Results for the protein: P54753

Results for the Protein: P54753

76803655

2049

EPHB3

NCBI, UniProt

EPHB3_HUMAN RecName: Full=Ephrin type-B receptor 3; AltName: Full=EPH-like tyrosine kinase 2; Short=EPH-like kinase 2; AltName: Full=Embryonic kinase 2; Short=EK2; Short=hEK2; AltName: Full=Tyrosine-protein kinase TYRO6; Flags: Precursor

			0 5 0 0 5

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Swiss-Prot Protein: P54753

Identical to: NP_004434

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
FN3	cd00063	3.6e-14	340	448
FN3	cd00063	1.6e-20	453	542
PTKc_Kit	cd05104	1e-12	519	896
PTKc_PDGFR_beta	cd05107	4.7e-09	521	897
PTKc_VEGFR	cd05054	1.2e-17	539	899
PTKc_CSF-1R	cd05106	6.4e-14	584	897
STKc_PAK5	cd06658	4.1e-05	587	921
STKc_PAK4	cd06657	9.3e-05	589	913
PTKc_PDGFR_alpha	cd05105	2e-12	592	898
PTKc_PDGFR	cd05055	7.8e-16	593	896
STKc_TAO1	cd06635	0.00049	611	945
STKc_myosinIIIA	cd06638	8.4e-05	612	896
STKc_myosinIIIB	cd06639	4.5e-05	612	897
STKc_PAK6	cd06659	1.3e-07	612	927
STKc_p38	cd07851	1.6e-05	612	948
PTKc_FGFR1	cd05098	1.3e-30	613	903
PTKc_FGFR2	cd05101	1.1e-37	613	903
STKc_TAO3	cd06633	0.00078	613	918
PTKc_EGFR_like	cd05057	6.1e-68	614	906
STKc_PAK	cd06614	1.6e-11	614	909
STKc_PAK_II	cd06648	1.2e-08	614	909
STKc_JNK	cd07850	0.00021	615	983
STKc_TAO	cd06607	0.00015	616	907
STKc_TAO2	cd06634	2e-05	616	914
PTKc_FGFR4	cd05099	5.4e-40	617	916
PTKc_FGFR3	cd05100	1.3e-25	617	941
STKc_p38alpha_MAPK14	cd07877	0.00049	617	948
PTK_Tyk2_rpt1	cd05076	1.5e-06	618	893
PKc_MKK7	cd06618	8.6e-09	620	907
STKc_CDK9	cd07865	1.9e-06	620	917
PTKc_HER2	cd05109	4.8e-52	622	906
STKc_ASK	cd06624	2.3e-09	622	896
PTKc_HER4	cd05110	7.7e-45	623	921
STKc_MAP4K4_6	cd06636	0.00012	623	888
STKc_MAP4K3	cd06645	0.00016	623	900
STKc_MAP4K5	cd06646	0.001	623	893
STKc_PCTAIRE2	cd07872	0.00046	623	943
STKc_ERK5	cd07855	0.00012	624	949
STKc_PCTAIRE3	cd07871	4.6e-05	624	917
STKc_p38gamma_MAPK12	cd07880	3.3e-05	624	970
PTKc_VEGFR3	cd05102	2.4e-16	625	899
PTKc_VEGFR2	cd05103	6.8e-14	625	899
PTKc_EGFR	cd05108	2.5e-47	625	945
PTK_HER3	cd05111	1.1e-46	625	906
PTKc_ALK_LTK	cd05036	2.6e-58	626	894
PTKc_FAK	cd05056	1.6e-86	626	900
STKc_TNIK	cd06637	3.8e-05	626	896
STKc_CDK12	cd07864	4.8e-10	626	917
PTKc_InsR_like	cd05032	7.8e-65	627	894
PTKc_Src_like	cd05034	4.6e-94	627	895
PTKc_Csk_like	cd05039	3e-65	627	895
PTK_CCK4	cd05046	4.4e-37	627	894
PTKc_Ror	cd05048	7.6e-63	627	895
PTKc_Trk	cd05049	1.7e-65	627	894
PTKc_Musk	cd05050	1.9e-70	627	894
PTKc_DDR	cd05051	1e-46	627	894
PTKc_FGFR	cd05053	1.1e-35	627	897
PTKc_Abl	cd05052	8.2e-82	627	896
PTKc_InsR	cd05061	1.4e-48	627	907
PTKc_IGF-1R	cd05062	8.8e-46	627	894
PTKc_EphR_A2	cd05063	1.6e-187	627	896
PTKc_EphR_A10	cd05064	1.4e-145	627	896
PTKc_Lck_Blk	cd05067	2.1e-75	627	895
PTKc_Frk_like	cd05068	7.1e-95	627	895
PTKc_Yes	cd05069	1.3e-71	627	895
PTKc_Fyn_Yrk	cd05070	3.1e-75	627	895
PTKc_Src	cd05071	2.1e-74	627	897
PTKc_Lyn	cd05072	1.7e-73	627	895
PTKc_Hck	cd05073	3e-75	627	895
PTKc_Csk	cd05082	9.3e-55	627	895
PTKc_Ror2	cd05091	5.3e-58	627	895
PTKc_TrkA	cd05092	7.4e-52	627	902
PTKc_TrkC	cd05094	6.7e-26	627	905
PTKc_DDR2	cd05095	1.3e-50	627	894
PTKc_DDR1	cd05096	2e-44	627	894
PTKc_DDR_like	cd05097	5.3e-53	627	894
PTKc_TrkB	cd05093	3.2e-47	627	904
PTKc_Ror1	cd05090	3.5e-60	627	895
PKc_MAPKK_Byr1_like	cd06620	2.2e-07	627	906
STKc_MST4	cd06640	9.6e-08	627	903
STKc_MST3	cd06641	6.5e-07	627	903
STKc_STK25-YSK1	cd06642	1.3e-07	627	903
STKc_STK10_LOK	cd06644	2.1e-06	627	912
STKc_TEY_MAPK_plant	cd07858	3.5e-06	627	974
PTKc_EphR	cd05033	3.7e-223	628	896
PTK_Ryk	cd05043	2.7e-24	628	895
PTKc_Tec_like	cd05059	1.8e-73	628	893
PTKc_EphR_B	cd05065	4.6e-230	628	896
PTKc_EphR_A	cd05066	3.8e-205	628	896
PTKc_Jak1_rpt2	cd05079	9.3e-39	628	896
PTKc_Jak2_Jak3_rpt2	cd05081	5e-39	628	896
PTKc_Chk	cd05083	1.1e-65	628	895
PTKc_Tie2	cd05088	2.3e-41	628	919
PTKc_Itk	cd05112	1.3e-75	628	893
PTKc_Btk_Bmx	cd05113	1.8e-75	628	893
PTKc_Tec_Rlk	cd05114	1.9e-75	628	893
PKc_MAPKK_plant_like	cd06623	7.9e-11	628	901
STKc_ERK1_2_like	cd07849	1.6e-06	628	947
STKc_MAPK15	cd07852	5.2e-05	628	896
STKc_PFTAIRE2	cd07870	0.00018	628	917
STKc_Sty1_Hog1	cd07856	1.4e-05	628	944
STKc_MAP4K3_like	cd06613	1.9e-10	629	893
STKc_PCTAIRE_like	cd07844	6.6e-06	629	917
STKc_BUR1	cd07866	3.9e-08	629	870
PTKc_Jak_rpt2	cd05038	9.9e-58	630	896
STKc_phototropin_lik	cd05574	1.1e-05	630	913
STKc_SLK_like	cd06611	5.8e-08	630	907
PKc_MKK3_6	cd06617	4e-07	630	907
STKc_SLK	cd06643	1.4e-06	630	910
STKc_CDK10	cd07845	9e-08	630	925
PK_STRAD	cd08216	0.00078	630	898
STKc_Nek6_Nek7	cd08224	8e-08	630	897
STKc_Nek6	cd08228	2.9e-06	630	897
STKc_Nek7	cd08229	7.9e-09	630	897
STKc_PKA	cd05580	1.7e-06	631	912
STKc_MAST	cd05609	0.00072	631	955
STKc_PRKX_like	cd05612	1.3e-06	631	931
STKc_MAPKKK	cd06606	2e-18	631	886
STKc_OSR1_SPAK	cd06610	1e-08	631	888
PKc_MEK	cd06615	5.6e-06	631	938
PKc_MKK5	cd06619	7.1e-05	631	920
STKc_MST3_like	cd06609	8.2e-10	631	903
STKc_MEKK3_like_1	cd06653	9.3e-05	631	901
STKc_NAK1_like	cd06917	4.9e-07	631	909
STKc_Pho85	cd07836	2.1e-06	631	917
STKc_CDK5	cd07839	8.4e-06	631	917
STKc_CDK1_euk	cd07861	3.9e-05	631	917
STKc_CDK2_3	cd07860	5e-05	631	917
STKc_PCTAIRE1	cd07873	0.00058	631	923
STKc_Nek1	cd08218	1.2e-05	631	896
SPS1	COG0515	7e-22	631	988
PTKc_RET	cd05045	3.4e-44	632	899
PKc_STE	cd05122	7.5e-14	632	887
STKc_GRK4_like	cd05605	3.8e-05	632	924
STKc_cPKC_alpha	cd05615	0.00057	632	958
STKc_MEKK3	cd06651	1.2e-05	632	888
STKc_CDK1_like	cd07835	8.6e-06	632	917
STKc_CDC2L1	cd07843	4.6e-06	632	917
STKc_NLK	cd07853	6.2e-06	632	978
STKc_TDY_MAPK_plant	cd07859	1.3e-06	632	969
STKc_Nek4	cd08223	1.1e-06	632	896
STKc_Nek5	cd08225	5.2e-05	632	892
PTKc_Axl_like	cd05035	3.7e-61	633	896
PTKc_Tyro3	cd05074	2.2e-54	633	896
PTKc_Axl	cd05075	1.3e-51	633	896
PTKc_Tyk2_rpt2	cd05080	5e-14	633	897
PTKc_Tie1	cd05089	1.7e-43	633	918
STKc_cPKC	cd05587	0.0002	633	948
STKc_PKN	cd05589	1.5e-05	633	957
STKc_myosinIII_like	cd06608	7.9e-08	633	896
PKc_MAPKK_Pek1_like	cd06621	1e-06	633	900
STKc_MAPKKK_Bck1_lik	cd06629	4.9e-11	633	886
STKc_CDK9_like	cd07840	1.9e-10	633	917
STKc_CDK6	cd07862	5.2e-05	633	917
STKc_Nek3	cd08219	8e-09	633	894
STKc_CMGC	cd05118	1.3e-09	634	888
PTKc_Srm_Brk	cd05148	3.9e-76	634	895
STKc_Yank1	cd05578	3.4e-07	634	895
STKc_PDK1	cd05581	1.1e-07	634	888
STKc_CRIK	cd05601	0.00046	634	930
STKc_MST1_2	cd06612	2.2e-12	634	888
STKc_MEKK3_like	cd06625	6.9e-09	634	894
STKc_Cdc7_like	cd06627	6.3e-16	634	888
STKc_MAK_like	cd07830	2.5e-07	634	885
STKc_MOK	cd07831	0.00049	634	917
STKc_CDKL	cd07833	0.00014	634	892
STKc_MAPK	cd07834	2.1e-08	634	944
STKc_CdkB_plant	cd07837	4.6e-05	634	918
STKc_CDK4_6_like	cd07838	1.8e-05	634	875
STKc_CDK8_like	cd07842	0.00037	634	876
STKc_CCRK	cd07832	1.1e-06	634	885
STKc_CDK7	cd07841	1.8e-08	634	889
STKc_CDKL1_4	cd07847	2.2e-06	634	921
STKc_CDK_like	cd07829	4.9e-11	634	917
STKc_MPK1	cd07857	5.4e-06	634	904
STKc_CDK4	cd07863	7.1e-06	634	917
STKc_Nek	cd08215	2.7e-15	634	895
STKc_Nek2	cd08217	3.5e-07	634	896
STKc_Nek8	cd08220	1.4e-05	634	896
STKc_FA2-like	cd08529	5.4e-07	634	901
STKc_CNK2-like	cd08530	4.1e-05	634	892
STKc_Nek10	cd08528	4.3e-06	634	894
STKc_Nek11	cd08222	1.6e-07	635	896
STKc_RSK_N	cd05582	2.2e-05	636	947
STKc_p70S6K	cd05584	0.00016	636	959
PKc_MKK4	cd06616	2.1e-07	636	912
PKc_MAPKK_PBS2_like	cd06622	1.4e-06	636	950
STKc_MEKK4	cd06626	2.2e-07	636	876
PTKc	cd00192	9.8e-129	637	893
PTK_Jak_rpt1	cd05037	1.1e-10	637	893
PTKc_Ack_like	cd05040	8.8e-69	637	894
PTKc_Aatyk	cd05042	5.5e-15	637	894
PTKc_Tie	cd05047	2.5e-49	637	897
PTKc_c-ros	cd05044	2.8e-62	637	894
PTKc_Fes_like	cd05041	1e-89	637	894
PTKc_Met_Ron	cd05058	1.2e-61	637	898
PTKc_Syk_like	cd05060	1e-84	637	897
PTK_Jak1_rpt1	cd05077	5.8e-10	637	893
PTK_Jak2_Jak3_rpt1	cd05078	1.7e-11	637	893
PTKc_Fes	cd05084	7.1e-74	637	894
PTKc_Fer	cd05085	3.2e-75	637	894
PTKc_Aatyk2	cd05086	3.2e-18	637	894
PTKc_Aatyk1_Aatyk3	cd05087	1.1e-19	637	894
PTKc_Syk	cd05116	2e-62	637	897
STKc_PKC	cd05570	9.5e-05	637	912
STKc_PKB	cd05571	5.4e-06	637	959
STKc_SGK	cd05575	0.00061	637	952
STKc_nPKC_epsilon	cd05591	0.00056	637	958
STKc_nPKC_theta_delt	cd05592	0.00028	637	959
STKc_SGK1	cd05602	0.00057	637	954
STKc_SGK2	cd05603	0.0001	637	958
STKc_nPKC_theta	cd05619	0.00034	637	949
PKc_MAPKK	cd06605	1.8e-08	637	890
STKc_MAPKKK_Byr2_lik	cd06628	7.3e-11	637	894
STKc_MEKK1	cd06630	1.4e-06	637	891
STKc_YSK4	cd06631	1.9e-08	637	895
STKc_MEKK1_plant	cd06632	9.7e-10	637	889
STKc_CDKL2_3	cd07846	5.8e-06	637	891
STKc_Nek9	cd08221	1.5e-07	638	897
PKc	cd00180	5.7e-59	639	892
STKc_AGC	cd05123	4.5e-07	639	885
PTKc_Zap-70	cd05115	5.4e-74	639	897
STKc_MAST_like	cd05579	4.2e-06	639	891
STKc_YPK1_like	cd05585	4.5e-05	639	956
STKc_cGK_PKG	cd05572	3.2e-05	639	877
STKc_MAPK4_6	cd07854	0.00012	639	945
	cd00166	2.4e-24	924	987
Ephrin_lbd	pfam01404	7.3e-124	39	212
fn3	pfam00041	4.3e-16	341	435
fn3	pfam00041	2.2e-17	454	535
Pkinase	pfam00069	1.1e-40	633	892
SAM_1	pfam00536	5.6e-33	923	987
EPH_lbd	smart00615	1.4e-119	39	211
GCC2_GCC3	pfam07699	0.00057	274	320
FN3	smart00060	1e-11	340	435
FN3	smart00060	1.1e-15	453	532
Pkinase_Tyr	pfam07714	3.7e-144	633	892
TyrKc	smart00219	1.9e-139	633	892
STYKc	smart00221	1.4e-54	633	925
S_TKc	smart00220	2.2e-42	643	896
SAM_2	pfam07647	8.9e-27	922	987
SAM	smart00454	3.3e-26	922	989

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_042177	Polymorphism	p.ARG440CYS	N/A
Swiss-Prot	VAR_042176	Polymorphism	p.ARG168LEU	N/A
Swiss-Prot	VAR_042180	Polymorphism	p.ARG724TRP	N/A
Swiss-Prot	VAR_042179	Polymorphism	p.ILE601LEU	N/A
Swiss-Prot	VAR_042178	Polymorphism	p.ILE579VAL	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258