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  Domain Name: AAA
ATPase family associated with various cellular activities (AAA). AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.

Total Mutations Found: 25
Total Disease Mutations Found: 16
This domain occurred 43 times on human genes (76 proteins).



  AMYOTROPHIC LATERAL SCLEROSIS 14 WITHOUT FRONTOTEMPORAL DEMENTIA
  MEIER-GORLIN SYNDROME 1
  MEIER-GORLIN SYNDROME 2
  MEIER-GORLIN SYNDROME 5
  MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 1
  PEROXISOME BIOGENESIS DISORDER 4B
  SPASTIC PARAPLEGIA 4
  SPASTIC PARAPLEGIA 7, AUTOSOMAL RECESSIVE
  SPINOCEREBELLAR ATAXIA 28


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 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for AAA











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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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