Results for the protein: Q8NER5

Results for the Protein: Q8NER5

74762565

130399

ACVR1C

NCBI, UniProt

ACV1C_HUMAN RecName: Full=Activin receptor type-1C; AltName: Full=Activin receptor type IC; Short=ACTR-IC; AltName: Full=Activin receptor-like kinase 7; Short=ALK-7; Flags: Precursor

			0 5 0 1 4

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: Q8NER5

Identical to: NP_660302

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_MAP4K4_6	cd06636	2.5e-05	178	471
PTKc_FGFR1	cd05098	0.00031	179	489
PTKc_FGFR2	cd05101	0.00054	180	490
STKc_PAK	cd06614	6.8e-09	180	456
STKc_CDK9	cd07865	0.00084	182	466
PTKc_FGFR	cd05053	2.2e-05	183	487
PTKc_Tie2	cd05088	0.00029	183	491
PTKc_FGFR4	cd05099	0.00034	183	493
STKc_myosinIIIA	cd06638	0.00034	183	467
PTKc_EGFR_like	cd05057	0.00012	184	488
PTK_Ryk	cd05043	0.00092	185	454
PTKc_Trk	cd05049	4.6e-07	186	488
STKc_MAP4K5	cd06646	4.2e-05	186	483
PTKc_TrkA	cd05092	0.00071	187	475
STKc_ASK	cd06624	0.00012	187	459
STKc_TNIK	cd06637	2.3e-06	188	460
STKc_CDK12	cd07864	7.3e-05	188	481
PTKc_ALK_LTK	cd05036	2.1e-06	189	484
PTKc_Ror	cd05048	1.7e-06	189	485
PTKc_FAK	cd05056	3.3e-06	189	490
PTKc_EphR_A2	cd05063	8.5e-05	189	486
PTKc_EphR	cd05033	8.7e-09	190	486
PTKc_Abl	cd05052	2.6e-06	190	486
PTKc_IGF-1R	cd05062	0.00052	190	484
PTKc_Lck_Blk	cd05067	1.1e-05	190	485
PTKc_Frk_like	cd05068	6.6e-12	190	485
PTKc_Yes	cd05069	8e-07	190	485
PTKc_Fyn_Yrk	cd05070	1.3e-05	190	485
PTKc_Lyn	cd05072	6.9e-06	190	485
PTKc_Hck	cd05073	9.2e-06	190	485
PTKc_Src	cd05071	6.7e-06	190	487
PTKc_Itk	cd05112	4.5e-05	190	483
STKc_CDK10	cd07845	6.7e-05	190	490
PTKc_InsR_like	cd05032	5.9e-07	191	484
PTKc_Src_like	cd05034	1.8e-09	191	485
PTKc_EphR_B	cd05065	2.3e-05	191	486
STKc_MAP4K3_like	cd06613	2.5e-07	191	448
PTKc_Jak_rpt2	cd05038	4.8e-06	192	486
PTKc_Csk_like	cd05039	5.2e-08	192	438
PTKc_EphR_A10	cd05064	0.00034	192	486
PTKc_EphR_A	cd05066	7.5e-05	192	486
PTKc_Jak1_rpt2	cd05079	0.00014	192	486
PTKc_Jak2_Jak3_rpt2	cd05081	2.5e-06	192	486
PTKc_Csk	cd05082	1.2e-07	192	485
PTK_HER3	cd05111	0.00087	192	488
PTKc_Btk_Bmx	cd05113	1.8e-06	192	483
PTKc_Tec_Rlk	cd05114	0.00046	192	483
STKc_MST4	cd06640	0.001	192	464
STKc_MST3	cd06641	0.00064	192	474
STKc_STK25-YSK1	cd06642	6.2e-05	192	464
STKc_CDKL1_4	cd07847	0.00025	192	484
STKc_Nek6_Nek7	cd08224	5.3e-05	192	459
STKc_Nek7	cd08229	2.6e-05	192	456
PTKc_Musk	cd05050	0.00025	193	484
PTKc_Tyk2_rpt2	cd05080	1.1e-06	193	487
PTKc_Chk	cd05083	1.2e-06	193	485
STKc_PDK1	cd05581	9.9e-05	193	466
PKc_MKK3_6	cd06617	0.00078	193	484
STKc_Nek3	cd08219	0.00042	193	460
PTKc_RET	cd05045	0.00028	194	489
STKc_Cdc7_like	cd06627	4.5e-08	194	444
STKc_MAPKKK_Byr2_lik	cd06628	7.4e-05	194	453
STKc_MAPKKK	cd06606	2.1e-12	194	466
STKc_CCRK	cd07832	2.1e-07	194	474
STKc_Nek4	cd08223	0.00095	194	453
PTKc_Axl_like	cd05035	0.00025	195	486
PTKc_Tec_like	cd05059	2.6e-05	196	483
PKc_STE	cd05122	7.9e-09	196	475
PKc_MAPKK_plant_like	cd06623	8.2e-06	196	483
STKc_Nek	cd08215	5.3e-06	196	451
STKc_FA2-like	cd08529	0.00045	196	428
PTKc_Srm_Brk	cd05148	3.7e-09	197	485
STKc_Yank1	cd05578	0.00048	197	419
STKc_myosinIII_like	cd06608	6.8e-06	197	449
STKc_OSR1_SPAK	cd06610	2.6e-05	197	481
STKc_MST1_2	cd06612	4.6e-08	197	444
STKc_MEKK3_like	cd06625	5.4e-06	197	453
STKc_MEKK4	cd06626	1.5e-06	197	444
STKc_CNK2-like	cd08530	0.00045	197	453
PTKc_Aatyk	cd05042	1.6e-05	198	484
PTKc_Syk_like	cd05060	2.3e-06	198	487
PTKc_Aatyk1_Aatyk3	cd05087	0.00074	198	484
PTKc_Aatyk2	cd05086	0.00063	198	484
PKc_MAPKK	cd06605	0.00027	198	450
STKc_CDK_like	cd07829	7.5e-05	198	478
PTKc	cd00192	5.2e-10	199	483
PTKc_Ack_like	cd05040	2.9e-06	199	418
PTKc_Fes_like	cd05041	1.1e-07	199	484
PTKc_Met_Ron	cd05058	0.00021	199	488
PTKc_c-ros	cd05044	0.00015	199	484
PTKc_Fes	cd05084	0.0003	199	484
PTKc_Fer	cd05085	2.6e-05	199	484
PTKc_Syk	cd05116	0.00041	199	466
STKc_CMGC	cd05118	4e-06	199	476
STKc_YSK4	cd06631	5e-05	199	454
STKc_MEKK1_plant	cd06632	2.1e-05	199	434
STKc_NAK1_like	cd06917	0.00064	199	490
STKc_CDKL2_3	cd07846	0.001	199	484
STKc_CdkB_plant	cd07837	1.1e-05	199	484
STKc_Nek9	cd08221	0.00018	200	456
PKc	cd00180	2.2e-49	201	482
PTKc_Zap-70	cd05115	0.00059	201	466
Activin_recp	pfam01064	8.4e-23	26	100
Pkinase	pfam00069	1.6e-52	195	482
TGF_beta_GS	pfam08515	1.8e-14	165	193
GS	smart00467	1.6e-13	165	195
Pkinase_Tyr	pfam07714	1.7e-14	195	482
TyrKc	smart00219	2.3e-12	195	482
STYKc	smart00221	3.5e-21	195	453
S_TKc	smart00220	2.5e-13	205	487

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041408	Polymorphism	p.GLY216ARG	N/A
Swiss-Prot	VAR_041407	Polymorphism	p.ILE195THR	N/A
Swiss-Prot	VAR_041410	Polymorphism	p.ILE355VAL	N/A
dbSNP	rs7594480	Polymorphism	p.ILE482VAL	N/A
Swiss-Prot	VAR_041409	Polymorphism	p.TRP267ARG	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258