Results for the protein: O94887

Results for the Protein: O94887

93204574

9855

FARP2

NCBI, UniProt

FARP2_HUMAN RecName: Full=FERM, RhoGEF and pleckstrin domain-containing protein 2; AltName: Full=FERM domain including RhoGEF; Short=FIR; AltName: Full=Pleckstrin homology domain-containing family C member 3; Short=PH domain-containing family C member 3

			0 5 0 5 0

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

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Default View: B41 - smart00295 FERM_N - pfam09379 FERM_M - pfam00373 FERM_C-lobe - cd00836 FERM_C - pfam09380 FA - pfam08736 RhoGEF - cd00160 RhoGEF - smart00325 RhoGEF - pfam00621 PH_Phafin2-like - cd01218 PH1_FGD1 - cd01219 PH1_FARP1-like - cd01220 PH - pfam00169 PH - smart00233 PH-like - cd00900 PH - cd00821 PH_CNK_mammalian-lik - cd01260 PH_GRP1-like - cd01252 - cd01246 PH_AGAP - cd01250	Swiss-Prot Protein: O94887 Identical to: NP_055623 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
RhoGEF	cd00160	2.8e-60	536	724
PH_Phafin2-like	cd01218	1.8e-11	753	857
PH1_FGD1	cd01219	9.8e-08	755	853
PH1_FARP1-like	cd01220	9e-78	755	853
PH	cd00821	1e-17	758	850
PH-like	cd00900	1.7e-10	758	850
PH_GRP1-like	cd01252	0.001	931	1037
PH_CNK_mammalian-lik	cd01260	0.00011	931	1024
PH	cd00821	5.2e-18	932	1024
	cd01246	2.4e-05	932	1024
PH_AGAP	cd01250	0.00024	934	1024
FERM_M	pfam00373	1.5e-28	131	234
RhoGEF	pfam00621	1.2e-49	540	725
PH	pfam00169	8.3e-12	756	852
PH	pfam00169	7.5e-17	930	1026
B41	smart00295	1.8e-59	41	234
FERM_N	pfam09379	2.8e-31	48	125
FERM_C	pfam09380	4e-40	238	325
FA	pfam08736	2e-18	332	378
RhoGEF	smart00325	3e-64	539	725
PH	smart00233	1.5e-18	756	852
PH	smart00233	5.4e-18	930	1026

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs61740951	Polymorphism	p.ARG729TRP	N/A
dbSNP	rs16843643	Polymorphism	p.LYS185ASN	N/A
dbSNP	rs75022667	Polymorphism	p.SER896PHE	N/A
dbSNP	rs757978	Polymorphism	p.THR260ILE	N/A
dbSNP	rs41342147	Polymorphism	p.VAL643ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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