Home News About DMDM Database Statistics Research Publications Contact  

 
Click for a Larger Image
  Domain Name: Biotin_lipoyl
Biotin-requiring enzyme. This family covers two Prosite entries, the conserved lysine residue binds biotin in one group and lipoic acid in the other. Note that the HMM does not currently recognise the Glycine cleavage system H proteins.
No pairwise interactions found for the domain Biotin_lipoyl

Total Mutations Found: 2
Total Disease Mutations Found: 2
This domain occurred 8 times on human genes (18 proteins).



  3-@METHYLCROTONYL-COA CARBOXYLASE 1 DEFICIENCY
  MAPLE SYRUP URINE DISEASE, CLASSIC, TYPE II


Tips:
 If you've navigated here from a protein, hovering over a position on the weblogo will display the corresponding protein position for that domain position.

 The histograms below the weblogo indicate mutations found on the domain. Red is for disease (OMIM) and blue is for SNPs.

 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Biotin_lipoyl







Weblogos are Copyright (c) 2002 Regents of the University of California




Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

   |   1000 Hilltop Circle, Baltimore, MD 21250   |   Department of Biological Sciences   |   Phone: 410-455-2258