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Results for the Protein: Q9UHD2
74761953

TBK1_HUMAN RecName: Full=Serine/threonine-protein kinase TBK1; AltName: Full=NF-kappa-B-activating kinase; AltName: Full=T2K; AltName: Full=TANK-binding kinase 1
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Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

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Default View:

STKc_JNK - cd07850
STKc_PAK6 - cd06659
STKc_BUR1 - cd07866
STKc_PFTAIRE2 - cd07870
PTKc_EGFR_like - cd05057
STKc_p38gamma_MAPK12 - cd07880
STKc_MAP4K5 - cd06646
STKc_CDK10 - cd07845
STKc_MAP4K3 - cd06645
PTKc_InsR - cd05061
STKc_myosinIIIA - cd06638
PTKc_Tie2 - cd05088
STKc_myosinIIIB - cd06639
STKc_STK10_LOK - cd06644
PKc_MEK1 - cd06650
STKc_TNIK - cd06637
STKc_PAK2 - cd06655
STKc_CDK12 - cd07864
STKc_MAP4K4_6 - cd06636
STKc_p38 - cd07851
PKc_MEK2 - cd06649
PTKc_FAK - cd05056
STKc_TAO2 - cd06634
STKc_TAO - cd06607
PTKc_Musk - cd05050
STKc_PAK - cd06614
PKc_MKK7 - cd06618
PTKc_ALK_LTK - cd05036
PTKc_Hck - cd05073
STKc_PAK_I - cd06647
STKc_PAK1 - cd06654
PTKc_Src - cd05071
STKc_TEY_MAPK_plant - cd07858
STKc_SLK - cd06643
PTKc_Fyn_Yrk - cd05070
PTKc_Yes - cd05069
PTKc_Jak_rpt2 - cd05038
PTKc_Trk - cd05049
PTKc_IGF-1R - cd05062
PTKc_Frk_like - cd05068
STKc_MST3 - cd06641
PKc_MAPKK_Byr1_like - cd06620
STKc_STK25-YSK1 - cd06642
PKc_MKK4 - cd06616
STKc_CDK9 - cd07865
STKc_PCTAIRE_like - cd07844
STKc_PAK3 - cd06656
STKc_MST4 - cd06640
PTKc_EphR - cd05033
PTKc_Tec_Rlk - cd05114
PTKc_Jak1_rpt2 - cd05079
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_InsR_like - cd05032
PTKc_Btk_Bmx - cd05113
PTKc_Itk - cd05112
STKc_ASK - cd06624
STKc_MAP4K3_like - cd06613
STKc_MST1_2 - cd06612
PTKc_Csk_like - cd05039
STKc_MEKK3_like_1 - cd06653
STKc_PAK_II - cd06648
STKc_CDKL1_4 - cd07847
STKc_ERK1_2_like - cd07849
PK_STRAD - cd08216
PKc_MAPKK_plant_like - cd06623
STKc_CDKL5 - cd07848
PKc_MAPKK_Pek1_like - cd06621
STKc_myosinIII_like - cd06608
PKc_MAPKK_PBS2_like - cd06622
STKc_SLK_like - cd06611
STKc_phototropin_lik - cd05574
PKc_MEK - cd06615
PKc_MKK3_6 - cd06617
STKc_PCTAIRE3 - cd07871
STKc_MAPK - cd07834
STKc_PCTAIRE2 - cd07872
STKc_CDK6 - cd07862
STKc_Nek6_Nek7 - cd08224
STKc_NAK1_like - cd06917
SPS1 - COG0515
STKc_PCTAIRE1 - cd07873
PTKc_Ror - cd05048
STKc_DMPK_like - cd05597
PTKc_Tyk2_rpt2 - cd05080
STKc_MAPKKK_Bck1_lik - cd06629
STKc_MAST - cd05609
STKc_ROCK_NDR_like - cd05573
STKc_PRKX_like - cd05612
STKc_MRCK_beta - cd05624
STKc_MST3_like - cd06609
STKc_CDK7 - cd07841
STKc_Pho85 - cd07836
STKc_CCRK - cd07832
STKc_MAPKKK - cd06606
STKc_MPK1 - cd07857
Pkinase_Tyr - pfam07714
STKc_Nek10 - cd08528
STKc_Nek5 - cd08225
STKc_Nek4 - cd08223
STKc_TDY_MAPK_plant - cd07859
STKc_Cdc7_like - cd06627
STKc_GRK5 - cd05632
STKc_GRK4_like - cd05605
PKc_STE - cd05122
STKc_MEKK1_plant - cd06632
STKc_GRK4 - cd05631
PTKc_HER4 - cd05110
STKc_MEKK4 - cd06626
STKc_MEKK1 - cd06630
STKc_YSK4 - cd06631
STKc_MAPKKK_Byr2_lik - cd06628
STKc_CDK9_like - cd07840
STKc_Nek1 - cd08218
STKc_CDK4_6_like - cd07838
STKc_MOK - cd07831
STKc_MAK_like - cd07830
STKc_Nek3 - cd08219
STKc_CDK1_like - cd07835
STKc_FA2-like - cd08529
STKc_CDK_like - cd07829
Pkinase - pfam00069
TyrKc - smart00219
STYKc - smart00221
STKc_Nek7 - cd08229
STKc_Nek11 - cd08222
STKc_CDK1_euk - cd07861
STKc_MEKK2 - cd06652
STKc_cPKC - cd05587
STKc_PKN - cd05589
STKc_Yank1 - cd05578
PTKc_Srm_Brk - cd05148
PTKc_Src_like - cd05034
PTKc_Abl - cd05052
STKc_CRIK - cd05601
STKc_MSK_N - cd05583
STKc_MEKK3_like - cd06625
STKc_MSK1_N - cd05613
STKc_cPKC_alpha - cd05615
STKc_MRCK_alpha - cd05623
STKc_MEKK3 - cd06651
STKc_MSK2_N - cd05614
STKc_PKA - cd05580
STKc_CDK8_like - cd07842
STKc_OSR1_SPAK - cd06610
STKc_CNK2-like - cd08530
STKc_p70S6K - cd05584
PKc_MAPKK - cd06605
STKc_RSK_N - cd05582
STKc_SGK2 - cd05603
STKc_SGK3 - cd05604
STKc_aPKC_zeta - cd05617
STKc_nPKC_epsilon - cd05591
STKc_aPKC_iota - cd05618
STKc_PKB_beta - cd05595
STKc_SGK1 - cd05602
STKc_Nek2 - cd08217
STKc_Nek - cd08215
STKc_PKB_alpha - cd05594
STKc_CDK5 - cd07839
STKc_CDKL2_3 - cd07846
STKc_NDR1 - cd05628
STKc_CdkB_plant - cd07837
STKc_nPKC_theta - cd05619
PTKc_Fes - cd05084
PTKc_Met_Ron - cd05058
PTK_Jak2_Jak3_rpt1 - cd05078
PTKc_Fer - cd05085
PTKc - cd00192
STKc_PKB_gamma - cd05593
PTKc_c-ros - cd05044
PTKc_Fes_like - cd05041
PTKc_Ack_like - cd05040
PTKc_Syk - cd05116
PTKc_Tie - cd05047
STKc_PDK1 - cd05581
STKc_aPKC - cd05588
STKc_nPKC_eta - cd05590
STKc_nPKC_theta_delt - cd05592
STKc_CMGC - cd05118
STKc_SGK - cd05575
STKc_PKC - cd05570
STKc_PKB - cd05571
STKc_CDKL - cd07833
STKc_Nek8 - cd08220
STKc_Nek9 - cd08221
STKc_beta_ARK - cd05606
STKc_GRK1 - cd05608
STKc_MAST_like - cd05579
STKc_CDK4 - cd07863
STKc_GRK7 - cd05607
STKc_NLK - cd07853
PTKc_Tec_like - cd05059
STKc_Sck1_like - cd05586
STKc_AGC - cd05123
PTKc_Zap-70 - cd05115
PKc - cd00180
STKc_cGK_PKG - cd05572
STKc_YPK1_like - cd05585
STKc_GRK - cd05577
PTKc_Syk_like - cd05060
STKc_Rim15_like - cd05611
S_TKc - smart00220
STKc_CDC2L1 - cd07843


Swiss-Prot Protein: Q9UHD2
Identical to: NP_037386
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
PTKc_EGFR_likecd050570.000311283
PTKc_InsRcd050610.000481298
PTKc_Tie2cd050880.000241297
STKc_myosinIIIAcd066382.3e-051290
STKc_myosinIIIBcd066393.3e-051291
STKc_STK10_LOKcd066443.6e-071306
STKc_MAP4K3cd066455.9e-061295
STKc_MAP4K5cd066463.9e-051295
STKc_PAK6cd066590.00041305
STKc_CDK10cd078452e-051315
STKc_JNKcd078500.000941357
STKc_BUR1cd078662.2e-061299
STKc_PFTAIRE2cd078703.6e-061330
STKc_p38gamma_MAPK12cd078802.8e-051351
PTKc_ALK_LTKcd050361.1e-062259
PTKc_Muskcd050500.000442275
PTKc_FAKcd050566.3e-052289
STKc_TAOcd066070.00032327
STKc_PAKcd066143.1e-092238
PKc_MKK7cd066186.4e-072305
STKc_TAO2cd066340.000462309
STKc_MAP4K4_6cd066366.3e-052281
STKc_TNIKcd066376.3e-062281
PKc_MEK2cd066490.000252352
PKc_MEK1cd066500.000242347
STKc_PAK2cd066559.6e-052292
STKc_p38cd078510.000162329
STKc_CDK12cd078643e-062306
PTKc_Jak_rpt2cd050384.2e-073310
PTKc_Trkcd050491.4e-053287
PTKc_IGF-1Rcd050620.000113286
PTKc_Frk_likecd050685e-063276
PTKc_Yescd050690.000183280
PTKc_Fyn_Yrkcd050700.000633288
PTKc_Srccd050710.000293282
PTKc_Hckcd050730.000853288
STKc_PAK_Icd066470.00013300
STKc_SLKcd066432.3e-073289
STKc_PAK1cd066545.6e-053291
STKc_TEY_MAPK_plantcd078581.7e-053348
PTKc_InsR_likecd050324.2e-054286
PTKc_EphRcd050330.000184277
PTKc_Jak1_rpt2cd050790.000134306
PTKc_Jak2_Jak3_rpt2cd050814.1e-054289
PTKc_Itkcd051121.1e-064277
PTKc_Btk_Bmxcd051132.3e-074274
PTKc_Tec_Rlkcd051142.9e-054274
PKc_MKK4cd066163.8e-064306
PKc_MAPKK_Byr1_likecd066204.6e-064294
STKc_MST4cd066400.000324294
STKc_MST3cd066410.000234294
STKc_STK25-YSK1cd066420.000154294
STKc_PAK3cd066560.000154293
STKc_PCTAIRE_likecd078447.5e-074310
STKc_CDK9cd078652.1e-064260
PTKc_Csk_likecd050390.000595207
STKc_MST1_2cd066121.9e-125257
STKc_MAP4K3_likecd066136.6e-105251
STKc_ASKcd066242.4e-085281
STKc_phototropin_likcd055742.3e-086286
STKc_myosinIII_likecd066081.7e-096281
STKc_SLK_likecd066114.5e-076279
PKc_MEKcd066156.9e-076343
PKc_MKK3_6cd066170.000156286
PKc_MAPKK_Pek1_likecd066212.3e-086293
PKc_MAPKK_PBS2_likecd066222.1e-056276
PKc_MAPKK_plant_likecd066238e-126286
STKc_PAK_IIcd066487.7e-056285
STKc_MEKK3_like_1cd066536.2e-076275
STKc_CDKL1_4cd078478.6e-086325
STKc_CDKL5cd078487.2e-056310
STKc_ERK1_2_likecd078490.000356359
PK_STRADcd082160.000316283
PTKc_Rorcd050486.4e-057276
PTKc_Tyk2_rpt2cd050801e-057293
STKc_ROCK_NDR_likecd055733.3e-057301
STKc_DMPK_likecd055972e-067360
STKc_MASTcd056091.4e-067337
STKc_PRKX_likecd056128.9e-087296
STKc_MRCK_betacd056249.2e-057327
STKc_MST3_likecd066099.7e-097294
STKc_MAPKKK_Bck1_likcd066298e-067275
STKc_NAK1_likecd069173.4e-087289
STKc_MAPKcd078344.2e-067327
STKc_CDK6cd078620.000497310
STKc_PCTAIRE3cd078716.2e-067304
STKc_PCTAIRE2cd078727.4e-067317
STKc_PCTAIRE1cd078733.9e-057311
STKc_Nek6_Nek7cd082242.7e-057308
SPS1COG05152.4e-357469
PTKc_HER4cd051100.000768343
PKc_STEcd051222.2e-148252
STKc_GRK4_likecd056055e-068311
STKc_GRK5cd056320.000148302
STKc_GRK4cd056310.000418297
STKc_MEKK4cd066264.2e-128246
STKc_MAPKKK_Byr2_likcd066282e-078281
STKc_MEKK1cd066306.1e-088267
STKc_YSK4cd066312e-108281
STKc_MEKK1_plantcd066322.1e-098281
STKc_MAPKKKcd066062.2e-198281
STKc_Cdc7_likecd066271.3e-138260
STKc_CCRKcd078321.1e-098300
STKc_Pho85cd078362.3e-068304
STKc_CDK7cd078413.8e-088264
STKc_MPK1cd078570.000218313
STKc_TDY_MAPK_plantcd078593.5e-068337
STKc_Nek4cd082239.8e-068257
STKc_Nek5cd082251.7e-058281
STKc_Nek10cd085289.3e-068265
PTKc_Src_likecd050343.2e-069259
PTKc_Ablcd050528.7e-069277
PTKc_Srm_Brkcd051484.8e-079257
STKc_Yank1cd055781.6e-109296
STKc_MSK_Ncd055831.5e-079316
STKc_cPKCcd055870.00039329
STKc_PKNcd055892.4e-069298
STKc_CRIKcd056011.5e-069305
STKc_MSK1_Ncd056137.4e-069316
STKc_MSK2_Ncd056141.1e-069362
STKc_cPKC_alphacd056150.000339327
STKc_MRCK_alphacd056230.000159328
STKc_MEKK3_likecd066252.2e-109275
STKc_MEKK3cd066513.6e-099284
STKc_MEKK2cd066522.1e-069283
STKc_CDK_likecd078298.2e-119287
STKc_MAK_likecd078308.5e-099330
STKc_MOKcd078312.7e-089330
STKc_CDK1_likecd078350.000749330
STKc_CDK4_6_likecd078381.4e-079299
STKc_CDK9_likecd078401.2e-089251
STKc_CDK1_eukcd078618.4e-059330
STKc_Nek1cd082181.7e-059290
STKc_Nek3cd082191.5e-079274
STKc_Nek11cd082220.000259257
STKc_Nek7cd082292.6e-059275
STKc_FA2-likecd085291.5e-079281
STKc_PKAcd055801.3e-0710298
STKc_OSR1_SPAKcd066105.7e-1111281
STKc_CDK8_likecd078420.0004811299
STKc_CNK2-likecd085304.3e-0611282
STKc_RSK_Ncd055821.5e-0612360
STKc_p70S6Kcd055843.7e-0612369
PKc_MAPKKcd066051.7e-1012254
PTKccd001921.9e-0713274
PTKc_Ack_likecd050401.2e-0713252
PTKc_Fes_likecd050412.7e-0813252
PTKc_c-roscd050440.0006713287
PTKc_Tiecd050470.0006813274
PTKc_Met_Roncd050580.0006813287
PTK_Jak2_Jak3_rpt1cd050780.0009813274
PTKc_Fescd050842.1e-0513278
PTKc_Fercd050855.3e-0513275
PTKc_Sykcd051161.1e-0513281
STKc_CMGCcd051183.3e-1113281
STKc_PKCcd055703.2e-0913298
STKc_PKBcd055711.6e-0713357
STKc_SGKcd055759e-0513373
STKc_PDK1cd055815.1e-1113299
STKc_aPKCcd055881.1e-0513361
STKc_nPKC_etacd055904.5e-0513328
STKc_nPKC_theta_deltcd055920.0001113329
STKc_PKB_gammacd055932e-0513385
STKc_PKB_alphacd055945.6e-0613344
STKc_nPKC_epsiloncd055913.2e-0513331
STKc_PKB_betacd055951.1e-0513343
STKc_SGK1cd056020.000213385
STKc_SGK2cd056036.8e-0613342
STKc_SGK3cd056040.0007513375
STKc_aPKC_zetacd056175.8e-0513342
STKc_aPKC_iotacd056180.0006513327
STKc_nPKC_thetacd056191.7e-0613328
STKc_NDR1cd056280.0003113344
STKc_CdkB_plantcd078372.4e-0613296
STKc_CDKL2_3cd078463.5e-0813330
STKc_CDK5cd078396.2e-0613296
STKc_Nekcd082151.5e-1413258
STKc_Nek2cd082177.3e-0913246
STKc_beta_ARKcd056060.0002614326
STKc_CDKLcd078333.3e-0814298
STKc_Nek8cd082201.5e-0514304
STKc_Nek9cd082213.8e-0614306
PKccd001805.3e-6815328
PTKc_Tec_likecd050599.8e-0715274
PTKc_Syk_likecd050600.0001515274
PTKc_Zap-70cd051151.3e-0515278
STKc_AGCcd051234e-1415325
STKc_cGK_PKGcd055723.3e-0915261
STKc_GRKcd055771.5e-0615283
STKc_YPK1_likecd055858e-0515329
STKc_Sck1_likecd055862.7e-0515375
STKc_GRK7cd056072.7e-0515310
STKc_GRK1cd056086e-0815301
STKc_MAST_likecd055792.8e-1115259
STKc_NLKcd078530.0004915357
STKc_CDK4cd078633.3e-0515315
STKc_Rim15_likecd056110.0004117332
STKc_CDC2L1cd078439.4e-0622281
Pkinasepfam000691.7e-379281
Pkinase_Tyrpfam077141.1e-098277
TyrKcsmart002191.6e-109263
STYKcsmart002212.5e-419294
S_TKcsmart002201.3e-4119310

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_041208Polymorphismp.ARG271GLNN/A
Swiss-ProtVAR_024746Polymorphismp.ASN388ASPN/A
Swiss-ProtVAR_041210Polymorphismp.ASP296HISN/A
Swiss-ProtVAR_041211Polymorphismp.GLY410ARGN/A
Swiss-ProtVAR_069755Polymorphismp.LEU306ILEN/A
Swiss-ProtVAR_024747Polymorphismp.LYS570GLNN/A
Swiss-ProtVAR_041209Polymorphismp.LYS291GLUN/A
Swiss-ProtVAR_069754Polymorphismp.SER151PHEN/A
Swiss-ProtVAR_041212Polymorphismp.VAL464ALAN/A



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