Results for the protein: Q92772

Results for the Protein: Q92772

74762639

8999

CDKL2

NCBI, UniProt

CDKL2_HUMAN RecName: Full=Cyclin-dependent kinase-like 2; AltName: Full=Protein kinase p56 KKIAMRE; AltName: Full=Serine/threonine-protein kinase KKIAMRE

			0 6 0 1 5

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Swiss-Prot Protein: Q92772

Identical to: NP_003939

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_Csk_like	cd05039	2.1e-06	1	231
PTKc_Ror	cd05048	4.4e-08	1	235
PTKc_Abl	cd05052	4.1e-09	1	253
PTKc_PDGFR	cd05055	2.7e-06	1	240
PTKc_EGFR_like	cd05057	5.3e-06	1	244
PTKc_Tec_like	cd05059	2.6e-10	1	286
PTKc_InsR	cd05061	0.00022	1	258
PTKc_EphR_B	cd05065	1.6e-05	1	267
PTKc_EphR_A	cd05066	0.00012	1	267
PTKc_Frk_like	cd05068	1.3e-10	1	259
PTKc_Jak1_rpt2	cd05079	9.1e-09	1	290
PTKc_Tyk2_rpt2	cd05080	8e-08	1	284
PTKc_Csk	cd05082	2.3e-06	1	285
PTKc_Chk	cd05083	6.4e-06	1	266
PTKc_Tie2	cd05088	3.2e-06	1	311
PTKc_Tie1	cd05089	4.6e-05	1	314
PTKc_Ror1	cd05090	8.3e-05	1	253
PTKc_DDR2	cd05095	1.6e-05	1	258
PTKc_DDR1	cd05096	0.00076	1	265
PTKc_DDR_like	cd05097	2.1e-05	1	258
PTKc_FGFR1	cd05098	0.00052	1	275
PTK_HER3	cd05111	0.00011	1	244
STKc_ROCK	cd05596	0.00014	1	296
STKc_ROCK2	cd05621	0.00034	1	296
STKc_ROCK1	cd05622	0.00026	1	318
STKc_SLK_like	cd06611	7.2e-10	1	299
STKc_MAP4K3_like	cd06613	1.7e-15	1	286
PKc_MKK4	cd06616	2.2e-09	1	304
PKc_MKK3_6	cd06617	6.3e-10	1	301
PKc_MKK7	cd06618	2e-09	1	302
STKc_ASK	cd06624	7.5e-23	1	287
STKc_myosinIIIA	cd06638	8e-08	1	287
STKc_myosinIIIB	cd06639	1.4e-06	1	288
STKc_STK10_LOK	cd06644	3.9e-08	1	308
STKc_MAP4K3	cd06645	2.2e-09	1	286
STKc_MAP4K5	cd06646	2.7e-09	1	286
STKc_PAK_I	cd06647	3.9e-15	1	310
STKc_PAK2	cd06655	3.8e-09	1	316
STKc_PAK5	cd06658	1e-07	1	278
STKc_PAK6	cd06659	5.6e-10	1	310
STKc_PAK1	cd06654	1.6e-09	1	311
STKc_PAK3	cd06656	1.1e-09	1	313
STKc_PCTAIRE_like	cd07844	1.1e-72	1	287
STKc_CDK10	cd07845	1.7e-39	1	293
STKc_JNK	cd07850	8.9e-30	1	324
STKc_MAPK15	cd07852	1.4e-30	1	334
STKc_TEY_MAPK_plant	cd07858	1.3e-63	1	329
STKc_CDK9	cd07865	2.2e-51	1	287
STKc_CDK12	cd07864	2.8e-52	1	287
STKc_BUR1	cd07866	6.5e-32	1	287
STKc_CDC2L6	cd07867	3.9e-18	1	287
STKc_PFTAIRE1	cd07869	1.5e-45	1	302
STKc_PFTAIRE2	cd07870	2e-51	1	287
STKc_PCTAIRE3	cd07871	8.5e-50	1	287
STKc_PCTAIRE2	cd07872	2.7e-44	1	303
STKc_PCTAIRE1	cd07873	3.4e-48	1	301
STKc_JNK3	cd07874	2.6e-22	1	344
STKc_JNK1	cd07875	4.5e-12	1	328
STKc_JNK2	cd07876	1.5e-18	1	326
STKc_p38gamma_MAPK12	cd07880	1.2e-34	1	329
STKc_CDK8	cd07868	1.3e-15	1	287
STKc_Nek6_Nek7	cd08224	5.6e-10	1	291
STKc_Nek6	cd08228	6.4e-08	1	291
STKc_Nek7	cd08229	3.7e-09	1	284
PTKc_Jak_rpt2	cd05038	2.1e-09	2	290
PTKc_Musk	cd05050	1.1e-06	2	246
PTKc_FGFR	cd05053	5.4e-07	2	268
PTKc_FAK	cd05056	5.6e-08	2	248
PTKc_EphR_A2	cd05063	8.7e-05	2	267
PTKc_FGFR4	cd05099	7.7e-07	2	273
PTKc_EGFR	cd05108	1.4e-05	2	339
PTKc_HER2	cd05109	8.8e-05	2	301
PTKc_HER4	cd05110	0.00014	2	325
PTKc_Itk	cd05112	1.3e-08	2	264
PTKc_Tec_Rlk	cd05114	1.2e-07	2	264
PTKc_Srm_Brk	cd05148	1.6e-09	2	287
STKc_ROCK_NDR_like	cd05573	1.4e-10	2	362
STKc_phototropin_lik	cd05574	2.4e-07	2	253
STKc_PKA	cd05580	9.8e-13	2	314
STKc_PDK1	cd05581	4.7e-18	2	287
STKc_DMPK_like	cd05597	2.6e-07	2	344
STKc_LATS	cd05598	7.8e-05	2	354
STKc_NDR_like	cd05599	5.1e-07	2	268
STKc_CRIK	cd05601	4.5e-08	2	289
STKc_MAST	cd05609	1.4e-08	2	312
STKc_PRKX_like	cd05612	5.9e-10	2	293
STKc_MRCK_alpha	cd05623	5e-07	2	296
STKc_MRCK_beta	cd05624	4.5e-06	2	295
STKc_NDR2	cd05627	2e-05	2	339
STKc_NDR1	cd05628	2.1e-06	2	319
STKc_NDR_like_fungal	cd05629	0.00037	2	336
STKc_Sid2p_Dbf2p	cd05600	1.5e-08	2	335
PKc_MAPKK	cd06605	9.9e-15	2	291
STKc_TAO	cd06607	2.7e-09	2	328
STKc_myosinIII_like	cd06608	7.7e-12	2	287
STKc_MST3_like	cd06609	1.2e-13	2	313
STKc_OSR1_SPAK	cd06610	6e-14	2	287
STKc_MST1_2	cd06612	7.3e-17	2	287
STKc_PAK	cd06614	7.6e-21	2	300
PKc_MEK	cd06615	1.4e-11	2	300
PKc_MKK5	cd06619	2.6e-12	2	308
PKc_MAPKK_PBS2_like	cd06622	1.9e-10	2	324
STKc_TAO3	cd06633	5.2e-07	2	328
STKc_TAO2	cd06634	9.4e-10	2	333
STKc_TAO1	cd06635	3.6e-08	2	328
STKc_MST4	cd06640	2e-08	2	308
STKc_MST3	cd06641	1.1e-08	2	308
STKc_STK25-YSK1	cd06642	1.5e-09	2	308
STKc_SLK	cd06643	2.6e-08	2	306
STKc_PAK_II	cd06648	8.5e-12	2	300
PKc_MEK2	cd06649	6.1e-07	2	309
PKc_MEK1	cd06650	1.5e-06	2	314
PKc_MAPKK_Pek1_like	cd06621	1.7e-11	2	301
STKc_MEKK3_like_1	cd06653	1.4e-10	2	259
STKc_PAK4	cd06657	1.3e-07	2	280
STKc_NAK1_like	cd06917	2.6e-12	2	305
STKc_CDKL	cd07833	9.6e-223	2	287
STKc_CdkB_plant	cd07837	1.1e-67	2	288
STKc_CDC2L1	cd07843	2.4e-46	2	287
STKc_CDKL2_3	cd07846	1.3e-252	2	287
STKc_CDKL1_4	cd07847	2.5e-147	2	287
STKc_CDKL5	cd07848	2.7e-100	2	287
STKc_ERK1_2_like	cd07849	1.4e-39	2	326
STKc_p38	cd07851	1.7e-30	2	322
STKc_ERK5	cd07855	3.2e-22	2	323
STKc_Sty1_Hog1	cd07856	2.1e-43	2	316
STKc_CDK6	cd07862	2.5e-48	2	287
STKc_p38alpha_MAPK14	cd07877	6.9e-29	2	315
STKc_p38beta_MAPK11	cd07878	2.7e-26	2	327
STKc_p38delta_MAPK13	cd07879	2.6e-38	2	329
PK_STRAD	cd08216	2.9e-08	2	304
PK_STRAD_beta	cd08226	4.8e-05	2	306
SPS1	COG0515	1.3e-65	2	473
PTKc_InsR_like	cd05032	5.4e-07	3	265
PTKc_Trk	cd05049	2.2e-08	3	251
PTKc_Fyn_Yrk	cd05070	2.3e-05	3	259
PTKc_Lyn	cd05072	9.4e-07	3	263
PTKc_TrkA	cd05092	1.3e-05	3	270
PTKc_TrkB	cd05093	1.8e-05	3	262
PTKc_TrkC	cd05094	0.00089	3	299
PTKc_FGFR3	cd05100	0.00061	3	285
PTKc_FGFR2	cd05101	8.4e-05	3	248
PTKc_VEGFR2	cd05103	0.00017	3	290
PTKc_VEGFR3	cd05102	0.00026	3	267
PTKc_Btk_Bmx	cd05113	4e-09	3	286
PKc_STE	cd05122	1.7e-28	3	286
STKc_Yank1	cd05578	1.3e-13	3	287
STKc_MSK_N	cd05583	1.6e-08	3	306
STKc_cPKC	cd05587	2.3e-08	3	355
STKc_GRK4_like	cd05605	1.4e-09	3	290
STKc_MSK1_N	cd05613	1.9e-06	3	306
STKc_MSK2_N	cd05614	1.3e-06	3	295
STKc_cPKC_beta	cd05616	1.9e-06	3	323
STKc_cPKC_alpha	cd05615	4.9e-08	3	315
STKc_GRK6	cd05630	8.7e-06	3	290
STKc_GRK4	cd05631	1.6e-06	3	281
STKc_GRK5	cd05632	1.3e-06	3	281
STKc_MAPKKK	cd06606	2.5e-53	3	287
PKc_MAPKK_Byr1_like	cd06620	2.2e-10	3	293
STKc_MEKK4	cd06626	4e-19	3	287
STKc_Cdc7_like	cd06627	1.9e-19	3	287
STKc_MAPKKK_Byr2_lik	cd06628	7.9e-25	3	287
STKc_YSK4	cd06631	1.2e-14	3	287
STKc_MEKK3	cd06651	2.7e-12	3	289
STKc_MEKK1	cd06630	2.2e-12	3	288
STKc_CCRK	cd07832	1.7e-72	3	288
STKc_MAPK	cd07834	1.5e-54	3	341
STKc_Pho85	cd07836	1.9e-72	3	287
STKc_CDK5	cd07839	3.7e-70	3	287
STKc_CDK7	cd07841	2.1e-54	3	303
STKc_CDK8_like	cd07842	3.1e-36	3	287
STKc_MAPK4_6	cd07854	3e-16	3	317
STKc_MPK1	cd07857	2e-25	3	316
STKc_TDY_MAPK_plant	cd07859	5.8e-50	3	334
STKc_CDK2_3	cd07860	9.9e-81	3	287
STKc_CDK1_euk	cd07861	4.7e-81	3	287
STKc_CDK4	cd07863	1.3e-48	3	287
STKc_NLK	cd07853	7.6e-19	3	354
STKc_Nek	cd08215	2.2e-20	3	287
STKc_Nek2	cd08217	5.2e-16	3	287
STKc_Nek1	cd08218	1.1e-15	3	268
STKc_Nek3	cd08219	3.3e-12	3	249
STKc_Nek8	cd08220	4.1e-09	3	287
STKc_Nek9	cd08221	2.2e-11	3	287
STKc_Nek11	cd08222	4.7e-06	3	248
STKc_Nek4	cd08223	3e-09	3	259
STKc_Nek5	cd08225	1.4e-09	3	287
STKc_Nek10	cd08528	7e-08	3	280
STKc_FA2-like	cd08529	1.6e-11	3	287
STKc_CNK2-like	cd08530	3.1e-09	3	287
PTK_CCK4	cd05046	0.00018	4	265
PTKc_Jak2_Jak3_rpt2	cd05081	8.1e-10	4	288
STKc_CMGC	cd05118	3.1e-130	4	287
STKc_PKN	cd05589	6.5e-09	4	327
STKc_MAP4K4_6	cd06636	1.4e-06	4	287
STKc_TNIK	cd06637	2e-08	4	287
STKc_CDK_like	cd07829	7.8e-94	4	287
STKc_MAK_like	cd07830	2.3e-69	4	287
STKc_MOK	cd07831	1.1e-36	4	287
STKc_CDK1_like	cd07835	5e-81	4	287
STKc_CDK4_6_like	cd07838	8.4e-31	4	287
STKc_CDK9_like	cd07840	2e-63	4	287
PTKc_Src_like	cd05034	1.1e-09	5	286
PTKc_ALK_LTK	cd05036	1e-05	5	245
PTKc_DDR	cd05051	1.7e-05	5	289
PTKc_Lck_Blk	cd05067	4.4e-07	5	286
PTKc_Yes	cd05069	2.2e-06	5	253
PTKc_Src	cd05071	1.6e-05	5	261
PTKc_Hck	cd05073	1.8e-07	5	263
PKc_MAPKK_plant_like	cd06623	1.2e-19	5	291
PK_STRAD_alpha	cd08227	0.00026	5	303
PTKc_Axl_like	cd05035	0.00024	6	260
PTK_Ryk	cd05043	0.0006	6	228
PTKc_RET	cd05045	0.00022	6	293
PTKc_Tyro3	cd05074	0.00037	6	260
PTKc_Ror2	cd05091	0.00067	6	243
STKc_MEKK3_like	cd06625	3e-23	6	287
STKc_MEKK2	cd06652	6.9e-09	6	288
STKc_RSK_N	cd05582	5.1e-06	7	331
STKc_p70S6K	cd05584	5.5e-08	7	346
STKc_Rim15_like	cd05611	6.3e-06	7	290
PTKc	cd00192	7.6e-13	8	287
PTKc_Ack_like	cd05040	2.1e-10	8	242
PTKc_Fes_like	cd05041	1.1e-10	8	287
PTKc_c-ros	cd05044	1.5e-06	8	258
PTKc_Tie	cd05047	1e-05	8	294
PTKc_Met_Ron	cd05058	0.00024	8	269
PTKc_Syk_like	cd05060	6.1e-07	8	292
PTKc_Fes	cd05084	1.6e-07	8	288
PTKc_Fer	cd05085	1.4e-08	8	265
PTKc_Syk	cd05116	2.8e-07	8	255
STKc_PKC	cd05570	7.4e-12	8	280
STKc_PKB	cd05571	2.4e-10	8	333
STKc_aPKC	cd05588	1.9e-09	8	328
STKc_nPKC_eta	cd05590	1.4e-07	8	315
STKc_nPKC_epsilon	cd05591	6.6e-09	8	355
STKc_nPKC_theta_delt	cd05592	2.2e-08	8	316
STKc_PKB_gamma	cd05593	4.8e-07	8	349
STKc_PKB_beta	cd05595	1.1e-06	8	331
STKc_PKB_alpha	cd05594	2.4e-07	8	322
STKc_SGK1	cd05602	1.9e-05	8	333
STKc_SGK2	cd05603	2.7e-08	8	320
STKc_SGK3	cd05604	1.8e-05	8	338
STKc_aPKC_zeta	cd05617	9.4e-09	8	326
STKc_aPKC_iota	cd05618	2.1e-07	8	328
STKc_nPKC_delta	cd05620	8e-05	8	322
STKc_nPKC_theta	cd05619	7.5e-09	8	320
STKc_SGK	cd05575	3.4e-07	8	344
STKc_beta_ARK	cd05606	6.9e-06	9	280
STKc_GRK3	cd05633	0.0003	9	309
STKc_MAPKKK_Bck1_lik	cd06629	6e-15	9	287
STKc_MEKK1_plant	cd06632	4e-17	9	287
PKc	cd00180	1e-73	10	285
PTKc_Aatyk	cd05042	0.0002	10	284
PTKc_Aatyk1_Aatyk3	cd05087	0.00047	10	265
PTKc_Zap-70	cd05115	1.1e-06	10	255
STKc_AGC	cd05123	3.2e-17	10	287
STKc_cGK_PKG	cd05572	5.8e-12	10	242
STKc_GRK	cd05577	9.2e-09	10	305
STKc_YPK1_like	cd05585	9.6e-10	10	313
STKc_Sck1_like	cd05586	3.1e-09	10	366
STKc_MAST_like	cd05579	1.2e-15	10	291
STKc_GRK7	cd05607	3.9e-08	10	280
STKc_GRK1	cd05608	2.5e-09	10	307
Pkinase	pfam00069	3.2e-98	4	287
Pkinase_Tyr	pfam07714	1.7e-17	4	286
TyrKc	smart00219	1.5e-16	4	286
STYKc	smart00221	1.2e-87	4	287
S_TKc	smart00220	1.4e-100	14	287

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041990	Polymorphism	p.ALA411VAL	N/A
Swiss-Prot	VAR_041988	Polymorphism	p.ARG149GLN	N/A
Swiss-Prot	VAR_053929	Polymorphism	p.ILE132THR	N/A
Swiss-Prot	VAR_041987	Polymorphism	p.LEU98ILE	N/A
Swiss-Prot	VAR_041989	Polymorphism	p.MET197THR	N/A
dbSNP	rs35921414	Polymorphism	p.TYR77SER	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258