Results for the protein: Q9H2G2

Results for the Protein: Q9H2G2

74762732

9748

SLK

NCBI, UniProt

SLK_HUMAN RecName: Full=STE20-like serine/threonine-protein kinase; Short=STE20-like kinase; Short=hSLK; AltName: Full=CTCL tumor antigen se20-9; AltName: Full=STE20-related serine/threonine-protein kinase; Short=STE20-related kinase; AltName: Full=Serine/threonine-protein kinase 2

			0 8 0 0 8

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Swiss-Prot Protein: Q9H2G2

Identical to: NP_055535

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK1	cd05622	8.1e-08	1	341
STKc_ROCK	cd05596	5.9e-08	1	340
STKc_TAO1	cd06635	1.8e-50	7	326
STKc_MAPK4_6	cd07854	2.2e-06	10	326
STKc_TAO3	cd06633	1.8e-51	11	326
STKc_PAK5	cd06658	8.1e-44	11	308
STKc_myosinIIIA	cd06638	2.2e-80	12	292
STKc_myosinIIIB	cd06639	3.2e-73	12	293
STKc_PAK6	cd06659	1.9e-51	12	314
STKc_PAK1	cd06654	1.2e-57	13	314
STKc_PAK4	cd06657	3.8e-42	13	310
STKc_PAK	cd06614	1.5e-88	14	304
STKc_PAK_I	cd06647	2.4e-68	14	312
STKc_PAK2	cd06655	2.3e-57	14	315
STKc_PAK3	cd06656	3.2e-60	14	316
STKc_PAK_II	cd06648	6.2e-53	14	304
STKc_JNK2	cd07876	4.1e-05	14	328
PTKc_PDGFR	cd05055	0.00012	15	294
STKc_TAO2	cd06634	2.3e-47	17	325
STKc_TAO	cd06607	4e-67	18	326
PKc_MKK7	cd06618	1e-22	20	306
STKc_p38	cd07851	7.6e-11	20	349
STKc_JNK	cd07850	4.1e-07	20	326
STKc_p38gamma_MAPK12	cd07880	9.6e-08	20	350
PTKc_FAK	cd05056	1.3e-09	21	298
STKc_MAP4K4_6	cd06636	1.3e-69	21	292
STKc_STK10_LOK	cd06644	1.9e-216	21	311
STKc_JNK1	cd07875	0.00037	21	405
STKc_p38alpha_MAPK14	cd07877	4.7e-07	21	349
PTKc_DDR	cd05051	2.4e-05	22	271
PTK_Jak1_rpt1	cd05077	2.2e-05	22	291
PTKc_Trk	cd05049	1.1e-11	23	289
PTKc_Tie2	cd05088	1.3e-06	23	311
PTKc_TrkA	cd05092	3.9e-07	23	293
PTKc_TrkB	cd05093	1.8e-07	23	295
PTKc_TrkC	cd05094	3e-05	23	352
PTKc_FGFR1	cd05098	1.7e-07	23	299
PKc_MKK4	cd06616	1.9e-17	23	312
STKc_MAP4K5	cd06646	9.5e-79	23	291
STKc_p38beta_MAPK11	cd07878	5e-06	23	335
STKc_p38delta_MAPK13	cd07879	6.2e-05	23	332
STKc_CDK12	cd07864	3e-12	23	292
STKc_ASK	cd06624	1.2e-43	24	292
PTKc_EGFR_like	cd05057	1.4e-08	25	306
PTKc_Ror2	cd05091	0.00063	25	284
PTKc_VEGFR2	cd05103	0.00023	25	297
PTKc_HER2	cd05109	1.4e-06	25	306
PTK_HER3	cd05111	2.4e-08	25	306
PTKc_FGFR2	cd05101	7.8e-08	25	299
PTKc_EGFR	cd05108	3.8e-07	26	332
PTKc_HER4	cd05110	8.7e-06	26	322
STKc_CDK10	cd07845	5.4e-12	26	299
STKc_BUR1	cd07866	8.1e-13	26	292
PTK_CCK4	cd05046	9.2e-08	27	292
PTKc_EphR_A2	cd05063	8.3e-06	27	291
PTKc_EphR_A10	cd05064	1.6e-06	27	294
PTKc_EphR_B	cd05065	2.3e-07	27	294
PTKc_Csk	cd05082	1.5e-06	27	290
PTKc_Chk	cd05083	7.2e-06	27	290
PKc_MAPKK_Byr1_like	cd06620	5e-18	27	307
STKc_TNIK	cd06637	6.4e-72	27	292
STKc_MAP4K3	cd06645	8.5e-82	27	291
PKc_MEK2	cd06649	3.6e-10	27	313
PKc_MEK1	cd06650	2.6e-09	27	316
STKc_MAPK15	cd07852	1.1e-11	27	322
STKc_PCTAIRE2	cd07872	9e-07	27	337
STKc_PCTAIRE1	cd07873	1.2e-06	27	317
PTKc_EphR	cd05033	4.8e-08	28	292
PTKc_FGFR	cd05053	1.4e-10	28	293
PTKc_Tec_like	cd05059	1.3e-09	28	293
PTKc_EphR_A	cd05066	3.7e-06	28	294
PTKc_FGFR4	cd05099	1.4e-08	28	306
PTKc_FGFR3	cd05100	4.4e-06	28	330
PTKc_Itk	cd05112	2e-09	28	291
PTKc_Btk_Bmx	cd05113	8e-14	28	291
PTKc_Tec_Rlk	cd05114	6.5e-10	28	291
STKc_myosinIII_like	cd06608	1.6e-103	28	292
STKc_SLK_like	cd06611	2.8e-235	28	306
STKc_SLK	cd06643	1.7e-258	28	309
STKc_PCTAIRE_like	cd07844	1e-12	28	327
STKc_ERK1_2_like	cd07849	2.7e-08	28	337
STKc_PFTAIRE1	cd07869	1.8e-05	28	305
STKc_PCTAIRE3	cd07871	3.6e-08	28	311
STKc_PFTAIRE2	cd07870	1.8e-08	28	292
PTKc_Jak_rpt2	cd05038	2.6e-11	29	295
STKc_MST3	cd06641	2.5e-70	29	311
STKc_MST4	cd06640	8.7e-71	29	311
STKc_STK25-YSK1	cd06642	3.3e-73	29	311
STKc_CDK9	cd07865	1.1e-11	29	292
PTKc_InsR_like	cd05032	7.2e-10	30	289
PTKc_ALK_LTK	cd05036	5.1e-10	30	293
PTKc_Ror	cd05048	9.3e-09	30	255
PTKc_Musk	cd05050	1.4e-10	30	289
PTKc_InsR	cd05061	1.8e-07	30	305
PTKc_Lck_Blk	cd05067	3.6e-05	30	291
PTKc_Fyn_Yrk	cd05070	7.7e-06	30	294
PTKc_Lyn	cd05072	6.8e-06	30	291
PTKc_Ror1	cd05090	3.3e-06	30	284
PTKc_DDR2	cd05095	3.7e-06	30	288
PTKc_DDR1	cd05096	0.00086	30	294
PTKc_DDR_like	cd05097	3.6e-05	30	294
STKc_MST1_2	cd06612	8.5e-121	30	292
STKc_MAP4K3_like	cd06613	8e-125	30	291
STKc_MEKK3_like_1	cd06653	8.2e-31	30	292
STKc_TEY_MAPK_plant	cd07858	1e-07	30	362
PTKc_Jak2_Jak3_rpt2	cd05081	1.6e-08	31	298
PTKc_Jak1_rpt2	cd05079	9.8e-07	31	294
STKc_ROCK_NDR_like	cd05573	6.7e-15	31	364
STKc_phototropin_lik	cd05574	7.6e-12	31	311
STKc_PKA	cd05580	1.3e-14	31	333
STKc_PDK1	cd05581	7.2e-21	31	292
STKc_DMPK_like	cd05597	3.9e-09	31	361
STKc_Sid2p_Dbf2p	cd05600	2.3e-08	31	354
STKc_NDR_like	cd05599	2.8e-09	31	350
STKc_CRIK	cd05601	2.7e-11	31	346
STKc_MRCK_alpha	cd05623	5.4e-10	31	354
STKc_MRCK_beta	cd05624	1.9e-08	31	351
STKc_NDR2	cd05627	4.5e-08	31	368
STKc_NDR1	cd05628	1.6e-09	31	368
STKc_NDR_like_fungal	cd05629	3.9e-07	31	368
STKc_MAST	cd05609	2.2e-10	31	357
PKc_MAPKK	cd06605	3.9e-45	31	296
PKc_MEK	cd06615	1.1e-17	31	304
PKc_MAPKK_plant_like	cd06623	1.6e-59	31	297
STKc_ERK5	cd07855	4.7e-08	31	330
STKc_JNK3	cd07874	4.5e-05	31	407
STKc_Nek6	cd08228	1.5e-21	31	294
SPS1	COG0515	9.3e-65	31	494
STKc_MSK_N	cd05583	8.6e-12	32	311
STKc_cPKC	cd05587	1.2e-11	32	355
STKc_LATS	cd05598	1.5e-09	32	372
STKc_PRKX_like	cd05612	1.7e-10	32	324
STKc_cPKC_alpha	cd05615	9.9e-08	32	360
STKc_cPKC_beta	cd05616	1.6e-07	32	355
STKc_LATS2	cd05626	6.3e-07	32	364
STKc_LATS1	cd05625	5.7e-06	32	372
STKc_OSR1_SPAK	cd06610	7e-68	32	292
STKc_MST3_like	cd06609	3.9e-96	32	311
PKc_MKK3_6	cd06617	1.6e-19	32	309
PKc_MKK5	cd06619	5.1e-28	32	316
PKc_MAPKK_Pek1_like	cd06621	4.3e-24	32	304
PKc_MAPKK_PBS2_like	cd06622	3.3e-32	32	356
STKc_CDKL	cd07833	2.5e-15	32	292
STKc_CdkB_plant	cd07837	6.7e-13	32	293
STKc_CDC2L1	cd07843	2.6e-13	32	292
STKc_CDKL2_3	cd07846	1.1e-12	32	292
STKc_CDKL1_4	cd07847	9.5e-21	32	292
STKc_CDKL5	cd07848	8.9e-07	32	292
STKc_CDK6	cd07862	8.8e-07	32	292
PK_STRAD	cd08216	7.2e-11	32	306
STKc_Nek6_Nek7	cd08224	9.8e-26	32	298
PK_STRAD_alpha	cd08227	4.1e-07	32	382
STKc_FA2-like	cd08529	1.5e-25	32	292
STKc_CNK2-like	cd08530	5.5e-25	32	292
PTKc_Tyk2_rpt2	cd05080	2.4e-08	33	296
PKc_STE	cd05122	6.8e-143	33	291
STKc_GRK4_like	cd05605	2.3e-08	33	323
STKc_GRK6	cd05630	3.1e-05	33	313
STKc_GRK4	cd05631	2.1e-05	33	318
STKc_GRK5	cd05632	5.6e-06	33	318
STKc_MAPKKK	cd06606	1.6e-78	33	292
STKc_MAPKKK_Byr2_lik	cd06628	2.4e-49	33	292
STKc_MAPKKK_Bck1_lik	cd06629	7.8e-21	33	292
STKc_MEKK1	cd06630	1e-27	33	293
STKc_YSK4	cd06631	1.5e-28	33	292
STKc_CCRK	cd07832	1.7e-15	33	293
STKc_MAPK	cd07834	1.8e-12	33	330
STKc_CDK7	cd07841	1.7e-14	33	299
STKc_CDK8_like	cd07842	1.1e-10	33	292
STKc_CDK2_3	cd07860	6e-19	33	311
STKc_CDC2L6	cd07867	9.8e-07	33	311
STKc_CDK8	cd07868	2.9e-06	33	314
STKc_MPK1	cd07857	3.6e-10	33	315
STKc_NLK	cd07853	5.1e-06	33	422
STKc_Nek2	cd08217	3.1e-19	33	292
STKc_Nek9	cd08221	4.5e-21	33	292
STKc_Nek	cd08215	8.8e-58	33	292
STKc_Nek10	cd08528	5.6e-17	33	289
PTKc_Src_like	cd05034	5.2e-09	34	268
PTKc_Csk_like	cd05039	4.5e-07	34	265
PTKc_Abl	cd05052	6.7e-09	34	291
PTKc_Frk_like	cd05068	2.7e-10	34	291
PTKc_Src	cd05071	7.8e-06	34	292
PTKc_Hck	cd05073	1.5e-06	34	291
PTKc_Tyro3	cd05074	1.3e-05	34	294
PTKc_Yes	cd05069	5e-07	34	289
PTKc_Tie1	cd05089	1.6e-06	34	310
STKc_CMGC	cd05118	3.7e-19	34	292
PTKc_IGF-1R	cd05062	4.6e-07	34	292
PTKc_Srm_Brk	cd05148	1.5e-09	34	276
STKc_Yank1	cd05578	3.1e-15	34	292
STKc_PKN	cd05589	3.4e-11	34	359
STKc_MSK1_N	cd05613	1.7e-08	34	309
STKc_MSK2_N	cd05614	3.5e-10	34	348
STKc_MEKK3_like	cd06625	2.7e-52	34	292
STKc_MEKK4	cd06626	1.2e-32	34	292
STKc_MEKK3	cd06651	5.4e-32	34	294
STKc_MEKK2	cd06652	7.7e-22	34	293
STKc_NAK1_like	cd06917	5.6e-51	34	308
STKc_CDK_like	cd07829	8.2e-20	34	292
STKc_MOK	cd07831	2.1e-12	34	292
STKc_MAK_like	cd07830	2.2e-17	34	292
STKc_CDK1_like	cd07835	7.1e-14	34	311
STKc_Pho85	cd07836	8.6e-19	34	292
STKc_CDK5	cd07839	1.3e-11	34	292
STKc_CDK9_like	cd07840	2.1e-17	34	292
STKc_TDY_MAPK_plant	cd07859	1.6e-06	34	385
STKc_CDK1_euk	cd07861	5.4e-17	34	316
STKc_CDK4	cd07863	9.5e-09	34	292
STKc_CDK4_6_like	cd07838	2.6e-13	34	292
STKc_Nek1	cd08218	6.1e-35	34	292
STKc_Nek3	cd08219	1.5e-25	34	292
STKc_Nek8	cd08220	2.6e-21	34	292
STKc_Nek4	cd08223	4.8e-21	34	292
STKc_Nek7	cd08229	1.9e-12	34	290
STKc_Nek5	cd08225	8.8e-33	34	292
STKc_Nek11	cd08222	1.5e-34	34	292
PTKc_Tie	cd05047	4.2e-06	35	295
PTKc_Met_Ron	cd05058	1.2e-06	35	296
PK_STRAD_beta	cd08226	7.5e-06	35	365
PTKc_Axl_like	cd05035	7.7e-07	36	294
PTK_Ryk	cd05043	5.1e-05	36	269
PTKc_RET	cd05045	1.1e-06	36	294
PTKc_Axl	cd05075	6e-05	36	294
STKc_Cdc7_like	cd06627	6.8e-71	36	292
STKc_Sty1_Hog1	cd07856	9.6e-07	36	325
STKc_RSK_N	cd05582	5.8e-20	37	349
STKc_Rim15_like	cd05611	1.2e-05	37	351
STKc_p70S6K	cd05584	1.8e-12	37	347
PTKc	cd00192	9.2e-18	38	291
PTK_Jak_rpt1	cd05037	0.00013	38	291
PTKc_Fes_like	cd05041	1.4e-10	38	292
PTKc_Aatyk	cd05042	3.9e-07	38	289
PTKc_Syk_like	cd05060	1.8e-09	38	295
PTKc_Ack_like	cd05040	9e-14	38	293
PTK_Jak2_Jak3_rpt1	cd05078	1.9e-07	38	291
PTKc_Fes	cd05084	4.5e-08	38	292
PTKc_Aatyk2	cd05086	1.4e-06	38	294
PTKc_Aatyk1_Aatyk3	cd05087	0.00028	38	291
PTKc_Syk	cd05116	2e-07	38	292
STKc_MEKK1_plant	cd06632	2.1e-52	38	292
PTKc_Zap-70	cd05115	4.8e-08	39	305
PKc	cd00180	1.7e-81	40	290
PTKc_c-ros	cd05044	9.2e-07	40	289
PTKc_Fer	cd05085	1.3e-08	40	292
STKc_AGC	cd05123	2.4e-30	40	292
STKc_PKC	cd05570	2.4e-14	40	333
STKc_PKB	cd05571	1.2e-16	40	363
STKc_cGK_PKG	cd05572	4.7e-16	40	298
STKc_SGK	cd05575	5.5e-10	40	360
STKc_GRK	cd05577	2.3e-10	40	306
STKc_MAST_like	cd05579	1.2e-18	40	296
STKc_YPK1_like	cd05585	1.3e-14	40	355
STKc_Sck1_like	cd05586	7.1e-10	40	399
STKc_aPKC	cd05588	2e-10	40	355
STKc_nPKC_eta	cd05590	2.6e-14	40	357
STKc_nPKC_epsilon	cd05591	1.2e-12	40	347
STKc_nPKC_theta_delt	cd05592	8.3e-15	40	362
STKc_PKB_gamma	cd05593	1.5e-09	40	361
STKc_PKB_alpha	cd05594	8.8e-11	40	362
STKc_PKB_beta	cd05595	1.6e-09	40	361
STKc_SGK1	cd05602	2.7e-08	40	366
STKc_SGK2	cd05603	2.5e-10	40	361
STKc_SGK3	cd05604	2.7e-07	40	374
STKc_beta_ARK	cd05606	3.9e-07	40	306
STKc_GRK7	cd05607	1.8e-07	40	311
STKc_GRK1	cd05608	4.1e-14	40	317
STKc_nPKC_delta	cd05620	4.7e-06	40	358
STKc_aPKC_zeta	cd05617	1.2e-08	40	371
STKc_aPKC_iota	cd05618	5.2e-07	40	355
STKc_nPKC_theta	cd05619	4.9e-11	40	362
STKc_GRK3	cd05633	4e-06	40	307
Pkinase	pfam00069	2.1e-91	34	292
Pkinase_Tyr	pfam07714	1.2e-26	34	292
TyrKc	smart00219	2.2e-16	34	290
STYKc	smart00221	2.6e-88	34	292
S_TKc	smart00220	5.5e-99	44	292
KIND	smart00750	9.6e-37	114	300
PKK	pfam12474	8.8e-43	851	990
PKK	pfam12474	2.1e-63	1019	1160

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041083	Polymorphism	p.ALA658GLY	N/A
Swiss-Prot	VAR_041081	Polymorphism	p.CYS552TYR	N/A
Swiss-Prot	VAR_041080	Polymorphism	p.GLN405LYS	N/A
Swiss-Prot	VAR_041082	Polymorphism	p.GLU604GLN	N/A
Swiss-Prot	VAR_051666	Polymorphism	p.GLY666GLU	N/A
Swiss-Prot	VAR_041084	Polymorphism	p.ILE679THR	N/A
Swiss-Prot	VAR_041085	Polymorphism	p.LYS683ASN	N/A
Swiss-Prot	VAR_041086	Polymorphism	p.THR697ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258