Results for the protein: Q8NE63

Results for the Protein: Q8NE63

74762559

147746

HIPK4

NCBI, UniProt

HIPK4_HUMAN RecName: Full=Homeodomain-interacting protein kinase 4

			0 8 0 0 8

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Swiss-Prot Protein: Q8NE63

Identical to: NP_653286

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_PAK	cd06614	3.8e-09	1	285
STKc_TAO1	cd06635	0.00052	1	290
STKc_MAP4K4_6	cd06636	0.00049	1	275
STKc_myosinIIIA	cd06638	7.3e-06	1	284
STKc_myosinIIIB	cd06639	3.8e-06	1	277
STKc_STK10_LOK	cd06644	1.7e-05	1	293
STKc_MAP4K3	cd06645	0.00032	1	265
STKc_PAK_I	cd06647	6.2e-05	1	293
STKc_PAK_II	cd06648	0.00013	1	288
STKc_PAK2	cd06655	0.00024	1	298
STKc_PAK3	cd06656	0.00016	1	302
STKc_PAK4	cd06657	0.00011	1	285
STKc_PAK5	cd06658	0.0003	1	283
STKc_PAK6	cd06659	0.0005	1	298
STKc_PAK1	cd06654	0.00021	1	295
STKc_p38	cd07851	2.2e-13	1	379
STKc_JNK	cd07850	1.9e-11	1	384
STKc_Sty1_Hog1	cd07856	6.3e-10	1	331
STKc_JNK1	cd07875	9e-08	1	331
STKc_p38gamma_MAPK12	cd07880	9.7e-10	1	338
PTKc_EGFR_like	cd05057	3.9e-05	2	281
PTKc_HER2	cd05109	9.2e-05	2	286
PTK_HER3	cd05111	0.00013	2	281
STKc_ASK	cd06624	4.2e-06	2	275
STKc_JNK3	cd07874	2.9e-09	2	408
STKc_JNK2	cd07876	9.1e-09	2	349
STKc_p38alpha_MAPK14	cd07877	4.4e-09	2	338
STKc_p38beta_MAPK11	cd07878	1.6e-09	2	338
STKc_p38delta_MAPK13	cd07879	1.1e-05	2	389
PTKc_Trk	cd05049	0.00015	3	272
PTKc_Src	cd05071	4.3e-05	3	271
PTKc_Yes	cd05069	1.1e-05	3	269
PTKc_EGFR	cd05108	0.00018	3	329
PKc_MKK7	cd06618	0.00032	3	276
STKc_MAP4K5	cd06646	0.00038	3	274
STKc_CDK9	cd07865	2.3e-11	3	347
PTKc_ALK_LTK	cd05036	9.2e-06	4	263
PTKc_FAK	cd05056	3.8e-05	4	275
PTKc_Lck_Blk	cd05067	5.9e-05	4	291
PTKc_Frk_like	cd05068	1.2e-07	4	269
PTKc_Fyn_Yrk	cd05070	3.4e-05	4	269
PTKc_Lyn	cd05072	5.2e-05	4	270
PTKc_Hck	cd05073	0.0003	4	269
STKc_TNIK	cd06637	8.5e-05	4	275
STKc_TEY_MAPK_plant	cd07858	1.5e-15	4	332
PKc_MEK2	cd06649	0.00026	5	339
PKc_MEK1	cd06650	0.0004	5	359
STKc_SLK	cd06643	8.3e-06	5	293
STKc_PCTAIRE_like	cd07844	4.8e-17	5	308
STKc_ERK5	cd07855	4.6e-11	5	387
STKc_CDK12	cd07864	4.1e-12	5	347
PTKc_Jak_rpt2	cd05038	0.00011	6	271
PKc_MKK4	cd06616	8.2e-06	6	267
STKc_TAO2	cd06634	4.7e-05	6	291
STKc_MST4	cd06640	5.3e-06	6	295
STKc_MST3	cd06641	1.1e-05	6	295
STKc_STK25-YSK1	cd06642	9.2e-07	6	295
STKc_BUR1	cd07866	1.9e-10	6	347
STKc_PFTAIRE1	cd07869	1.1e-05	6	316
STKc_PFTAIRE2	cd07870	7.6e-08	6	302
STKc_PCTAIRE3	cd07871	4.7e-08	6	308
STKc_PCTAIRE2	cd07872	1.1e-07	6	365
STKc_PCTAIRE1	cd07873	3.4e-07	6	322
PTKc_InsR_like	cd05032	7.9e-06	7	280
PTKc_Musk	cd05050	0.00034	7	251
PTKc_Abl	cd05052	2.6e-06	7	265
PTKc_EphR_B	cd05065	0.00014	7	271
PTKc_Jak2_Jak3_rpt2	cd05081	4.5e-06	7	292
PTKc_Chk	cd05083	0.00089	7	264
PTKc_TrkA	cd05092	0.00071	7	272
PTKc_Itk	cd05112	6.9e-06	7	267
PTKc_Btk_Bmx	cd05113	8.1e-06	7	271
PTKc_Tec_Rlk	cd05114	8.3e-05	7	271
PTKc_Csk	cd05082	0.00099	7	273
STKc_MAP4K3_like	cd06613	1.1e-08	7	261
PTKc_Tec_like	cd05059	1.5e-05	8	271
STKc_myosinIII_like	cd06608	3.3e-06	8	249
STKc_SLK_like	cd06611	2.2e-05	8	291
PKc_MAPKK_plant_like	cd06623	5.6e-10	8	268
STKc_MEKK3_like_1	cd06653	0.00015	8	276
STKc_CDK10	cd07845	4.2e-12	8	260
STKc_ERK1_2_like	cd07849	1.5e-10	8	379
STKc_Nek6_Nek7	cd08224	1.7e-07	8	272
STKc_Nek7	cd08229	8e-06	8	269
STKc_ROCK_NDR_like	cd05573	2.4e-06	9	306
STKc_PKA	cd05580	3.2e-07	9	269
STKc_PDK1	cd05581	1e-13	9	249
STKc_Sid2p_Dbf2p	cd05600	9.1e-06	9	307
STKc_CRIK	cd05601	0.00019	9	284
STKc_NDR_like	cd05599	0.00044	9	298
STKc_DMPK_like	cd05597	0.00059	9	352
STKc_MAST	cd05609	0.00072	9	331
STKc_PRKX_like	cd05612	0.00011	9	270
STKc_NDR1	cd05628	0.00081	9	334
STKc_NDR_like_fungal	cd05629	0.00089	9	355
PKc_MAPKK	cd06605	1.5e-06	9	254
STKc_OSR1_SPAK	cd06610	4.6e-07	9	249
PKc_MEK	cd06615	9.2e-07	9	328
PKc_MKK3_6	cd06617	3.9e-07	9	266
STKc_MST1_2	cd06612	2e-09	9	249
PKc_MKK5	cd06619	0.0009	9	315
PKc_MAPKK_PBS2_like	cd06622	1.6e-06	9	331
STKc_MST3_like	cd06609	7.3e-07	9	286
STKc_NAK1_like	cd06917	1.8e-08	9	274
STKc_CDKL	cd07833	1.9e-16	9	284
STKc_CdkB_plant	cd07837	4.3e-16	9	348
STKc_CDC2L1	cd07843	1.6e-13	9	347
STKc_CDKL2_3	cd07846	2.2e-13	9	347
STKc_CDKL1_4	cd07847	2.3e-32	9	305
STKc_CDKL5	cd07848	1.8e-14	9	305
STKc_CDK6	cd07862	1.1e-07	9	305
SPS1	COG0515	2e-42	9	507
PKc_STE	cd05122	1.4e-14	10	261
STKc_Yank1	cd05578	3.7e-08	10	262
STKc_GRK4_like	cd05605	5.2e-06	10	308
STKc_GRK4	cd05631	0.00063	10	302
STKc_GRK5	cd05632	0.00042	10	277
STKc_cPKC_alpha	cd05615	4.2e-05	10	322
STKc_MAPKKK	cd06606	2.7e-14	10	262
STKc_Cdc7_like	cd06627	4e-13	10	262
STKc_MEKK3	cd06651	0.0001	10	278
STKc_CCRK	cd07832	2.1e-17	10	348
STKc_CDK7	cd07841	7.7e-16	10	353
STKc_CDK8_like	cd07842	1.2e-10	10	347
STKc_CDK5	cd07839	3.4e-10	10	284
STKc_MAPK	cd07834	7.2e-16	10	376
STKc_Pho85	cd07836	4.1e-22	10	305
STKc_NLK	cd07853	9e-09	10	417
STKc_MPK1	cd07857	1.6e-11	10	377
STKc_TDY_MAPK_plant	cd07859	3.6e-17	10	345
STKc_CDK2_3	cd07860	4.2e-23	10	305
STKc_CDK4	cd07863	6.7e-17	10	293
STKc_Nek2	cd08217	5.4e-10	10	266
STKc_Nek8	cd08220	3.5e-05	10	275
STKc_Nek9	cd08221	6.6e-06	10	263
STKc_Nek11	cd08222	0.0006	10	270
STKc_Nek4	cd08223	1.8e-05	10	270
STKc_Nek5	cd08225	1.4e-05	10	270
STKc_Nek	cd08215	7.4e-10	10	233
STKc_Nek10	cd08528	9.4e-08	10	271
STKc_CNK2-like	cd08530	4e-07	10	268
PTKc_Axl_like	cd05035	0.00016	11	271
PTKc_Srm_Brk	cd05148	2e-07	11	266
STKc_CMGC	cd05118	4.6e-39	11	347
STKc_MSK_N	cd05583	3.6e-05	11	281
STKc_cPKC	cd05587	2.6e-06	11	340
STKc_PKN	cd05589	0.00015	11	342
STKc_MSK2_N	cd05614	0.00034	11	349
STKc_cPKC_beta	cd05616	6.1e-05	11	321
STKc_MAPKKK_Bck1_lik	cd06629	3.8e-07	11	243
STKc_CDK_like	cd07829	1.1e-23	11	347
STKc_MAK_like	cd07830	2.2e-22	11	347
STKc_MOK	cd07831	1.1e-19	11	347
STKc_CDK1_like	cd07835	3e-24	11	305
STKc_CDK4_6_like	cd07838	2.9e-15	11	347
STKc_CDK9_like	cd07840	1.2e-15	11	347
STKc_MAPK4_6	cd07854	2.6e-07	11	331
STKc_MAPK15	cd07852	1e-15	11	377
STKc_CDK1_euk	cd07861	7.8e-20	11	347
STKc_CDC2L6	cd07867	5.2e-07	11	305
STKc_CDK8	cd07868	9.1e-07	11	305
STKc_Nek1	cd08218	1.6e-05	11	268
STKc_Nek3	cd08219	5.3e-10	11	268
STKc_Nek6	cd08228	4.2e-05	11	269
STKc_FA2-like	cd08529	4.5e-08	11	266
PTKc_Src_like	cd05034	1.2e-06	12	252
PTKc_Zap-70	cd05115	7.8e-05	14	269
STKc_RSK_N	cd05582	8.7e-05	14	352
STKc_p70S6K	cd05584	5e-06	14	354
PTKc	cd00192	3.8e-06	15	250
PTKc_Ack_like	cd05040	1.1e-06	15	272
PTKc_c-ros	cd05044	8.8e-06	15	263
PTKc_Met_Ron	cd05058	2.9e-05	15	273
PTKc_Syk_like	cd05060	7.8e-06	15	254
PTKc_Fer	cd05085	0.00017	15	272
PTKc_Syk	cd05116	2.3e-06	15	270
STKc_PKC	cd05570	6.9e-07	15	299
STKc_PKB	cd05571	7.2e-06	15	349
STKc_SGK	cd05575	4.5e-05	15	362
STKc_aPKC	cd05588	0.00017	15	337
STKc_nPKC_eta	cd05590	2.9e-05	15	340
STKc_nPKC_epsilon	cd05591	4e-07	15	340
STKc_nPKC_theta_delt	cd05592	9.6e-07	15	338
STKc_PKB_gamma	cd05593	0.00033	15	368
STKc_PKB_alpha	cd05594	6.3e-06	15	339
STKc_PKB_beta	cd05595	0.00026	15	341
STKc_SGK1	cd05602	0.00017	15	364
STKc_SGK2	cd05603	1.9e-06	15	351
STKc_nPKC_theta	cd05619	6e-06	15	329
STKc_nPKC_delta	cd05620	0.00027	15	338
STKc_MEKK3_like	cd06625	4.2e-07	15	275
STKc_MAPKKK_Byr2_lik	cd06628	4.2e-07	15	275
STKc_MEKK1	cd06630	5.3e-05	15	250
STKc_YSK4	cd06631	1.2e-07	15	270
STKc_MEKK1_plant	cd06632	3e-07	15	257
PKc	cd00180	1e-47	17	345
STKc_AGC	cd05123	3.3e-09	17	249
STKc_cGK_PKG	cd05572	1.6e-07	17	256
STKc_GRK	cd05577	2.5e-05	17	256
STKc_MAST_like	cd05579	1.3e-08	17	250
STKc_YPK1_like	cd05585	3.5e-06	17	330
STKc_Sck1_like	cd05586	9.2e-05	17	392
STKc_GRK7	cd05607	5.7e-05	17	307
STKc_GRK1	cd05608	7.2e-05	17	295
STKc_MEKK4	cd06626	1.4e-07	17	262
STKc_aPKC_zeta	cd05617	0.00025	30	337
Pkinase	pfam00069	2e-40	11	347
Pkinase_Tyr	pfam07714	7.8e-10	11	249
TyrKc	smart00219	1.8e-08	11	263
STYKc	smart00221	3e-57	11	347
S_TKc	smart00220	7.5e-63	21	347

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040554	Polymorphism	p.ALA106THR	N/A
Swiss-Prot	VAR_040557	Polymorphism	p.ALA386THR	N/A
Swiss-Prot	VAR_040560	Polymorphism	p.ARG481CYS	N/A
Swiss-Prot	VAR_030578	Polymorphism	p.ARG302GLN	N/A
Swiss-Prot	VAR_040559	Polymorphism	p.GLY421SER	N/A
Swiss-Prot	VAR_040558	Polymorphism	p.SER406ARG	N/A
Swiss-Prot	VAR_040556	Polymorphism	p.THR381MET	N/A
Swiss-Prot	VAR_040555	Polymorphism	p.VAL171MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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