Results for the protein: Q6PHW0

Results for the Protein: Q6PHW0

91207083

389434

IYD

NCBI, UniProt

IYD1_HUMAN RecName: Full=Iodotyrosine dehalogenase 1; Short=IYD-1; Flags: Precursor

Known Diseases associated with this Protein:
THYROID DYSHORMONOGENESIS 4
THYROID DYSHORMONOGENESIS 4 (TDH4)

5

3

3

2

3

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: NfnB - COG0778 NADH_oxidase - cd03370 NADPH_oxidoreductase - cd02151 iodotyrosine_dehalog - cd02144 Nitroreductase - cd02136 Nitroreductase_3 - cd02139 NADPH_oxidoreductase - cd02150 BluB - cd02145 Arsenite_oxidase - cd02135 Nitroreductase_1 - cd02137 NADH_nitroreductase - cd02143 Nitroreductase - pfam00881 Nitro_FMN_reductase - cd02062	Swiss-Prot Protein: Q6PHW0 Identical to: NP_981932 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Nitroreductase	cd02136	7.8e-07	93	286
Nitroreductase_3	cd02139	3.9e-11	93	286
iodotyrosine_dehalog	cd02144	5.2e-148	93	285
NADPH_oxidoreductase	cd02151	1.5e-06	93	277
NADH_oxidase	cd03370	4.1e-05	93	282
Arsenite_oxidase	cd02135	3.3e-05	94	267
Nitroreductase_1	cd02137	2.5e-07	94	285
BluB	cd02145	5e-09	94	287
NADPH_oxidoreductase	cd02150	1.6e-09	94	285
NADH_nitroreductase	cd02143	9.2e-06	96	286
Nitro_FMN_reductase	cd02062	3.2e-43	97	267
Nitroreductase	pfam00881	2.2e-24	97	267

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs73619510	Polymorphism	p.ARG246GLN	N/A
Swiss-Prot	VAR_045963	Disease	p.ARG101TRP	Thyroid dyshormonogenesis 4 (TDH4)
dbSNP	rs36063028	Polymorphism	p.GLU271LYS	N/A
Swiss-Prot	VAR_045965	Disease	p.ILE116THR	Thyroid dyshormonogenesis 4 (TDH4)
Swiss-Prot	VAR_025785	Polymorphism	p.LEU260PRO	N/A
OMIM	612025.0004	Disease	p.ALA220TYR	THYROID DYSHORMONOGENESIS 4
OMIM	612025.0001	Disease	p.ARG101TRP	THYROID DYSHORMONOGENESIS 4
OMIM	612025.0003	Disease	p.ILE116THR	THYROID DYSHORMONOGENESIS 4

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