	342
STKc_SGK1	cd05602	0.00015	17	334
STKc_SGK2	cd05603	2.7e-06	17	356
STKc_SGK3	cd05604	0.00036	17	358
STKc_aPKC_zeta	cd05617	2.9e-06	17	337
STKc_aPKC_iota	cd05618	1.5e-05	17	337
STKc_nPKC_theta	cd05619	1.8e-07	17	363
STKc_nPKC_delta	cd05620	0.00074	17	363
PKc_MKK3_6	cd06617	3.8e-11	17	319
PKc_MAPKK_Pek1_like	cd06621	1.5e-08	17	319
PKc_MAPKK_PBS2_like	cd06622	1.5e-08	17	322
STKc_MEKK1	cd06630	8.2e-09	17	283
STKc_MEKK1_plant	cd06632	2.8e-14	17	304
PTKc_Zap-70	cd05115	7.4e-05	18	270
STKc_Sid2p_Dbf2p	cd05600	1.6e-07	18	369
PKc_MKK4	cd06616	8.4e-09	18	281
STKc_CDC2L6	cd07867	3.3e-15	18	304
STKc_CDK8	cd07868	1.7e-19	18	304
PKc	cd00180	1.2e-70	19	302
STKc_AGC	cd05123	5.4e-16	19	304
STKc_cGK_PKG	cd05572	2.1e-09	19	257
STKc_GRK	cd05577	2.5e-09	19	276
STKc_MAST_like	cd05579	5.2e-16	19	309
STKc_YPK1_like	cd05585	2.1e-08	19	337
STKc_Sck1_like	cd05586	2.7e-08	19	393
STKc_beta_ARK	cd05606	1.4e-06	19	290
STKc_GRK7	cd05607	3.9e-07	19	306
STKc_GRK1	cd05608	5.8e-07	19	306
STKc_GRK3	cd05633	8.2e-06	19	315
STKc_YSK4	cd06631	1.1e-10	19	304
STKc_NDR_like	cd05599	3.9e-06	20	339
STKc_Rim15_like	cd05611	3.4e-05	21	310
STKc_CDC2L1	cd07843	1.4e-50	22	304
Pkinase	pfam00069	9.4e-92	13	304
Pkinase_Tyr	pfam07714	4.6e-15	13	257
TyrKc	smart00219	1.7e-14	13	258
STYKc	smart00221	7.7e-91	13	304
S_TKc	smart00220	4e-96	23	304

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs61999265	Polymorphism	p.ALA54PRO	N/A
dbSNP	rs34410761	Polymorphism	p.PRO358LEU	N/A
Swiss-Prot	VAR_061536	Polymorphism	p.SER505PRO	N/A
dbSNP	rs60732298	Polymorphism	p.THR221LYS	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258