Results for the protein: P57058

Results for the Protein: P57058

9973393

30811

HUNK

NCBI, UniProt

HUNK_HUMAN RecName: Full=Hormonally up-regulated neu tumor-associated kinase; AltName: Full=B19; AltName: Full=Serine/threonine-protein kinase MAK-V

			0 4 0 1 3

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: P57058

Identical to: NP_055401

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK2	cd05621	1.2e-07	16	380
STKc_TAO1	cd06635	3e-07	28	358
STKc_JNK2	cd07876	4.9e-07	30	436
STKc_JNK3	cd07874	1.1e-06	34	436
STKc_myosinIIIB	cd06639	2.4e-07	35	321
STKc_ROCK	cd05596	5.7e-07	37	380
STKc_MAP4K4_6	cd06636	1.6e-06	39	320
PTKc_EGFR_like	cd05057	1.9e-06	41	312
STKc_PAK	cd06614	3.4e-22	42	332
STKc_TAO3	cd06633	2.2e-05	42	357
STKc_p38alpha_MAPK14	cd07877	3.2e-06	42	367
PTKc_Yes	cd05069	4.6e-06	43	318
PTKc_Lck_Blk	cd05067	0.00037	43	343
PTKc_FGFR1	cd05098	2.3e-05	43	327
PTKc_FGFR2	cd05101	1.1e-05	43	323
STKc_PAK5	cd06658	2.4e-08	43	339
STKc_JNK	cd07850	1.2e-07	43	434
PTKc_FGFR	cd05053	6.4e-05	44	321
PTKc_FGFR4	cd05099	1e-06	44	346
PTKc_FGFR3	cd05100	0.00044	44	351
STKc_myosinIIIA	cd06638	5e-08	44	320
STKc_p38delta_MAPK13	cd07879	4.8e-05	44	367
STKc_PAK_I	cd06647	1.3e-22	45	339
STKc_PAK4	cd06657	4.3e-09	45	339
STKc_TAO	cd06607	6.4e-07	46	358
STKc_TAO2	cd06634	9.8e-09	46	359
STKc_PAK_II	cd06648	4.2e-12	46	333
STKc_PAK6	cd06659	1.9e-10	46	341
STKc_PAK1	cd06654	1.1e-12	47	360
STKc_PAK2	cd06655	1.5e-15	47	337
STKc_PAK3	cd06656	9.7e-12	47	362
PTKc_EGFR	cd05108	3.9e-06	48	357
PTKc_HER4	cd05110	9.9e-05	48	342
PKc_MKK7	cd06618	3.7e-10	48	340
STKc_p38	cd07851	1.4e-10	48	359
STKc_CDK9	cd07865	4.1e-13	48	320
STKc_p38beta_MAPK11	cd07878	2.7e-06	48	359
STKc_p38gamma_MAPK12	cd07880	2.8e-08	48	359
PTKc_Chk	cd05083	8.9e-08	49	322
PTKc_Tie2	cd05088	2.7e-05	49	345
STKc_ASK	cd06624	1.6e-18	49	320
STKc_MRCK_alpha	cd05623	5.1e-09	50	383
STKc_MRCK_beta	cd05624	4.8e-08	50	382
PKc_MKK5	cd06619	6e-05	50	344
STKc_MAP4K3	cd06645	6.9e-08	51	319
STKc_MAP4K5	cd06646	6.6e-08	51	319
STKc_STK10_LOK	cd06644	1.8e-09	52	340
STKc_ERK5	cd07855	2e-12	52	358
STKc_Sty1_Hog1	cd07856	1.4e-09	52	355
STKc_BUR1	cd07866	5.6e-14	52	320
STKc_JNK1	cd07875	1.4e-05	52	425
STKc_phototropin_lik	cd05574	9.2e-13	53	328
STKc_CDK10	cd07845	1e-12	53	335
PTKc_Jak_rpt2	cd05038	4.9e-11	54	351
PTKc_Trk	cd05049	9.4e-06	54	322
PTKc_Lyn	cd05072	4.7e-05	54	318
PTKc_Jak1_rpt2	cd05079	1.4e-06	54	344
PTKc_Jak2_Jak3_rpt2	cd05081	2.4e-07	54	342
PTKc_Tyk2_rpt2	cd05080	6.7e-08	54	336
PTKc_TrkB	cd05093	0.00028	54	333
PTKc_TrkA	cd05092	0.00059	54	326
STKc_TNIK	cd06637	1.5e-08	54	320
STKc_CDK12	cd07864	1.8e-11	54	320
STKc_PCTAIRE2	cd07872	2e-07	54	344
STKc_PCTAIRE1	cd07873	1.5e-07	54	361
PTKc_Abl	cd05052	2.9e-11	55	319
PTKc_Frk_like	cd05068	2.2e-14	55	324
PTKc_Fyn_Yrk	cd05070	5.4e-05	55	319
PTKc_Src	cd05071	2e-05	55	325
PTKc_Hck	cd05073	0.00011	55	318
PTKc_Csk	cd05082	1.3e-06	55	323
PTKc_IGF-1R	cd05062	0.00097	55	317
STKc_PCTAIRE_like	cd07844	4.5e-13	55	320
STKc_TEY_MAPK_plant	cd07858	1.5e-12	55	365
STKc_PFTAIRE1	cd07869	3.6e-05	55	361
STKc_PFTAIRE2	cd07870	1.3e-08	55	353
STKc_PCTAIRE3	cd07871	8.3e-09	55	320
PTKc_ALK_LTK	cd05036	0.00015	56	313
PTKc_FAK	cd05056	2.6e-10	56	328
PTKc_HER2	cd05109	4.7e-07	56	331
PTKc_Btk_Bmx	cd05113	1.8e-09	56	319
PTK_HER3	cd05111	2e-06	56	312
STKc_SLK	cd06643	1.4e-09	56	338
PTKc_EphR_A2	cd05063	0.00075	57	320
PTKc_EphR_A10	cd05064	0.00036	57	319
STKc_MAP4K3_like	cd06613	2.4e-13	57	319
STKc_CDC2L1	cd07843	4.2e-12	57	320
PTKc_InsR_like	cd05032	2.3e-06	58	317
PKc_MKK4	cd06616	2.6e-08	58	339
STKc_ERK1_2_like	cd07849	8.2e-11	58	353
STKc_Nek6_Nek7	cd08224	2.7e-11	58	321
STKc_Nek6	cd08228	1.8e-16	58	320
STKc_Nek7	cd08229	3.6e-12	58	321
PTKc_Itk	cd05112	6.1e-07	59	319
PTKc_Tec_Rlk	cd05114	2.7e-07	59	319
STKc_ROCK_NDR_like	cd05573	3.2e-14	59	360
STKc_PKA	cd05580	1.6e-15	59	349
STKc_PDK1	cd05581	2e-24	59	320
STKc_DMPK_like	cd05597	8.9e-09	59	380
STKc_CRIK	cd05601	1.9e-10	59	360
STKc_MST3_like	cd06609	1.6e-12	59	339
STKc_MST4	cd06640	6.9e-07	59	339
STKc_STK25-YSK1	cd06642	1.1e-09	59	342
STKc_MST3	cd06641	2e-07	59	339
STKc_MEKK2	cd06652	1.6e-09	59	321
STKc_CDKL	cd07833	2.2e-15	59	320
SPS1	COG0515	3.1e-66	59	468
PTKc_EphR	cd05033	7.3e-06	60	301
PTKc_Src_like	cd05034	6.6e-08	60	318
PTKc_Musk	cd05050	4.2e-05	60	322
PTKc_EphR_B	cd05065	0.00022	60	320
PTKc_Tie1	cd05089	0.00016	60	328
PTKc_DDR2	cd05095	0.00079	60	322
STKc_Yank1	cd05578	1.6e-18	60	320
STKc_MSK_N	cd05583	1.1e-20	60	326
STKc_cPKC	cd05587	3.9e-22	60	390
STKc_LATS	cd05598	1e-08	60	379
STKc_MAST	cd05609	1.6e-11	60	376
STKc_PRKX_like	cd05612	6.3e-12	60	364
STKc_MSK2_N	cd05614	1.2e-12	60	364
STKc_cPKC_beta	cd05616	7.7e-11	60	378
STKc_MSK1_N	cd05613	2.3e-15	60	335
STKc_LATS1	cd05625	7.2e-07	60	386
STKc_LATS2	cd05626	7e-06	60	389
STKc_NDR1	cd05628	1.9e-08	60	389
STKc_NDR_like_fungal	cd05629	4.4e-06	60	397
STKc_NDR2	cd05627	5.9e-07	60	410
PKc_MAPKK	cd06605	2.5e-12	60	325
STKc_MAPKKK	cd06606	8.6e-55	60	320
PKc_MEK	cd06615	1.9e-06	60	367
PKc_MKK3_6	cd06617	4.2e-09	60	337
PKc_MAPKK_Pek1_like	cd06621	2e-08	60	330
PKc_MAPKK_PBS2_like	cd06622	9.8e-08	60	358
PKc_MAPKK_plant_like	cd06623	3.5e-16	60	326
STKc_MEKK3_like	cd06625	1.7e-26	60	320
STKc_Cdc7_like	cd06627	3.3e-21	60	320
STKc_MAPKKK_Byr2_lik	cd06628	5.6e-32	60	320
STKc_MEKK1	cd06630	3.7e-11	60	318
STKc_MEKK3	cd06651	1.4e-12	60	322
STKc_MEKK3_like_1	cd06653	3.5e-12	60	320
STKc_MAPK	cd07834	1.6e-13	60	351
STKc_Pho85	cd07836	2.6e-20	60	320
STKc_CDK7	cd07841	8.4e-18	60	339
STKc_CCRK	cd07832	2.4e-18	60	321
STKc_CDK8_like	cd07842	1.6e-07	60	320
STKc_CDKL1_4	cd07847	6.3e-15	60	320
STKc_CDKL5	cd07848	5.9e-05	60	320
STKc_MPK1	cd07857	1.4e-09	60	351
STKc_TDY_MAPK_plant	cd07859	4.3e-09	60	359
STKc_Nek	cd08215	6.8e-44	60	320
STKc_Nek3	cd08219	1.6e-29	60	320
STKc_Nek9	cd08221	9.6e-14	60	320
STKc_Nek11	cd08222	2.6e-18	60	320
STKc_Nek4	cd08223	4.1e-24	60	320
STKc_Nek5	cd08225	1.8e-19	60	320
STKc_Nek10	cd08528	9.2e-09	60	318
STKc_CNK2-like	cd08530	1.4e-12	60	320
STKc_FA2-like	cd08529	6.8e-14	60	320
PTKc_Csk_like	cd05039	3.1e-08	61	292
PTKc_RET	cd05045	0.00028	61	318
PKc_STE	cd05122	2e-26	61	319
STKc_GRK4_like	cd05605	7.4e-15	61	351
STKc_cPKC_alpha	cd05615	1.7e-14	61	382
STKc_GRK6	cd05630	1.3e-08	61	351
STKc_GRK4	cd05631	9.9e-09	61	351
STKc_GRK5	cd05632	6.5e-10	61	351
STKc_CDK_like	cd07829	7.9e-22	61	320
STKc_MAK_like	cd07830	1.2e-16	61	320
STKc_CDK4_6_like	cd07838	4.1e-10	61	320
STKc_CDK9_like	cd07840	1.2e-18	61	320
STKc_MAPK4_6	cd07854	6.4e-08	61	361
STKc_CDK2_3	cd07860	2.3e-13	61	320
STKc_CDK1_euk	cd07861	1e-12	61	349
STKc_CDK4	cd07863	2.1e-05	61	320
STKc_Nek1	cd08218	2.6e-27	61	320
PTK_Ryk	cd05043	2.3e-08	62	300
PTKc_Tec_like	cd05059	9.7e-08	62	316
PTKc_Tyro3	cd05074	1.3e-05	62	319
PTKc_Axl	cd05075	0.00095	62	319
PTKc_Ror1	cd05090	0.00024	62	319
PTKc_Ror2	cd05091	4.4e-05	62	319
PTKc_Axl_like	cd05035	5.7e-05	62	319
STKc_SLK_like	cd06611	1.7e-10	62	336
STKc_CDK1_like	cd07835	9.3e-11	62	320
PK_STRAD	cd08216	1.6e-05	63	330
PTKc_Ror	cd05048	1.6e-06	65	273
PTKc_Srm_Brk	cd05148	1.1e-09	65	318
STKc_RSK_N	cd05582	2.7e-24	65	381
STKc_p70S6K	cd05584	2.9e-24	65	383
STKc_MEKK4	cd06626	2.5e-16	65	320
PTKc	cd00192	2e-12	66	316
PTKc_Ack_like	cd05040	1.4e-11	66	317
PTKc_Fes_like	cd05041	1.1e-10	66	317
PTKc_Aatyk	cd05042	2e-06	66	334
PTKc_c-ros	cd05044	1.7e-05	66	317
PTKc_Met_Ron	cd05058	3.5e-06	66	324
PTKc_Syk_like	cd05060	8.6e-08	66	320
PTKc_Fes	cd05084	2.8e-08	66	317
PTKc_Fer	cd05085	1.2e-07	66	317
PTKc_Aatyk1_Aatyk3	cd05087	0.00017	66	349
PTKc_Aatyk2	cd05086	2.8e-05	66	322
PTKc_Syk	cd05116	2e-08	66	324
STKc_CMGC	cd05118	7.3e-23	66	320
STKc_PKC	cd05570	1.3e-18	66	363
STKc_PKB	cd05571	1.2e-30	66	398
STKc_SGK	cd05575	8.7e-11	66	380
STKc_nPKC_eta	cd05590	7.1e-29	66	393
STKc_nPKC_epsilon	cd05591	5.8e-28	66	393
STKc_nPKC_theta_delt	cd05592	2.5e-26	66	382
STKc_PKB_gamma	cd05593	1.4e-12	66	385
STKc_PKB_alpha	cd05594	5.5e-17	66	383
STKc_SGK1	cd05602	1.3e-09	66	382
STKc_SGK2	cd05603	5.4e-14	66	380
STKc_SGK3	cd05604	2.2e-14	66	381
STKc_aPKC	cd05588	2.2e-25	66	390
STKc_PKB_beta	cd05595	6.4e-23	66	360
STKc_aPKC_zeta	cd05617	8.7e-14	66	396
STKc_nPKC_theta	cd05619	7.8e-18	66	379
STKc_nPKC_delta	cd05620	3.9e-12	66	365
STKc_aPKC_iota	cd05618	1.1e-14	66	396
PKc_MAPKK_Byr1_like	cd06620	7.5e-06	66	320
STKc_MEKK1_plant	cd06632	1e-15	66	320
STKc_NAK1_like	cd06917	1e-11	66	348
STKc_MOK	cd07831	3.8e-16	66	320
STKc_CDK5	cd07839	5.5e-09	66	320
STKc_NLK	cd07853	4.6e-09	66	404
STKc_Nek2	cd08217	3.2e-16	66	320
STKc_Nek8	cd08220	8.7e-15	66	320
PTKc_Zap-70	cd05115	5.4e-08	67	341
STKc_Sid2p_Dbf2p	cd05600	3.4e-08	67	383
STKc_OSR1_SPAK	cd06610	2.5e-13	67	320
STKc_MST1_2	cd06612	1.1e-14	67	320
STKc_CdkB_plant	cd07837	1.2e-12	67	321
STKc_CDKL2_3	cd07846	1.8e-10	67	320
PKc	cd00180	2.3e-84	68	318
PTKc_Tie	cd05047	4.4e-05	68	321
STKc_AGC	cd05123	3.1e-39	68	320
STKc_cGK_PKG	cd05572	2.9e-16	68	326
STKc_GRK	cd05577	1.2e-12	68	330
STKc_MAST_like	cd05579	3.4e-19	68	325
STKc_YPK1_like	cd05585	1.4e-22	68	380
STKc_Sck1_like	cd05586	2.8e-13	68	436
STKc_PKN	cd05589	1.3e-20	68	395
STKc_beta_ARK	cd05606	2.8e-10	68	345
STKc_GRK7	cd05607	1e-12	68	350
STKc_GRK1	cd05608	2.3e-17	68	340
STKc_GRK3	cd05633	5.3e-08	68	346
STKc_myosinIII_like	cd06608	6.2e-12	68	320
STKc_YSK4	cd06631	2.7e-14	68	320
STKc_MAPKKK_Bck1_lik	cd06629	2.4e-13	69	325
STKc_Rim15_like	cd05611	4.9e-06	71	312
STKc_NDR_like	cd05599	4.6e-08	89	361
STKc_MAPK15	cd07852	2.3e-12	93	360
Pkinase	pfam00069	4.2e-89	62	320
Pkinase_Tyr	pfam07714	2.9e-16	62	315
TyrKc	smart00219	1.3e-15	62	319
STYKc	smart00221	1.1e-83	62	320
S_TKc	smart00220	1.2e-96	72	320
KIND	smart00750	0.00012	146	328

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs10775648	Polymorphism	p.ARG591CYS	N/A
Swiss-Prot	VAR_040561	Polymorphism	p.ARG157TRP	N/A
Swiss-Prot	VAR_040563	Polymorphism	p.GLU625LYS	N/A
Swiss-Prot	VAR_040564	Polymorphism	p.MET648THR	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258