Results for the protein: P16591

Results for the Protein: P16591

97536202

2241

FER

NCBI, UniProt

FER_HUMAN RecName: Full=Tyrosine-protein kinase Fer; AltName: Full=Feline encephalitis virus-related kinase FER; AltName: Full=Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; AltName: Full=Proto-oncogene c-Fer; AltName: Full=Tyrosine kinase 3; AltName: Full=p94-Fer

			0 8 0 0 8

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Swiss-Prot Protein: P16591

Identical to: NP_005237

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
F-BAR_Fes_Fer	cd07657	4.8e-139	5	238
F-BAR_Fer	cd07686	3.1e-182	5	238
F-BAR_Fes	cd07685	3.1e-76	9	238
FCH_F-BAR	cd07610	8.9e-17	10	249
F-BAR_FCHSD1	cd07678	0.00086	11	237
SH2	cd00173	1.6e-31	459	550
PTKc_CSF-1R	cd05106	1.6e-39	529	822
PTKc_PDGFR	cd05055	1.6e-36	532	818
PTKc_Kit	cd05104	1.9e-29	532	821
PTKc_PDGFR_alpha	cd05105	6.9e-20	532	820
PTKc_PDGFR_beta	cd05107	1.1e-21	532	822
STKc_PAK5	cd06658	0.00035	536	822
STKc_myosinIIIA	cd06638	2.2e-07	538	816
STKc_PAK6	cd06659	5.2e-05	538	822
STKc_TAO1	cd06635	0.0007	539	822
STKc_MAP4K4_6	cd06636	2.3e-05	541	816
PTKc_FGFR1	cd05098	1.1e-51	543	820
PKc_MKK7	cd06618	5.9e-08	543	820
STKc_p38	cd07851	5.3e-05	546	819
STKc_myosinIIIB	cd06639	6.7e-06	547	818
STKc_PAK1	cd06654	0.00032	548	822
STKc_PAK3	cd06656	0.00046	548	822
STKc_PAK2	cd06655	0.00046	548	819
PTKc_FGFR	cd05053	4.4e-68	550	822
PTKc_FGFR4	cd05099	3.4e-54	550	822
PTKc_FGFR3	cd05100	4.9e-39	550	820
PTKc_FGFR2	cd05101	2.4e-50	550	822
STKc_TAO	cd06607	0.00075	551	822
STKc_TAO2	cd06634	0.00017	551	820
STKc_STK10_LOK	cd06644	1.4e-06	552	822
STKc_PAK	cd06614	1.4e-12	553	821
STKc_MAP4K3	cd06645	1.3e-06	553	814
STKc_MAP4K5	cd06646	2.2e-05	553	815
STKc_CDK9	cd07865	5.1e-08	553	807
STKc_ASK	cd06624	2.1e-12	554	816
STKc_CDK12	cd07864	1.1e-07	554	815
PTKc_VEGFR	cd05054	1.2e-29	555	821
PTKc_EGFR_like	cd05057	1.7e-54	555	818
PTKc_VEGFR3	cd05102	3.2e-35	555	821
PTKc_VEGFR2	cd05103	2.7e-30	555	821
PTK_HER3	cd05111	1.1e-42	555	818
STKc_PAK_II	cd06648	1.6e-06	555	821
PTKc_InsR_like	cd05032	4.2e-72	556	816
PTKc_Src_like	cd05034	1.8e-105	556	817
PTKc_Csk_like	cd05039	5.6e-94	556	817
PTK_Ryk	cd05043	5.2e-24	556	821
PTKc_Abl	cd05052	6.2e-94	556	818
PTKc_FAK	cd05056	8.3e-99	556	822
PTKc_Lck_Blk	cd05067	1.5e-73	556	817
PTKc_Frk_like	cd05068	3.8e-97	556	817
PTKc_Yes	cd05069	1e-73	556	817
PTKc_IGF-1R	cd05062	1.7e-58	556	819
PTKc_Src	cd05071	1.7e-73	556	819
PTKc_Lyn	cd05072	4e-75	556	817
PTKc_Csk	cd05082	2.5e-74	556	817
PTKc_Chk	cd05083	1e-86	556	817
PTKc_InsR	cd05061	4.7e-58	556	822
PTKc_Fyn_Yrk	cd05070	1.6e-77	556	817
PTKc_Hck	cd05073	1.4e-77	556	817
PTKc_TrkB	cd05093	1.3e-42	556	822
PTKc_Srm_Brk	cd05148	1.6e-91	556	817
STKc_ERK1_2_like	cd07849	4.5e-05	556	819
PTK_CCK4	cd05046	3.4e-39	557	816
PTKc_Trk	cd05049	3.7e-58	557	816
PTKc_Tie2	cd05088	2.7e-51	557	822
PTKc_Ror	cd05048	8.9e-57	557	817
PTKc_HER2	cd05109	5.9e-44	557	822
PTKc_Tec_Rlk	cd05114	1.8e-80	557	815
PTKc_EGFR	cd05108	3.7e-28	557	822
PTKc_HER4	cd05110	2.9e-32	557	822
PTKc_EphR	cd05033	1.8e-89	558	818
PTKc_ALK_LTK	cd05036	7e-84	558	816
PTKc_Musk	cd05050	8.7e-67	558	816
PTKc_Tec_like	cd05059	9.1e-89	558	815
PTKc_EphR_A2	cd05063	6.2e-70	558	821
PTKc_EphR_A10	cd05064	2.8e-62	558	818
PTKc_EphR_B	cd05065	6.5e-73	558	818
PTKc_EphR_A	cd05066	1.8e-75	558	818
PTKc_Jak2_Jak3_rpt2	cd05081	2.3e-43	558	818
PTKc_Ror2	cd05091	4.4e-46	558	817
PTKc_TrkA	cd05092	2e-49	558	816
PTKc_TrkC	cd05094	2.8e-30	558	822
PTKc_DDR2	cd05095	5.7e-43	558	816
PTKc_DDR_like	cd05097	1.5e-44	558	816
PTKc_Ror1	cd05090	1.2e-51	558	817
PTKc_DDR1	cd05096	9e-32	558	816
PTKc_Itk	cd05112	1.8e-87	558	815
PTKc_Btk_Bmx	cd05113	1.1e-83	558	815
STKc_SLK_like	cd06611	1.7e-08	558	820
PKc_MKK4	cd06616	2.1e-07	558	821
STKc_TNIK	cd06637	2.5e-07	558	816
STKc_SLK	cd06643	3.7e-07	558	821
PKc_MAPKK_Byr1_like	cd06620	2.4e-05	558	822
STKc_BUR1	cd07866	9.1e-08	558	807
PTKc_Jak_rpt2	cd05038	5.2e-76	559	818
STKc_phototropin_lik	cd05574	1.7e-05	559	793
STKc_MST1_2	cd06612	7.2e-12	559	816
STKc_MAP4K3_like	cd06613	1.1e-10	559	815
PKc_MAPKK_plant_like	cd06623	4.3e-13	559	821
STKc_MST4	cd06640	5.2e-08	559	820
STKc_MST3	cd06641	4.4e-07	559	821
STKc_PAK4	cd06657	0.00078	559	821
STKc_STK25-YSK1	cd06642	3.9e-08	559	821
STKc_PCTAIRE_like	cd07844	3.9e-06	559	816
STKc_CDK2_3	cd07860	3.1e-05	559	815
STKc_CDK4	cd07863	0.00013	559	815
STKc_PFTAIRE2	cd07870	7.1e-05	559	822
STKc_PCTAIRE2	cd07872	0.0006	559	820
STKc_PCTAIRE1	cd07873	0.00042	559	819
STKc_PFTAIRE1	cd07869	0.00029	559	819
PTKc_Jak1_rpt2	cd05079	3.5e-39	560	818
PTKc_Tie1	cd05089	1.1e-56	560	822
PKc_MAPKK_PBS2_like	cd06622	8.9e-08	560	820
STKc_MEKK2	cd06652	9.4e-05	560	817
STKc_MEKK3_like_1	cd06653	8.1e-06	560	816
PK_STRAD	cd08216	9e-05	560	819
STKc_Nek6_Nek7	cd08224	2.3e-08	560	822
STKc_Nek6	cd08228	2e-08	560	816
STKc_Nek7	cd08229	6.5e-10	560	816
STKc_Nek5	cd08225	1.2e-06	560	816
PTKc_DDR	cd05051	1.2e-36	561	816
STKc_ROCK_NDR_like	cd05573	7.3e-05	561	818
STKc_PKA	cd05580	1.1e-06	561	810
STKc_PDK1	cd05581	4.7e-15	561	812
STKc_CRIK	cd05601	0.00089	561	808
STKc_PRKX_like	cd05612	1.3e-05	561	811
PKc_MAPKK	cd06605	3.6e-09	561	822
STKc_myosinIII_like	cd06608	3.1e-10	561	816
STKc_MST3_like	cd06609	7.1e-10	561	821
STKc_OSR1_SPAK	cd06610	3.7e-10	561	816
PKc_MEK	cd06615	8.1e-08	561	821
PKc_MKK3_6	cd06617	1.4e-08	561	822
PKc_MKK5	cd06619	0.00016	561	820
PKc_MAPKK_Pek1_like	cd06621	1.7e-07	561	822
STKc_CDKL1_4	cd07847	9.1e-07	561	816
STKc_MAPK15	cd07852	0.00041	561	817
STKc_PCTAIRE3	cd07871	0.00013	561	817
SPS1	COG0515	5.2e-09	561	822
PTKc_RET	cd05045	2.3e-55	562	819
PKc_STE	cd05122	6.2e-15	562	815
STKc_Yank1	cd05578	4.7e-09	562	817
STKc_MSK_N	cd05583	0.00028	562	822
STKc_cPKC	cd05587	0.0002	562	822
STKc_GRK4_like	cd05605	0.00019	562	822
STKc_cPKC_alpha	cd05615	0.00011	562	818
STKc_cPKC_beta	cd05616	0.00084	562	822
STKc_MAPKKK	cd06606	7.1e-20	562	817
STKc_Cdc7_like	cd06627	1.5e-14	562	816
STKc_MAPKKK_Byr2_lik	cd06628	5.9e-21	562	816
STKc_MAPKKK_Bck1_lik	cd06629	1.7e-14	562	808
STKc_CCRK	cd07832	1.6e-08	562	822
STKc_Pho85	cd07836	8.6e-05	562	815
STKc_CDK1_euk	cd07861	3.9e-05	562	816
STKc_Nek1	cd08218	8.3e-06	562	816
STKc_Nek3	cd08219	7e-09	562	816
STKc_Nek11	cd08222	2.6e-16	562	816
STKc_Nek4	cd08223	7e-09	562	816
STKc_Nek10	cd08528	7e-09	562	816
STKc_FA2-like	cd08529	2.6e-09	562	816
STKc_CNK2-like	cd08530	1.2e-09	562	815
PTKc_Axl_like	cd05035	6e-66	563	818
PTKc_Tyro3	cd05074	8e-64	563	818
PTKc_Axl	cd05075	2.2e-54	563	818
STKc_PKN	cd05589	9.4e-05	563	822
STKc_CDK9_like	cd07840	1.5e-10	563	807
STKc_CDK_like	cd07829	1.2e-11	564	807
STKc_MPK1	cd07857	2.4e-05	564	816
STKc_Sty1_Hog1	cd07856	0.00016	564	820
STKc_CDK8_like	cd07842	5.5e-05	564	819
STKc_CDK7	cd07841	5e-09	564	811
STKc_MEKK3_like	cd06625	1.8e-10	565	816
STKc_MEKK4	cd06626	1.1e-10	565	816
STKc_MAK_like	cd07830	5.4e-08	565	816
STKc_MAPK	cd07834	7.9e-06	565	817
STKc_CDK4_6_like	cd07838	2.6e-07	565	807
STKc_MEKK1	cd06630	6.7e-08	566	815
STKc_YSK4	cd06631	5.9e-11	566	816
STKc_MEKK1_plant	cd06632	1.4e-11	566	810
STKc_MEKK3	cd06651	4e-06	566	817
STKc_CDK10	cd07845	3.5e-05	566	798
PTKc	cd00192	7.6e-140	567	815
PTKc_Ack_like	cd05040	3.3e-68	567	816
PTKc_Fes_like	cd05041	6e-218	567	816
PTKc_Aatyk	cd05042	3.4e-15	567	816
PTKc_c-ros	cd05044	8.9e-80	567	816
PTKc_Tie	cd05047	9.2e-64	567	819
PTKc_Met_Ron	cd05058	6.3e-66	567	820
PTKc_Syk_like	cd05060	1.4e-79	567	819
PTK_Jak1_rpt1	cd05077	2.9e-11	567	815
PTK_Jak2_Jak3_rpt1	cd05078	3.3e-12	567	815
PTK_Tyk2_rpt1	cd05076	3.7e-07	567	815
PTKc_Tyk2_rpt2	cd05080	2.2e-25	567	819
PTKc_Fes	cd05084	1e-157	567	816
PTKc_Fer	cd05085	1.9e-222	567	816
PTKc_Aatyk2	cd05086	1e-16	567	816
PTKc_Aatyk1_Aatyk3	cd05087	1e-26	567	816
PTK_Jak_rpt1	cd05037	3.1e-12	567	815
PTKc_Syk	cd05116	8.5e-69	567	819
STKc_CMGC	cd05118	9.3e-11	567	816
STKc_PKC	cd05570	3.5e-08	567	822
STKc_RSK_N	cd05582	0.00092	567	817
STKc_nPKC_theta_delt	cd05592	0.00035	567	820
STKc_nPKC_theta	cd05619	4.4e-06	567	822
STKc_NAK1_like	cd06917	1.7e-09	567	822
STKc_CDKL	cd07833	9.5e-07	567	816
STKc_CDK1_like	cd07835	7.6e-06	567	816
STKc_CdkB_plant	cd07837	1.2e-07	567	808
STKc_CDK5	cd07839	1.6e-05	567	815
STKc_CDKL2_3	cd07846	2.8e-07	567	815
STKc_Nek2	cd08217	4.3e-10	567	816
STKc_Nek8	cd08220	2.9e-06	567	816
STKc_Nek	cd08215	4.5e-16	567	816
STKc_Nek9	cd08221	1.3e-05	568	816
PKc	cd00180	1.5e-67	569	814
PTKc_Zap-70	cd05115	1.7e-67	569	819
STKc_AGC	cd05123	3.4e-10	569	812
STKc_cGK_PKG	cd05572	1.1e-09	569	814
STKc_GRK	cd05577	9e-05	569	818
STKc_MAST_like	cd05579	4.6e-08	569	812
STKc_GRK7	cd05607	3.7e-05	569	820
STKc_GRK1	cd05608	0.00033	569	819
STKc_MOK	cd07831	2.4e-07	569	807
STKc_CDC2L1	cd07843	3.8e-06	571	807
FCH	pfam00611	8.6e-21	1	92
SH2	pfam00017	1.9e-32	460	531
Pkinase	pfam00069	5.6e-42	563	814
FCH	smart00055	2.4e-31	1	88
SH2	smart00252	4.8e-30	458	537
Pkinase_Tyr	pfam07714	9.4e-153	563	814
STYKc	smart00221	1.1e-60	563	816
TyrKc	smart00219	1.5e-143	563	814
S_TKc	smart00220	2.7e-50	573	816

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041694	Polymorphism	p.ALA443PRO	N/A
Swiss-Prot	VAR_041692	Polymorphism	p.GLU404GLN	N/A
Swiss-Prot	VAR_041696	Polymorphism	p.GLU813GLN	N/A
Swiss-Prot	VAR_051695	Polymorphism	p.ILE507THR	N/A
Swiss-Prot	VAR_006282	Polymorphism	p.LEU439VAL	N/A
Swiss-Prot	VAR_041693	Polymorphism	p.MET412VAL	N/A
Swiss-Prot	VAR_041695	Polymorphism	p.TRP460CYS	N/A
Swiss-Prot	VAR_041691	Polymorphism	p.VAL128PHE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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