Results for the protein: Q5MAI5

Results for the Protein: Q5MAI5

74762208

344387

CDKL4

NCBI, UniProt

CDKL4_HUMAN RecName: Full=Cyclin-dependent kinase-like 4

			0 6 0 0 6

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Swiss-Prot Protein: Q5MAI5

Identical to: NP_001009565

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_Csk_like	cd05039	0.00021	1	227
PTKc_Ror	cd05048	3.3e-07	1	217
PTKc_Abl	cd05052	1.6e-08	1	259
PTKc_EGFR_like	cd05057	0.00038	1	238
PTKc_Tec_like	cd05059	2.6e-09	1	285
PTKc_InsR	cd05061	0.00043	1	294
PTKc_EphR_B	cd05065	0.0005	1	263
PTKc_EphR_A	cd05066	0.00084	1	263
PTKc_Lck_Blk	cd05067	2.9e-06	1	289
PTKc_Frk_like	cd05068	1.3e-07	1	255
PTKc_Yes	cd05069	3.7e-05	1	258
PTKc_Fyn_Yrk	cd05070	3.6e-05	1	258
PTKc_Src	cd05071	0.00043	1	253
PTKc_Lyn	cd05072	4.1e-06	1	289
PTKc_Hck	cd05073	5.7e-06	1	258
PTKc_Tyro3	cd05074	0.0003	1	259
PTKc_Jak1_rpt2	cd05079	1.5e-05	1	290
PTKc_Tyk2_rpt2	cd05080	1.5e-05	1	257
PTKc_Chk	cd05083	9.8e-05	1	255
PTKc_Ror1	cd05090	3.2e-05	1	262
PTKc_Ror2	cd05091	3.9e-05	1	262
PTKc_TrkA	cd05092	4.1e-05	1	261
PTKc_TrkB	cd05093	1.8e-05	1	261
PTKc_DDR_like	cd05097	7.3e-05	1	261
PTKc_Csk	cd05082	0.00097	1	287
PTKc_DDR2	cd05095	3.9e-05	1	261
PTKc_Tec_Rlk	cd05114	2.5e-07	1	256
PTKc_Btk_Bmx	cd05113	1.6e-08	1	256
STKc_SLK_like	cd06611	1.1e-12	1	301
STKc_MAP4K3_like	cd06613	2.6e-16	1	285
PKc_MKK4	cd06616	9.4e-09	1	311
PKc_MKK7	cd06618	9.9e-11	1	313
STKc_ASK	cd06624	4.4e-11	1	286
STKc_myosinIIIA	cd06638	3.2e-08	1	260
STKc_myosinIIIB	cd06639	7.2e-08	1	264
STKc_STK10_LOK	cd06644	7.6e-09	1	306
STKc_MAP4K3	cd06645	1.8e-12	1	258
STKc_MAP4K5	cd06646	6.8e-10	1	285
STKc_PAK_I	cd06647	3.7e-16	1	301
STKc_PAK1	cd06654	1.1e-09	1	301
STKc_PAK2	cd06655	1.1e-09	1	305
STKc_PAK3	cd06656	3.2e-10	1	303
STKc_PAK5	cd06658	7.2e-07	1	274
STKc_PAK6	cd06659	4.1e-09	1	277
STKc_PCTAIRE_like	cd07844	7e-70	1	286
STKc_CDK10	cd07845	9.3e-51	1	290
STKc_JNK	cd07850	6.5e-17	1	310
STKc_MAPK15	cd07852	9.1e-35	1	310
STKc_TEY_MAPK_plant	cd07858	1.2e-53	1	315
STKc_CDK12	cd07864	8.5e-53	1	286
STKc_CDK9	cd07865	2.1e-45	1	286
STKc_BUR1	cd07866	3.4e-38	1	286
STKc_CDC2L6	cd07867	2.8e-21	1	286
STKc_CDK8	cd07868	2.9e-23	1	286
STKc_PFTAIRE1	cd07869	5.1e-39	1	298
STKc_PFTAIRE2	cd07870	3.3e-48	1	286
STKc_PCTAIRE2	cd07872	2e-39	1	307
STKc_PCTAIRE1	cd07873	3e-48	1	298
STKc_JNK3	cd07874	2.7e-10	1	312
STKc_JNK1	cd07875	1.4e-08	1	314
STKc_JNK2	cd07876	2.4e-11	1	312
STKc_PCTAIRE3	cd07871	3.3e-50	1	286
STKc_p38gamma_MAPK12	cd07880	7.6e-27	1	315
STKc_Nek6_Nek7	cd08224	1.8e-09	1	264
STKc_Nek6	cd08228	3.4e-07	1	264
STKc_Nek7	cd08229	3.6e-09	1	257
PTKc_Src_like	cd05034	2.3e-07	2	255
PTKc_ALK_LTK	cd05036	4.2e-05	2	254
PTKc_Musk	cd05050	4.6e-06	2	283
PTKc_DDR	cd05051	0.00071	2	291
PTKc_FGFR	cd05053	1.4e-06	2	229
PTKc_FAK	cd05056	4.1e-06	2	260
PTKc_FGFR4	cd05099	6.6e-05	2	283
PTKc_Itk	cd05112	2.7e-07	2	256
PTKc_Srm_Brk	cd05148	6.1e-07	2	284
STKc_ROCK_NDR_like	cd05573	7.4e-10	2	312
STKc_phototropin_lik	cd05574	2.9e-08	2	247
STKc_PKA	cd05580	1.9e-11	2	255
STKc_PDK1	cd05581	1.8e-17	2	286
STKc_DMPK_like	cd05597	3.6e-05	2	315
STKc_LATS	cd05598	0.00023	2	312
STKc_NDR_like	cd05599	1.6e-05	2	267
STKc_Sid2p_Dbf2p	cd05600	4e-07	2	314
STKc_CRIK	cd05601	4.2e-06	2	290
STKc_MAST	cd05609	2.1e-07	2	314
STKc_PRKX_like	cd05612	2.1e-08	2	290
STKc_MRCK_alpha	cd05623	3.2e-05	2	296
STKc_MRCK_beta	cd05624	0.0005	2	302
STKc_NDR1	cd05628	0.00056	2	307
PKc_MAPKK	cd06605	8.7e-17	2	291
STKc_TAO	cd06607	7.5e-10	2	313
STKc_myosinIII_like	cd06608	6.2e-12	2	286
STKc_MST3_like	cd06609	1.8e-16	2	307
STKc_OSR1_SPAK	cd06610	2.4e-14	2	286
STKc_MST1_2	cd06612	1.6e-17	2	286
STKc_PAK	cd06614	4.6e-21	2	298
PKc_MEK	cd06615	2.4e-13	2	298
PKc_MKK3_6	cd06617	7.5e-10	2	303
PKc_MKK5	cd06619	1.2e-08	2	309
PKc_MAPKK_Byr1_like	cd06620	7.2e-12	2	298
PKc_MAPKK_Pek1_like	cd06621	7.9e-12	2	295
PKc_MAPKK_PBS2_like	cd06622	2.6e-09	2	307
PKc_MAPKK_plant_like	cd06623	1.6e-20	2	291
STKc_TAO3	cd06633	7e-07	2	290
STKc_TAO2	cd06634	1.9e-10	2	301
STKc_TAO1	cd06635	8.9e-09	2	313
STKc_MST3	cd06641	4.8e-08	2	293
STKc_MST4	cd06640	8.2e-08	2	293
STKc_STK25-YSK1	cd06642	1e-08	2	301
STKc_SLK	cd06643	9.8e-10	2	304
STKc_PAK_II	cd06648	2.7e-10	2	263
PKc_MEK2	cd06649	2.6e-08	2	313
PKc_MEK1	cd06650	2e-07	2	315
STKc_MEKK3_like_1	cd06653	9.9e-08	2	259
STKc_PAK4	cd06657	4.3e-07	2	276
STKc_NAK1_like	cd06917	1.3e-13	2	295
STKc_CDKL	cd07833	1.2e-181	2	286
STKc_CdkB_plant	cd07837	2.6e-66	2	287
STKc_CDKL2_3	cd07846	2.5e-178	2	286
STKc_CDKL1_4	cd07847	7.1e-185	2	286
STKc_CDC2L1	cd07843	3.8e-47	2	286
STKc_CDKL5	cd07848	1.6e-91	2	286
STKc_ERK1_2_like	cd07849	2.2e-24	2	315
STKc_p38	cd07851	1e-19	2	315
STKc_ERK5	cd07855	3.7e-21	2	314
STKc_Sty1_Hog1	cd07856	1.2e-31	2	306
STKc_CDK6	cd07862	1.8e-48	2	286
STKc_p38alpha_MAPK14	cd07877	1.3e-25	2	315
STKc_p38delta_MAPK13	cd07879	2.5e-27	2	315
STKc_p38beta_MAPK11	cd07878	1e-25	2	315
PK_STRAD	cd08216	1.8e-08	2	315
SPS1	COG0515	5.1e-41	2	315
PTKc_EphR	cd05033	1.1e-05	3	221
PTKc_Trk	cd05049	3.8e-06	3	291
PTKc_FGFR3	cd05100	0.00089	3	279
PTKc_FGFR2	cd05101	0.00027	3	244
PKc_STE	cd05122	4.5e-31	3	285
STKc_Yank1	cd05578	2.1e-14	3	286
STKc_MSK_N	cd05583	8.4e-08	3	305
STKc_cPKC	cd05587	2.5e-06	3	293
STKc_GRK4_like	cd05605	1.3e-07	3	288
STKc_MSK2_N	cd05614	9.2e-06	3	312
STKc_cPKC_alpha	cd05615	1.2e-06	3	293
STKc_cPKC_beta	cd05616	4e-05	3	293
STKc_GRK6	cd05630	0.0001	3	312
STKc_GRK4	cd05631	3.5e-05	3	310
STKc_GRK5	cd05632	9e-06	3	273
STKc_MSK1_N	cd05613	1.4e-05	3	308
STKc_MAPKKK	cd06606	2.8e-37	3	286
STKc_MEKK4	cd06626	1.1e-17	3	286
STKc_Cdc7_like	cd06627	1.4e-18	3	286
STKc_MAPKKK_Byr2_lik	cd06628	2.6e-21	3	253
STKc_MEKK1	cd06630	7.6e-11	3	287
STKc_YSK4	cd06631	4.2e-11	3	286
STKc_MEKK3	cd06651	1.4e-09	3	255
STKc_CCRK	cd07832	4e-75	3	287
STKc_MAPK	cd07834	5.5e-50	3	301
STKc_Pho85	cd07836	8.2e-71	3	286
STKc_CDK5	cd07839	3.3e-76	3	286
STKc_CDK7	cd07841	3.5e-69	3	295
STKc_CDK8_like	cd07842	2.8e-35	3	286
STKc_NLK	cd07853	6.1e-16	3	314
STKc_MAPK4_6	cd07854	2.1e-16	3	302
STKc_MPK1	cd07857	3.8e-26	3	310
STKc_TDY_MAPK_plant	cd07859	3.8e-52	3	315
STKc_CDK2_3	cd07860	1e-72	3	286
STKc_CDK1_euk	cd07861	6.7e-75	3	286
STKc_CDK4	cd07863	3.8e-48	3	286
STKc_Nek	cd08215	2.5e-20	3	286
STKc_Nek2	cd08217	6.4e-18	3	286
STKc_Nek1	cd08218	8.6e-22	3	253
STKc_Nek3	cd08219	1.2e-12	3	253
STKc_Nek8	cd08220	8e-10	3	286
STKc_Nek9	cd08221	1.4e-10	3	286
STKc_Nek11	cd08222	2.2e-07	3	268
STKc_Nek4	cd08223	2.2e-09	3	257
STKc_Nek5	cd08225	5.5e-12	3	272
STKc_Nek10	cd08528	2e-07	3	254
STKc_FA2-like	cd08529	8e-13	3	286
STKc_CNK2-like	cd08530	4.6e-11	3	286
PTKc_Jak_rpt2	cd05038	7.5e-08	4	290
PTKc_Jak2_Jak3_rpt2	cd05081	2.2e-08	4	290
STKc_CMGC	cd05118	5.3e-149	4	286
STKc_PKN	cd05589	3.8e-07	4	310
STKc_MAP4K4_6	cd06636	2.3e-06	4	253
STKc_TNIK	cd06637	1e-07	4	259
STKc_CDK_like	cd07829	3.5e-98	4	286
STKc_MAK_like	cd07830	2.4e-84	4	286
STKc_MOK	cd07831	2.1e-36	4	286
STKc_CDK1_like	cd07835	9.8e-75	4	286
STKc_CDK4_6_like	cd07838	3.2e-42	4	286
STKc_CDK9_like	cd07840	3.9e-66	4	286
PK_STRAD_beta	cd08226	8.8e-05	5	303
PK_STRAD_alpha	cd08227	0.00057	5	308
PTKc_RET	cd05045	4.8e-05	6	252
STKc_PKB_gamma	cd05593	1.7e-07	6	297
STKc_PKB_alpha	cd05594	1e-07	6	315
STKc_PKB_beta	cd05595	4.6e-07	6	297
STKc_MEKK3_like	cd06625	1.6e-13	6	286
STKc_MEKK2	cd06652	5.5e-07	6	256
STKc_p70S6K	cd05584	1.2e-07	7	312
STKc_RSK_N	cd05582	5.7e-06	7	315
PTKc	cd00192	2.1e-11	8	285
PTKc_Fes_like	cd05041	4.7e-09	8	286
PTKc_Aatyk	cd05042	4.4e-05	8	262
PTKc_Met_Ron	cd05058	0.00021	8	261
PTKc_Syk_like	cd05060	5.1e-06	8	219
PTKc_Ack_like	cd05040	1.2e-09	8	288
PTKc_Fes	cd05084	2.3e-07	8	261
PTKc_Fer	cd05085	9e-07	8	257
PTKc_Zap-70	cd05115	1.3e-05	8	257
PTKc_Syk	cd05116	1.2e-06	8	257
STKc_PKB	cd05571	1.4e-09	8	315
STKc_nPKC_eta	cd05590	2.4e-05	8	315
STKc_nPKC_epsilon	cd05591	1.4e-07	8	309
STKc_nPKC_theta_delt	cd05592	2.8e-07	8	294
STKc_aPKC	cd05588	7.5e-08	8	293
STKc_SGK2	cd05603	6e-07	8	293
STKc_SGK3	cd05604	0.00027	8	288
STKc_nPKC_theta	cd05619	2.9e-09	8	297
STKc_nPKC_delta	cd05620	0.00041	8	294
STKc_SGK	cd05575	4e-06	9	292
PKc	cd00180	3.4e-73	10	284
STKc_AGC	cd05123	2.4e-16	10	286
STKc_cGK_PKG	cd05572	8.1e-11	10	293
STKc_GRK	cd05577	8.1e-09	10	272
STKc_MAST_like	cd05579	1e-13	10	291
STKc_YPK1_like	cd05585	3.5e-08	10	315
STKc_Sck1_like	cd05586	5.3e-06	10	315
STKc_SGK1	cd05602	3.1e-05	10	294
STKc_GRK7	cd05607	1.2e-07	10	288
STKc_GRK1	cd05608	4.5e-08	10	272
STKc_aPKC_zeta	cd05617	2.1e-08	10	293
STKc_aPKC_iota	cd05618	1.4e-06	10	311
STKc_GRK3	cd05633	0.0004	10	289
STKc_beta_ARK	cd05606	2.1e-05	10	272
PTK_Jak_rpt1	cd05037	0.00076	11	232
PTKc_c-ros	cd05044	9.8e-05	11	283
STKc_PKC	cd05570	9.8e-11	11	292
STKc_MAPKKK_Bck1_lik	cd06629	1.5e-15	11	286
STKc_MEKK1_plant	cd06632	1.3e-13	11	286
Pkinase	pfam00069	4.3e-106	4	286
Pkinase_Tyr	pfam07714	7.5e-16	4	286
TyrKc	smart00219	7.7e-15	4	286
STYKc	smart00221	1.7e-91	4	286
S_TKc	smart00220	4.8e-102	14	286
KIND	smart00750	9.7e-05	97	294

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041996	Polymorphism	p.ARG307CYS	N/A
Swiss-Prot	VAR_041993	Polymorphism	p.ARG53HIS	N/A
Swiss-Prot	VAR_053930	Polymorphism	p.HIS118TYR	N/A
Swiss-Prot	VAR_041994	Polymorphism	p.PHE228CYS	N/A
Swiss-Prot	VAR_041992	Polymorphism	p.SER38PRO	N/A
Swiss-Prot	VAR_041995	Polymorphism	p.SER288TYR	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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