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  Domain Name: 7TM_GPCR_Srx
Serpentine type 7TM GPCR chemoreceptor Srx. Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srx is part of the Srg superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.
No pairwise interactions found for the domain 7TM_GPCR_Srx

Total Mutations Found: 33
Total Disease Mutations Found: 21
This domain occurred 16 times on human genes (26 proteins).



  DIABETES MELLITUS, TYPE 2, SUSCEPTIBILITY TO
  HYPERTHYROIDISM, NONAUTOIMMUNE
  HYPOTHYROIDISM, CONGENITAL, NONGOITROUS, 1
  SOMATOSTATIN ANALOG, RESISTANCE TO
  THYROID ADENOMA, HYPERFUNCTIONING, SOMATIC
  THYROID ADENOMA, HYPERFUNCTIONING, SOMATIC, INCLUDED
  THYROID CARCINOMA WITH THYROTOXICOSIS


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for 7TM_GPCR_Srx














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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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